{"product_id":"regulating-with-rna-in-bacteria-and-archaea-isbn-9781683670230","title":"Regulating with RNA in Bacteria and Archaea","description":"\u003cp\u003e\u003cb\u003eRevealing the many roles of RNA in regulating gene expression\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eFor decades after the discoveries of messenger RNA, transfer RNA, and ribosomal RNA, it was largely assumed that the role of RNA in the cell was limited to shuttling the genomic message, chaperoning amino acids, and toiling in the ribosomes.\u003c\/p\u003e \u003cp\u003eEventually, hints that RNA molecules might have regulatory roles began to appear. With the advent of genomics and bioinformatics, it became evident that numerous other RNA forms exist and have specific functions, including small RNAs (sRNA), RNA thermometers, and riboswitches to regulate core metabolic pathways, bacterial pathogenesis, iron homeostasis, quorum sensing, and biofilm formation.\u003c\/p\u003e \u003cp\u003eAll of these functions, and more, are presented in Regulating with RNA in Bacteria and Archaea, written by RNA biologists from around the globe. Divided into eight sections-RNases and Helicases, Cis-Acting RNAs, Cis Encoded Base Pairing RNAs, Trans-Encoded Base Pairing RNAs, Protein Titration and Scaffolding, General Considerations, Emerging Topics, and Resources-this book serves as an excellent resource for established RNA biologists and for the many scientists who are studying regulated cellular systems.\u003c\/p\u003e \u003cp\u003eIt is no longer a fair assumption that gene expression regulation is the provenance of proteins only or that control is exerted primarily at the level of transcription. This book makes clear that regulatory RNAs are key partners along with proteins in controlling the complex interactions and pathways found within prokaryotes.\u003c\/p\u003e \u003cp\u003eContributors\u003c\/p\u003e \u003cp\u003eForeword\u003c\/p\u003e \u003cp\u003ePreface\u003c\/p\u003e \u003cp\u003eAcknowledgments\u003c\/p\u003e \u003cp\u003eAbout the Editors\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection I: RNases and Helicases\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1. RNase E and the High-Fidelity Orchestration of RNA Metabolism\u003cbr\u003e\u003ci\u003eKatarzyna J. Bandyra and Ben F. Luisi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2. Enzymes Involved in Posttranscriptional RNA Metabolism in Gram-Negative Bacteria\u003cbr\u003e\u003ci\u003eBijoy K. Mohanty and Sidney R. Kushner\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3. RNases and Helicases in Gram-Positive Bacteria\u003cbr\u003e\u003ci\u003eSylvain Durand and Ciarán Condon\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection II: Cis-acting RNAs\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4. RNA Thermometers in Bacterial Pathogens\u003cbr\u003e\u003ci\u003eEdmund Loh, Francesco Righetti, Hannes Eichner, Christian Twittenhoff, Franz Narberhaus\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5. Small Molecule-Binding Riboswitches\u003cbr\u003e\u003ci\u003eThea S. Lotz and Beatrix Suess\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6. The T-Box Riboswitch: tRNA as an Effector to Modulate Gene Regulation\u003cbr\u003e\u003ci\u003eKiel D. Kreuzer and Tina M. Henkin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7. rRNA Mimicry in RNA Regulation of Gene Expression\u003cbr\u003e\u003ci\u003eMichelle M. Meyer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8. Processive Antitermination\u003cbr\u003e\u003ci\u003eJonathan R. Goodson and Wade C. Winkler\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9. Genes within genes in bacterial genomes\u003cbr\u003e\u003ci\u003eSezen Meydan, Nora Vázquez-Laslop, and Alexander S. Mankin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10. Leaderless mRNAs in the Spotlight: Ancient but Not Outdated!