{"product_id":"protein-secretion-in-bacteria-isbn-9781683670278","title":"Protein Secretion in Bacteria","description":"\u003cp\u003eProtein transport into and across membranes is a fundamental process in bacteria that touches upon and unites many areas of microbiology, including bacterial cell physiology, adhesion and motility, nutrient scavenging, intrabacterial signaling and social behavior, toxin deployment, interbacterial antagonism and collaboration, host invasion and disruption, and immune evasion. A broad repertoire of mechanisms and macromolecular machines are required to deliver protein substrates across bacterial cell membranes for intended effects. Some machines are common to most, if not all bacteria, whereas others are specific to Gram-negative or Gram-positive species or species with unique cell envelope properties such as members of Actinobacteria and Spirochetes.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eProtein Secretion in Bacteria\u003c\/i\u003e, authored and edited by an international team of experts, draws together the many distinct functions and mechanisms involved in protein translocation in one concise tome. This comprehensive book presents updated information on all aspects of bacterial protein secretion encompassing:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eIndividual secretory systems–Sec, Tat, and T1SS through the newly discovered T9SS\u003c\/li\u003e \u003cli\u003eMechanisms, structures, and functions of bacterial secretion systems\u003c\/li\u003e \u003cli\u003eLipoprotein sorting pathways, outer membrane vesicles, and the sortase system\u003c\/li\u003e \u003cli\u003eStructures and roles of surface organelles, including flagella, pili, and curli\u003c\/li\u003e \u003cli\u003eEmerging technologies and translational implications\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eProtein Secretion in Bacteria\u003c\/i\u003e serves as both an introductory guide for students and postdocs and a ready reference for seasoned researchers whose work touches on protein export and secretion. This volume synthesizes the diversity of mechanisms of bacterial secretion across the microbial world into a digestible resource to stimulate new research, inspire continued identification and characterization of novel systems, and bring about new ways to manipulate these systems for biotechnological, preventative, and therapeutic applications.\u003c\/p\u003e \u003cp\u003eForeword\u003c\/p\u003e \u003cp\u003ePreface\u003c\/p\u003e \u003cp\u003eContributors\u003c\/p\u003e \u003cp\u003e1 Electron Cryotomography of Bacterial Secretion Systems\u003cbr\u003e\u003ci\u003eCatherine M. Oikonomou and Grant J. Jensen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 SecA-Mediated Protein Translocation through the SecYEG Channel\u003cbr\u003e\u003ci\u003eAmalina Ghaisani Komarudin and Arnold J.M. Driessen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 The Two Distinct Types of SecA2-Dependent Export Systems\u003cbr\u003e\u003ci\u003eMiriam Braunstein, Barbara A. Bensing, and Paul M. Sullam\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 The Conserved Role of YidC in Membrane Protein Biogenesis\u003cbr\u003e\u003ci\u003eSri Karthika Shanmugam and Ross E. Dalbey\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 The Twin-Arginine Pathway for Protein Secretion\u003cbr\u003e\u003ci\u003eKelly M. Frain, Jan Maarten van Dijl, and Colin Robinson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Lipoproteins and Their Trafficking to The Outer Membrane\u003cbr\u003e\u003ci\u003eMarcin Grabowicz\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Protein Secretion in Spirochetes\u003cbr\u003e\u003ci\u003eWolfram R. Zückert\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Outer Membrane Protein Insertion by the β-barrel Assembly Machine\u003cbr\u003e\u003ci\u003eDante P. Ricci and Thomas J. Silhavy\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 The TAM: A Translocation and Assembly Module of the β-barrel Assembly Machinery in Bacterial Outer Membranes\u003cbr\u003e\u003ci\u003eChristopher J. Stubenrauch and Trevor Lithgow\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 The Dynamic Structures of the Type IV Pilus\u003cbr\u003e\u003ci\u003eMatthew McCallum, Lori L. Burrows, and P. Lynne Howell\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Gram-Positive Type IV Pili and Competence\u003cbr\u003e\u003ci\u003eSandra Muschiol, Marie-Stephanie Aschtgen, Priyanka Nannapaneni, and Birgitta Henriques-Normark\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 The Remarkable Biomechanical Properties of the Type 1 Chaperone-Usher Pilus: A Structural and Molecular Perspective\u003cbr\u003e\u003ci\u003eManuela K. Hospenthal and Gabriel Waksman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Therapeutic Approaches Targeting the Assembly and Function of Chaperone-Usher Pili\u003cbr\u003e\u003ci\u003eJohn J. Psonis and David G. Thanassi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 Curli Biogenesis: Bacterial Amyloid Assembly by the Type VIII Secretion Pathway\u003cbr\u003e\u003ci\u003eSujeet Bhoite, Nani van Gerven, Matthew R. Chapman, and Han Remaut\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Sortases, Surface Proteins, and Their Roles in Staphylococcus aureus Disease and Vaccine Development\u003cbr\u003e\u003ci\u003eOlaf Schneewind and Dominique Missiakas\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16 Architecture and Assembly of Periplasmic Flagellum\u003cbr\u003e\u003ci\u003eYunjie Chang and Jun Liu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17 Outer Membrane Vesicle-Host Cell Interactions\u003cbr\u003e\u003ci\u003eJessica D. Cecil, Natalie Sirisaengtaksin, Neil M. O’Brien-Simpson, and Anne Marie Krachler\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18 Type I Secretion Systems—One Mechanism for All?