{"product_id":"neocortical-neurogenesis-in-development-and-evolution-isbn-9781119860808","title":"Neocortical Neurogenesis in Development and Evolution","description":"\u003cb\u003eNEOCORTICAL NEUROGENESIS IN DEVELOPMENT AND EVOLUTION\u003c\/b\u003e \u003cp\u003e\u003cb\u003eUnderstanding the development and evolution of the mammalian neocortex\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eThe development of the mammalian brain, including the human brain, is inextricably linked with its evolution. Of particular interest is the development of the neocortex, the youngest part of the cerebral cortex in evolutionary terms and the seat of such vital functions as sensory perception, generation of motor commands, and higher-order cognition. The process of neurogenesis is crucial to the formation and function of the neocortex, but this process is complex, based on species-specific adaptations of old and acquired new traits that subserve specific functions introduced during mammalian evolution. \u003c\/p\u003e\u003cp\u003e\u003ci\u003eNeocortical Neurogenesis in Development and Evolution\u003c\/i\u003e provides a groundbreaking and comprehensive overview of neurogenesis in the developing neocortex and its evolutionary implications. It covers the generation of neurons and their migration to their functional positions, neural patterning, cortical folding, and variations and malformations of cortical development.  \u003c\/p\u003e\u003cp\u003eReaders will find: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eA comprehensive review of the evolution and development of the neocortex in mammals — the part of our brain involved in the higher cognitive functions\u003c\/li\u003e \u003cli\u003eA multitude of subject disciplines ranging from neuroscience, molecular biology, genetics, developmental biology, evolutionary biology and medicine to provide a holistic understanding of the evolutionary youngest part of the cerebral cortex\u003c\/li\u003e \u003cli\u003eCoverage of neurogenesis in the developing neocortex and how this contributes to our understanding of the evolutionary implications\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003e\u003ci\u003eNeocortical Neurogenesis in Development and Evolution\u003c\/i\u003e is essential for researchers and postgraduates in neuroscience, developmental biology, evolutionary biology, and medical research. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eCortical Progenitors and Germinal Zones\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Neural stem cells as glia.\u003c\/p\u003e \u003cp\u003e2 Diversity and evolution of human cortical progenitor cell types.\u003c\/p\u003e \u003cp\u003e3 Intermediate progenitors in neocortical development and evolution.\u003c\/p\u003e \u003cp\u003e4 Area V1 development, a model system to link corticogenesis to adult cortex structure and function?\u003c\/p\u003e \u003cp\u003e5 Neocortical neurogenesis in amniote evolution.\u003c\/p\u003e \u003cp\u003e6 Dynamic transcriptional control of neural stem cells.\u003c\/p\u003e \u003cp\u003e7 Mechanical and physical interactions involving neocortical progenitor cells.\u003c\/p\u003e \u003cp\u003e8 The role of human-specific genes and amino acid substitutions for neocortex expansion and modern human vs. Neanderthal differences in neocortical neurogenesis.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eProgenitor Lineages\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9 Temporal scaling: a link between conserved neurogenic processes and differential size in mammalian cortical development.\u003c\/p\u003e \u003cp\u003e10 Interplay of cell-autonomous gene function and tissue-wide mechanisms regulating radial glial progenitor lineage progression.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eGeneration of Neuron Types\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11 Generation of projection neuron diversity in the neocortex: from embryos to organoids.\u003c\/p\u003e \u003cp\u003e12 Development of cortical neuron heterogeneity and impact of neurodevelopmental disorders.\u003c\/p\u003e \u003cp\u003e13 Developmental and evolutionary origins of cortical projection neuron identity and connectivity.\u003c\/p\u003e \u003cp\u003e14 Intrinsic and input-dependent development of cortical neuron types.\u003c\/p\u003e \u003cp\u003e15 Corpus callosum evolution and development.\u003c\/p\u003e \u003cp\u003e16 Towards the transcriptionally-based classification of L6b in the adult mouse brain.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eNeuron Migration\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e17 Cortical neuron migration in health and disease.\u003c\/p\u003e \u003cp\u003e18 The emerging roles of LIS1 biomechanics in cellular and cortical homeostasis.\u003c\/p\u003e \u003cp\u003eNeural Patterning, Specification of Cortical Regions\u003c\/p\u003e \u003cp\u003e19 Understanding human forebrain morphogenesis and early expansion using organoids.