{"product_id":"resolving-erroneous-reports-in-toxicology-and-therapeutic-drug-monitoring-isbn-9781118149652","title":"Resolving Erroneous Reports in Toxicology and Therapeutic Drug Monitoring","description":"\u003cp\u003e\u003cb\u003eThe tools for detecting false positives, false negatives, and interference in interactions when testing and monitoring therapeutic drug use\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eFor physicians monitoring a patient's progress, efficacy of treatment is often linked to a patient's response to medication. Determining whether a patient is taking the prescribed amount, the drug or dosage is effective, or the prescribed medication is interacting with other drugs can be determined through drug testing. Written as a guide for toxicologists, chemists, and health professionals involved in patient care, \u003ci\u003eResolving Erroneous Reports in Toxicology and Therapeutic Drug Monitoring\u003c\/i\u003e provides an up-to-date introduction to the tests and methodologies used in a toxicology lab as well as the sources of testing error that can lead to false positives, false negatives, and unreliable conclusions of drug abuse or under use.\u003c\/p\u003e \u003cp\u003eCovering a host of common therapeutic drugs as well as specific types of interference in immunoassays used in drug testing, the book details a number of possible testing scenarios and problems as well as solutions:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eFalse positive results in immunoassays for drugs in abuse testing\u003c\/li\u003e \u003cli\u003eInterferences in immunoassays used for monitoring anticonvulsants, tricyclic antidepressants, and digoxin\u003c\/li\u003e \u003cli\u003eFalse positive alcohol tests using breath analyzers and automated analyzers\u003c\/li\u003e \u003cli\u003eWhen a toxicology report is negative in a suspected overdose patient: the world of designer drugs\u003c\/li\u003e \u003cli\u003eEffects of drug-herb interactions on therapeutic drug monitoring\u003c\/li\u003e \u003cli\u003ePharmacogenomics and the general principles of genetic analysis\u003c\/li\u003e \u003cli\u003eApproaches for eliminating interference\/discordant specimen in therapeutic drug monitoring and drugs in abuse testing\u003c\/li\u003e \u003cli\u003eWhat to do in case there is no readily available method for testing\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eComplete with easy-to-read tables and flowcharts, this book helps toxicologists, clinical chemists, clinical pathologists, and forensic pathologists develop accurate, unbiased drug monitoring and toxicology reports. Health care professionals involved in patient care, especially of critically ill patients, will find this guide indispensable in making sure lab tests are reliable enough to provide high-quality care. An indispensable handbook to the entire suite of toxicology lab tests, as well as all the possible sources of testing error, \u003ci\u003eResolving Erroneous Reports in Toxicology and Therapeutic Drug Monitoring\u003c\/i\u003e offers clear remedies for eliminating and preventing testing error.\u003c\/p\u003e  \u003cp\u003ePreface vii\u003c\/p\u003e \u003cp\u003eChapter 1 An Introduction to Tests Performed in Toxicology Laboratories 1\u003c\/p\u003e \u003cp\u003eChapter 2 Challenges in Drugs of Abuse Testing 31\u003c\/p\u003e \u003cp\u003eChapter 3 False-Positive Results Using Immunoassays for Drugs of Abuse Testing 53\u003c\/p\u003e \u003cp\u003eChapter 4 True-Positive Drugs of Abuse Test Results Due to Use of Prescriptions and Nonprescription Drugs 67\u003c\/p\u003e \u003cp\u003eChapter 5 When Toxicology Report Is Negative in a Suspected Overdosed Patient:\u003c\/p\u003e \u003cp\u003eThe World of Designer Drugs 85\u003c\/p\u003e \u003cp\u003eChapter 6 Abuse of Magic Mushrooms, Peyote Cactus, Khat, and Solvents: No Readily Available Laboratory Tests 101\u003c\/p\u003e \u003cp\u003eChapter 7 Limitations of Blood Alcohol Measurements Using Automated Analyzers and Breath Analyzers 121\u003c\/p\u003e \u003cp\u003eChapter 8 Role of the Laboratory in Detecting Other Poisoning, Including Pesticides, Ethylene Glycol, and Methanol 139\u003c\/p\u003e \u003cp\u003eChapter 9 Poisoning with Warfarin and Superwarfarin: What Can Laboratory Testing Do? 161\u003c\/p\u003e \u003cp\u003eChapter 10 Plant Poisoning and the Clinical Laboratory 185\u003c\/p\u003e \u003cp\u003eChapter 11 Sources of Erroneous Results in Therapeutic Drug Monitoring Due to Preanalytical Errors, High Bilirubin, Hemolysis, and Lipids 213\u003c\/p\u003e \u003cp\u003eChapter 12 Challenges in Therapeutic Drug Monitoring of Digoxin Using