{"product_id":"rett-syndrome-isbn-9781909962835","title":"Rett Syndrome","description":"Among the vast body of literature that has grown around Rett syndrome, this volume is the first to be aimed at both clinicians and researchers. It presents a comprehensive overview of the disorder and examines the areas where gaps in knowledge are most significant.  \u003ci\u003eRett Syndrome\u003c\/i\u003e is intended to be a guide for both initial examination and in-depth study of the disorder.   It is a practical text for the physician approaching the disorder for the first time and a valuable reference resource for the specialist or researcher. \u003cp\u003eAuthors’ Appointments vii\u003c\/p\u003e \u003cp\u003eForeword xi\u003c\/p\u003e \u003cp\u003eBengt Hagberg : Leading the Way to Rett Syndrome Today xiii\u003cbr\u003e \u003ci\u003eA tribute by Dr Alan K Percy\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003ePreface xv\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePrologue: Personal Perspectives\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eMy ‘Rett’ Story xvii\u003cbr\u003e \u003ci\u003eBengt Hagberg\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eA Mother’s Journey xix\u003cbr\u003e \u003ci\u003eKathy Hunter\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eA Perspective from the British Isles xxii\u003cbr\u003e \u003ci\u003eAlison Kerr\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1. The Diagnosis of Rett Syndrome 1\u003cbr\u003e \u003ci\u003eWalter E Kaufmann and Jeffrey L Neul\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2. The Natural History of Rett Syndrome: Building on Recent Experience 14\u003cbr\u003e \u003ci\u003eAlan K Percy and Daniel G Glaze\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3. The Clinical Genetics of Rett Syndrome 24\u003cbr\u003e \u003ci\u003eHayley Archer, John Christodoulou and Angus Clarke\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4. Genetic Sources of Variation in Rett Syndrome 41\u003cbr\u003e \u003ci\u003eSonia Bjorum Brower, Helen Leonard, Francesca Mari, Alessandra Renieri and Jeffrey L Neul\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5. Cognition, Communication and Behavior in Individuals with Rett Syndrome 50\u003cbr\u003e \u003ci\u003eGillian S Townend, Walter E Kaufmann, Peter B Marschik, Rosa Angela Fabio, Jeff Sigafoos and Leopold MG Curfs\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6. Motor Abnormalities in Rett Syndrome 62\u003cbr\u003e \u003ci\u003eJenny Downs and Teresa Temudo\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7. Orthopedic Isssues in Rett Syndrome 75\u003cbr\u003e \u003ci\u003eDavid P Roye Jr, Jenny Downs, Gordon Baikie and Brendan A Williams\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8. Sleep Issues in Rett Syndrome 91\u003cbr\u003e \u003ci\u003eDaniel G Glaze, Sarojini Budden, Yoshiko Nomura and Carolyn Ellaway\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9. Epilepsy in Rett Syndrome 103\u003cbr\u003e \u003ci\u003eAndreea Nissenkorn, Maria Pintaudi, Daniel G Glaze and Bruria Ben-Zeev\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10. Breathing Abnormalities in Rett Syndrome 116\u003cbr\u003e \u003ci\u003eJan Marino Ramirez, Christopher Scott Ward and Jeffrey L Neul\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11. Growth, Feeding an Nutrition, an Bone Health in Rett Syndrome 125\u003cbr\u003e \u003ci\u003eKathleen J Motil\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12. Molecular Complexities of Mecp2 Function in Rett Syndrome 142\u003cbr\u003e \u003ci\u003eMichael L Gonzales and Janine M LaSalle\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13. The Neuro Biology of Rett Syndrome 153\u003cbr\u003e \u003ci\u003eWalter E Kaufmann, James H Eubanks, Michael V Johnston and Mary E Blue\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14. Treatments for Rett Syndrome: Prospects for Targeted Therapies 170\u003cbr\u003e \u003ci\u003eWendy A Gold, SakkuBai Naidu and John Christodoulou\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15. Rehabilitation in Rett Syndrome 198\u003cbr\u003e \u003ci\u003eSarojini Budden\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16. Perspectives in Rett Syndrome: Where We Are and Where We Should Go 210\u003cbr\u003e \u003ci\u003eWalter E Kaufmann, Alan K Percy, Angus Clarke, Helen Leonard and SakkuBai Naidu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 217\u003c\/p\u003e Walter Kaufmann is Director of the Center for Translational Research and Curry Chair in Genetic Therapeutics at the Greenwood Genetic Center, South Carolina, USA. He is a clinician and researcher whose career has focused on characterizing the neurobehavioral phenotypes and underlying mechanisms of genetic disorders associated with intellectual disability and autism. His focus is the development of novel therapies for these disorders, including outcome measures and biomarkers for the corresponding clinical trials. Dr Kaufmann has carried out most of this work at the Kennedy Krieger Institute and Harvard Medical School (Boston Childrens Hospital) USA.  Alan Percy is a Professor in Child Neurology and currently the Interim Director of Clinical Neuroscience at the Civitan International Research Center, University of Alabama School of Medicine, Birmingham , USA. He trained in paediatrics at Stanford University Hospital and specialised in paediatric neurology at the Johns Hopkins University School of Medicine. Rett syndrome is his main interest. He has authored over 250 monographs, book chapters and journal articles.  He is co-editor of the journal Translational Science of Rare Diseases and is on the Advisory Board of Rettsyndrome.org.   Angus Clarke is Professor and Honorary Consultant in Clinical Genetics at the Institute of Medical Genetics, University Hospital of Wales, UK. He established the Cardiff University MSc course in Genetic Counselling in 2000 and has been Course Director since then. Professor Clarke has particular interest in Rett syndrome and ectodermal dysplasia, the genetic counselling process and the social and ethical issues around human genetics. He has authored or edited seven books and numerous research papers and book chapters. His is also medical advisor to Rett UK.   Helen Leonard is Senior Research Fellow and Principal Research Fellow at the Telethon Kids Institute, Perth, Western Australia.  In 1992 she established the internationally unique, population-based Australian Rett Syndrome Database and has maintained the register since that time. In 2002 she set up the International Rett Syndrome Foundation Phenotype Database, InterRett, which has now collected data on almost 2700 cases from 57 countries. Her international reputation has been built on over 200 peer-reviewed papers and 12 book chapters.  Sakkubai Naidu works as a Pediatric Neurologist at Kennedy Krieger Institute where she also directs Rett syndrome research at the Department of Neurogenetics. Dr Naidu is also a Professor in the Departments of Neurology and Pediatrics at the Johns Hopkins University School of Medicine. Her special interest is in developmental and neurogenetic disorders affecting children and adults. Dr Naidu is a member of the American Academy of Neurology, Child Neurology Society, American Neurological Association, International Child Neurology Society, Neurological Society of India and the American Association for the Advancement of Science.","brand":"Mac Keith Press","offers":[{"title":"Default Title","offer_id":47989958312165,"sku":"NP9781909962835","price":103.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781909962835.jpg?v=1761786029","url":"https:\/\/k12savings.com\/products\/rett-syndrome-isbn-9781909962835","provider":"K12savings","version":"1.0","type":"link"}