{"product_id":"ultra-high-performance-liquid-chromatography-and-its-applications-isbn-9780470938423","title":"Ultra-High Performance Liquid Chromatography and Its Applications","description":"\u003cp\u003e\u003cb\u003eExplores both the benefits and limitations of new UHPLC technology\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eHigh performance liquid chromatography (HPLC) has been widely used in analytical chemistry and biochemistry to separate, identify, and quantify compounds for decades. The science of liquid chromatography, however, was revolutionized a few years ago with the advent of ultra-high performance liquid chromatography (UHPLC), which made it possible for researchers to analyze sample compounds with greater speed, resolution, and sensitivity.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eUltra-High Performance Liquid Chromatography and Its Applications\u003c\/i\u003e enables readers to maximize the performance of UHPLC as well as develop UHPLC methods tailored to their particular research needs. Readers familiar with HPLC methods will learn how to transfer these methods to a UHPLC platform and vice versa. In addition, the book explores a variety of UHPLC applications designed to support research in such fields as pharmaceuticals, food safety, clinical medicine, and environmental science.\u003c\/p\u003e \u003cp\u003eThe book begins with discussions of UHPLC method development and method transfer between HPLC and UHPLC platforms. It then examines practical aspects of UHPLC. Next, the book covers:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eCoupling UHPLC with mass spectrometry\u003c\/li\u003e \u003cli\u003ePotential of shell particles in fast liquid chromatography\u003c\/li\u003e \u003cli\u003eDetermination of abused drugs in human biological matrices\u003c\/li\u003e \u003cli\u003eAnalyses of isoflavones and flavonoids\u003c\/li\u003e \u003cli\u003eTherapeutic protein characterization\u003c\/li\u003e \u003cli\u003eAnalysis of illicit drugs\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThe final chapter of the book explores the use of UHPLC in drug metabolism and pharmacokinetics studies for traditional Chinese medicine.\u003c\/p\u003e \u003cp\u003eWith its frank discussions of UHPLC's benefits and limitations, \u003ci\u003eUltra-High Performance Liquid Chromatography and Its Applications\u003c\/i\u003e equips analytical scientists with the skills and knowledge needed to take full advantage of this new separation technology.\u003c\/p\u003e  \u003cp\u003ePreface vii\u003c\/p\u003e \u003cp\u003eContributors ix\u003c\/p\u003e \u003cp\u003e1. UHPLC Method Development 1\u003cbr\u003e \u003ci\u003eShujun Chen and Alireza Kord\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2. Method Transfer Between HPLC and UHPLC Platforms 31\u003cbr\u003e \u003ci\u003eGregory K. Webster, Thomas F. Cullen, and Laila Kott\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3. Practical Aspects of Ultrahigh Performance Liquid Chromatography 55\u003cbr\u003e \u003ci\u003eNaijun Wu, Christopher J. Welch, Theresa K. Natishan, Hong Gao, Tilak Chandrasekaran, and Li Zhang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4. Coupling UHPLC with MS: The Needs, Challenges, and Applications 95\u003cbr\u003e \u003ci\u003eJulie Schappler, Serge Rudaz, Jean-Luc Veuthey, and Davy Guillarme\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5. The Potential of Shell Particles in Fast Liquid Chromatography 133\u003cbr\u003e \u003ci\u003eSzabolcs Fekete and Jeno Fekete\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6. UHPLC Determination of Drugs of Abuse in Human Biological Matrices 169\u003cbr\u003e \u003ci\u003eFabio Gosetti, Eleonora Mazzucco, and Maria Carla Gennaro\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7. UHPLC in the Analyses of Isoflavones and Flavonoids 197\u003cbr\u003e \u003ci\u003eSylwia Magiera and Irena Baranowska\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8. UHPLC for Characterization of Protein Therapeutics 235\u003cbr\u003e \u003ci\u003eJennifer C. Rea, Yajun Jennifer Wang, and Taylor Zhang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9. UHPLC\/MS Analysis of Illicit Drugs 253\u003cbr\u003e \u003ci\u003eGuifeng Jiang, Jason R. Stenzel, Ray Chen, and Diab Elmashni\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10. Ultra-High Performance Liquid Chromatography – Mass Spectrometry and Its Application 271\u003cbr\u003e \u003ci\u003eZhili Xiong, Ying Deng, and Famei Li\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 291\u003c\/p\u003e \u003cp\u003e\u003cb\u003eQUANYUN ALAN XU, PhD, \u003c\/b\u003eis a Senior Research Scientist in the Pharmacology and Analytical Laboratory Facility at the University of Texas MD Anderson Cancer Center. Dr. Xu is the coauthor of \u003ci\u003eAnalytical Methods for Therapeutic Drug Monitoring and Toxicology\u003c\/i\u003e as well as more than seventy scientific papers and book chapters.\u003c\/p\u003e   \u003cp\u003e\u003cb\u003eExplores both the benefits and limitations of new UHPLC technology\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eHigh performance liquid chromatography (HPLC) has been widely used in analytical chemistry and biochemistry to separate, identify, and quantify compounds for decades. The science of liquid chromatography, however, was revolutionized a few years ago with the advent of ultra-high performance liquid chromatography (UHPLC), which made it possible for researchers to analyze sample compounds with greater speed, resolution, and sensitivity.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eUltra-High Performance Liquid Chromatography and Its Applications\u003c\/i\u003e enables readers to maximize the performance of UHPLC as well as develop UHPLC methods tailored to their particular research needs. Readers familiar with HPLC methods will learn how to transfer these methods to a UHPLC platform and vice versa. In addition, the book explores a variety of UHPLC applications designed to support research in such fields as pharmaceuticals, food safety, clinical medicine, and environmental science.\u003c\/p\u003e \u003cp\u003eThe book begins with discussions of UHPLC method development and method transfer between HPLC and UHPLC platforms. It then examines practical aspects of UHPLC. Next, the book covers:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eCoupling UHPLC with mass spectrometry\u003c\/li\u003e \u003cli\u003ePotential of shell particles in fast liquid chromatography\u003c\/li\u003e \u003cli\u003eDetermination of abused drugs in human biological matrices\u003c\/li\u003e \u003cli\u003eAnalyses of isoflavones and flavonoids\u003c\/li\u003e \u003cli\u003eTherapeutic protein characterization\u003c\/li\u003e \u003cli\u003eAnalysis of illicit drugs\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThe final chapter of the book explores the use of UHPLC in drug metabolism and pharmacokinetics studies for traditional Chinese medicine.\u003c\/p\u003e \u003cp\u003eWith its frank discussions of UHPLC's benefits and limitations, \u003ci\u003eUltra-High Performance Liquid Chromatography and Its Applications\u003c\/i\u003e equips analytical scientists with the skills and knowledge needed to take full advantage of this new separation technology.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47990423027941,"sku":"NP9780470938423","price":132.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470938423.jpg?v=1761787766","url":"https:\/\/k12savings.com\/products\/ultra-high-performance-liquid-chromatography-and-its-applications-isbn-9780470938423","provider":"K12savings","version":"1.0","type":"link"}