{"product_id":"neurodegeneration-isbn-9780470672686","title":"Neurodegeneration","description":"This book unites the diverse range of complex neurodegenerative diseases into a textbook designed for clinical practice, edited by globally leading authorities on the subject.\u003cbr\u003e \u003cul\u003e \u003cli\u003ePresents a clinically oriented guide to the diseases caused by neurodegeneration \u003c\/li\u003e \u003cli\u003eTemplated chapters combine clinical and research information on neurodegenerative diseases beginning with the common elements before treating each disease individually\u003c\/li\u003e \u003cli\u003eDiseases are grouped by anatomical regions of degeneration and include common disorders such as Parkinson’s Disease, Alzheimer’s Disease, Amyotrophic Lateral Sclerosis\/Motor Neuron Disease, and Multiple Sclerosis as well as less common diseases \u003c\/li\u003e \u003cli\u003eEdited by globally leading authorities on the subject, and written by expert contributing authors\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eList of Contributors, vi\u003c\/p\u003e \u003cp\u003ePreface, ix\u003c\/p\u003e \u003cp\u003eDedication, x\u003c\/p\u003e \u003cp\u003e1 Pathology of Brain Aging, 1\u003cbr\u003e\u003ci\u003eJanna H. Neltner and Peter T. Nelson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Protein Aggregation and Neurodegeneration: Tauopathies and Synucleinopathies, 12\u003cbr\u003e\u003ci\u003eMichel Goedert\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Prion Degeneration, 25\u003cbr\u003e\u003ci\u003eJames A. Mastrianni\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Excitotoxicity, 37\u003cbr\u003e\u003ci\u003eMark P. Mattson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Etiology and Pathogenesis of Parkinson Disease, 46\u003cbr\u003e\u003ci\u003eRuth-Mary deSouza and Anthony H.V. Schapira\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Parkinson Disease: Treatment Options – Surgical Therapy, 53\u003cbr\u003e\u003ci\u003eTravis S. Tierney and Andres M. Lozano\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Multiple System Atrophy: Clinical, Genetics, and Neuropathology, 58\u003cbr\u003e\u003ci\u003eLucia V. Schottlaender, Anna Sailer, Zeshan Ahmed, Dennis W. Dickson, Henry Houlden, and Owen A. Ross\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Progressive Supranuclear Palsy, 72\u003cbr\u003e\u003ci\u003eHuw R. Morris\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Dementia with Lewy Bodies, 83\u003cbr\u003e\u003ci\u003eRodolfo Savica and David S. Knopman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Corticobasal Degeneration, 93\u003cbr\u003e\u003ci\u003eKeith A. Josephs, Jr.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Alzheimer’s Disease, 102\u003cbr\u003e\u003ci\u003eQurat ul Ain Khan and Neill R. Graff-Radford\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 Frontotemporal Dementia, 115\u003cbr\u003e\u003ci\u003eChristian W. Wider, Barbara Jasinska-Myga, Takuya Konno, and Zbigniew K. Wszolek\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Prion Diseases and Other Rapidly Progressive Dementias, 126\u003cbr\u003e\u003ci\u003eEric Eggenberger and Daniel L. Murman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis, 137\u003cbr\u003e\u003ci\u003eKevin B. Boylan, Mark A. Ross, and Eric J. Sorenson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Hereditary Spastic Paraplegia, 161\u003cbr\u003e\u003ci\u003ePawel P. Liberski and Craig Blackstone\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16 Spinal Muscular Atrophy, 179\u003cbr\u003e\u003ci\u003eJoseph R. Wooley, Melissa E. Crowder, Noah J. Pyles, and Charlotte J. Sumner\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17 Spinal and Bulbar Muscular Atrophy (Kennedy Disease), 202\u003cbr\u003e\u003ci\u003eErich Peter Bosch\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18 Optic Neuropathies, 211\u003cbr\u003e\u003ci\u003eDesmond Kidd\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e19 Peripheral Nerve Neuropathies Including Charcot–Marie–Tooth Disease, 218\u003cbr\u003e\u003ci\u003eAmelie Pandraud and Henry Houlden\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e20 Axonal Loss and Neurodegeneration in Multiple Sclerosis, 238\u003cbr\u003e\u003ci\u003eRanjan Dutta, Jacqueline Chen, Nobuhiko Ohno, Daniel Ontaneda, and Bruce D. Trapp\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e21 Huntington’s Disease and Other Choreas, 248\u003cbr\u003e\u003ci\u003eSalman Haider, Edward Wild, and Sarah J. Tabrizi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e22 Spinocerebellar