{"product_id":"organic-syntheses-collective-volume-12-isbn-9781118117828","title":"Organic Syntheses, Collective Volume 12","description":"\u003cp\u003eContinuing the tradition of providing significant and interesting procedures, \u003ci\u003eOrganic Syntheses, Collective Volume XII\u003c\/i\u003e is a compilation of revised editions of \u003ci\u003eAnnual Volumes 85 through 89\u003c\/i\u003e. The contents of this volume are organized by primarily by reaction type, with the precise classification made according to the bias of the editor, who attempted to ascertain the primary purpose or utility of the procedure.\u003c\/p\u003e \u003cp\u003ePreparation of (E)-(2-Iodovinyl)Benzene from Benzyl Bromide and Diiodomethane [(E)-β-StyrylIodide] 1\u003c\/p\u003e \u003cp\u003eVinylation with Inexpensive Silicon-Based Reagents: Preparation of 3-Vinylquinoline and 4-Vinylbenzophenone 7\u003c\/p\u003e \u003cp\u003eOrganolithiums and Lithium 2,2,6,6-Tetramethylpiperidide in Reductive Alkylation of Epoxides: Synthesis of (E)-Alkenes [(E)-2-Methyltetradeca-1,3-Diene] 19\u003c\/p\u003e \u003cp\u003e2-MethylenecyclopropanecarboxylicAcidEthylEster 27\u003c\/p\u003e \u003cp\u003e2-(2,2-Dibromoethenyl)-benzenamine 33\u003c\/p\u003e \u003cp\u003eStereoselective Nickel-Catalyzed 1,4-Hydroboration of 1,3-Dienes [(Z)-Dec-2-en-1-ol] 42\u003c\/p\u003e \u003cp\u003eSynthesisofEthyl2-Ethanoyl-2-methyl-3-phenylbut-3-enoate 51\u003c\/p\u003e \u003cp\u003e(±) trans-3,3′ -(1,2-Cyclopropanediyl)bis-2-(E)-Propenoic Acid, Diethyl Ester: Tandem Oxidation Procedure (Top) Using Mno 2 Oxidation-Stabilized Phosphorane Trapping 57\u003c\/p\u003e \u003cp\u003eStereoselective Synthesis of 3-Arylacrylates by Copper-Catalyzed Syn Hydroarylation [(E)-Methyl 3-phenyloct-2-enoate] 67\u003c\/p\u003e \u003cp\u003eTandem Nucleophilic Addition\/Fragmentation of Vinylogous Acyl Triflates:2-Methyl-2-(1-oxo-5-heptynyl)-1,3-dithiane 72\u003c\/p\u003e \u003cp\u003eSynthesis of Ynamides by Copper-Mediated Coupling of 1,1-Dibromo-1-Alkenes with Nitrogen Nucleophiles Preparation of 4-Methyl-N-(2-Phenylethynyl)-N- (Phenylmethyl)Benzenesulfonamide 81\u003c\/p\u003e \u003cp\u003eSynthesis of Polyynes by In Situ Desilylative Bromination and Palladium-Catalyzed Coupling: (7-(Benzyloxy)hepta-1,3,5-triynyl)triisopropylsilane 93\u003c\/p\u003e \u003cp\u003ePreparation of a 1-Alkoxy-1-Alkyne from Reaction of a 2,2,2-Trifluoroethyl Ether with an Alkyllithium Reagent: 1-Benzyloxymethoxy-1-Hexyne 103\u003c\/p\u003e \u003cp\u003eAn Economical Synthesis of 4-Trimethylsilyl-2-butyn-1-ol 110\u003c\/p\u003e \u003cp\u003eSingle-Step Synthesis of Alkynyl Imines from N-Vinyl and N-Aryl Amides. Synthesis of N-[1-Phenyl-3-(Trimethylsilyl)-2-Propynylidene]-Benzenamine 121\u003c\/p\u003e \u003cp\u003eLithiated Primary Alkyl Carbamates for the Homologation of BoronicEsters 127\u003c\/p\u003e \u003cp\u003eSynthesis of (R)-2-Methoxy-N-(1-Phenylethyl)Acetamide via DynamicKineticResolution 138\u003c\/p\u003e \u003cp\u003eSynthesis and Resolution of Racemic trans-2-(N-Benzyl)amino-1-cyclohexanol: Enantiomer Separation by Sequential Use of (R)- and (S)-Mandelic Acid [Cyclohexanol, 2-(N-benzyl)amino, (1S,2S)- and (1R,2R)-] 147\u003c\/p\u003e \u003cp\u003e(S a ,S)-N-[2 ′ -(4-Methylphenylsulfonamido)-1,1á- Binaphthyl-2-yl]pyrrolidine-2-carboxamide: An OrganocatalystfortheDirectAldolReaction 157\u003c\/p\u003e \u003cp\u003eSynthesis of (S)-8a-Methyl-3,4,8,8a-Tetrahydro-1,6-(2H,7H)- Naphthalenedione via N-Tosyl-(S a)-BINAM-L-Prolinamide Organocatalysis 168\u003c\/p\u003e \u003cp\u003e(S)-(–)-2-Allylcyclohexanone (2-Allylcyclohexan-1-one) 177\u003c\/p\u003e \u003cp\u003eSynthesis and Diastereoselective Aldol Reactions of a Thiazolidinethione Chiral Auxiliary 187\u003c\/p\u003e \u003cp\u003eLithium Amides as Homochiral AmmoniaEquivalents for Conjugate Additions to α,β-Unsaturated Esters: Asymmetric Synthesis of (S)-β-Leucine 198\u003c\/p\u003e \u003cp\u003eFluoride Ring-Opening Kinetic Resolution of Terminal Epoxides: Preparation of (S)-2-Fluoro-1-Phenylethanol 214\u003c\/p\u003e \u003cp\u003e(R)-3,3′ -Bis(9-Phenanthryl)-1,1 ′ -Binaphthalene-2,2 ′ -Diyl Hydrogen Phosphate 222\u003c\/p\u003e \u003cp\u003eEnantioselective Three-Component Reaction for the Preparation of β-Amino-α-HydroxyEsters 232\u003c\/p\u003e \u003cp\u003ePreparation of H, 4 PyrrolidineQuin-BAM(PBAM) 241\u003c\/p\u003e \u003cp\u003eSynthesis of tert-Butyl (1S,2S)-2-Methyl-3-Oxo-1-Phenyl ropylcarbamatebyAsymmetricMannichReaction 253\u003c\/p\u003e \u003cp\u003ePreparation of (R a)-Methyl 3-(Dimethyl(phenyl)silyl)hexa-3,4- dienoate 258\u003c\/p\u003e \u003cp\u003ePreparation of (S)-3,3 ′ -Bis-Morpholinomethyl-5,5′ ,6,6′ ,7,7′ ,8,8′ - Octahydro-1,1′ -Bi-2-Naphthol 268\u003c\/p\u003e \u003cp\u003eCatalytic Asymmetric Addition of an In-Situ Prepared Arylzinc to Cyclohexanecarboxaldehyde: (R)-(+)-α-Cyclohexyl-3- Methoxy-Benzenemethanol 276\u003c\/p\u003e \u003cp\u003ePreparation of (S)-4-Isopropyl-N-Propanoyl-1,3-Thiazolidine-2- Thione 283\u003c\/p\u003e \u003cp\u003eStereoselective Synthesis of Anti α-Methyl-β-Methoxy Carboxylic Compounds 292\u003c\/p\u003e \u003cp\u003eOrganocatalytic Enantioselective Synthesis of Bicyclic β-Lactones from Aldehyde Acids via Nucleophile-Catalyzed Aldol-Lactonization(NCAL) 301\u003c\/p\u003e \u003cp\u003eSynthesis of (+)-B-Allyldiisopinocampheylborane and Its Reaction withAldehydes 316\u003c\/p\u003e \u003cp\u003eSynthesis of (S,S)-Diisopropyl Tartrate (E)-Crotylboronate and Its Reaction with Aldehydes: (2R,3R,4R)-1,2-Dideoxy-2- Ethenyl-4,5-O-(1-Methylethylidene)-Xylitol 330\u003c\/p\u003e \u003cp\u003eBenzyl Isopropoxymethyl Carbamate – An Aminomethylating Reagent for Mannich Reactions of Titanium Enolates 344\u003c\/p\u003e \u003cp\u003e(R)-2-(Benzyloxycarbonylamino-Methyl)-3-Phenylpropanoic Acid (Z-β 2 hPhe-OH): Preparation of a β 2 -Amino Acid with the Auxiliary Dioz 350\u003c\/p\u003e \u003cp\u003eCatalytic Enantioselective Addition of Terminal Alkynes to Aldehydes: Preparation of (S)-(-)-1,3-Diphenyl-2-propyn-1-ol and (S)-(-)-4-Methyl-1-phenyl-2-pentyn-1,4-diol 358\u003c\/p\u003e \u003cp\u003ePreparation of (S)-tert-ButylPHOX (Oxazole, 4-(1,1-dimethylethyl) -2-[2-(diphenylphosphino)phenyl]-4,5-dihydro- (4S)-) 368\u003c\/p\u003e \u003cp\u003ePreparation of (S)-2-Allyl-2-Methylcyclohexanone (Cyclohexanone, 2-methyl-2-(2-propen-1-yl)-, (2S)-) 379\u003c\/p\u003e \u003cp\u003eHigh-Yielding, Large-Scale Synthesis of N-Protected-β- Aminonitriles: tert-Butyl (1R)-2-Cyano-1- Phenylethylcarbamate 395\u003c\/p\u003e \u003cp\u003e(3R,7aS)-3-(Trichloromethyl)Tetrahydropyrrolo[1,2-C]Oxazol-1(3H)-one: An Air and Moisture Stable Reagent for the Synthesis of Optically Active α-BranchedProlines 405\u003c\/p\u003e \u003cp\u003ePreparation of Enantioenriched Homoallylic Primary Amines 415\u003c\/p\u003e \u003cp\u003eSynthesis of (2R,3R)-2,3-Dimethyl-1,4-Butanediol by Oxidative Homocoupling of (4S)-Isopropyl-3-Propionyl-2-Oxazolidinone[2,3-Dimethylbutane-1,4-diol, (2R, 3R)-] 423\u003c\/p\u003e \u003cp\u003eOxone R -Mediated Synthesis of Benzimidazoles from 1,2-Phenylenediamines and Aldehydes: Preparation of 2-(4-Cyano-Phenyl)-1-[2-(3,4-Dimethoxyphenyl)-Ethyl]- 1H-Benzimidazole-5-CarboxylicAcidEthylEster 435\u003c\/p\u003e \u003cp\u003eSynthesis of a N-Mesityl-Substituted Aminoindanol-Derived Triazolium Salt [(5aS,10bR)-5a,10b-Dihydro-2-\u003c\/p\u003e \u003cp\u003e(2,4,6-trimethylphenyl)-4H,6H-indeno[2,1-b]-1,2, 4-triazolo[4,3-d]-1,4-oxaziniumchloride] 446\u003c\/p\u003e \u003cp\u003e\u003ci\u003et-Butyl as a Pyrazole Protecting Group: Preparation and Use of \u003c\/i\u003e1-tert-Butyl-3-Methyl-1H-Pyrazole-5-Amine 459\u003c\/p\u003e \u003cp\u003eMicrowave-Assisted Synthesis of 1,3-Dimesitylimidazolinium Chloride 470\u003c\/p\u003e \u003cp\u003eRegioselective Synthesis of 1,3,5-Trisubstituted Pyrazoles by the Reaction of N-Monosubstituted HydrazoneswithNitroolefins 479\u003c\/p\u003e \u003cp\u003eSynthesisof4,5-Dimethyl-1,3-dithiol-2-one 487\u003c\/p\u003e \u003cp\u003eCu-Catalyzed Azide-Alkyne Cycloaddition: Preparation of Tris((1-Benzyl-1H-1,2,3-Triazolyl)Methyl)Amine 497\u003c\/p\u003e \u003cp\u003eAn Intramolecular Amination of Aryl Halides with a Combination of Copper (I) Iodide and Cesium Acetate: Preparation of 5,6-Dimethoxyindole-1,2-Dicarboxylic Acid 1-Benzyl Ester 2-MethylEster 504\u003c\/p\u003e \u003cp\u003ePreparation of a Non-Symmetrical Imidazolium Salt: 1-Adamantyl-3-Mesityl-4,5-Dimethylimidazolium Tetrafluoroborate 512\u003c\/p\u003e \u003cp\u003eEfficient Oxidative Synthesis of (-)-2-tert-Butyl-(4S)-Benzyl-(1,3)-Oxazoline 520\u003c\/p\u003e \u003cp\u003eSynthesis of Enantiopure Di(tert-Butyl) (2S,4S)-4-Hydroxy-6-Oxo-1,2-Piperidinedicarboxylate.\u003c\/p\u003e \u003cp\u003eA Useful Building Block for the Preparation of 4-HydroxypipecolateDerivatives 529\u003c\/p\u003e \u003cp\u003eConvenient Preparation of 3-Ethoxycarbonyl Benzofurans from SalicylaldehydesandEthylDiazoacetate 537\u003c\/p\u003e \u003cp\u003eOne-Pot Multicomponent Preparation of Tetrahydropyrazoloquinolinones and Tetrahydropyrazoloquinazolinones 545\u003c\/p\u003e \u003cp\u003eSynthesis of 2-Arylindole-4-Carboxylic Amides: [2-(4- Fluorophenyl)-1H-Indol-4-yl]-1- Pyrrolidinylmethanone 554\u003c\/p\u003e \u003cp\u003eOne-Pot Synthesis of 5H-Indazolo-[3,2-b]Benzo[d]-1,3-Oxazine: Two Efficient Preparative Methods 566\u003c\/p\u003e \u003cp\u003ePhosphine-Catalyzed [4+2] Annulation: Synthesis of Ethyl 6-Phenyl-1-Tosyl-1,2,5,6-Tetrahydropyridine-3-Carboxylate 575\u003c\/p\u003e \u003cp\u003ePhosphine-Catalyzed [3 + 2] Annulation: Synthesis of Ethyl 5-(tert-Butyl)-2-Phenyl-1-Tosyl-3-Pyrroline-3-Carboxylate 586\u003c\/p\u003e \u003cp\u003eSynthesis of Substituted Indazoles