{"product_id":"the-developing-human-brain-isbn-9781908316417","title":"The Developing Human Brain","description":"\u003cp\u003e\u003cb\u003eClinics in Developmental Medicine\u003c\/b\u003e\u003c\/p\u003e \u003cul\u003e \u003cli\u003eWell over 200 illustrations, many in colour\u003c\/li\u003e \u003cli\u003eCo-authored by two experts in neuropathology and neuroimaging\u003c\/li\u003e \u003cli\u003eTakes a quantitative approach to brain growth in weight, gyrus formation, myelination, and spectroscopy of the developing brain\u003c\/li\u003e \u003cli\u003eThe only book in this field to include chapters in angiogenesis, fetal behaviour, and reactions to chronic illness\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThis book is about human brain development, focusing on the last half of gestation and the neonatal and infant periods. These periods bring the greatest risk for the acquisition of childhood functional neurologic deficits, including cerebral palsy, developmental delay and intellectual disability. Section 1 covers typical development, including growth in brain weight, ventricular surfaces, gyral development, myelinated tract development, magnetic resonance spectroscopy, and angiogenesis, all serving as reference points for section 2, which deals with common acquired brain abnormalities, some of which are often underemphasized or overlooked. The topics in section 2 include retrocerebellar cysts, abnormal events in fetal brain, white-matter abnormalities, lesions of gray and white matter, hemorrhage, ventriculomegaly and hydrocephalus, late expressions of fetal brain disease, and reactions of the developing brain to chronic disease. Between sections 1 and 2 is a chapter on embryonic and fetal physiologic reactions to external stimuli. Where appropriate, the authors have combined pathologic with neuroimaging examples to help the reader better understand the neuroimages that they encounter.\u003c\/p\u003e \u003cp\u003eMuch of the information in the book is based on data from the National Collaborative Perinatal Project, still the only large autopsy survey of late fetal brain lesions.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eReadership:\u003c\/b\u003e Developmental neurobiologists, neuroscientists, paediatricians, neuropathologists, pediatric neuroradiologists, pediatric neurologists, neonatologists, perinatologists.\u003c\/p\u003e \u003cp\u003ePreface vii\u003c\/p\u003e \u003cp\u003eAcknowledgments viii\u003c\/p\u003e \u003cp\u003e1 Introduction 1\u003c\/p\u003e \u003cp\u003eSection 1 11\u003c\/p\u003e \u003cp\u003e2 Brain Growth 13\u003c\/p\u003e \u003cp\u003e3 Fetal Ventricular Size, Surfaces, and Appendages 28\u003c\/p\u003e \u003cp\u003e4 Germinal Tissue (Subventricular Zone) 48\u003c\/p\u003e \u003cp\u003e5 Surface Configuration-Gyral Pattern Development 65\u003c\/p\u003e \u003cp\u003e6 Myelinated Tracts: Growth Patterns 94\u003c\/p\u003e \u003cp\u003e7 Developing Brain Imaging and Magnetic Resonance Spectroscopy 152\u003c\/p\u003e \u003cp\u003e8 Angiogenesis 179\u003c\/p\u003e \u003cp\u003eSection 2 201\u003c\/p\u003e \u003cp\u003e9 Developmental Human Fetal Reactions: Avoid, Squint, Scowl, Sneer, and Pucker 203\u003c\/p\u003e \u003cp\u003e10 Blake's Pouch and Retrocerebellar Cysts: Posterior Fossa Cysts 219\u003c\/p\u003e \u003cp\u003e11 Developmental Central Nervous System Aberration 238\u003c\/p\u003e \u003cp\u003e12 Cerebral White Matter Abnormalities 253\u003c\/p\u003e \u003cp\u003e13 Late Fetal and Perinatal Brain Vascular Abnormalities and Necroses 285\u003c\/p\u003e \u003cp\u003e14 Fetal and Neonatal Intracranial Hemorrhage 328\u003c\/p\u003e \u003cp\u003e15 Ventriculomegaly, Large Head, Megalencephaly, And Hydrocephalus 348\u003c\/p\u003e \u003cp\u003e16 Developing Brain Reactions During Chronic Childhood Disease 380\u003c\/p\u003e \u003cp\u003e17 Concluding Remarks 385\u003c\/p\u003e \u003cp\u003eIndex 389\u003c\/p\u003e \u003cp\u003eColor Plate Section Follows 400\u003c\/p\u003e  \u003cp\u003e“The text is comprehensive, well referenced and supported by numerous illustrations, including pictures, tables and diagrams.  This is a useful resource that takes the reader into a fascinating journey of exploration.”  (\u003ci\u003eNursing Standard\u003c\/i\u003e, 31 October 2012)\u003c\/p\u003e  \u003cp\u003e\u003cstrong\u003eFloyd Gilles\u003c\/strong\u003e heads the pediatric neuropathology program at the Children's Hospital Los Angeles. He is the Burton E. Green Professor of Pediatric Neuropathology at CHLA, and Professor of Pathology (Neuropathology), Neurology, and Neurosurgery at the Keck School of Medicine, University of Southern California. His areas of expertise include the intraoperative interpretation of frozen sections of brain specimens and the neuropathologic aspects of childhood autopsies. His major areas of research interest include the neuropathology of the last half of gestation, pediatric brain tumor identification, classification, prognosis and therapeutic trials; the development of a statistically modeled method of classifying tumors that provides specific five-year survival probabilities and appropriate survival covariates; and telencephalic angiogenesis. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eMarvin Nelson\u003c\/strong\u003e is Chief of the Department of Imaging Services and the John L. Gwinn Professor of Pediatric Radiology at CHLA, and Professor of Radiology at the Keck School of Medicine. He also heads the training program in pediatric radiology and neuroradiology at CHLA. He was a fellow in neuroradiology at the National Hospital for Nervous Diseases, Queen Square, London and the Rothschild Institute, Paris, France, and a fellow in pediatric neuroradiology at Children's Memorial Hospital, Chicago, Illinois. He joined the faculty at CHLA and USC in 1987. His research includes the use of spectroscopy and other advanced imaging techniques in diagnosing such conditions as brain tumors, pediatric acute hydrocephalus and sickle cell disease damage.\u003c\/p\u003e","brand":"Mac Keith Press","offers":[{"title":"Default Title","offer_id":47990205743333,"sku":"NP9781908316417","price":168.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781908316417.jpg?v=1761786899","url":"https:\/\/k12savings.com\/products\/the-developing-human-brain-isbn-9781908316417","provider":"K12savings","version":"1.0","type":"link"}