Immunoassays 237\u003c\/p\u003e \u003cp\u003eChapter 13 Interference in Immunoassays Used for Monitoring Anticonvulsants and the Usefulness of Monitoring Free Anticonvulsants 265\u003c\/p\u003e \u003cp\u003eChapter 14 Interference in Immunoassays Used to Monitor Tricyclic Antidepressants 293\u003c\/p\u003e \u003cp\u003eChapter 15 Therapeutic Drug Monitoring of Immunosuppressants: Limitations of Immunoassays and the Need for Chromatographic Methods 323\u003c\/p\u003e \u003cp\u003eChapter 16 Effect of Drug–Herb Interactions on Therapeutic Drug Monitoring 355\u003c\/p\u003e \u003cp\u003eChapter 17 Pharmacogenomics and the Toxicology Laboratory 385\u003c\/p\u003e \u003cp\u003eChapter 18 Approaches for Eliminating Interference\/Discordant Specimens in Therapeutic Drug Monitoring and Drugs of Abuse Testing 411\u003c\/p\u003e \u003cp\u003eIndex 429\u003c\/p\u003e \u003cp\u003e\u003cb\u003eAMITAVA DASGUPTA\u003c\/b\u003e is a Professor in the Department of Pathology and Laboratory Medicine at the University of Texas Medical School at Houston and the director of clinical chemistry, toxicology, and point of care testing at the Memorial Hermann Hospital. He is the author of \u003ci\u003eHerbal Supplements\u003c\/i\u003e and \u003ci\u003ePharmacogenomics in Clinical Therapeutics\u003c\/i\u003e, both published by Wiley.\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eThe tools for detecting false positives, false negatives, and interference in interactions when testing and monitoring therapeutic drug use\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eFor physicians monitoring a patient's progress, efficacy of treatment is often linked to a patient's response to medication. Determining whether a patient is taking the prescribed amount, the drug or dosage is effective, or the prescribed medication is interacting with other drugs can be determined through drug testing. Written as a guide for toxicologists, chemists, and health professionals involved in patient care, \u003ci\u003eResolving Erroneous Reports in Toxicology and Therapeutic Drug Monitoring\u003c\/i\u003e provides an up-to-date introduction to the tests and methodologies used in a toxicology lab as well as the sources of testing error that can lead to false positives, false negatives, and unreliable conclusions of drug abuse or under use.\u003c\/p\u003e \u003cp\u003eCovering a host of common therapeutic drugs as well as specific types of interference in immunoassays used in drug testing, the book details a number of possible testing scenarios and problems as well as solutions:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eFalse positive results in immunoassays for drugs in abuse testing\u003c\/li\u003e \u003cli\u003eInterferences in immunoassays used for monitoring anticonvulsants, tricyclic antidepressants, and digoxin\u003c\/li\u003e \u003cli\u003eFalse positive alcohol tests using breath analyzers and automated analyzers\u003c\/li\u003e \u003cli\u003eWhen a toxicology report is negative in a suspected overdose patient: the world of designer drugs\u003c\/li\u003e \u003cli\u003eEffects of drug-herb interactions on therapeutic drug monitoring\u003c\/li\u003e \u003cli\u003ePharmacogenomics and the general principles of genetic analysis\u003c\/li\u003e \u003cli\u003eApproaches for eliminating interference\/discordant specimen in therapeutic drug monitoring and drugs in abuse testing\u003c\/li\u003e \u003cli\u003eWhat to do in case there is no readily available method for testing\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eComplete with easy-to-read tables and flowcharts, this book helps toxicologists, clinical chemists, clinical pathologists, and forensic pathologists develop accurate, unbiased drug monitoring and toxicology reports. Health care professionals involved in patient care, especially of critically ill patients, will find this guide indispensable in making sure lab tests are reliable enough to provide high-quality care. An indispensable handbook to the entire suite of toxicology lab tests, as well as all the possible sources of testing error, \u003ci\u003eResolving Erroneous Reports in Toxicology and Therapeutic Drug Monitoring\u003c\/i\u003e offers clear remedies for eliminating and preventing testing error.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989949858021,"sku":"NP9781118149652","price":153.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781118149652.jpg?v=1761786008","url":"https:\/\/k12savings.com\/products\/resolving-erroneous-reports-in-toxicology-and-therapeutic-drug-monitoring-isbn-9781118149652","provider":"K12savings","version":"1.0","type":"link"}