Ataxias, 284\u003cbr\u003e\u003ci\u003eH. Brent Clark and Harry T. Orr\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e23 Ataxia Telangiectasia, 296\u003cbr\u003e\u003ci\u003eMalcolm Taylor\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e24 Niemann–Pick Disease, 303\u003cbr\u003e\u003ci\u003eMarc C. Patterson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e25 X-linked Adrenoleukodystrophy, 309\u003cbr\u003e\u003ci\u003eDeborah L. Renaud\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e26 Neurodegeneration with Brain Iron Accumulation, Wilson Disease, and Manganism, 317\u003cbr\u003e\u003ci\u003eAlisdair McNeill\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex, 327\u003c\/p\u003e \u003cp\u003e\u003cb\u003eAbout the Editors\u003c\/b\u003e\u003cbr\u003e \u003cb\u003eProfessor Anthony Schapira\u003c\/b\u003e is Professor of Neurological Science and Head of the Department of Clinical Neuroscience at the UCL Institute of Neurology, London, UK and Chairman of Clinical Neurosciences Specialties.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eZbigniew Wszolek\u003c\/b\u003e, MD, is Professor of Neurology in the Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eTed M.Dawson\u003c\/b\u003e, MD, PhD, is Leonard and Madlyn Abramson Professor of Neurodegenerative Diseases and Scientific Director in the Institute for Cell Engineering, Johns Hopkins University, Baltimore, Maryland, USA.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eProfessor Nicholas Wood\u003c\/b\u003e is Research Director of the UCL Institute of Genetics and Galton Professor of Genetics at UCL National Hospital for Neurology and Neurosurgery, Institute of Neurology, London, UK.\u003c\/p\u003e \u003cp\u003eGiven the aging population of the developed world, and the increasing survival rates from traditional diseases such as cancer, the numbers of patients suffering from neurodegenerative diseases is increasing. Not only do these diseases inflict pain and emotional toil on their sufferers and their families, they also require years of costly health care\u003c\/p\u003e \u003cp\u003eMany of the neurodegenerative diseases have been considered within more traditional domains of neurology, such as movement disorders or behavioral neurology. However, there is increasing recognition that this symptom-based classification does not correspond to underlying pathologies for which evidence of similarity is emerging.\u003c\/p\u003e \u003cp\u003eThis book draws together clinical and research information on neurodegenerative diseases, beginning with the common elements before treating each disease individually using a standard template. Uniquely diseases will be grouped by anatomical regions of degeneration – which are largely but not exclusively related to symptomatic considerations.\u003c\/p\u003e \u003cp\u003eGeneral chapter topics cover what can be considered normal aging versus neurodegenerative diseases, and discuss the initial indications of neurodegeneration progression of symptoms. Diagnostic guidelines include how to apply cognitive examinations, movement examinations, and lab and imaging investigations to reach a diagnosis – an often very complex process in neurodegenerative disease. Also discussed are patient health care issues, and the effect on carers and families, and palliative and end-of-life care.\u003c\/p\u003e \u003cp\u003eKey Features\u003c\/p\u003e \u003cul\u003e \u003cli\u003ePresents a clinically oriented guide to the diseases caused by neurodegeneration\u003c\/li\u003e \u003cli\u003eIncludes templated chapters with helpful pedagogy\u003c\/li\u003e \u003cli\u003eGroups diseases by anatomical regions of degeneration, including common disorders such as Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis\/motor neuron disease, and multiple sclerosis as well as less common diseases\u003c\/li\u003e \u003cli\u003eOffers expert advice from globally leading authorities on the subject\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003eThis book will be of use to neurologists, and will be of interest to neuropsychiatrists who deal with psychiatric aspects of neurological disease. It will also be relevant to neuroscientists who need to know more of the clinical aspects of the conditions they are working on.\u003c\/p\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47989682831589,"sku":"NP9780470672686","price":252.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470672686.jpg?v=1761785090","url":"https:\/\/k12savings.com\/products\/neurodegeneration-isbn-9780470672686","provider":"K12savings","version":"1.0","type":"link"}