\u003cbr\u003e\u003ci\u003eHeather J. Beck and Isabella Moll\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection III: Cis-encoded base pairing RNAs\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11. Type I Toxin-Antitoxin Systems: Regulating Toxin Expression via Shine-Dalgarno Sequence Sequestration and Small RNA Binding\u003cbr\u003e\u003ci\u003eSara Masachis and Fabien Darfeuille\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12. Widespread Antisense Transcription in Prokaryotes\u003cbr\u003e\u003ci\u003eJens Georg and Wolfgang R. Hess\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection IV: Trans-encoded base pairing RNAs \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e13. Small Regulatory RNAs in the Enterobacterial Response to Envelope Damage and Oxidative Stress\u003cbr\u003e\u003ci\u003eKathrin S. Fröhlich and Susan Gottesman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14. Carbohydrate Utilization in Bacteria: Making the Most Out of Sugars with the Help of Small Regulatory RNAs\u003cbr\u003e\u003ci\u003eSvetlana Durica-Mitic, Yvonne Göpel, Boris Görke\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15. Small RNAs Involved in Regulation of Nitrogen Metabolism\u003cbr\u003e\u003ci\u003eDaniela Prasse and Ruth A. Schmitz\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16. Bacterial Iron Homeostasis Regulation by sRNAs\u003cbr\u003e\u003ci\u003eSylvia Chareyre and Pierre Mandin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17. Small-RNA-Based Regulation of Bacterial Quorum Sensing and Biofilm Formation\u003cbr\u003e\u003ci\u003eSine Lo Svenningsen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18. Regulatory RNAs in Virulence and Host-Microbe Interactions\u003cbr\u003e\u003ci\u003eAlexander J. Westermann\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection V: Protein titration and scaffolding\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e19. Global Regulation by CsrA and Its sRNA Antagonists\u003cbr\u003e\u003ci\u003eTony Romeo and Paul Babitzke\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e20. 6S RNA, a Global Regulator of Transcription\u003cbr\u003e\u003ci\u003eKaren M. Wassarman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e21. Bacterial Y RNAs: Gates, Tethers, and tRNA Mimics\u003cbr\u003e\u003ci\u003eSoyeong Sim and Sandra L. Wolin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection VI: General considerations\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e22. Proteins That Chaperone RNA Regulation\u003cbr\u003e\u003ci\u003eSarah A. Woodson, Subrata Panja, and Andrew Santiago-Frangos\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e23. Epitranscriptomics: RNA Modifications in Bacteria and Archaea\u003cbr\u003e\u003ci\u003eKatharina Höfer and Andres Jäschke\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e24. RNA Localization in Bacteria\u003cbr\u003e\u003ci\u003eJingyi Fei and Cynthia M. Sharma\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e25. Sponges and Predators in the Small RNA World\u003cbr\u003e\u003ci\u003eNara Figueroa‐Bossi and Lionello Bossi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e26. Bacterial Small RNAs in Mixed Regulatory Networks\u003cbr\u003e\u003ci\u003eAnaïs Brosse and Maude Guillier\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e27. Dual-Function RNAs\u003cbr\u003e\u003ci\u003eMedha Raina, Alisa King, Colleen Bianco, and Carin K. Vanderpool\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e28. Origin, Evolution, and Loss of Bacterial Small RNAs\u003cbr\u003e\u003ci\u003eH. Auguste Dutcher and Rahul Raghavan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection VII: Emerging topics\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e29. Cross-regulation between bacteria and phages at a posttranscriptional Level\u003cbr\u003e\u003ci\u003eShoshy Altuvia, Gisela Storz, Kai Papenfort\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e30. Large Noncoding RNAs in Bacteria\u003cbr\u003e\u003ci\u003eKimberly A. Harris and Ronald R. Breaker\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e31. Synthetic Biology of Small RNAs and Riboswitches\u003cbr\u003e\u003ci\u003eJordan K. Villa, Yichi Su, Lydia M. Contreras, Ming C. Hammond\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection VIII: Resources\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e32. Functional Transcriptomics for Bacterial Gene Detectives\u003cbr\u003e\u003ci\u003eBlanca Perez-Sepulveda and Jay C.D. Hinton\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e33. Structure and Interaction Prediction in Prokaryotic RNA Biology\u003cbr\u003e\u003ci\u003ePatrick R. Wright, Martin Mann, Rolf Backofen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex\u003c\/p\u003e   \u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003eFinally! One spectacular volume provides us all we need to educate ourselves in the fascinating world of regulatory RNAs in bacteria and archaea. From the genetics to the biochemistry to the mechanisms to the structures to the physiology to the networks to the challenges for the future—it's all here—laid out for us in exceptional form by the world's key experts. This volume is an eye-opening must read about one of microbiology's most exciting emerging fields.