via [3+2] Cycloaddition of Benzyne and Diazo Compounds [1H-indazole-3-carboxylic acid,ethylester] 598\u003c\/p\u003e \u003cp\u003eSynthesis of 2,3-Disubstituted Indoles via Palladium-Catalyzed Annulation of Internal Alkynes: 3-Methyl-2- (Trimethylsilyl)Indole 606\u003c\/p\u003e \u003cp\u003eSynthesis of Quinolines by Electrophilic Cyclization of \u003ci\u003eN-(2-Alkynyl)Anilines: 3-Iodo-4-Phenylquinoline 615\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003ePreparation of 4-Spirocyclohexyloxazolidinone by C-H Bond Nitrene Insertion [3-Oxa-1-azaspiro[4.5]decan-2-one] 626\u003c\/p\u003e \u003cp\u003e(S)-5-Pyrrolidin-2-yl-1H-tetrazole 635\u003c\/p\u003e \u003cp\u003eRegioselective C-4 Bromination of Oxazoles: 4-Bromo-5-(thiophen-2-yl)oxazole 648\u003c\/p\u003e \u003cp\u003eThe Preparation of (2R,5S)-2-t-Butyl-3,5-dimethylimidazolidin-4-one 656\u003c\/p\u003e \u003cp\u003eFacile Synthesis of 2-Ethyl-3-quinolinecarboxylic Acid Hydrochloride 667\u003c\/p\u003e \u003cp\u003eSelective Trialkylation of Cyclen with tert-Butyl Bromoacetate [1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, Tri-tert-butylEsterHydrobromide] 673\u003c\/p\u003e \u003cp\u003eDirect Synthesis of Azaheterocycles from N-Aryl\/Vinyl Amides.Synthesis of 4-(Methylthio)-2-phenylquinazoline and 4-(4-Methoxyphenyl)-2-phenylquinoline 677\u003c\/p\u003e \u003cp\u003eDirect Synthesis of 2,5-Dihalosiloles (2,5-Dibromo-1,1-dimethyl-3,4-diphenyl-1H-silole) 688\u003c\/p\u003e \u003cp\u003eLigand-Free Copper(II) Oxide Nanoparticles Catalyzed Synthesis of Substituted Benzoxazoles 697\u003c\/p\u003e \u003cp\u003ePreparation of Chiral and Achiral Triazolium Salts: Carbene Precursors with Demonstrated Synthetic Utility 703\u003c\/p\u003e \u003cp\u003eEnantioselective Preparation of Dihydropyrimidones [(S)-1-Benzyl-6-methyl-2-oxo-4-phenyl-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylicmethylester] 712\u003c\/p\u003e \u003cp\u003e\u003ci\u003eo-Aminobenzaldehyde, Redox-Neutral Aminal Formation and Synthesis of Deoxyvasicinone 726\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003ePd(0)-Catalyzed Diamination of trans-1-Phenyl-1,3-butadiene with Di-tert-Butyldiaziridinone as Nitrogen Source 733\u003c\/p\u003e \u003cp\u003ePd(0)-Catalyzed Asymmetric Allylic and Homoallylic Diamination of 4-Phenyl-1-butene With Di-tert-Butyldiaziridinone 741\u003c\/p\u003e \u003cp\u003eThe Preparation of Indazoles via Metal Free Intramolecular Electrophilic Amination of 2-Aminophenyl Ketoximes 750\u003c\/p\u003e \u003cp\u003eSynthesis of Pyrazolo[1,5-a]Pyridines via Azirines: Preparation of 2-(3-Bromophenyl)-6-(Trifluoromethyl) Pyrazolo[1,5-a]Pyridine 757\u003c\/p\u003e \u003cp\u003ePreparation of 3-Alkylated Oxindoles from N-Benzyl Aniline via a Cu(II)-Mediated Anilide Cyclization Process 766\u003c\/p\u003e \u003cp\u003eGram Scale Catalytic Asymmetric Aziridination: Preparation of (2R,3R)-Ethyl 1-Benzhydryl-3-(4-bromophenyl)aziridine 2-carboxylate 777\u003c\/p\u003e \u003cp\u003ePreparation of Tetrahydroisoquinoline-3-ones Via Cyclization of Phenyl Acetamides Using Eaton ′ sReagent 789\u003c\/p\u003e \u003cp\u003eOne-Pot Conversion of Lactam Carbamates to Cyclic Enecarbamates: Preparation of 1-tert-Butoxycarbonyl-2,3-Dihydropyrrole 