{"product_id":"recent-advances-in-polyphenol-research-volume-8-isbn-9781119844761","title":"Recent Advances in Polyphenol Research, Volume 8","description":"\u003cp\u003ePlant polyphenols are specialized metabolites that constitute one of the most common and widespread groups of natural products. They are essential plant components for adaptation to the environment and possess a large and diverse range of biological functions that provide many benefits to both plants and humans. Polyphenols, from their structurally simplest forms to their oligo\/polymeric versions (i.e. tannins and lignins), are phytoestrogens, plant pigments, antioxidants, and structural components of the plant cell wall. The interactions between tannins and proteins are involved in plant defense against predation, cause astringency in foods and beverages, and affect the nutritional and health properties of human and animal food plants. \u003c\/p\u003e\u003cp\u003eThis eighth volume of the highly regarded Recent Advances in Polyphenol Research series is edited by Juha-Pekka Salminen, Kristiina Wähälä, Victor de Freitas, and Stéphane Quideau, and brings together chapters written by some of the leading experts working in the polyphenol sciences today. Topics covered include: \u003c\/p\u003e\u003cul\u003e \u003cli\u003eStructure, reactivity and synthesis\u003c\/li\u003e \u003cli\u003eBioactivity and bioavailability\u003c\/li\u003e \u003cli\u003eMetabolomics, targeted analysis and big data\u003c\/li\u003e \u003cli\u003eQuality control \u0026amp; standardization\u003c\/li\u003e \u003cli\u003eBiogenesis and functions in plants and ecosystems\u003c\/li\u003e \u003cli\u003eBiomaterials \u0026amp; applied sciences\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eDistilling the most recent and illuminating data available, this new volume is an invaluable resource for chemists, biochemists, plant scientists, pharmacognosists and pharmacologists, biologists, ecologists, food scientists and nutritionists. \u003c\/p\u003e\u003cp\u003eContributors\u003c\/p\u003e \u003cp\u003ePreface\u003c\/p\u003e \u003cp\u003eAcknowledgements\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Lignins and Lignification: New Developments and Emerging Concepts\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eJohn Ralph, Hoon Kim, Fachuang Lu, Rebecca A. Smith, Steven D. Karlen, Nuoendagula, Koichi Yoshioka, Alexis Eugene, Sarah Liu, Canan Sener, Daisuke Ando, Mingjie Chen, Yanding Li, Leta L. Landucci, Sally A. Ralph, Vitaliy I. Timokhin, Wu Lan, Jorge Rencoret, José C. del Río\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1.1 Introduction\u003c\/p\u003e \u003cp\u003e1.2 The monolignol pathway and interacting pathways -- New lignins\u003c\/p\u003e \u003cp\u003e1.3 Lignin conjugates, 'clip-offs' -- new discoveries, and enhancing levels\u003c\/p\u003e \u003cp\u003e1.4 Features of lignification, and the possibility of new polymerization pathways\u003c\/p\u003e \u003cp\u003e1.5 The value of model studies and synthesis -- a reminder\u003c\/p\u003e \u003cp\u003e1.6 New or improved analytics\u003c\/p\u003e \u003cp\u003e1.7 Conclusions and Opportunities\u003c\/p\u003e \u003cp\u003e\u003ci\u003e2 Synthesis of epigallocatechin gallate, nobiletin and their derivatives for chemical-biology studies\u003c\/i\u003e\u003cbr\u003e\u003ci\u003eTomohiro Asakawa, Makoto Inai and Toshiyuki Kan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2.1 Synthetic investigations of catechin derivatives\u003c\/p\u003e \u003cp\u003e2.2 Synthesis and application of fluorescent catechin probes\u003c\/p\u003e \u003cp\u003e2.3 Generation of catechin antibody\u003c\/p\u003e \u003cp\u003e2.4 PET imaging of biodistribution of catechin\u003c\/p\u003e \u003cp\u003e2.5 Practical synthesis of nobiletin\u003c\/p\u003e \u003cp\u003e2.6 Derivatization of desmethyl nobiletins\u003c\/p\u003e \u003cp\u003e2.7 PET imaging of biodistribution of nobiletin\u003c\/p\u003e \u003cp\u003e2.8 Synthesis and application of fluorescent