{"product_id":"translational-neuroscience-isbn-9780470960714","title":"Translational Neuroscience","description":"Translational research looks to take the latest innovations made in the laboratory setting to translate findings into effective and sustainable medical interventions and improved preventative measures. Funding support is increasingly tied to practical healthcare outcomes, with this trend likely only to increase in coming years, \u003ci\u003eTranslational Neuroscience: A Guide to a Successful Program\u003c\/i\u003e, is a timely guide to developing research programs that bring translational advances to the forefront.  \u003cp\u003e\u003ci\u003eTranslational Neuroscience\u003c\/i\u003e provides practical information from scientists with first-hand experience in developing a cutting-edge translational facility. The book opens with chapters that provide guidance to organizing a center for translational science. Chapters look at topics ranging from mentoring and career planning for clinician scientists to improving the design of core facilities and addressing infrastructure needs. The second half of the book provides valuable case studies of translational neuroscience in action, with examples ranging from using to transcranial magnetic stimulation to studies on drug abuse and telemedicine applications. The final chapter looks to the future of basic science research, how academic health centers can be reorganized, and how future generations of translational neuroscientists can be trained.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eTranslational Neuroscience\u003c\/i\u003e provides a blueprint to developing an innovative and successful translational research program. Deans, department chairs, academic health center administrators, and researchers will find this guide useful for drafting programs in translational research and avoiding costly pitfalls. While grounded in examples from basic neuroscience research, this book will be a useful tool to all scientists looking to develop centers of translational science across research disciplines.\u003c\/p\u003e \u003cp\u003eContributors xi\u003c\/p\u003e \u003cp\u003ePreface xiii\u003c\/p\u003e \u003cp\u003eAcknowledgments xv\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 A Brief History of Translational Neuroscience 1\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eEdgar Garcia-Rill\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eSome recent history 1\u003c\/p\u003e \u003cp\u003eFunding translational research 3\u003c\/p\u003e \u003cp\u003eLack of funding 4\u003c\/p\u003e \u003cp\u003eMaking NIH funding more equitable and efficient 6\u003c\/p\u003e \u003cp\u003eHow much funding is needed? 7\u003c\/p\u003e \u003cp\u003eMedical research funding in Europe 10\u003c\/p\u003e \u003cp\u003eReferences 13\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Mentoring in Translational Neuroscience 15\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eEdgar Garcia-Rill\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eT1 blocks 15\u003c\/p\u003e \u003cp\u003eT2 blocks 20\u003c\/p\u003e \u003cp\u003eReferences 27\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Core Facilities for Translational Neuroscience 29\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eEdgar Garcia-Rill\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eDesigning translational neuroscience core facilities 31\u003c\/p\u003e \u003cp\u003ePreattentional measure—the P50 potential 33\u003c\/p\u003e \u003cp\u003eAttentional measures—psychomotor vigilance 35\u003c\/p\u003e \u003cp\u003eFrontal lobe blood flow measures 36\u003c\/p\u003e \u003cp\u003eReferences 42\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Translational Studies Using TMS 43\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eMark Mennemeier, Christine Sheffer, Abdallah Hayar, and Roger Buchanan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eOverview 43\u003c\/p\u003e \u003cp\u003eIntroduction 44\u003c\/p\u003e \u003cp\u003eDevelopment of a sham stimulation technique for humans 45\u003c\/p\u003e \u003cp\u003ePET-guided TMS studies of tinnitus perception 46\u003c\/p\u003e \u003cp\u003eTMS investigations of decision-making in tobacco addiction 50\u003c\/p\u003e \u003cp\u003eTMS investigations in rodents 54\u003c\/p\u003e \u003cp\u003eConclusion 61\u003c\/p\u003e \u003cp\u003eReferences 61\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Translational Studies in Drug Abuse 67\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eVeronica Bisagno, William E. Fantegrossi, and Francisco J. Urbano\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eBackground and significance 67\u003c\/p\u003e \u003cp\u003eBehavioral Core Facility 70\u003c\/p\u003e \u003cp\u003eVoltage-sensitive dye imaging 75\u003c\/p\u003e \u003cp\u003eIntravenous drug self-administration 75\u003c\/p\u003e \u003cp\u003eReferences 79\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Electrophysiology in Translational Neuroscience 83\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eEdgar Garcia-Rill\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIn vivo and in vitro animal models 83\u003c\/p\u003e \u003cp\u003eModafinil 84\u003c\/p\u003e \u003cp\u003ePatch clamp recordings 85\u003c\/p\u003e \u003cp\u003eGamma band activity 86\u003c\/p\u003e \u003cp\u003ePopulation responses 88\u003c\/p\u003e \u003cp\u003ePreconscious awareness 89\u003c\/p\u003e \u003cp\u003eMagnetoencephalography, the Cadillac of human electrophysiology 91\u003c\/p\u003e \u003cp\u003eReferences 94\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Translational Research on Spinal Cord Injury 97\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eCharlotte Yates and Kevin