{"product_id":"pathology-of-genetically-engineered-and-other-mutant-mice-isbn-9781119624578","title":"Pathology of Genetically Engineered and Other Mutant Mice","description":"\u003cp\u003e\u003cb\u003eAn updated and comprehensive reference to pathology in every organ system in genetically modified mice\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eThe newly revised and thoroughly updated Second Edition of \u003ci\u003ePathology of Genetically Engineered and Other Mutant Mice\u003c\/i\u003e delivers a comprehensive resource for pathologists and biomedical scientists tasked with identifying and understanding pathologic changes in genetically modified mice. The book is organized by body system, includes descriptions and explanations of a wide range of findings, as well as hundreds of color photographs illustrating both common and rare lesions that may be found in genetically engineered and wild type mice. \u003c\/p\u003e\u003cp\u003eThe book is written by experienced veterinary and medical pathologists working in veterinary medical colleges, medical colleges, and research institutes. Covering the latest discoveries in mouse pathology resulting from advancements in biotechnology research over the last 30 years, this singular and accessible resource is a must-read for veterinary and medical pathologists and researchers working with genetically engineered and other mice. \u003c\/p\u003e\u003cp\u003eReaders will also benefit from: \u003c\/p\u003e\u003cul\u003e \u003cli\u003eA thorough introduction to mouse pathology and mouse genetic nomenclature, as well as databases useful for analysis of mutant mice\u003c\/li\u003e \u003cli\u003eAn exploration of concepts related to validating animal models, including the Cinderella Effect\u003c\/li\u003e \u003cli\u003ePractical discussions of basic necropsy methods and grading lesions for computational analyses\u003c\/li\u003e \u003cli\u003eConcise diagnostic approaches to the respiratory tract, the oral cavity and GI tract, the cardiovascular system, the liver and pancreas, the skeletal system, and other tissues\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eAs a one-stop and up to date reference on mouse pathology,\u003ci\u003e Pathology of Genetically Engineered and Other Mutant Mice\u003c\/i\u003e is an essential book for veterinary and medical pathologists, as well as for scientists, researchers, and toxicologists whose work brings them into contact with genetically modified mice. \u003c\/p\u003e\u003cp\u003eList of Contributors vii\u003c\/p\u003e \u003cp\u003ePreface and Acknowledgments x\u003c\/p\u003e \u003cp\u003e1 Introduction to Mouse Pathology 1\u003ci\u003e\u003cbr\u003e Jerrold M. Ward, Peter Vogel, and John P. Sundberg\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 The Mouse Online: Open Mouse Biology and Pathology Data Resources for Biomedical Research 6\u003cbr\u003e \u003ci\u003eDale A. Begley, Paul N. Schofield, and John P. Sundberg\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Mouse Genetic Nomenclature: The Underpinning of Mouse Genetics 22\u003ci\u003e\u003cbr\u003e John P. Sundberg, Dale A. Begley, Melissa L. Berry, Michelle N. Perry, David Shaw, and Paul N. Schofield\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Discovering and Validating Mouse Models of Human Diseases: The Cinderella Effect 39\u003ci\u003e\u003cbr\u003e John P. Sundberg, Jerrold M. Ward, Peter Vogel, and Paul N. Schofield\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Embryos, Placentas, and Neonates 48\u003ci\u003e\u003cbr\u003e Brad Bolon and Jerrold M. Ward\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Ciliopathies 72\u003ci\u003e\u003cbr\u003e Peter Vogel and Laura J. Janke\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Hematopoietic and Lymphoid Tissues 82\u003ci\u003e\u003cbr\u003e Harm HogenEsch and John P. Sundberg\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Mouse Hematolymphoid Neoplasms 97\u003ci\u003e\u003cbr\u003e Jerold E. Rehg\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Immunodeficient and Humanized Mice 132\u003ci\u003e\u003cbr\u003e Sara F. Santagostino, Sébastien Monette, Alessandra Piersigilli, Virginia L. Godfrey, and Harm HogenEsch\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Skin, Hair, and Nails 159\u003ci\u003e\u003cbr\u003e John P. Sundberg, Lloyd E. King, Jr, and Raoul V. Kuiper\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Mammary Gland 213\u003ci\u003e\u003cbr\u003e Alexander D. Borowsky and Robert D. Cardiff\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 The Respiratory Tract 237\u003ci\u003e\u003cbr\u003e Jerrold M. Ward and John P. Sundberg\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 The Gastrointestinal Tract 259\u003ci\u003e\u003cbr\u003e Jerrold M. Ward, Piper M. Treuting, and M. Kay Washington\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 Cardiovascular System 284\u003ci\u003e\u003cbr\u003e Kathleen L. Gabrielson, Akash Behera, Polina Sysa-Shah, Tyler J. Creamer, and Timothy K. Cooper\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Liver and Pancreas 