{"product_id":"organic-synthesis-isbn-9780471929635","title":"Organic Synthesis","description":"\u003cp\u003e\u003ci\u003eOrganic Synthesis: Strategy and Control\u003c\/i\u003e is a sequel to Stuart Warren's bestseller \u003ci\u003eOrganic Synthesis: The Disconnection Approach\u003c\/i\u003e. The 'Disconnection' book concentrated on the planning behind the synthesis of compounds.\u003c\/p\u003e \u003cp\u003eThe two themes of this new book are \u003ci\u003estrategy\u003c\/i\u003e and \u003ci\u003econtrol:\u003c\/i\u003e solving problems either by finding an alternative strategy or by controlling any established strategy to make it work.\u003c\/p\u003e \u003cp\u003eThe book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry and functional group strategy. Interpenetrating this structure, the 36 chapters start with classic methods and progress to modern methods and modern strategic considerations. Heterocyclic chemistry is treated throughout the book with full mechanistic explanations as part of organic chemistry rather than a separate mystery.\u003c\/p\u003e \u003cul\u003e \u003cli\u003eA comprehensive, practical account of the key concepts involved in synthesising compounds.\u003c\/li\u003e \u003cli\u003eTakes a mechanistic approach, which explains reactions and gives guidelines on how reactions might behave in different situations.\u003c\/li\u003e \u003cli\u003eFocuses on reactions that really work rather than those with limited application.\u003c\/li\u003e \u003cli\u003eExtensive, up-to-date references in each chapter.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eStudents and professional chemists familiar with \u003ci\u003eOrganic Synthesis: The Disconnection Approach\u003c\/i\u003e will enjoy the leap into a book designed for chemists at the coalface of organic synthesis.\u003c\/p\u003e A: Introduction: Selectivity.\u003cbr\u003e \u003cbr\u003e 1. Planning Organic Syntheses: Tactics, Strategy, and Control.\u003cbr\u003e \u003cbr\u003e 2. Chemoselectivity.\u003cbr\u003e \u003cbr\u003e 3. Regioselectivity: Controlled Aldol Reactions.\u003cbr\u003e \u003cbr\u003e 4. Stereoselectivity: Stereoselective Aldol Reactions.\u003cbr\u003e \u003cbr\u003e 5. Alternative Strategies for Enone Synthesis.\u003cbr\u003e \u003cbr\u003e 6. Choosing a Strategy : The Synthesis of cyclopentenones.\u003cbr\u003e \u003cbr\u003e B: Making Carbon-Carbon Bonds.\u003cbr\u003e \u003cbr\u003e 7. The Ortho Strategy for Aromatic Compounds.\u003cbr\u003e \u003cbr\u003e 8. ´-Complexes of Metals.\u003cbr\u003e \u003cbr\u003e 9. Controlling the Michael Reaction.\u003cbr\u003e \u003cbr\u003e 10. Specific Enol Equivalents.\u003cbr\u003e \u003cbr\u003e 11. Extended Enolates.\u003cbr\u003e \u003cbr\u003e 12. Allyl Anions.\u003cbr\u003e \u003cbr\u003e 13. Homoenolates.\u003cbr\u003e \u003cbr\u003e 14. Acyl Anion Equivalents.\u003cbr\u003e \u003cbr\u003e C: Carbon-Carbon Double Bonds.\u003cbr\u003e \u003cbr\u003e 15. Synthesis of Double Bonds of Defined Stereochemistry.\u003cbr\u003e \u003cbr\u003e 16. Stereo-Controlled Vinyl Anion Equivalents.\u003cbr\u003e \u003cbr\u003e 17. Electrophilic Attack on Alkenes.\u003cbr\u003e \u003cbr\u003e 18. Vinyl Cations: Palladium-Catalysed C-C Coupling.\u003cbr\u003e \u003cbr\u003e 19. Allyl Alcohols: Allyl Cation Equivalents (and More).\u003cbr\u003e \u003cbr\u003e D: Stereochemistry.\u003cbr\u003e \u003cbr\u003e 20. Control of Stereochemistry -- Introduction.\u003cbr\u003e \u003cbr\u003e 21 Controlling Relative Stereochemistry.\u003cbr\u003e \u003cbr\u003e 22. Resolution.\u003cbr\u003e \u003cbr\u003e 23. The Chiral Pool.\u003cbr\u003e \u003cbr\u003e 24. Asymmetric Induction I: Reagent-Based Strategy.\u003cbr\u003e \u003cbr\u003e 25. Asymmetric Induction II: Asymmetric Catalysis: Formation of C-O and C-N Bonds.\u003cbr\u003e \u003cbr\u003e 26. Asymmetric Induction III: Asymmetric Catalysis: Formation of C-H and C-C Bonds.\u003cbr\u003e \u003cbr\u003e 27. Asymmetric Induction IV: Substrate-Based Strategy.