{"product_id":"proteomic-applications-in-cancer-detection-and-discovery-isbn-9780471724063","title":"Proteomic Applications in Cancer Detection and Discovery","description":"\u003cp\u003e\u003cb\u003eHelps researchers in proteomics and oncology work together to understand, prevent, and cure cancer\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eProteomic data is increasingly important to understanding the origin and progression of cancer; however, most oncologic researchers who depend on proteomics for their studies do not collect the data themselves. As a result, there is a knowledge gap between scientists, who devise proteomic techniques and collect the data, and the oncologic researchers, who are expected to interpret and apply proteomic data. Bridging the gap between proteomics and oncology research, this book explains how proteomic technology can be used to address some of the most important questions in cancer research.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eProteomic Applications in Cancer Detection and Discovery\u003c\/i\u003e enables readers to understand how proteomic data is acquired and analyzed and how it is interpreted. Author Timothy Veenstra has filled the book with examples—many based on his own firsthand research experience—that clearly demonstrate the application of proteomic technology in oncology research, including the discovery of novel biomarkers for different types of cancers.\u003c\/p\u003e \u003cp\u003eThe book begins with a brief introduction to systems biology, explaining why cancer is a systems biology disease. Next, it covers such topics as:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eMass spectrometry in cancer research\u003c\/li\u003e \u003cli\u003eApplication of proteomics to global phosphorylation analysis\u003c\/li\u003e \u003cli\u003eSearch for biomarkers in biofluids\u003c\/li\u003e \u003cli\u003eRise and fall of proteomic patterns for cancer diagnostics\u003c\/li\u003e \u003cli\u003eEmergence of protein arrays\u003c\/li\u003e \u003cli\u003eRole of proteomics in personalized medicine\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThe final chapter is dedicated to the future prospects of proteomics in cancer research.\u003c\/p\u003e \u003cp\u003eBy guiding readers through the latest proteomic technologies and their applications in cancer research, \u003ci\u003eProteomic Applications in Cancer Detection and Discovery\u003c\/i\u003e enhances the ability of researchers in proteomics and researchers in oncology to collaborate in order to better understand cancer and develop strategies to prevent and treat it.\u003c\/p\u003e \u003cp\u003ePreface vii\u003c\/p\u003e \u003cp\u003eAcknowledgments ix\u003c\/p\u003e \u003cp\u003e1 Systems Biology 1\u003c\/p\u003e \u003cp\u003e2 Mass Spectrometry in Cancer Research 27\u003c\/p\u003e \u003cp\u003e3 Quantitative Proteomics 59\u003c\/p\u003e \u003cp\u003e4 Proteomic Analysis of Posttranslational Modifications 87\u003c\/p\u003e \u003cp\u003e5 Characterization of Protein Complexes 117\u003c\/p\u003e \u003cp\u003e6 Global Phosphorylation Analysis 145\u003c\/p\u003e \u003cp\u003e7 the Search for Biomarkers in Biofluids 171\u003c\/p\u003e \u003cp\u003e8 Proteomic Patterns: a New Paradigm in Diagnostics And Therapeutics? 195\u003c\/p\u003e \u003cp\u003e9 the Emergence of Protein Arrays 215\u003c\/p\u003e \u003cp\u003e10 the Role of Proteomics in Personalized Medicine 241\u003c\/p\u003e \u003cp\u003e11 the Critical Role of Bioinformatics 263\u003c\/p\u003e \u003cp\u003e12 Future Prospects of Proteomics in Cancer Research 281\u003c\/p\u003e \u003cp\u003eIndex 305\u003c\/p\u003e  \u003cp\u003e“By guiding readers through the latest proteomic technologies and their applications in cancer research, “Proteomic Applications in Cancer Detection and Discovery\" enhances the ability of researchers in proteomics and researchers in oncology to collaborate in order to better understand cancer and develop strategies to prevent and treat it.”  (\u003ci\u003eNewbooks.lib\u003c\/i\u003e, 11 September 2014\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eTIMOTHY D. VEENSTRA, PhD,\u003c\/b\u003e is Director of the Laboratory of Proteomics and Analytical Technologies at the Frederick National Laboratory for Cancer Research. Dr. Veenstra and his lab group develop and apply chromatography and mass spectrometry approaches to characterize protein complexes and the role of post-translational modifications in these complexes. Additionally, they use high-throughput proteomic approaches for the discovery of biomarkers for disease as well as proteomic and metabolomic technology for the interrogation of clinical samples. Dr. Veenstra has coauthored more than 300 peer-reviewed publications and is the coeditor of \u003ci\u003eProteomics for Biological Discovery.\u003c\/i\u003e\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eHelps researchers in proteomics and oncology work together to understand, prevent, and cure cancer\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eProteomic data is increasingly important to understanding the origin and progression of cancer; however, most oncologic researchers who depend on proteomics for their studies do not collect the data themselves. As a result, there is a knowledge gap between scientists, who devise proteomic techniques and collect the data, and the oncologic researchers, who are expected to interpret and apply proteomic data. Bridging the gap between proteomics and oncology research, this book explains how proteomic technology can be used to address some of the most important questions in cancer research.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eProteomic Applications in Cancer Detection and Discovery\u003c\/i\u003e enables readers to understand how proteomic data is acquired and analyzed and how it is interpreted. Author Timothy Veenstra has filled the book with examples—many based on his own firsthand research experience—that clearly demonstrate the application of proteomic technology in oncology research, including the discovery of novel biomarkers for different types of cancers.\u003c\/p\u003e \u003cp\u003eThe book begins with a brief introduction to systems biology, explaining why cancer is a systems biology disease. Next, it covers such topics as:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eMass spectrometry in cancer research\u003c\/li\u003e \u003cli\u003eApplication of proteomics to global phosphorylation analysis\u003c\/li\u003e \u003cli\u003eSearch for biomarkers in biofluids\u003c\/li\u003e \u003cli\u003eRise and fall of proteomic patterns for cancer diagnostics\u003c\/li\u003e \u003cli\u003eEmergence of protein arrays\u003c\/li\u003e \u003cli\u003eRole of proteomics in personalized medicine\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThe final chapter is dedicated to the future prospects of proteomics in cancer research.\u003c\/p\u003e \u003cp\u003eBy guiding readers through the latest proteomic technologies and their applications in cancer research, \u003ci\u003eProteomic Applications in Cancer Detection and Discovery\u003c\/i\u003e enhances the ability of researchers in proteomics and researchers in oncology to collaborate in order to better understand cancer and develop strategies to prevent and treat it.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989880914149,"sku":"NP9780471724063","price":101.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780471724063.jpg?v=1761785774","url":"https:\/\/k12savings.com\/products\/proteomic-applications-in-cancer-detection-and-discovery-isbn-9780471724063","provider":"K12savings","version":"1.0","type":"link"}