{"product_id":"practical-flow-cytometry-in-haematology-isbn-9781118747032","title":"Practical Flow Cytometry in Haematology","description":"\u003cp\u003eThe analysis of blood, bone marrow and tissue fluid specimens requires a multi-faceted approach with the integration of scientific data from a number of disciplines. No single discipline can operate in isolation or errors will occur. Flow cytometry is in a privileged position in that it can provide rapid analysis of specimens and it is often the first definitive investigation to produce results and help formulate a working diagnosis.\u003c\/p\u003e \u003cp\u003eThis companion text to \u003ci\u003ePractical Flow Cytometry in Haematology Diagnosis \u003c\/i\u003econtains 100 worked examples drawn from real clinical cases presenting to the authors’ institution. Cases are illustrated with peripheral blood and bone marrow cytology, tissue pathology and cytogenetic and molecular data, which are integrated to generate, where appropriate, a diagnosis based on the \u003ci\u003eWHO Classification of Tumours of Haematopoietic and Lymphoid Tissues\u003c\/i\u003e. The spectrum of clinical cases includes adult and paediatric patients, and both neoplastic and reactive disorders. The cases appear in no particular order to challenge the reader to make their own diagnosis.\u003c\/p\u003e \u003cp\u003eThe reader will review May−Grünwald−Giemsa (MGG)-stained films of peripheral blood and bone marrow aspirates presented alongside flow cytometric data and haematoxylin and eosin (H\u0026amp;E)-stained bone marrow and other tissue biopsy sections. Immunohistochemistry is used to further clarify the tissue lineage and cell differentiation. Cytogenetic studies using metaphase preparations are used to identify translocations and chromosome gains and losses whilst interphase fluorescence \u003ci\u003ein situ\u003c\/i\u003e hybridisation (FISH) studies and polymerase chain reaction (PCR) are used to identify gene fusions, gene rearrangements and deletions. Each case concludes with a discussion of the features that are important to making a diagnosis. The cases are also listed according to disease classification in the appendix so that the text can also be used as a reference.\u003c\/p\u003e \u003cp\u003e\u003ci\u003ePractical Flow Cytometry in Haematology: 100 Worked Examples\u003c\/i\u003e:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eProvides a practical, example-based resource for flow cytometry\u003c\/li\u003e \u003cli\u003eDemonstrates how flow cytometry results should be interpreted and applied to optimize patient care\u003c\/li\u003e \u003cli\u003eIncludes both malignant and benign conditions\u003c\/li\u003e \u003cli\u003eCan be used in conjunction with \u003ci\u003ePractical Flow Cytometry in Haematology Diagnosis\u003c\/i\u003e, by the same author team (ISBN 9780470671207)\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003ePractical Flow Cytometry in Haematology: 100 Worked Examples\u003c\/i\u003e is ideal for practicing haematologists and histopathologists with an interest in haematopathology, but particularly directed at trainee haematologists and scientists preparing for FRCPath and related examinations.