Garrison\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eElectrophysiological approach: H-reflex frequency-dependent depression 98\u003c\/p\u003e \u003cp\u003eBiomechanical approach: windup of the stretch reflex 100\u003c\/p\u003e \u003cp\u003eInterventions: passive exercise 101\u003c\/p\u003e \u003cp\u003eInterventions: pharmacology (L-Dopa, Modafinil) 105\u003c\/p\u003e \u003cp\u003eConclusions 106\u003c\/p\u003e \u003cp\u003eReferences 106\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Translational Research in Neonatology 109\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eRichard Whit Hall\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIntroduction 109\u003c\/p\u003e \u003cp\u003eThe need for neonatal research 110\u003c\/p\u003e \u003cp\u003eThe building blocks: basic research 110\u003c\/p\u003e \u003cp\u003ePups to babies and back again: T1 Research 111\u003c\/p\u003e \u003cp\u003eNo problem can be solved unless it is first identified 112\u003c\/p\u003e \u003cp\u003eFrom the bedside to the community: T2 research 113\u003c\/p\u003e \u003cp\u003eThe role of comparative effectiveness research 116\u003c\/p\u003e \u003cp\u003eBarriers and rewards in translational research in neonatology 118\u003c\/p\u003e \u003cp\u003eOpportunities for translational research in neonatology 119\u003c\/p\u003e \u003cp\u003eConclusion 119\u003c\/p\u003e \u003cp\u003eReferences 120\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Telemedicine in Translational Neuroscience 123\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eAmy Ballard and Richard Whit Hall\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eHistory of telemedicine 124\u003c\/p\u003e \u003cp\u003eEnabling access to care 125\u003c\/p\u003e \u003cp\u003eTelemedicine Core Facility 126\u003c\/p\u003e \u003cp\u003eNeonatal intensive care 129\u003c\/p\u003e \u003cp\u003eEmergency departments 131\u003c\/p\u003e \u003cp\u003eConclusion 132\u003c\/p\u003e \u003cp\u003eReferences 132\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Implications for the Future 135\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eEdgar Garcia-Rill\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eFragmented infrastructure 135\u003c\/p\u003e \u003cp\u003eIncompatible databases 136\u003c\/p\u003e \u003cp\u003eThe benefits of translational research 138\u003c\/p\u003e \u003cp\u003eThe reshaping of basic science departments 139\u003c\/p\u003e \u003cp\u003eReferences 142\u003c\/p\u003e \u003cp\u003eIndex 145\u003c\/p\u003e  \u003cp\u003e“This is a useful reference for neuroscience program developers such as basic and clinical scientists, administrators of neuroscience centers, department chairs, and deans.”  (\u003ci\u003eDoody’s\u003c\/i\u003e, 7 September 2012)\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cb\u003eEdgar Garcia-Rill\u003c\/b\u003e is Professor of Anatomy and Psychiatry at the University of Arkansas for Medical Sciences. His research interests include sleep disorders, schizophrenia, depression, PTSD, and aches Neuroscience spinal cord injury. Dr. Garcia-Rill is also Director of the Center for Translational Neuroscience, a didivision of division of the Department of Neurobiology \u0026amp; Dev. Sci. and a research arm of the Jackson T. Stephens Spine \u0026amp; Neuroscience Institute, at which novel treatments for the treatment of spinal cord injury are are being developed under the Spinal Cord Injury Mobilization Program.  Translational research looks to take the latest innovations made in the laboratory setting to translate findings into effective and sustainable medical interventions and improved preventative measures. Funding support is increasingly tied to practical healthcare outcomes, with this trend likely only to increase in coming years, \u003ci\u003eTranslational Neuroscience: A Guide to a Successful Program\u003c\/i\u003e, is a timely guide to developing research programs that bring translational advances to the forefront.  \u003cp\u003e\u003ci\u003eTranslational Neuroscience\u003c\/i\u003e provides practical information from scientists with first-hand experience in developing a cutting-edge translational facility. The book opens with chapters that provide guidance to organizing a center for translational science. Chapters look at topics ranging from mentoring and career planning for clinician scientists to improving the design of core facilities and addressing infrastructure needs. The second half of the book provides valuable case studies of translational neuroscience in action, with examples ranging from using to transcranial magnetic stimulation to studies on drug abuse and telemedicine applications. The final chapter looks to the future of basic science research, how academic health centers can be reorganized, and how future generations of translational neuroscientists can be trained.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eTranslational Neuroscience\u003c\/i\u003e provides a blueprint to developing an innovative and successful translational research program. Deans, department chairs, academic health center administrators, and researchers will find this guide useful for drafting programs in translational research and avoiding costly pitfalls. While grounded in examples from basic neuroscience research, this book will be a useful tool to all scientists looking to develop centers of translational science across research disciplines.\u003c\/p\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47990408544485,"sku":"NP9780470960714","price":105.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470960714.jpg?v=1761787708","url":"https:\/\/k12savings.com\/products\/translational-neuroscience-isbn-9780470960714","provider":"K12savings","version":"1.0","type":"link"}