797\u003c\/p\u003e \u003cp\u003eCyclohexeneImine(7-Aza-bicyclo[4.1.0]heptane) 803\u003c\/p\u003e \u003cp\u003eDirect Fluorination of the Carbonyl Group of Benzophenones Using Deoxo-Fluor R : Preparation of Bis(4- Fluorophenyl)difluoromethane 810\u003c\/p\u003e \u003cp\u003ePreparation of t-Butyl-3-Bromo-5-Formylbenzoate Through SelectiveMetal-HalogenExchangeReactions 817\u003c\/p\u003e \u003cp\u003eAmide Formation by Decarboxylative Condensation of Hydroxylamines and α-Ketoacids:\u003cbr\u003e \u003ci\u003eN-[(1S)-1-Phenylethyl]benzeneacetamide 826\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eNew, Convenient Route for Trifluoromethylation of Steroidal Molecules 832\u003c\/p\u003e \u003cp\u003eLow Pressure Carbonylation of Epoxides to β-Lactones 841\u003c\/p\u003e \u003cp\u003ePreparation of Cyclobutenone 849\u003c\/p\u003e \u003cp\u003eSafe and Scalable Preparation of Barluenga ′ sReagent (Bis(pyridine)iodonium(I) tetrafluoroborate) 858\u003c\/p\u003e \u003cp\u003eCatalytic Intramolecular Friedel-Crafts Reaction of Benzyl Meldrum ′ s Acid Derivatives: Preparation of 5,6-Dimethoxy-2-methyl-1-indanone 867\u003c\/p\u003e \u003cp\u003eConvenient Synthesis of α-Diazoacetates from α-Bromoacetates and N,N ′ -Ditosylhydrazine: Preparation of Benzyl Diazoacetate 876\u003c\/p\u003e \u003cp\u003eEfficient Synthesis of Oxime Using O-TBS-N-Tosylhydroxylamine: Preparation of (2Z)-4-(Benzyloxy)but-2-enalOxime 883\u003c\/p\u003e \u003cp\u003eProtection of Diols with 4-(tert-Butyldimethylsilyloxy)- benzylidene Acetal and its Deprotection: (4-((4R,5R)-4,5-Diphenyl-1,3-dioxolan-2-yl)phenoxy) (tert-butyl)dimethylsilane 892\u003c\/p\u003e \u003cp\u003eTetrakis(dimethylamino)allene 901\u003c\/p\u003e \u003cp\u003eA Practical Synthesis of Isocyanates from Isonitriles: Ethyl 2-Isocyanatoacetate 909\u003c\/p\u003e \u003cp\u003eSilver-Catalyzed Rearrangement of Propargylic Sulfinates: SynthesisofAllenicSulfones 913\u003c\/p\u003e \u003cp\u003ePreparation of 1-Monoacylglycerols via the Suzuki-Miyaura Reaction: 2,3-Dihydroxypropyl (Z)-tetradec-7-enoate 919\u003c\/p\u003e \u003cp\u003eDibenzo[a,e]cyclooctene: Multi-gram Synthesis of a Bidentate Ligand 934\u003c\/p\u003e \u003cp\u003ePreparationofIsopropyl2-Diazoacetyl(Phenyl)Carbamate 943\u003c\/p\u003e \u003cp\u003ePreparation of Ethyl 1-Benzyl-4-Fluoropiperidine-4-Carboxylate 953\u003c\/p\u003e \u003cp\u003ePreparation and [2+2] Cycloaddition of 1-Triisopropylsiloxy- 1-Hexyne with Methyl Crotonate:\u003c\/p\u003e \u003cp\u003e3-Butyl-4-Methyl-2-Triisopropylsiloxy-Cyclobut-2- EnecarboxylicAcidMethylEster 957\u003c\/p\u003e \u003cp\u003e1,3,5-Triacetylbenzene 965\u003c\/p\u003e \u003cp\u003eAn Efficient and Scalable Ritter Reaction for the Synthesis of t-ButylAmides 972\u003c\/p\u003e \u003cp\u003ePalladium-Catalyzed Dehydrative Allylation of Hypophosphorous Acid with Allylic Alcohols Preparation of Cinnamyl-H-PhosphinicAcid 979\u003c\/p\u003e \u003cp\u003eSynthesis of Tetraorganosilanes: (Chloromethyl)Dimethylphenylsilane 987\u003c\/p\u003e \u003cp\u003eOrganocatalytic α-Methylenation of Aldehydes: Preparation of 3,7-Dimethyl-2-Methylene-6-Octenal 991\u003c\/p\u003e \u003cp\u003ePreparation of Cycloheptane-1,3-Dione via Reductive Ring