\u003c\/p\u003eDieses Begleitbuch zu Practical Flow Cytometry in Haematology Diagnosis enthält 100 Beispiele klinischer Fälle, aus dem Alltag des Autors. Die einzelnen Fallbeispiele werden durch Daten aus den Bereichen periphäre Blut- und Knochenmarkzytologie, Gewebepathologie, Zytogenetik und Molekulardiagnostik ergänzt, die im Einzelfall eine Diagnose anhand der Tumorklassifikation der WHO bei hämotopoetischem und lymphoidem Gewebe ermöglichen.\u003cbr\u003e \u003cbr\u003e - Referenzwerk zur Durchflusszytometrie, das die Methode anhand von Beispielen aus der Praxis erläutert.\u003cbr\u003e - Bietet Übungen zur Überprüfung des Lernstatus und bereitet auf das FRCPath-Examen vor.\u003cbr\u003e - Zeigt, wie Ergebnisse der Durchflusszytometrie interpretiert und anwendet werden, um die Behandlung der Patienten zu unterstützen.\u003cbr\u003e - Behandelt sowohl krankhafte als auch normale Befunde.\u003cbr\u003e - Begleitbuch zu Practical Flow Cytometry in Haematology Diagnosis des Autors (ISBN 978-0-470-67120-7).\u003cbr\u003e \u003cp\u003ePreface, vii\u003c\/p\u003e \u003cp\u003eAcknowledgement, ix\u003c\/p\u003e \u003cp\u003eList of Abbreviations, xi\u003c\/p\u003e \u003cp\u003eTechnical Notes, xv\u003c\/p\u003e \u003cp\u003eLaboratory Values, xix\u003c\/p\u003e \u003cp\u003eCase 1 1\u003c\/p\u003e \u003cp\u003eCase 2 6\u003c\/p\u003e \u003cp\u003eCase 3 11\u003c\/p\u003e \u003cp\u003eCase 4 15\u003c\/p\u003e \u003cp\u003eCase 5 18\u003c\/p\u003e \u003cp\u003eCase 6 21\u003c\/p\u003e \u003cp\u003eCase 7 24\u003c\/p\u003e \u003cp\u003eCase 8 27\u003c\/p\u003e \u003cp\u003eCase 9 31\u003c\/p\u003e \u003cp\u003eCase 10 35\u003c\/p\u003e \u003cp\u003eCase 11 39\u003c\/p\u003e \u003cp\u003eCase 12 43\u003c\/p\u003e \u003cp\u003eCase 13 46\u003c\/p\u003e \u003cp\u003eCase 14 50\u003c\/p\u003e \u003cp\u003eCase 15 54\u003c\/p\u003e \u003cp\u003eCase 16 59\u003c\/p\u003e \u003cp\u003eCase 17 62\u003c\/p\u003e \u003cp\u003eCase 18 65\u003c\/p\u003e \u003cp\u003eCase 19 68\u003c\/p\u003e \u003cp\u003eCase 20 70\u003c\/p\u003e \u003cp\u003eCase 21 74\u003c\/p\u003e \u003cp\u003eCase 22 77\u003c\/p\u003e \u003cp\u003eCase 23 80\u003c\/p\u003e \u003cp\u003eCase 24 82\u003c\/p\u003e \u003cp\u003eCase 25 87\u003c\/p\u003e \u003cp\u003eCase 26 90\u003c\/p\u003e \u003cp\u003eCase 27 93\u003c\/p\u003e \u003cp\u003eCase 28 95\u003c\/p\u003e \u003cp\u003eCase 29 100\u003c\/p\u003e \u003cp\u003eCase 30 104\u003c\/p\u003e \u003cp\u003eCase 31 106\u003c\/p\u003e \u003cp\u003eCase 32 110\u003c\/p\u003e \u003cp\u003eCase 33 114\u003c\/p\u003e \u003cp\u003eCase 34 117\u003c\/p\u003e \u003cp\u003eCase 35 122\u003c\/p\u003e \u003cp\u003eCase 36 126\u003c\/p\u003e \u003cp\u003eCase 37 129\u003c\/p\u003e \u003cp\u003eCase 38 132\u003c\/p\u003e \u003cp\u003eCase 39 136\u003c\/p\u003e \u003cp\u003eCase 40 140\u003c\/p\u003e \u003cp\u003eCase 41 143\u003c\/p\u003e \u003cp\u003eCase 42 146\u003c\/p\u003e \u003cp\u003eCase 43 151\u003c\/p\u003e \u003cp\u003eCase 44 154\u003c\/p\u003e \u003cp\u003eCase 45 159\u003c\/p\u003e \u003cp\u003eCase 46 163\u003c\/p\u003e \u003cp\u003eCase 47 166\u003c\/p\u003e \u003cp\u003eCase 48 168\u003c\/p\u003e \u003cp\u003eCase 49 172\u003c\/p\u003e \u003cp\u003eCase 50 177\u003c\/p\u003e \u003cp\u003eCase 51 180\u003c\/p\u003e \u003cp\u003eCase 52 183\u003c\/p\u003e \u003cp\u003eCase 53 186\u003c\/p\u003e \u003cp\u003eCase 54 189\u003c\/p\u003e \u003cp\u003eCase 55 193\u003c\/p\u003e \u003cp\u003eCase 56 196\u003c\/p\u003e \u003cp\u003eCase 57 201\u003c\/p\u003e \u003cp\u003eCase 58 206\u003c\/p\u003e \u003cp\u003eCase 59 210\u003c\/p\u003e \u003cp\u003eCase 60 213\u003c\/p\u003e \u003cp\u003eCase 61 216\u003c\/p\u003e \u003cp\u003eCase 62 218\u003c\/p\u003e \u003cp\u003eCase 63 224\u003c\/p\u003e \u003cp\u003eCase 64 227\u003c\/p\u003e \u003cp\u003eCase 65 232\u003c\/p\u003e \u003cp\u003eCase 66 236\u003c\/p\u003e \u003cp\u003eCase 67 240\u003c\/p\u003e \u003cp\u003eCase 68 244\u003c\/p\u003e \u003cp\u003eCase 69 249\u003c\/p\u003e \u003cp\u003eCase 70 253\u003c\/p\u003e \u003cp\u003eCase 71 256\u003c\/p\u003e \u003cp\u003eCase 72 260\u003c\/p\u003e \u003cp\u003eCase 73 266\u003c\/p\u003e \u003cp\u003eCase 74 269\u003c\/p\u003e \u003cp\u003eCase 75 274\u003c\/p\u003e \u003cp\u003eCase 76 276\u003c\/p\u003e \u003cp\u003eCase 77 281\u003c\/p\u003e \u003cp\u003eCase 78 284\u003c\/p\u003e \u003cp\u003eCase 79 289\u003c\/p\u003e \u003cp\u003eCase 80 292\u003c\/p\u003e \u003cp\u003eCase 81 297\u003c\/p\u003e \u003cp\u003eCase 82 300\u003c\/p\u003e \u003cp\u003eCase 83 306\u003c\/p\u003e \u003cp\u003eCase 84 310\u003c\/p\u003e \u003cp\u003eCase 85 315\u003c\/p\u003e \u003cp\u003eCase 86 319\u003c\/p\u003e \u003cp\u003eCase 87 321\u003c\/p\u003e \u003cp\u003eCase 88 325\u003c\/p\u003e \u003cp\u003eCase 89 327\u003c\/p\u003e \u003cp\u003eCase 90 330\u003c\/p\u003e \u003cp\u003eCase 91 334\u003c\/p\u003e \u003cp\u003eCase 92 338\u003c\/p\u003e \u003cp\u003eCase 93 342\u003c\/p\u003e \u003cp\u003eCase 94 347\u003c\/p\u003e \u003cp\u003eCase 95 351\u003c\/p\u003e \u003cp\u003eCase 96 355\u003c\/p\u003e \u003cp\u003eCase 97 359\u003c\/p\u003e \u003cp\u003eCase 98 365\u003c\/p\u003e \u003cp\u003eCase 99 370\u003c\/p\u003e \u003cp\u003eCase 100 375\u003c\/p\u003e \u003cp\u003eAntibodies Used in Immunohistochemistry Studies, 381\u003c\/p\u003e \u003cp\u003eFlow Cytometry Antibodies, 386\u003c\/p\u003e \u003cp\u003eMolecular Terminology, 389\u003c\/p\u003e \u003cp\u003eClassification of Cases According to Diagnosis, 390\u003c\/p\u003e \u003cp\u003eIndex, 391\u003c\/p\u003e \u003cp\u003e\u003cb\u003eMike Leach\u003c\/b\u003e FRCP, FRCPath\u003cbr\u003eConsultant Haematologist and Honorary Senior Lecturer, Haematology Laboratories and West of Scotland Cancer Centre Gartnavel General Hospital, Glasgow, UK.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eMark Drummond\u003c\/b\u003e PhD, FRCPath Consultant Haematologist and Honorary Senior Lecturer, Haematology Laboratories and West of Scotland Cancer Centre Gartnavel General Hospital, Glasgow, UK.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eAllyson Doig\u003c\/b\u003e MSc, FIBMS Haemato-Oncology Laboratory Manager, Haematology Laboratories Gartnavel General Hospital, Glasgow, UK.\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePam McKay\u003c\/b\u003e FRCP FRCPath Consultant Haematologist, Haematology Laboratories and West of Scotland Cancer Centre Gartnavel General Hospital, Glasgow, UK.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eBob Jackson\u003c\/b\u003e MB MRCPI FRCPath Haematopathology Laboratories, Southern General Hospital, Glasgow, UK.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eBarbara J. Bain\u003c\/b\u003e MB BS, FRACP, FRCPath, Professor of Diagnostic Haematology, St Mary’s Hospital Campus of Imperial College Faculty of Medicine, London and Honorary Consultant Haematologist, St Mary’s Hospital, London, UK.