{"product_id":"oxidative-stress-and-cardiac-failure-isbn-9780879937096","title":"Oxidative Stress and Cardiac Failure","description":"Far from being a direct complication of primary damage to heart muscle, it is now recognised that the pathogenesis of heart failure may rely on a combination of neurohormonal, cellular and molecular factors. An overwhelming number of systems appear to be activated in heart failure and contribute in some way towards structural remodelling. \u003cp\u003eComprising a comprehensive evaluation of the experimental and clinical data relating oxidative stress and heart failure, this text proposes that oxidative stress may be the common pathway for muscle dysfunction, cellular growth and remodelling, and mytocyte death. Acknowledged experts in the field here present a persuasive argument for raising the profile of oxidative stress as an important, perhaps critical contributor to the adverse consequences of heart failure. This volume should serve as a rich source of supportive data for clinicians and investigators interested in the pathophysiology and treatment of heart failure, and as a platform on which to base further research.\u003c\/p\u003e  Foreword: \u003ci\u003eJay N. Cohn\u003c\/i\u003e . \u003cp\u003eIntroduction: \u003ci\u003eMarrick L. Kukin.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eContributors.\u003c\/p\u003e \u003cp\u003eAbbreviations Used in This Book.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eI. Current Concepts in Heart Failure.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1. Natural History of Heart Failure.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eW.H. Wilson Tang and Gary S. Francis.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2. Pathophysiology of Chronic Heart Failure.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eTatiana Tsvetkova and Michael R. Bristow\u003c\/i\u003e.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eII. Pathophysiology, Clinical, and Laboratory Evidence of Oxidative Stress in Heart Failure.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3. Chemistry of Free Radicals in Biological Systems.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eJay L. Zweier and Frederick A. Villamena\u003c\/i\u003e.\u003c\/p\u003e \u003cp\u003e4. Evidence of Oxidative Stress in Heart Failure.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eKenneth Y.K. Wong, Allan D. Struthers, and Jill J.F. Belch\u003c\/i\u003e.\u003c\/p\u003e \u003cp\u003e5. Animal Models: Apoptosis and Oxidative Stress.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eHani N. Sabbah and Elaine J. Tanhehco\u003c\/i\u003e.\u003c\/p\u003e \u003cp\u003e6. Oxygen Free Radicals, Iron, and Cytokines in Heart Failure: From Bench to Bedside.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eMona Shawky, Neelam Khaper, and Peter Liu.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7. Adrenergic and Mechanical Regulation of Oxidative Stress in the Myocardium.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eDeborah A. Siwik, David R. Pimentel, Lei Xiao, Krisha Singh, Douglas B. Sawyer, and Wilson S. Colucci.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eIII. Therapeutic Pathways and Modulation of Oxidative Stress.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8. Beta-Blockers and Oxidative Stress.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eMarrick L. Kukin.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9. Angiotensin-Converting Enzyme Inhibitors and Oxidative Stress.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eBalkrishna Singh and William T. Abraham.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10. Angiotensin II Receptor Blockers and Oxidative Stress.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eColin Berry and John McMurray\u003c\/i\u003e.\u003c\/p\u003e \u003cp\u003e11. Microvasculature and Oxidative Stress, With Special Emphasis on the Acute Coronary Syndromes.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eMardi Gomberg-Maitland and Valentin Fuster.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12. The Role of Reactive Oxygen Species in the Pathogenesis of Endothelial Dysfunction in Patients with Chronic Heart Failure.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eHaoyi Zheng, Henry Krum, and Stuart D. Katz.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13. Antioxidant Vitamins and Apoptosis.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eFuzhong Qin and Chang-seng Liang\u003c\/i\u003e.\u003c\/p\u003e \u003cp\u003eIndex\u003c\/p\u003e \u003ci\u003e\"The authors, experts in the field, describe the methods and results of their studies conducted in their own laboratory. Nevertheless, the authors manage to keep the text focused and quite comprehensible for the general clinician...\u003c\/i\u003e \u003cp\u003e\u003ci\u003e\"This book provides a comprehensive overview of the heart failure syndrome and the evidence of the role of oxidative stress in its development...\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003e\"This book can be useful for clinicians to further their understanding of the pathogenesis of heart failure and how the different therapeutic pathways may improve mortality and morbidity. Furthermore, for those who are currently pursuing research in this field, the book serves as an excellent reference guide in addition to being a source of ideas and encouragement.\"\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eJose C Mendez, MD (Loyola University Stritch School of Medicine)\u003cbr\u003e Doody's Review Service\u003cbr\u003e\u003cbr\u003e\u003c\/b\u003e\"This book provides a comprehensive overview of the heart failure syndrome and the evidence of the role of oxidative stress in its development. The tables and illustrations in the book help to deepen the understanding of the text.  This book can be useful for clinicians to further their understanding of the pathogenesis of heart failure and how the different therapeutic pathways may improve mortality and morbidity. Furthermore, for those who are currently pursuing research in this field, the book serves as an excellent reference guide in addition to being a source of ideas and encouragement.\" (Jose C Mendez, MD, @Doody's Review Service)\u003c\/p\u003e  \u003cp\u003e\u003cstrong\u003eMarrick Kukin\u003c\/strong\u003e is the editor of \u003cem\u003eOxidative Stress and Cardiac Failure\u003c\/em\u003e, published by Wiley. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eValentin Fuster\u003c\/strong\u003e is the editor of \u003cem\u003eOxidative Stress and Cardiac Failure\u003c\/em\u003e, published by Wiley.   Far from being a direct complication of primary damage to heart muscle, it is now recognised that the pathogenesis of heart failure may rely on a combination of neurohormonal, cellular and molecular factors. An overwhelming number of systems appear to be activated in heart failure and contribute in some way towards structural remodelling. \u003c\/p\u003e\u003cp\u003eComprising a comprehensive evaluation of the experimental and clinical data relating oxidative stress and heart failure, this text proposes that oxidative stress may be the common pathway for muscle dysfunction, cellular growth and remodelling, and mytocyte death. Acknowledged experts in the field here present a persuasive argument for raising the profile of oxidative stress as an important, perhaps critical contributor to the adverse consequences of heart failure. This volume should serve as a rich source of supportive data for clinicians and investigators interested in the pathophysiology and treatment of heart failure, and as a platform on which to base further research.\u003c\/p\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47989745254629,"sku":"NP9780879937096","price":166.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780879937096.jpg?v=1761785325","url":"https:\/\/k12savings.com\/products\/oxidative-stress-and-cardiac-failure-isbn-9780879937096","provider":"K12savings","version":"1.0","type":"link"}