Expansion of 1-Trimethylsilyloxy-7,7-dichlorobicyclo[3.2.0]heptan-6-one (Cycloheptane-1,3-dione) 997\u003c\/p\u003e \u003cp\u003eSynthesis of Trifluoromethyl Ketones from Carboxylic Acids: 4-(3,4-Dibromophenyl)-1,1,1-trifluoro-4- methylpentan-2-one 1004\u003c\/p\u003e \u003cp\u003eSynthesis of 2-[3,3 ′ -Di-(tert-Butoxycarbonyl)- aminodipropylamine]-4,6,-dichloro-1,3,5-triazine as a Monomer and 1,3,5-[Tris-Piperazine]-triazine as a Core for the Large Scale Synthesis of Melamine (Triazine) Dendrimers 1012\u003c\/p\u003e \u003cp\u003eLarge Scale, Green Synthesis of a Generation-1 Melamine (Triazine)Dendrimer 1020\u003c\/p\u003e \u003cp\u003eSynthesis of Enamides from Ketones: Preparation of \u003ci\u003eN-(3,4-Dihydronaphthalene-1-yl)acetamide 1028\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eThe Direct Acyl-Alkylation of Arynes. Preparation of Methyl 2-(2-Acetylphenyl)acetate 1040\u003c\/p\u003e \u003cp\u003ePreparation of a Trifluoromethyl Transfer Agent: 1-Trifluoromethyl-1,3-Dihydro-3,3-Dimethyl-1,2-Benziodoxole 1049\u003c\/p\u003e \u003cp\u003ePreparation of Horner-Wadsworth-Emmons Reagent: Methyl 2-Benzyloxycarbonylamino-2-(Dimethoxyphosphinyl) acetate 1059\u003c\/p\u003e \u003cp\u003eEnals via a Simple Two-Carbon Homologation of Aldehydes and Ketones 1067\u003c\/p\u003e \u003cp\u003eGold(I)-Catalyzed Decarboxylative Allylic Amination of Allylic\u003cbr\u003e \u003ci\u003eN-Tosylcarbamates 1075\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eSynthesis of Cyclobutarenes by Palladium-Catalyzed C(sp 3)-H Bond Arylation: Preparation of Methyl 7-Methylbicyclo[4.2.0]Octa-1,3,5-Triene-7-Carboxylate 1083\u003c\/p\u003e \u003cp\u003eB-Protected Haloboronic Acids for Iterative Cross-Coupling 1090\u003c\/p\u003e \u003cp\u003eSynthesis of (3-Chlorobutyl)Benzene by the Cobalt-catalyzed Hydrochlorinationof4-Phenyl-1-butene 1104\u003c\/p\u003e \u003cp\u003eCopper-Catalyzed Three-Component Reaction of 1-Alkynes, Sulfonyl Azides, And Water:\u003cbr\u003e \u003ci\u003eN-(4-Acetamidophenylsulfonyl)-2-Phenylacetamide 1109\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eSynthesis of Dimethyl 2-Phenylcyclopropane-1, 1-Dicarboxylate Using an Iodonium Ylide Derived from Dimethyl Malonate 1115\u003c\/p\u003e \u003cp\u003ePalladium (II) Acetate-Butyl Di-1-adamantylphosphine Catalyzed Arylation of Electron-Rich Heterocycles. Preparation of 5-Phenyl-2-isobutylthiazole 1124\u003c\/p\u003e \u003cp\u003eGeneral Method for Copper-Catalyzed Arylation of Acidic AreneC-H Bonds. Preparation of 2-Chloro-5-(3-Methylphenyl)-Thiophene 1131\u003c\/p\u003e \u003cp\u003eRhodium-Catalyzed Enantioselective Addition of Arylboronic Acids to In Situ Generated N-Boc Arylimines Preparation of (S)-tert-Butyl (4-Chlorophenyl)(thiophen-2-yl) methylcarbamate 1138\u003c\/p\u003e \u003cp\u003eSynthesis of 2-Aryl Pyridines by Palladium-Catalyzed Direct ArylationofPyridineN-Oxides 1150\u003c\/p\u003e \u003cp\u003eNickel-Catalyzed Enantioselective Negishi Cross-Couplings of Racemic Secondary α-Bromo Amides with Alkylzinc Reagents: (S)-N-Benzyl-7-cyano-2- ethyl-N-phenylheptanamide 1159\u003c\/p\u003e \u003cp\u003ePalladium-Catalyzed Alkyl-Alkyl Suzuki Cross-Couplings of Primary Alkyl Bromides at Room Temperature: (13-Chlorotridecyloxy)triethylsilane 1166\u003c\/p\u003e \u003cp\u003eSynthesis of Chiral Pyridine Bis(Oxazoline) Ligands for Nickel-Catalyzed Asymmetric Negishi Cross-Couplings of Secondary Allylic Chlorides with Alkylzincs: 2,6-Bis[(4R)-4,5-Dihydro-4-(2-phenylethyl)-2-oxazolyl]- Pyridine 1175\u003c\/p\u003e \u003cp\u003eNickel-catalyzed Asymmetric Negishi Cross-Couplings of Racemic Secondary Allylic Chlorides With Alkylzincs: (S,E)-Ethyl6-(1,3-Dioxolan-2-yl)-4-methylhex-2-enoate 1180\u003c\/p\u003e \u003cp\u003eSynthesis of 2-Substituted Biaryls via Cu\/Pd-Catalyzed Decarboxylative Cross-Coupling of 2-Substituted Potassium Benzoates: 4-Methyl-2 ′ -Nitrobiphenyl and 2-Acetyl-4 ′ -Methylbiphenyl 1191\u003c\/p\u003e \u003cp\u003eα-Arylation of Esters Catalyzed by the Pd(I) Dimer [P(t-Bu) 3 Pd(μ-Br)] 2 1202\u003c\/p\u003e \u003cp\u003eRuthenium-Catalyzed Arylation of Ortho C-H Bond in an Aromatic with an Arylboronate: 8-Phenyl-1-Tetralone 1210\u003c\/p\u003e \u003cp\u003eMagnesiation of Weakly Activated Arenes using tmp 2 Mg⋅2LiCl: Synthesis of tert-ButylEthylPhthalate 1217\u003c\/p\u003e \u003cp\u003eSynthesis of (2R)-3-[[(1,1-Dimethylethyl) dimethylsilyl]oxy]-2-methylpropanal by Rhodium-Catalyzed AsymmetricHydroformylation 1226\u003c\/p\u003e \u003cp\u003eMulticomponent Synthesis of Tertiary Diarylmethylamines: 1-((4-Fluorophenyl)(4- hoxyphenyl)methyl)piperidine 1236\u003c\/p\u003e \u003cp\u003eAnhydrous Hydration of Nitriles to Amides: \u003ci\u003ep-Carbomethoxybenzamide 1246\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eSynthesis of 8,8-Dipropylbicyclo[4.2.0]octa-1,3,5-trien-7-one via Pd-catalyzed Intramolecular C-H Bond-Acylation 1251\u003c\/p\u003e \u003cp\u003eSynthesis of Lithium 2-Pyridyltriolborate and Its Cross-Coupling ReactionwithArylHalides 1261\u003c\/p\u003e \u003cp\u003e(R)-2,2 ′ -Binaphthoyl-(S,S)-di(1-phenylethyl) Aminophosphine Scalable Protocols for the Syntheses of Phosphoramidite (Feringa)Ligands 1267\u003c\/p\u003e \u003cp\u003e(R)-3-Methyl-3-Phenyl-1-Pentene Via Catalytic Asymmetric Hydrovinylation 1275\u003c\/p\u003e \u003cp\u003eSynthesis of Aminoarenethiolato-Copper(I) Complexes 1291\u003c\/p\u003e \u003cp\u003eThe Preparation of Cyclohept-4-enones by Rhodium-Catalyzed Intermolecular [5+2]Cycloaddition 1299\u003c\/p\u003e \u003cp\u003eBenzyl Alcohol as an Alkylating Agent Using the Ruthenium-CatalyzedBorrowingHydrogenStrategy 1309\u003c\/p\u003e \u003cp\u003ePalladium-Catalyzed Cross-Coupling Using an Air-Stable Trimethylaluminum Source. Preparation of Ethyl4-Methylbenzoate 1315\u003c\/p\u003e \u003cp\u003eOne-Pot Diazotization and Heck Reaction of Methyl Anthranilate:-(3-Oxopropyl)benzoicAcidMethylEster 1325\u003c\/p\u003e \u003cp\u003eDiphenyldiazomethane 1329\u003c\/p\u003e \u003cp\u003eAllylic Oxidation Catalyzed by Dirhodium(II) Tetrakis[ϵcaprolactamate] of tert-Butyldimethylsilyl-protected \u003ci\u003etrans-Dehydroandrosterone 1335\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2-Iodoxy-5-Methylbenzenesulfonic Acid-Catalyzed Selective Oxidation of 4-Bromobenzyl Alcohol to 4-Bromobenzaldehyde or 4-Bromobenzoic Acid with Oxone 1348\u003c\/p\u003e \u003cp\u003eEnantioselective Oxidation of an Alkyl Aryl Sulfide: Synthesis of (S)-(–)-Methyl p-Bromophenyl Sulfoxide 1356\u003c\/p\u003e \u003cp\u003e\u003ci\u003etert-Butyl tert-Butyldimethylsilylglyoxylate: A Useful Conjunctive Reagent 1363\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eMild and Efficient One-Pot Curtius Rearrangement: Preparation of \u003ci\u003eN-tert-ButylAdamantanyl-1-yl-carbamate 1370\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eThe Preparation of Amides by Copper-Mediated Oxidative Coupling of Aldehydes and Amine Hydrochloride Salts 1376\u003c\/p\u003e \u003cp\u003eEfficient One-Pot Synthesis of Bis(4-tert-Butylphenyl)iodonium Triflate 1382\u003c\/p\u003e \u003cp\u003eSynthesis of Et 2 SBr SbCl 5 Br and Its Use in Biomimetic BrominativePolyeneCyclizations 1388\u003c\/p\u003e \u003cp\u003eStereoselective Synthesis of (E)-2,3-Dibromobut-2-enoic Acid 1402\u003c\/p\u003e \u003cp\u003eMetal-Free One-Pot Oxidative Amination of Aromatic Aldehydes: Conversion of Benzaldehyde to N-Benzoyl Pyrrolidine 1407\u003c\/p\u003e \u003cp\u003eA Practical And Scalable Synthesis of N-Halo Compounds: 2-Chloro-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 1413\u003c\/p\u003e \u003cp\u003eMild Conversion of Tertiary Amides to Aldehydes Using Cp 2 Zr(H)Cl (Schwartz ′ sReagent) 1420\u003c\/p\u003e \u003cp\u003ePreparation of (3,5-Dimethoxy-1-phenyl-cyclohexa-2,5-dienyl)-acetonitrile through Birch Reductive Alkylation(BRA) 1429\u003c\/p\u003e \u003cp\u003ePreparation of N-Isopropylidene-N ′ -2-Nitrobenzenesulfonyl Hydrazine (IPNBSH) and Its Use in Palladium–catalyzed Synthesis of Monoalkyl Diazenes. Synthesis of 9-Allylanthracene 1437\u003c\/p\u003e \u003cp\u003eSynthesis of Spiroborate Esters from 1,2-Aminoalcohols, Ethylene Glycol and Triisopropyl Borate: Preparation of (S)-1-(1,3,2-Dioxaborolan-2-yloxy)-3-methyl-1, 1-diphenylbutan-2-amine 1449\u003c\/p\u003e \u003cp\u003eCatalytic Enantioselective Borane Reduction of Benzyl Oximes: Preparation of (S)-1-Pyridin-3-yl-ethylamine Bis-hydrochloride 1458\u003c\/p\u003e \u003cp\u003eReductive Radical Decarboxylation of Aliphatic CarboxylicAcids 1473\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCharles Zercher\u003c\/b\u003e earned a BA in Chemistry at Messiah College in Grantham, PA. His graduate education initiated with studies in Medicinal Chemistry at the State University of New York at Buffalo leading to an MS degree in 1985. He received a Ph.D. in Chemistry at the University of Notre Dame 1989 where he studied under the direction of Marvin Miller. Following post-doctoral studies in the laboratory of Paul Wender at Stanford University, Chuck joined the faculty at the University of New Hampshire. He was awarded the University of New Hampshire's Outstanding Assistant Professor Award in 1996 and was promoted to Professor in 2003. His teaching interests include synthetic methods and strategies, organic spectroscopy, and introductory organic chemistry.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989733097701,"sku":"NP9781118117828","price":224.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781118117828.jpg?v=1761785291","url":"https:\/\/k12savings.com\/products\/organic-syntheses-collective-volume-12-isbn-9781118117828","provider":"K12savings","version":"1.0","type":"link"}