\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan lang=\"EN-CA\"\u003e-Bonnie L. Bassler, Ph.D.\u003c\/span\u003e\u003c\/b\u003e\u003cspan lang=\"EN-CA\"\u003e, HHMI Investigator, Squibb Professor and Chair of the Department of Molecular Biology, Princeton University\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003e \u003cp\u003e\u003cb\u003eGisela Storz\u003c\/b\u003e is an NIH Distinguished Investigator in the Eunice Kennedy Shriver National Institute of Child Health and Human Development in Bethesda, Maryland. She carried out graduate work with Dr. Bruce Ames at the University of California, Berkeley and postdoctoral work with Dr. Sankar Adhya at the National Cancer Institute and Dr. Fred Ausubel at Harvard Medical School. As a result of the serendipitous discovery of the peroxide-induced OxyS RNA in \u003ci\u003eE. coli\u003c\/i\u003e, one of the first small, regulatory RNAs to be found, much of the work in her lab has focused on the genome-wide identification of small RNAs and their characterization.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eKai Papenfort\u003c\/b\u003e is a Professor of Microbiology at the Ludwig Maximilians University of Munich, Germany. He received a diploma in biology from the University of Marburg and carried out graduate work with Dr. Jörg Vogel at the Max Planck Institute for Infection Biology and the Humboldt University of Berlin. In his postdoctoral work at the University of Würzburg and Princeton University, Dr. Papenfort studied the regulatory functions of small RNA in bacterial pathogens and their involvement in bacterial communication processes such as quorum sensing. His laboratory focuses on the molecular mechanisms underlying the regulation by small RNAs in the major human pathogen, \u003ci\u003eVibrio cholerae\u003c\/i\u003e.\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eRegulating with RNA in Bacteria and Archaea\u003c\/b\u003e \u003c\/p\u003e\n\u003cp\u003eFirst Edition \u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eRevealing the many roles of RNA in regulating gene expression\u003c\/i\u003e  \u003c\/p\u003e\n\u003cp\u003eFor decades after the discoveries of messenger RNA, transfer RNA, and ribosomal RNA, it was largely assumed that the role of RNA in the cell was limited to shuttling the genomic message, chaperoning amino acids, and toiling in the ribosomes.  \u003c\/p\u003e\n\u003cp\u003eEventually, hints that RNA molecules might have regulatory roles began to appear. With the advent of genomics and bioinformatics, it became evident that numerous other RNA forms exist and have specific functions, including small RNAs (sRNA), RNA thermometers, and riboswitches to regulate core metabolic pathways, bacterial pathogenesis, iron homeostasis, quorum sensing, and biofilm formation.  \u003c\/p\u003e\n\u003cp\u003eAll of these functions, and more, are presented in Regulating with RNA in Bacteria and Archaea, written by RNA biologists from around the globe. Divided into eight sections-RNases and Helicases, Cis-Acting RNAs, Cis Encoded Base Pairing RNAs, Trans-Encoded Base Pairing RNAs, Protein Titration and Scaffolding, General Considerations, Emerging Topics, and Resources-this book serves as an excellent resource for established RNA biologists and for the many scientists who are studying regulated cellular systems.  \u003c\/p\u003e\n\u003cp\u003eIt is no longer a fair assumption that gene expression regulation is the provenance of proteins only or that control is exerted primarily at the level of transcription. This book makes clear that regulatory RNAs are key partners along with proteins in controlling the complex interactions and pathways found within prokaryotes.\u003c\/p\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"ASM Press","offers":[{"title":"Default Title","offer_id":47989930950885,"sku":"NP9781683670230","price":150.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781683670230.jpg?v=1761785951","url":"https:\/\/k12savings.com\/products\/regulating-with-rna-in-bacteria-and-archaea-isbn-9781683670230","provider":"K12savings","version":"1.0","type":"link"}