Sample Preparation Techniques in Analytical Chemistry

The importance of accurate sample preparation techniques cannot be overstated--meticulous sample preparation is essential. Often overlooked, it is the midway point where the analytes from the sample matrix are transformed so they are suitable for analysis. Even the best analytical techniques cannot rectify problems generated by sloppy sample pretreatment.

Devoted entirely to teaching and reinforcing these necessary pretreatment steps, Sample Preparation Techniques in Analytical Chemistry addresses diverse aspects of this important measurement step. These include:
* State-of-the-art extraction techniques for organic and inorganic analytes
* Sample preparation in biological measurements
* Sample pretreatment in microscopy
* Surface enhancement as a sample preparation tool in Raman and IR spectroscopy
* Sample concentration and clean-up methods
* Quality control steps

Designed to serve as a text in an undergraduate or graduate level curriculum, Sample Preparation Techniques in Analytical Chemistry also provides an invaluable reference tool for analytical chemists in the chemical, biological, pharmaceutical, environmental, and materials sciences.Auch die sorgfältigste Analyse versagt, wenn die Proben unachtsam präpariert wurden.

Dieser Band befasst sich mit dem wichtigen, aber oft vernachlässigten Schritt der Probenvorbereitung, erläutert ausführlich jeden Schritt der Extraktion organischer Substanzen aus Flüssigkeiten und Feststoffen und bespricht Methoden der Probenkonditionierung (wie Trocknung und Homogenisierung).

Anschauliche Beispiele, unter anderem aus der Bioanalytik und Umweltchemie, ergänzen dieses einzigartige, für Chemiker und Chemiestudenten unentbehrliche Handbuch. Contributors.

Preface.

Chapter 1. Sample Preparation: An Analytical Perspective (Somenath Mitra and Roman Brukh).

SECTION A: EXTRACTION AND ENRICHMENT IN SAMPLE PREPARATION.

Chapter 2. Principles of Extraction and the Extraction of Semivolatile Organics From Liquids (Martha J.M. Wells).

Chapter 3. Extraction of Semivolatile Organic Compounds From Solid Matrices (Dawen Kou and Somenath Mitra).

Chapter 4. Extraction of Volatile Organic Compounds From Solids and Liquids (Gregory C. Slack, et al.).

Chapter 5. Preparation of Samples for Metals Analysis (Barbara B. Kebbekus).

SECTION B: SAMPLE PREPARATION FOR NUCLEIC ACID ANALYSIS.

Chapter 6. Sample Preparation in DNA Analysis (Satish Parimoo and Bhama Parimmo).

Chapter 7. Sample Preparation in RNA Analysis (Bhama Parimoo and Satish Parimoo).

Chapter 8. Techniques for the Extraction, Isolation and Purification of Nucleic Acids (Mahesh Karwa and Somenath Mitra).

SECTION C: SAMPLE PREPARATION IN MICROSCOPY AND SPECTROSCOPY.

Chapter 9. Sample Preparation for Microscope and Spectroscopic Characterization of Solid Surfaces and Films (Sharmila M. Mukhopadhyay).

Chapter 10. Surface Enhancement by Sample and Substrate Preparation Techniques in Raman and Infrared Spectroscopy (Zafar Iqbal).

Index. "...this book provides a wealth of information in a wide variety of sample preparation techniques. This could be very useful to someone developing a new method or modifying an existing one." (Inside Laboratory Management, July/August 2004)

"There is quite a mixture of analytical isolation techniques covered in this volume. Every analyst will find something of interest in its pages." (Clinical Chemistry, August 2004)

"...covers some of the more important and widely used sample preparation techniques that are crucial to the measurement process." (Journal of the American Chemical Society, Vol. 126, No. 5)

"...a well-written book useful for a professional chemistry collection, or a personal office collection..." (E-Streams, Vol. 7, No. 4)

"...clearly outlines the accepted and preferred practices needed in a modern analytical laboratory...an excellent resource...it should be kept nearby as a resource in any serious analytical lab...essential." (Choice, Vol. 41, No. 8, April 2004)

"This monograph provides a solid and practical overview with depth on this important topic...the book would be very useful to individual analysts, biochemists, environmental scientists, and material scientists, and should certainly be recommended for addition to almost any library collection." (Journal of Chemical Education, February 2004) SOMENATH MITRA. PHD, is Professor of Chemistry and Environmental Science at the New Jersey Institute of Technology. He is coauthor of the textbook Environmental Chemical Analysis. In addition, he has published extensively in peer-reviewed journals of chemistry and analytical sciences. A groundbreaking guide devoted entirely to sample preparations

The importance of accurate sample preparation techniques cannot be overstated. Meticulous sample preparation is essential. Often overlooked, it is the midway poi nt where the analytes from the sample matrix are transformed so they are suitable for analysis. Even the best analytical techniques cannot rectify problems generated by sloppy sample pretreatment Devoted entirely to teaching and reinforcing these necessary pretreatment steps, Sample Preparation Techniques in Analytical Chemistry addresses diverse aspects of this important measurement step. , These include:

• State-of-the-art extraction techniques for organic and inorganic analytes
• Sample preparation in biological measurements
• Sample pretreatment in microscopy
• Surface enhancement as a sample preparation tool in Raman and IR spectroscopy
• Sample concentration and clean-up methods
• Quality control steps

Sample Preparation Techniques in Analytical Chemistry is an invaluable reference tool for Analytical Chemists in chemical, biological, pharmaceutical, environmental, and material sciences.