\u003cbr\u003e \u003cbr\u003e 28. Kinetic Resolution.\u003cbr\u003e \u003cbr\u003e 29. Enzymes: Biological Methods in Asymmetric Synthesis.\u003cbr\u003e \u003cbr\u003e 30. New Chiral Centres from Old.\u003cbr\u003e \u003cbr\u003e 31. Strategy of Asymmetric Synthesis.\u003cbr\u003e \u003cbr\u003e E: Functional Group Strategy.\u003cbr\u003e \u003cbr\u003e 32. Functionalisation of Pyridine.\u003cbr\u003e \u003cbr\u003e 33. Oxidation of Aromatic Compounds, Enols and Enolates.\u003cbr\u003e \u003cbr\u003e 34. Functionality and Pericyclic Reactions: Nitrogen Heterocycles by Cycloadditions and Sigmatropic Rearrangements.\u003cbr\u003e \u003cbr\u003e 35. Synthesis and Chemistry of Azoles and other Heterocycles with Two or more Heteroatoms.\u003cbr\u003e \u003cbr\u003e 36. Tandem Organic Reactions.\u003cbr\u003e \u003cbr\u003e General References.\u003cbr\u003e \u003cbr\u003e Index. This is a book which will change the way you think about making molecules. (Chemistry World, July 2008)\u003cbr\u003e \u003cbr\u003e The authors can be commended on producing a really useful and enjoyable new book on Organic Synthesis. (Reviews, June 2008)\u003cbr\u003e \u003cbr\u003e \"The authors have spent approximately ten years putting this excellent book together, and their hard work has paid off.\" (Journal of Chemical Education, May 2008)\u003cbr\u003e \u003cbr\u003e \"Of interest to the experienced practitioner looking to broaden (or reawaken) awareness of the remarkable diversity of available synthetic transformations\"(Journal of Medicinal Chemistry, 2008) \u003cp\u003e\u003cb\u003ePaul Wyatt\u003c\/b\u003e, Senior Lecturer and Director of Undergraduate Studies, School of Chemistry, University of Bristol, UK.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eStuart Warren\u003c\/b\u003e, Reader in Organic Chemistry, Department of Chemistry, University of Cambridge, UK.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eOrganic Synthesis: Strategy and Control\u003c\/i\u003e is a sequel to Stuart Warren's bestseller \u003ci\u003eOrganic Synthesis: The Disconnection Approach\u003c\/i\u003e. The 'Disconnection' book concentrated on the planning behind the synthesis of compounds.\u003c\/p\u003e \u003cp\u003eThe two themes of this new book are \u003ci\u003estrategy\u003c\/i\u003e and \u003ci\u003econtrol:\u003c\/i\u003e solving problems either by finding an alternative strategy or by controlling any established strategy to make it work.\u003c\/p\u003e \u003cp\u003eThe book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry and functional group strategy. Interpenetrating this structure, the 36 chapters start with classic methods and progress to modern methods and modern strategic considerations. Heterocyclic chemistry is treated throughout the book with full mechanistic explanations as part of organic chemistry rather than a separate mystery.\u003c\/p\u003e \u003cul\u003e \u003cli\u003eA comprehensive, practical account of the key concepts involved in synthesising compounds.\u003c\/li\u003e \u003cli\u003eTakes a mechanistic approach, which explains reactions and gives guidelines on how reactions might behave in different situations.\u003c\/li\u003e \u003cli\u003eFocuses on reactions that really work rather than those with limited application.\u003c\/li\u003e \u003cli\u003eExtensive, up-to-date references in each chapter.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eStudents and professional chemists familiar with \u003ci\u003eOrganic Synthesis: The Disconnection Approach\u003c\/i\u003e will enjoy the leap into a book designed for chemists at the coalface of organic synthesis.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989734736101,"sku":"NP9780471929635","price":82.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780471929635.jpg?v=1761785296","url":"https:\/\/k12savings.com\/products\/organic-synthesis-isbn-9780471929635","provider":"K12savings","version":"1.0","type":"link"}