307\u003ci\u003e\u003cbr\u003e Maria L.Z. Dagli, Lucas M. Chaible, and Katja Steiger\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16 Neuromuscular System 336\u003ci\u003e\u003cbr\u003e Peter Vogel, Laura J. Janke, and Heather W. Sheppard\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17 Endocrine System 355\u003ci\u003e\u003cbr\u003e Krista M. D. La Perle\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18 Kidney and Urinary Bladder 378\u003ci\u003e\u003cbr\u003e Jeffrey B. Kopp, Avi Z. Rosenberg, Cory F. Brayton, Jeffrey I. Everitt, and Jerrold M. Ward\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e19 Female Reproductive System 403\u003ci\u003e\u003cbr\u003e Darlene Dixon and Alexander Yu. Nikitin (In Memory of Dr. Joel Mahler)\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e20 Male Reproductive System 431\u003ci\u003e\u003cbr\u003e Sue E. Knoblaugh, Hibret A. Adissu, Colin McKerlie, and Robert D. Cardiff\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e21 Nervous System 462\u003ci\u003e\u003cbr\u003e Jessica M. Snyder, Katherine N. Gibson-Corley, and Enrico Radaelli\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e22 Eye and Ear 493\u003ci\u003e\u003cbr\u003e Heather W. Sheppard, Laura J. Janke, Jerold E. Rehg, and Peter Vogel\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e23 Bones and Teeth 520\u003ci\u003e\u003cbr\u003e Peter Vogel, John P. Sundberg, and Cheryl Ackert-Bicknell\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 541\u003c\/p\u003e \u003cp\u003e\u003cb\u003eThe editors\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eJohn P. Sundberg\u003c\/b\u003e, DVM, PhD, DACVP, is Professor at The Jackson Laboratory in Bar Harbor, Maine, USA and an Adjunct Professor in the Department of Dermatology, Vanderbilt University Medical Center in Nashville, TN, USA.\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePeter Vogel\u003c\/b\u003e, DVM, PhD, DACVP, is Director of the Veterinary Pathology Core Laboratory at St. Jude Children's Research Hospital in Memphis, Tennessee, USA.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eJerrold M. Ward\u003c\/b\u003e, DVM, PhD, DACVP, FIATP,is an Adjunct Faculty member at The Jackson Laboratory, Bar Harbor, Maine, USA and Adjunct Professor in the Department of Biomedical Sciences at Cornell University College of Veterinary Medicine in Ithaca, New York, USA.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eAn updated and comprehensive reference to pathology in every organ system in genetically modified mice\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eThe newly revised and thoroughly updated Second Edition of \u003ci\u003ePathology of Genetically Engineered and Other Mutant Mice\u003c\/i\u003e delivers a comprehensive resource for pathologists and biomedical scientists tasked with identifying and understanding pathologic changes in genetically modified mice. The book is organized by body system, and includes descriptions and explanations of a wide range of findings, as well as hundreds of color photographs illustrating both common and rare lesions that may be found in genetically engineered and wild type mice. \u003c\/p\u003e\u003cp\u003eThe book is written by experienced veterinary and medical pathologists working in veterinary medical colleges, medical colleges, and research institutes. Covering the latest discoveries in mouse pathology resulting from advancements in biotechnology research over the last 30 years, this singular and accessible resource is a must-read for veterinary and medical pathologists and researchers working with genetically engineered and other mice. \u003c\/p\u003e\u003cp\u003eReaders will also benefit from: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eA thorough introduction to mouse pathology and mouse genetic nomenclature, as well as databases useful for analysis of mutant mice\u003c\/li\u003e \u003cli\u003eAn exploration of concepts related to validating animal models, including the Cinderella Effect\u003c\/li\u003e \u003cli\u003ePractical discussions of basic necropsy methods and grading lesions for computational analyses\u003c\/li\u003e \u003cli\u003eConcise diagnostic approaches to the respiratory tract, the oral cavity and GI tract, the cardiovascular system, the liver and pancreas, the skeletal system, and other tissuesl\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003eAs a one-stop and up to date reference on mouse pathology, \u003ci\u003ePathology of Genetically Engineered and Other Mutant Mice\u003c\/i\u003e is an essential book for veterinary and medical pathologists, as well as for scientists, researchers, and toxicologists whose work brings them into contact with genetically modified mice.\u003c\/p\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47989754265829,"sku":"NP9781119624578","price":242.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781119624578.jpg?v=1761785362","url":"https:\/\/k12savings.com\/products\/pathology-of-genetically-engineered-and-other-mutant-mice-isbn-9781119624578","provider":"K12savings","version":"1.0","type":"link"}