\u003cbr\u003e\u003ci\u003eOlivia Spitz, Isabelle N. Erenburg, Tobias Beer, Kerstin Kanonenberg, I. Barry Holland, and Lutz\u003c\/i\u003e \u003ci\u003eSchmitt\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e19 Architecture, Function, and Substrates of the Type II Secretion System\u003cbr\u003e\u003ci\u003eKonstantin V. Korotkov and Maria Sandkvist\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e20 The Injectisome, A Complex Nanomachine for Protein Injection into Mammalian Cells\u003cbr\u003e\u003ci\u003eMaria Lara-Tejero and Jorge E. Galán\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e21 Promises and Challenges of the Type Three Secretion System Injectisome as an Antivirulence Target\u003cbr\u003e\u003ci\u003eAlyssa C. Fasciano, Lamyaa Shaban, and Joan Mecsas\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e22 Biological and Structural Diversity of Type IV Secretion Systems\u003cbr\u003e\u003ci\u003eYang Grace Li, Bo Hu, and Peter J. Christie\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e23 Hostile Takeover: Hijacking of Endoplasmic Reticulum Function by T4SS and T3SS Effectors Creates a Niche for Intracellular Pathogens\u003cbr\u003e\u003ci\u003eApril Y. Tsai, Bevin C. English, and Renée M. Tsolis\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e24 Type V Secretion in Gram-Negative Bacteria\u003cbr\u003e\u003ci\u003eHarris D. Bernstein\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e25 Bordetella Filamentous Hemagglutinin, A Model for the Two-Partner Secretion Pathway\u003cbr\u003e\u003ci\u003eZachary M. Nash and Peggy A. Cotter\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e26 Structure and Activity of the Type VI Secretion System\u003cbr\u003e\u003ci\u003eYassine Cherrak, Nicolas Flaugnatti, Eric Durand, Laure Journet, and Eric Cascales\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e27 Type VI Secretion Systems and the Gut Microbiota\u003cbr\u003e\u003ci\u003eMichael J. Coyne and Laurie E. Comstock\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e28 ESX \/ Type VII Secretion Systems–An Important Way Out for Mycobacterial Proteins\u003cbr\u003e\u003ci\u003eFarzam Vaziri and Roland Brosch\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e29 Bacteroidetes Gliding Motility and the Type IX Secretion System\u003cbr\u003e\u003ci\u003eMark J. McBride\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e30 Similarities and Differences between Colicin and Filamentous Phage Uptake by Bacterial Cells\u003cbr\u003e\u003ci\u003eDenis Duché and Laetitia Houot\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e31 A Hybrid Secretion System Facilitates Bacterial Sporulation: A Structural Perspective\u003cbr\u003e\u003ci\u003eNatalie Zeytuni and Natalie C.J. Strynadka\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex\u003c\/p\u003e \u003cp\u003e“\u003ci\u003eProtein Secretion in Bacteria\u003c\/i\u003e is a timely and phenomenal contribution to the scientific literature by a superb group of experts who have a great perspective on this fascinating topic. This volume is an important addition to the library of all scholars interested in microbial cell and molecular biology, dynamic nanomachines, and pathogenesis.  Enjoy the read!” —\u003cb\u003e\u003ci\u003eJohn J. Mekalanos\u003c\/i\u003e\u003c\/b\u003e\u003ci\u003e, PhD, Harvard Medical School\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eMaria Sandkvist\u003c\/b\u003e, Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eEric Cascales\u003c\/b\u003e, CNRS Aix-Marseille Université, Mediterranean Institute of Microbiology, Marseille, France.\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePeter J. Christie\u003c\/b\u003e, Department of Microbiology and Molecular Genetics, McGovern Medical School, Houston, Texas.\u003c\/p\u003e  \u003cp\u003eProtein transport into and across membranes is a fundamental process in bacteria that touches upon and unites many areas of microbiology, including bacterial cell physiology, adhesion and motility, nutrient scavenging, intrabacterial signaling and social behavior, toxin deployment, interbacterial antagonism and collaboration, host invasion and disruption, and immune evasion. A broad repertoire of mechanisms and macromolecular machines are required to deliver protein substrates across bacterial cell membranes for intended effects. Some machines are common to most, if not all bacteria, whereas others are specific to Gram-negative or Gram-positive species or species with unique cell envelope properties such as members of Actinobacteria and Spirochetes.  \u003c\/p\u003e\u003cp\u003eProtein Secretion in Bacteria, authored and edited by an international team of experts, draws together the many distinct functions and mechanisms involved in protein translocation in one concise tome. This comprehensive book presents updated information on all aspects of bacterial protein secretion encompassing:  \u003c\/p\u003e\u003cul\u003e \u003cli\u003eIndividual secretory systems–Sec, Tat, and T1SS through the newly discovered T9SS\u003c\/li\u003e \u003cli\u003eMechanisms, structures, and functions of bacterial secretion systems\u003c\/li\u003e \u003cli\u003eLipoprotein sorting pathways, outer membrane vesicles, and the sortase system\u003c\/li\u003e \u003cli\u003eStructures and roles of surface organelles, including flagella, pili, and curli\u003c\/li\u003e \u003cli\u003eEmerging technologies and translational implications\u003c\/li\u003e \u003c\/ul\u003e  \u003cp\u003eProtein Secretion in Bacteria serves as both an introductory guide for students and postdocs and a ready reference for seasoned researchers whose work touches on protein export and secretion. This volume synthesizes the diversity of mechanisms of bacterial secretion across the microbial world into a digestible resource to stimulate new research, inspire continued identification and characterization of novel systems, and bring about new ways to manipulate these systems for biotechnological, preventative, and therapeutic applications.\u003c\/p\u003e","brand":"ASM Press","offers":[{"title":"Default Title","offer_id":47989880652005,"sku":"NP9781683670278","price":154.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781683670278.jpg?v=1761785773","url":"https:\/\/k12savings.com\/products\/protein-secretion-in-bacteria-isbn-9781683670278","provider":"K12savings","version":"1.0","type":"link"}