{"product_id":"plasmid-biopharmaceuticals-isbn-9780470232927","title":"Plasmid Biopharmaceuticals","description":"The book addresses the basics, applications, and manufacturing of plasmid biopharmaceuticals. The survey of the most relevant characteristics of plasmids provides the basics for designing plasmid products (applications) and processes (manufacturing). Key features that the authors include in the book are: i) consistency and clear line of direction, ii) an extensive use of cross-referencing between the individual chapters, iii) a rational integration of chapters, iv) appellative figures, tables and schemes, and v) an updated, but selected choice of references, with a focus on key papers.  Preface.  \u003cp\u003eAcknowledgment.\u003c\/p\u003e \u003cp\u003eAbbreviations.\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I Basics.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Historical Perspective.\u003c\/p\u003e \u003cp\u003e2 Gene Transfer with Plasmid Biopharmaceuticals.\u003c\/p\u003e \u003cp\u003e3 Product and Process Development.\u003c\/p\u003e \u003cp\u003e4 Structure.\u003c\/p\u003e \u003cp\u003e5 Analytical Characterization.\u003c\/p\u003e \u003cp\u003e6 Delivery.\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart II Applications.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7 Ethical and Safety Issues.\u003c\/p\u003e \u003cp\u003e8 Human and Veterinary Markets.\u003c\/p\u003e \u003cp\u003e9 Human Case Studies: Pandemic Infl uenza and Critical Limb Ischemia.\u003c\/p\u003e \u003cp\u003e10 Veterinary Case Studies: West Nile, Infectious Hematopoietic Necrosis, and Melanoma.\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart III Manufacturing.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11 Good Manufacturing Practice and Validation.\u003c\/p\u003e \u003cp\u003e12 Product Specifi cations and Quality Control.\u003c\/p\u003e \u003cp\u003e13 Cell Culture.\u003c\/p\u003e \u003cp\u003e14 An Overview of Downstream Processing.\u003c\/p\u003e \u003cp\u003e15 Primary Isolation.\u003c\/p\u003e \u003cp\u003e16 Intermediate Recovery.\u003c\/p\u003e \u003cp\u003e17 Final Purifi cation.\u003c\/p\u003e \u003cp\u003e18 Process Synthesis.\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart IV Concluding Remarks and Outlook.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e19 Concluding Remarks and Outlook.\u003c\/p\u003e \u003cp\u003eIndex.\u003c\/p\u003e  \"While very technical and written for practitioners in the field, the writing is direct, and extensive references and a detailed list of abbreviations is included.\" (Book News, 1 October 2011)  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003eDuarte Miguel F. Prazeres, PhD, DSc, is Associate Professor at the Instituto Superior Técnico (IST) and Senior Researcher at the Instituto de Biotecnologia e Bioengenharia, both within the Universidade Técnica de Lisboa. Dr. Prazeres has published 140 peer-reviewed articles and fifteen book chapters on such topics as biocatalysis, downstream processing, and nanobiotechnology.\u003c\/p\u003e  \u003cp\u003eGuides you through every step of development and manufacturing\u003c\/p\u003e \u003cp\u003ePlasmid-based gene transfer techniques have the potential to provide society with a broad new range of therapeutic and prophylactic medicinal agents. Addressing the challenges faced by today's scientists and engineers, this book presents both the fundamentals as well as the latest emerging research in order to explain the characteristics of plasmid DNA and support the development and manufacture of new plasmid biopharmaceuticals.\u003c\/p\u003e \u003cp\u003ePlasmid Biopharmaceuticals is logically organized into three major sections: Basics, Applications, and Manufacturing. Readers will find detailed discussions and reviews of all the key scientific, engineering, and technological breakthroughs and challenges. Moreover, the author delves into key issues in regulation, ethics, markets, and innovation. The final chapter examines how plasmid biopharmaceutical research has evolved and is expected to evolve in the future.\u003c\/p\u003e \u003cp\u003eSeveral features help readers fully grasp new concepts and put them into practice:\u003c\/p\u003e \u003cul\u003e \u003cli\u003e \u003cp\u003eCase studies guide readers through the development of approved products as well as examine products that are still in development stages\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eExtensive cross-referencing among the chapters helps create a complete picture of the development and manufacturing process\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eFigures and diagrams enable readers to better visualize key concepts and procedures\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eTables offer at-a-glance summaries of important information\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eReferences guide readers to landmark papers published in the field\u003c\/p\u003e \u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003ePlasmid Biopharmaceuticals is written for all researchers involved in the development and manufacture of plasmid biopharmaceuticals. Its extensive coverage of fundamentals makes it ideal for novices, whereas its coverage of the latest breakthroughs and challenges makes it equally appropriate for experienced researchers.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989799583973,"sku":"NP9780470232927","price":191.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470232927.jpg?v=1761785514","url":"https:\/\/k12savings.com\/products\/plasmid-biopharmaceuticals-isbn-9780470232927","provider":"K12savings","version":"1.0","type":"link"}