The Year in Neurology 2, Volume 1184

This second volume in The Year in Neurology series focuses on present reviews covering novel approaches to our understanding neurological diseases through both basic science and clinical approaches. A wide-range of topics is covered within this volume, including:

• vertebrobasilar dolichoectasia
• neurological nanotechnology
• neurologic diseases
• sleep disorders
• chronic inflammatory diseases

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Preface vii

Sleep disorders in children 1

REM sleep behavior disorder: updated review of the core features, the REM sleep behavior disorder-neurodegenerative disease association, evolving concepts, controversies, and future directions 15

Lewy body pathology in fetal grafts 55

Congenital heart disease and brain development 68

The tuberous sclerosis complex 87

Neurological complications of immune reconstitution in HIV-infected populations 106

Vertebrobasilar dilatative arteriopathy (dolichoectasia) 121

Dermatomyositis and polymyositis: clinical presentation, autoantibodies, and pathogenesis 134

Advances in the treatment of neurodegenerative disorders employing nanotechnology 154

Neurologic Wilson's disease 173

The progression of pathology in Parkinson's disease 188

Familial pain syndromes from mutations of the Na[subscript v]1.7 sodium channel 196

Epilepsy in the elderly 208

Flightless flies: Drosophila models of neuromuscular disease E1

Richard T. Johnson, The Johns Hopkins School of Medicine, Baltimore, Maryland.