\u003c\/p\u003e \u003cp\u003e20 Early neuronal differentiation\/patterning of the human pallium, modeling by in vitro systems, and disruption in developmental disorders.\u003c\/p\u003e \u003cp\u003e21 Mammalian cortical regional specification.\u003c\/p\u003e \u003cp\u003e22 Development of the neocortical area map.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCortical Folding\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e23 Old models know wrinkles best -- A critical review on the mechanisms of cortical gyrification\u003c\/p\u003e \u003cp\u003e24 Investigation of the mechanisms underlying the development and evolution of the cerebral cortex using gyrencephalic ferrets.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCortical Development: Variations, Disorders and Malformations\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e25 Genetic variation altering cortical progenitor function leads to human brain evolution and interindividual differences in human brain structure.\u003c\/p\u003e \u003cp\u003e26 Human neocortical evolution and neurological disorders\u003c\/p\u003e \u003cp\u003e27 Clinical and molecular overview of cortical malformations.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eOverarching Topics\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e28 Post-transcriptional control of brain development.\u003c\/p\u003e \u003cp\u003e29 Regulation of mRNA localization and translation in brain development: Implications for the mechanism leading to the brain evolution and pathogenesis.\u003c\/p\u003e \u003cp\u003e30 The roles of signal transduction during cortical neurogenesis.\u003c\/p\u003e \u003cp\u003e31 Centrosome regulation and function in the developing neocortex.\u003c\/p\u003e \u003cp\u003e32 Keeping the cortex afloat: Cerebrospinal fluid contributions to cerebral cortical development.\u003c\/p\u003e \u003cp\u003e33 Comparative cognitive neuroscience and dorsal and ventral streams in primates.\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eWieland B. Huttner, MD,\u003c\/b\u003e is a Founding Director of the Max Planck Institute of Molecular Cell Biology and Genetics and Honorary Professor at the \u003ci\u003eTechnische Universität Dresden\u003c\/i\u003e, Germany. He has been Chair of Neurobiology of Heidelberg University, Research Group Leader at the European Molecular Biology Laboratory (EMBL) in Heidelberg, and has published key contributions on the cell biology of brain development and its evolutionary implications.   \u003c\/p\u003e\u003cp\u003e\u003cb\u003eUnderstanding the development and evolution of the mammalian neocortex\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eThe development of the mammalian brain, including the human brain, is inextricably linked with its evolution. Of particular interest is the development of the neocortex, the youngest part of the cerebral cortex in evolutionary terms and the seat of such vital functions as sensory perception, generation of motor commands, and higher-order cognition. The process of neurogenesis is crucial to the formation and function of the neocortex, but this process is complex, based on species-specific adaptations of old and acquired new traits that subserve specific functions introduced during mammalian evolution. \u003c\/p\u003e\u003cp\u003e\u003ci\u003eNeocortical Neurogenesis in Development and Evolution\u003c\/i\u003e provides a groundbreaking and comprehensive overview of neurogenesis in the developing neocortex and its evolutionary implications. It covers the generation of neurons and their migration to their functional positions, neural patterning, cortical folding, and variations and malformations of cortical development.  \u003c\/p\u003e\u003cp\u003eReaders will find: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eA comprehensive review of the evolution and development of the neocortex in mammals — the part of our brain involved in the higher cognitive functions\u003c\/li\u003e \u003cli\u003eA multitude of subject disciplines ranging from neuroscience, molecular biology, genetics, developmental biology, evolutionary biology and medicine to provide a holistic understanding of the evolutionary youngest part of the cerebral cortex\u003c\/li\u003e \u003cli\u003eCoverage of neurogenesis in the developing neocortex and how this contributes to our understanding of the evolutionary implications\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003e\u003ci\u003eNeocortical Neurogenesis in Development and Evolution\u003c\/i\u003e is essential for researchers and postgraduates in neuroscience, developmental biology, evolutionary biology, and medical research.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989679718629,"sku":"NP9781119860808","price":225.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781119860808.jpg?v=1761785076","url":"https:\/\/k12savings.com\/products\/neocortical-neurogenesis-in-development-and-evolution-isbn-9781119860808","provider":"K12savings","version":"1.0","type":"link"}