{"product_id":"nanoparticulate-drug-delivery-systems-isbn-9781118148877","title":"Nanoparticulate Drug Delivery Systems","description":"\u003cp\u003e\u003cb\u003e\u003ci\u003eFrank discussions of opportunities and challenges point the way to new, more effective drug delivery systems\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eInterest in nanomedicine has grown tremendously, fueled by the expectation that continued research will lead to the safe, efficient, and cost-effective delivery of drugs or imaging agents to human tissues and organs. The field, however, has faced several challenges attempting to translate novel ideas into clinical benefits. With contributions from an international team of leading nanomedicine researchers, this book provides a practical assessment of the possibilities and the challenges of modern nanomedicine that will enable the development of clinically effective nanoparticulate drug delivery products and systems.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eNanoparticulate Drug Delivery Systems\u003c\/i\u003e focuses on the rationales and preclinical evaluation of new nanoparticulate drug carriers that have yet to be thoroughly reviewed in the literature. The first chapter sets the stage with a general overview of targeted nanomedicine. The book then explores new and promising nanoparticulate drug delivery systems, including:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eLipid nanoparticles for the delivery of nucleic acids\u003c\/li\u003e \u003cli\u003eMultifunctional dendritic nanocarriers\u003c\/li\u003e \u003cli\u003ePolymer drug nanoconjugates\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eNext, the book presents new opportunities and challenges for nanoparticulate drug delivery systems, including:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eClearance of nanoparticles during circulation\u003c\/li\u003e \u003cli\u003eDrug delivery strategies for combatting multiple drug resistance\u003c\/li\u003e \u003cli\u003eToxicological assessment of nanomedicine\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eChapters offer state-of-the-technology reviews with extensive references to facilitate further investigation. Moreover, each chapter concludes with an expert assessment of remaining challenges, pointing the way to solutions and new avenues of research.\u003c\/p\u003e \u003cp\u003eWith its frank discussions of opportunities and challenges, \u003ci\u003eNanoparticulate Drug Delivery Systems\u003c\/i\u003e sets a solid foundation for new research leading to the discovery and development of better nanomedicines.\u003c\/p\u003e  \u003cp\u003ePreface vii\u003c\/p\u003e \u003cp\u003eContributors ix\u003c\/p\u003e \u003cp\u003e1 Tumor-Targeted Nanoparticles: State-of-the-Art and Remaining Challenges 1\u003cbr\u003e  \u003ci\u003eGaurav Bajaj and Yoon Yeo\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Applications of Ligand-Engineered Nanomedicines 21\u003cbr\u003e  \u003ci\u003eGayong Shim, Joo Yeon Park, Lee Dong Roh, Yu-Kyoung Oh, and Sangbin Lee\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Lipid Nanoparticles for the Delivery of Nucleic Acids 51\u003cbr\u003e  \u003ci\u003eYuhua Wang and Leaf Huang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Photosensitive Liposomes as Potential Targeted Therapeutic Agents 81\u003cbr\u003e  \u003ci\u003eDavid H. Thompson, Pochi Shum, Oleg V. Gerasimov, and Marquita Qualls\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Multifunctional Dendritic Nanocarriers: The Architecture and Applications in Targeted Drug Delivery 101\u003cbr\u003e  \u003ci\u003eRyan M. Pearson, Jin Woo Bae, and Seungpyo Hong\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Chitosan-Based Nanoparticles for Biomedical Applications 129\u003cbr\u003e  \u003ci\u003eHeebeom Koo, Kuiwon Choi, Ick Chan Kwon, and Kwangmeyung Kim\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Polymer–Drug Nanoconjugates 151\u003cbr\u003e  \u003ci\u003eRong Tong, Li Tang, Nathan P. Gabrielson, Qian Yin, and Jianjun Cheng\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Nanocrystals Production, Characterization, and Application for Cancer Therapy 183\u003cbr\u003e  \u003ci\u003eChristin P. Hollis and Tonglei Li\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Clearance of Nanoparticles During Circulation 209\u003cbr\u003e  \u003ci\u003eSeung-Young Lee and Ji-Xin Cheng\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Drug Delivery Strategies for Combating Multiple Drug Resistance 241\u003cbr\u003e  \u003ci\u003eJoseph W. Nichols and You Han Bae\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Intracellular Trafficking of Nanoparticles: Implications for Therapeutic Efficacy of the Encapsulated Drug 261\u003cbr\u003e  \u003ci\u003eLin Niu and Jayanth Panyam\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 Toxicological Assessment of Nanomedicine 281\u003cbr\u003e  \u003ci\u003eHayley Nehoff, Sebastien Taurin, and Khaled Greish\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 307\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eYOON YEO, PhD,\u003c\/b\u003e is Assistant Professor of Industrial and Physical Pharmacy at the College of Pharmacy at Purdue University. She also holds a joint appointment as Assistant Professor at Purdue's Weldon School of Biomedical Engineering. Her research focuses on nanoparticle surface engineering for drug delivery to solid tumors, inhalable drug\/gene delivery for cystic fibrosis therapy, and functional biomaterials based on carbohydrates. Dr. Yeo is the recipient of the NSF CAREER Award as well as New Investigator awards from both the American Association of Pharmaceutical Scientists and the American Association of Colleges of Pharmacy.\u003c\/p\u003e  \u003cp\u003e\u003cb\u003e\u003ci\u003eFrank discussions of opportunities and challenges point the way to new, more effective drug delivery systems\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eInterest in nanomedicine has grown tremendously, fueled by the expectation that continued research will lead to the safe, efficient, and cost-effective delivery of drugs or imaging agents to human tissues and organs. The field, however, has faced several challenges attempting to translate novel ideas into clinical benefits. With contributions from an international team of leading nanomedicine researchers, this book provides a practical assessment of the possibilities and the challenges of modern nanomedicine that will enable the development of clinically effective nanoparticulate drug delivery products and systems.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eNanoparticulate Drug Delivery Systems\u003c\/i\u003e focuses on the rationales and preclinical evaluation of new nanoparticulate drug carriers that have yet to be thoroughly reviewed in the literature. The first chapter sets the stage with a general overview of targeted nanomedicine. The book then explores new and promising nanoparticulate drug delivery systems, including:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eLipid nanoparticles for the delivery of nucleic acids\u003c\/li\u003e \u003cli\u003eMultifunctional dendritic nanocarriers\u003c\/li\u003e \u003cli\u003ePolymer drug nanoconjugates\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eNext, the book presents new opportunities and challenges for nanoparticulate drug delivery systems, including:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eClearance of nanoparticles during circulation\u003c\/li\u003e \u003cli\u003eDrug delivery strategies for combatting multiple drug resistance\u003c\/li\u003e \u003cli\u003eToxicological assessment of nanomedicine\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eChapters offer state-of-the-technology reviews with extensive references to facilitate further investigation. Moreover, each chapter concludes with an expert assessment of remaining challenges, pointing the way to solutions and new avenues of research.\u003c\/p\u003e \u003cp\u003eWith its frank discussions of opportunities and challenges, \u003ci\u003eNanoparticulate Drug Delivery Systems\u003c\/i\u003e sets a solid foundation for new research leading to the discovery and development of better nanomedicines.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989671330021,"sku":"NP9781118148877","price":179.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781118148877.jpg?v=1761785043","url":"https:\/\/k12savings.com\/products\/nanoparticulate-drug-delivery-systems-isbn-9781118148877","provider":"K12savings","version":"1.0","type":"link"}