{"product_id":"neuroendocrine-disorders-in-children-isbn-9781909962507","title":"Neuroendocrine Disorders in Children","description":"\u003cp\u003eImpairments in the interaction between the central nervous system and the endocrine system can lead to a number of disorders in children.  These include type 1 diabetes, growth disorders, adrenal thyroid and pituitary problems, Addison’s disease and Cushing syndrome, among others.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eNeuroendocrine Disorders in Children\u003c\/i\u003e provides a comprehensive examination of paediatric and adolescent disorders focusing on the basic science and its clinical relevance. Complex issues are discussed in an easy-to-follow manner and the latest developments in the area are reviewed.\u003c\/p\u003e \u003cp\u003eThis volume will become invaluable reading for paediatric endocrinologists, paediatric and adult neurologists and trainee paediatricians.\u003c\/p\u003e \u003cp\u003eSections in the book cover\u003c\/p\u003e \u003cul\u003e \u003cli\u003eThe GH-IGF1 axis and the brain\u003c\/li\u003e \u003cli\u003eThe thyroid axis and the brain\u003c\/li\u003e \u003cli\u003eRegulation of appetite and weight\u003c\/li\u003e \u003cli\u003eEffects of treatment of cancer on the neuroendocrine system\u003c\/li\u003e \u003cli\u003eAdrenal disorders and the brain\u003c\/li\u003e \u003cli\u003eNeuroendocrinology and the reproductive axis\u003c\/li\u003e \u003cli\u003eNeurological complications of diabetes mellitus\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eSection 1: The GH-IGF1 axis and the brain\u003cbr\u003e\u003cbr\u003e1. Normal hypothalamo-pituitary function and the neuroendocrine regulation of growth,\u003cbr\u003e\u003cbr\u003e2. Disorders of the GH-IGF1 axis leading to growth failure,\u003cbr\u003e\u003cbr\u003e3.   The effect of growth hormone on the brain\u003cbr\u003e\u003cbr\u003e4. Impact of disorders of the GH-IGF1 axis on neurological functioning  in childhood\u003cbr\u003e\u003cbr\u003e5. Neuroencocrine Disorders of salt and water balance\u003c\/p\u003e \u003cp\u003eSection 2:  The thyroid axis and the brain\u003cbr\u003e\u003cbr\u003e6. The hypothalamic-pituitary-thyroid axis: anatomy and physiology\u003cbr\u003e\u003cbr\u003e7.    Disorders of the hypothalamo-pituitary-thyroid\u003cbr\u003e\u003cbr\u003e8.       Impact of Thyroid Disorders on Neurological Function\u003c\/p\u003e \u003cp\u003eSection 3: Regulation of appetite and weight\u003cbr\u003e\u003cbr\u003e9.   The role of the hypothalamus in normal weight regulation\u003cbr\u003e\u003cbr\u003e10.  Genetic childhood obesity syndromes\u003cbr\u003e\u003cbr\u003e11. Treatment of Obesity\u003c\/p\u003e \u003cp\u003eSection 4: Effects of treatment of cancer on the neuroendocrine system\u003cbr\u003e\u003cbr\u003e12. Late effects of cancer and its treatments on the neuroendocrine system,\u003cbr\u003e\u003cbr\u003e13. Craniopharyngioma\u003c\/p\u003e \u003cp\u003eSection 5: Adrenal disorders and the brain\u003cbr\u003e\u003cbr\u003e15. The hypothalamo-pituitary-adrenal axis and its regulation\u003cbr\u003e\u003cbr\u003e16.  The effect of stress on the hypothalamic-pituitary-adrenal axis: an update\u003cbr\u003e\u003cbr\u003e17.  Adrenoleukodystrophy- neurological aspects\u003cbr\u003e\u003cbr\u003e18.   Cushing disease: diagnosis and management\u003c\/p\u003e \u003cp\u003eSection 6: Neuroendocrinology and the reproductive axis\u003cbr\u003e\u003cbr\u003e19.   The hypothalamic-pituitary-gonadal axis\u003cbr\u003e\u003cbr\u003e20.    Disorders of gonadotrophin secretion Hypogonadotrophic  hypogonadism\u003cbr\u003e\u003cbr\u003e21   Precocious puberty \u003cbr\u003e\u003cbr\u003e22.   Psychological and behavioural consequences of gonadal hormone abnormality during early development\u003c\/p\u003e \u003cp\u003eSection 7 Neurological complications of diabetes mellitus\u003cbr\u003e\u003cbr\u003e23. Diabetes and the developing brain\u003cbr\u003e\u003cbr\u003e24.  The Central actions of insulin\u003c\/p\u003e \u003cp\u003e\u003cb\u003eProfessor Mehul Dattani MBBS, DCH, FRCPCH, MD\u003c\/b\u003e leads paediatric and adolescent endocrinology at Great Ormond Street Hospital for Children, London. His research interests are in the area of growth, pituitary development and disorders of puberty. Professor Dattani has received a number of national and international awards for his research work. He is currently Chair of the Programme Organizing Committee of the European Society for Paediatric Endocrinology.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eProfessor Peter Hindmarsh BSc, MD, FRCP, FRCPCH\u003c\/b\u003e is Professor of Paediatric Endocrinology at University College London and Divisional Clinical Director at the University College London Hospitals. His research interests include mathematical modelling of feedback systems including growth hormone, cortisol and insulin. He served as Chair of the working party on diabetes whose work led to major improvements in paediatric diabetes care in the UK.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eProfessor Iain Robinson MBE, MA, DPhil, FMedSci, HonFBPhS\u003c\/b\u003e was head of the Division of Molecular Neuroendocrinology at the Medical Research Council National Institute for Medical Research until retirement in 2009. A major focus of interest was the study of hypothalmo-pituitary defects that cause growth retardation in children. His is group pioneered microsampling techniques in experimental animals and neonates, as well as developing novel transgenic and imaging techniques.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eDr Lucinda Carr MB, ChB, FRCPCH, MD\u003c\/b\u003e is Consultant Paediatric Neurologist at Great Ormond Street Hospital for Children, London, working across the departments of neurology and neurodisability. She served as the clinical lead in neurology at the hospital from 2008 to 2013. Dr Carr's main research interest is in movement disorders and cerebral palsy and she was a member of the team that developed the NICE guidelines on the management of spasticity in children.\u003c\/p\u003e","brand":"Mac Keith Press","offers":[{"title":"Default Title","offer_id":47989683159269,"sku":"NP9781909962507","price":103.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781909962507.jpg?v=1761785089","url":"https:\/\/k12savings.com\/products\/neuroendocrine-disorders-in-children-isbn-9781909962507","provider":"K12savings","version":"1.0","type":"link"}