{"product_id":"organic-reactions-volume-76-isbn-9780470638439","title":"Organic Reactions, Volume 76","description":"Volume 76 in the venerable \u003ci\u003eOrganic Reactions\u003c\/i\u003e series comprises three chapters that cover the ever-increasing emphasis of transition metal catalysis in organic synthesis. These three chapters represent some of the most important transformations that enable the construction of carbon-carbon bonds, heterocycles and carbon-heteratom bonds. This volume features a comprehensive treatment of transition metal (palladium, nickel, copper) catalyzed a-arylation of enolates derived from many common functional groups such as ketones, aldehydes, esters and nitriles (Prim, Marque, Gaucher, Campagne) including enantioselective variants; palladium catalyzed cyclization to form indoles (Cacchi, Fabrizi, Goggiamani) one of the most prevalent and important classes of heterocycles in natural products and pharmaceutical agents; and an overview of a newly developed dihydroxylation reaction of alkenes (Donohoe, Bataille, Innocenti) that uses hydrogen bonding interactions to direct the delivery of an osmium catalyst with high selectivity. As with all \u003ci\u003eOrganic Reactions\u003c\/i\u003e chapters, these reviews emphasize the preparative aspects of the featured transformation and contain comprehensive compilations of all known examples in the tables.  1. HYDROGEN-BONDING-MEDIATED DIRECTED OSMIUM DIHYDROXYLATION\u003cbr\u003e \u003ci\u003eTimothy J. Donohoe, Carole J. R. Bataille, and Paolo Innocenti\u003c\/i\u003e1  \u003cp\u003e2. TRANSITION-METAL-CATALYZED α-ARYLATION OF ENOLATES\u003cbr\u003e \u003ci\u003eDamien Prim, Sylvain Marque, Anne Gaucher, and Jean-Marc Campagne \u003c\/i\u003e 49\u003c\/p\u003e \u003cp\u003e3. INDOLES VIA PALLADIUM-CATALYZED CYCLIZATION\u003cbr\u003e \u003ci\u003eSandro Cacchi, Giancarlo Fabrizi, and Antonella Goggiamani \u003c\/i\u003e 281\u003c\/p\u003e \u003cp\u003eCUMULATIVE CHAPTER TITLES BY VOLUME535\u003c\/p\u003e \u003cp\u003eAUTHOR INDEX, VOLUMES 1–76  551\u003c\/p\u003e \u003cp\u003eCHAPTER AND TOPIC INDEX, VOLUMES 1–76  557\u003c\/p\u003e \u003cb\u003eScott E. Denmark\u003c\/b\u003e received his undergraduate degree from the Massachusetts Institute of Technology in 1975 and his graduate degree (D.Sc. Tech.) from the ETH-Zürich in 1980. He joined the faculty at Illinois in the same year. His research interests are in structural, synthetic and mechanistic organic chemistry.","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989731590373,"sku":"NP9780470638439","price":200.75,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470638439.jpg?v=1761785284","url":"https:\/\/k12savings.com\/products\/organic-reactions-volume-76-isbn-9780470638439","provider":"K12savings","version":"1.0","type":"link"}