\u003c\/p\u003e \u003cp\u003eThe analysis of blood, bone marrow and tissue fluid specimens requires a multi-faceted approach with the integration of scientific data from a number of disciplines. No single discipline can operate in isolation or errors will occur. Flow cytometry is in a privileged position in that it can provide rapid analysis of specimens and it is often the first definitive investigation to produce results and help formulate a working diagnosis.\u003cbr\u003e\u003cbr\u003eThis companion text to \u003ci\u003ePractical Flow Cytometry in Haematology Diagnosis \u003c\/i\u003econtains 100 worked examples drawn from real clinical cases presenting to the authors’ institution. Cases are illustrated with peripheral blood and bone marrow cytology, tissue pathology and cytogenetic and molecular data, which are integrated to generate, where appropriate, a diagnosis based on the \u003ci\u003eWHO Classification of Tumours of Haematopoietic and Lymphoid Tissues\u003c\/i\u003e. The spectrum of clinical cases includes adult and paediatric patients, and both neoplastic and reactive disorders. The cases appear in no particular order to challenge the reader to make their own diagnosis.\u003cbr\u003e\u003cbr\u003eThe reader will review May−Grünwald−Giemsa (MGG)-stained films of peripheral blood and bone marrow aspirates presented alongside flow cytometric data and haematoxylin and eosin (H\u0026amp;E)-stained bone marrow and other tissue biopsy sections. Immunohistochemistry is used to further clarify the tissue lineage and cell differentiation. Cytogenetic studies using metaphase preparations are used to identify translocations and chromosome gains and losses whilst interphase fluorescence \u003ci\u003ein situ\u003c\/i\u003e hybridisation (FISH) studies and polymerase chain reaction (PCR) are used to identify gene fusions, gene rearrangements and deletions. Each case concludes with a discussion of the features that are important to making a diagnosis. The cases are also listed according to disease classification in the appendix so that the text can also be used as a reference.\u003cbr\u003e\u003cbr\u003e\u003ci\u003ePractical Flow Cytometry in Haematology: 100 Worked Examples:\u003cbr\u003e\u003cbr\u003e- \u003c\/i\u003eProvides a practical, example-based resource for flow cytometry \u003cbr\u003e- Demonstrates how flow cytometry results should be interpreted and applied to optimize patient care\u003cbr\u003e- Includes both malignant and benign conditions\u003cbr\u003e- Can be used in conjunction with \u003ci\u003ePractical Flow Cytometry in Haematology Diagnosis\u003c\/i\u003e, by the same author team (ISBN 9780470671207)\u003cbr\u003e\u003cbr\u003e\u003ci\u003ePractical Flow Cytometry in Haematology: 100 Worked Examples\u003c\/i\u003e is ideal for practicing haematologists and histopathologists with an interest in haematopathology, but particularly directed at trainee haematologists and scientists preparing for FRCPath and related examinations.\u003c\/p\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47989831237861,"sku":"NP9781118747032","price":155.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781118747032.jpg?v=1761785608","url":"https:\/\/k12savings.com\/products\/practical-flow-cytometry-in-haematology-isbn-9781118747032","provider":"K12savings","version":"1.0","type":"link"}