nobiletin probe\u003c\/p\u003e \u003cp\u003e2.9 Conclusions\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Procyanidins in the Onset and Progression of Colorectal Cancer: Recent Advances and Open Questions\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eWei Zhu, Gerardo G. Mackenzie and Patricia I. Oteiza\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction\u003c\/p\u003e \u003cp\u003e3.2 Procyanidins:chemistry and metabolism\u003c\/p\u003e \u003cp\u003e3.3 Procyanidins and CRC: epidemiological evidence\u003c\/p\u003e \u003cp\u003e3.4 Procyanidins and CRC: rodent studies\u003c\/p\u003e \u003cp\u003e3.5 Procyanidins and CRC: mechanisms of actions\u003c\/p\u003e \u003cp\u003e3.6 Conclusions and open questions\u003c\/p\u003e \u003cp\u003e3.7 Acknowledgements\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 The Potential of Low Molecular Weight (Poly)phenol Metabolites for Attenuating Neuroinflammation and Treatment of Neurodegenerative Diseases\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eDaniela Marques, Rafael Carecho, Diogo Carregosa and Cláudia Nunes dos Santos\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction - Neurodegenerative disorders, dietary (poly)phenols and neuroinflammation\u003c\/p\u003e \u003cp\u003e4.2 (Poly)phenols metabolism and distribution\u003c\/p\u003e \u003cp\u003e4.3 (Poly)phenol metabolites and their brain permeability\u003c\/p\u003e \u003cp\u003e4.4 LMW (poly)phenols metabolites as effectors for attenuating neuroinflammation\u003c\/p\u003e \u003cp\u003e4.5 Concluding remarks\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Deciphering Complex Natural Mixtures through Metabolome Mining of Mass Spectrometry Data: the Plant Specialized Metabolome as a Case Study\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eJustin J.J. van der Hooft, Madeleine Ernst, Daniel Papenberg, Kyo Bin Kang, Iris F. Kappers, Marnix H. Medema, Pieter C. Dorrestein, and Simon Rogers\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5.1 Introduction\u003c\/p\u003e \u003cp\u003e5.2 Materials and methods\u003c\/p\u003e \u003cp\u003e5.3 Results and discussion\u003c\/p\u003e \u003cp\u003e5.4 Current limitations\u003c\/p\u003e \u003cp\u003e5.5 Conclusions\u003c\/p\u003e \u003cp\u003e5.6 Outlook\u003c\/p\u003e \u003cp\u003e5.7 Acknowledgements\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Application of MS-based Metabolomics to Investigate Biomarkers of Apple Consumption Resulting from Microbiota and Host Metabolism Interactions\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eFulvio Mattivi and Maria M. Ulaszewska\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction\u003c\/p\u003e \u003cp\u003e6.2 Materials and methods\u003c\/p\u003e \u003cp\u003e6.3 Results and discussion\u003c\/p\u003e \u003cp\u003e6.4 Conclusions\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Non-extractable polyphenols should be systematically included in polyphenols analysis\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eEnrique Báez-García, Sonia G. Sáyago-Ayerdi and Jara Pérez-Jiménez\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7.1 Introduction: the concept of non-extractable polyphenols\u003c\/p\u003e \u003cp\u003e7.2 Analysis of non-extractable polyphenols\u003c\/p\u003e \u003cp\u003e7.3 Why should non-extractable polyphenols be systematically included in polyphenol analysis?\u003c\/p\u003e \u003cp\u003e7.4 Relevance of the determination of non-extractable polyphenols in quality control\u003c\/p\u003e \u003cp\u003e7.5. Perspectives\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Template-mediated engineering of functional metal--phenolic complex coatings\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eSteve Spoljaric, J.J. Richardson, Yi Ju, Frank Caruso\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8.1 Introduction\u003c\/p\u003e \u003cp\u003e8.2 Template-mediated techniques to deposit MPNs\u003c\/p\u003e \u003cp\u003e8.3 MPN film properties\u003c\/p\u003e \u003cp\u003e8.4 MPN surface interactions and applications\u003c\/p\u003e \u003cp\u003e8.5 Upscaling considerations and challenges\u003c\/p\u003e \u003cp\u003e8.6 Method automation: possibilities and outlook\u003c\/p\u003e \u003cp\u003e8.7 Conclusions\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Highly Efficient Production of Dihydroflavonol 4-Reductases in Tobacco Cells and Refinement of the BuOH-HCl Enzymatic Assay\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eLingping Zhu, Saku Mattila, Roosa Matomäki, Lorenzo Mollo, Sharmin Ahamed, Sara M. Abdou, Hany Bashandy and Teemu H. Teeri\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9.1 Introduction\u003c\/p\u003e \u003cp\u003e9.2 Results\u003c\/p\u003e \u003cp\u003e9.3 Materials and methods\u003c\/p\u003e \u003cp\u003e9.4 Discussion\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 A long and winding road: the evolution of transcriptional regulation of polyphenol biosynthesis\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eCathie Martin, Jie Li and Nick W. Albert\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10.1 Introduction\u003c\/p\u003e \u003cp\u003e10.2 The importance of R2R3Myb transcription factors (TFs) in the regulation of phenylpropanoid metabolism in plants\u003c\/p\u003e \u003cp\u003e10.3 The role of bHLH proteins in the regulation of phenylpropanoid metabolism\u003c\/p\u003e \u003cp\u003e10.4 The role of the WDR in the MBW complex in the regulation of polyphenol metabolism\u003c\/p\u003e \u003cp\u003e10.5 Additional factors regulating transcriptional control of the MBW complex\u003c\/p\u003e \u003cp\u003e10.6 Conclusions\u003c\/p\u003e \u003cp\u003e10.7 Acknowledgements\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Analysis of Proanthocyanidins in Food Ingredients by the 4-(Dimethylamino)cinnamaldehyde Reaction\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eDaniel Esquivel-Alvarado, Emilia Alfaro-Viquez, Andrew Birmingham, Abigail Kramschuster, Christian G. Krueger, and Jess D. Reed\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11.1. Introduction\u003c\/p\u003e \u003cp\u003e11.2. Background on the 4-(dimethylamino)cinnalmaldehyde (DMAC) reaction with PACs\u003c\/p\u003e \u003cp\u003e11.3. Mechanism of the acid catalyzed DMAC reaction with PACs\u003c\/p\u003e \u003cp\u003e11.4 Absorption and emission spectra of the DMAC reaction products\u003c\/p\u003e \u003cp\u003e11.5 Standards for the DMAC reaction and accuracy of the method\u003c\/p\u003e \u003cp\u003e11.6 Interaction of PAC-DMAC reaction products with Extra-Intestinal Pathogenic Escherichia coli\u003c\/p\u003e \u003cp\u003e11.7 Conclusions\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Reactions of Ellagitannins Related to their Metabolism in Higher Plants\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eTakashi Tanaka\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12.1 Introduction\u003c\/p\u003e \u003cp\u003e12.2 Structural variety of ellagitannin acyl groups\u003c\/p\u003e \u003cp\u003e12.3 Reactions of the DHHDP group\u003c\/p\u003e \u003cp\u003e12.4 Decomposition of 1,4-DHHDP-α-D-glucose\u003c\/p\u003e \u003cp\u003e12.5 Amariin as a precursor of geraniin\u003c\/p\u003e \u003cp\u003e12.6 Triterpene HHDP esters in Castanopsis sieboldii\u003c\/p\u003e \u003cp\u003e12.7 Highly-oxidized ellagitannins in Carpinus japonica\u003c\/p\u003e \u003cp\u003e12.8 Similarity of catechin oxidation to oxidation of methyl gallate\u003c\/p\u003e \u003cp\u003e12.9 Production mechanism of DHHDP and HHDP\u003c\/p\u003e \u003cp\u003e12.10 Oxidative degradation of ellagitannins\u003c\/p\u003e \u003cp\u003e12.11 Conclusions\u003c\/p\u003e \u003cp\u003eReferences\u003c\/p\u003e \u003cp\u003eIndex\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eJuha-Pekka Salminen\u003c\/b\u003e, current Communication Manager of Groupe Polyphénols (board member since 2018), is Full Professor of Natural Compound Chemistry at the University of Turku, Finland. His research group specializes in analytical chemistry, chemical ecology and bioactivity studies of large polyphenols, with a focus on ellagitannins and proanthocyanidins and their distribution and significance in the plant kingdom. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eKristiina Wähälä\u003c\/b\u003e, current Vice-President of the Groupe Polyphénols (2012–2014, 2018–2020) is Professor of Organic Chemistry at the University of Helsinki, Finland. Her research is focused on synthesis, analysis, and isotopical labelling of plant polyphenols and their metabolites in humans in connection with drug discovery and binding studies to target enzymes. The focus on her chemical synthesis is on environmentally benign methods, green chemistry and biomass utilization. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eVictor de Freitas\u003c\/b\u003e, former President of the Groupe Polyphénols (2016–2021), is Full Professor at the Faculty of Sciences of the University of Porto, Portugal. His research on polyphenols include: structural characterization, chemical transformations in plants and foods during harvest and storage, influence on the sensory properties of foods (color, astringency and bitterness), and other biological properties. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eStéphane Quideau\u003c\/b\u003e, former President of the Groupe Polyphénols (2008–2012), is Full Professor of Organic and Bioorganic Chemistry at the University of Bordeaux, France, and Senior Member of the “Institut Universitaire de France.” His laboratory is involved in research on plant polyphenol chemistry and chemical biology, with particular interests in ellagitannin chemical reactivity and synthesis, and in polyphenol–protein interactions.  \u003c\/p\u003e\u003cp\u003ePlant polyphenols are specialized metabolites that constitute one of the most common and widespread groups of natural products. They are essential plant components for adaptation to the environment and possess a large and diverse range of biological functions that provide many benefits to both plants and humans. Polyphenols, from their structurally simplest forms to their oligo\/polymeric versions (i.e. tannins and lignins), are phytoestrogens, plant pigments, antioxidants, and structural components of the plant cell wall. The interactions between tannins and proteins are involved in plant defense against predation, cause astringency in foods and beverages, and affect the nutritional and health properties of human and animal food plants.\u003c\/p\u003e \u003cp\u003eThis eighth volume of the highly regarded \u003ci\u003eRecent Advances in Polyphenol Research\u003c\/i\u003e series is edited by Juha-Pekka Salminen, Kristiina Wähälä, Victor de Freitas, and Stéphane Quideau, and brings together chapters written by some of the leading experts working in the polyphenol sciences today. Topics covered include:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eStructure, reactivity and synthesis\u003c\/li\u003e \u003cli\u003eBioactivity and bioavailability\u003c\/li\u003e \u003cli\u003eMetabolomics, targeted analysis and big data\u003c\/li\u003e \u003cli\u003eQuality control \u0026amp; standardization\u003c\/li\u003e \u003cli\u003eBiogenesis and functions in plants and ecosystems\u003c\/li\u003e \u003cli\u003eBiomaterials \u0026amp; applied sciences\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eDistilling the most recent and illuminating data available, this new volume is an invaluable resource for chemists, biochemists, plant scientists, pharmacognosists and pharmacologists, biologists, ecologists, food scientists and nutritionists.\u003c\/p\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47989924593893,"sku":"NP9781119844761","price":200.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781119844761.jpg?v=1761785927","url":"https:\/\/k12savings.com\/products\/recent-advances-in-polyphenol-research-volume-8-isbn-9781119844761","provider":"K12savings","version":"1.0","type":"link"}