{"product_id":"modern-size-exclusion-liquid-chromatography-isbn-9780471201724","title":"Modern Size-Exclusion Liquid Chromatography","description":"The \u003ci\u003eSecond Edition\u003c\/i\u003e of \u003ci\u003eModern Size-Exclusion Chromatography\u003c\/i\u003e offers a complete guide to the theories, methods, and applications of size-exclusion chromatography. It provides an unparalleled, integrated, up-to-date treatment of gel permeation and gel filtration chromatography. With its detailed descriptions of techniques, data handling, compilations of information on columns and column packings, and tables of important solvents and reference materials, the book offers readers everything they need to take full advantage of this popular macromolecular characterization technique.  \u003cp\u003eSince publication of the first edition in 1979, there have been many important advances in the field of size-exclusion chromatography. This Second Edition brings the book thoroughly up to date, with expert coverage of:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eNew and emerging industrial and research applications\u003c\/li\u003e \u003cli\u003ePractical aspects of size-exclusion chromatography (SEC) and multidetector and multidimensional SEC technologies for polymer architecture and copolymer analysis\u003c\/li\u003e \u003cli\u003eUpdated information on the latest equipment and techniques\u003c\/li\u003e \u003cli\u003eNew best practices for the lab\u003c\/li\u003e \u003cli\u003eSEC in relation to polymer characterization techniques such as GPEC, LCCC, and rheology\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThroughout the text, detailed examples guide you step by step through all the latest techniques and applications. With its extensive revisions and updates written by leading experts and pioneers in the field, Modern Size-Exclusion Liquid Chromatography remains the definitive resource for the broad range of researchers and scientists who use HPLC and GPC methods.\u003c\/p\u003e  Foreword.  \u003cp\u003ePreface.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Background.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 Introduction.\u003c\/p\u003e \u003cp\u003e1.2 History.\u003c\/p\u003e \u003cp\u003e1.3 Utility of SEC.\u003c\/p\u003e \u003cp\u003e1.4 Molar Mass Averages and Molar Mass Distribution.\u003c\/p\u003e \u003cp\u003e1.5 Structure of The Book.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Retention.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 Introduction.\u003c\/p\u003e \u003cp\u003e2.2 Solute Retention in LC.\u003c\/p\u003e \u003cp\u003e2.3 Solute Retention in SEC.\u003c\/p\u003e \u003cp\u003e2.4 SEC Retention Mechanism.\u003c\/p\u003e \u003cp\u003e2.5 Theoretical Models of SEC Separation.\u003c\/p\u003e \u003cp\u003e2.6 Other Considerations.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Band Broadening.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction.\u003c\/p\u003e \u003cp\u003e3.2 LC Plate Theory.\u003c\/p\u003e \u003cp\u003e3.3 Mechanism of SEC Band Broadening.\u003c\/p\u003e \u003cp\u003e3.4 Influencing Factors.\u003c\/p\u003e \u003cp\u003e3.5 Experimental Methods.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Resolution.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction.\u003c\/p\u003e \u003cp\u003e4.2 Resolution Concept in SEC of Polymers.\u003c\/p\u003e \u003cp\u003e4.3 Molar Mass Accuracy Criterion.\u003c\/p\u003e \u003cp\u003e4.4 Applications of Column Performance Criteria .\u003c\/p\u003e \u003cp\u003e4.5 Pore Geometry and Operational Effects.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Equipment.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Introduction.\u003c\/p\u003e \u003cp\u003e5.2 Extra-Column Effects: General.\u003c\/p\u003e \u003cp\u003e5.3 Mobile-Phase Reservoirs, Inlet Filters, and Degassers.\u003c\/p\u003e \u003cp\u003e5.4 Solvent-Metering Systems (Pumps).\u003c\/p\u003e \u003cp\u003e5.5 Sample Injectors and Autosamplers.\u003c\/p\u003e \u003cp\u003e5.6 Miscellaneous Hardware.\u003c\/p\u003e \u003cp\u003e5.7 Laboratory Safety.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 The Column.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction.\u003c\/p\u003e \u003cp\u003e6.2 Column Packings.\u003c\/p\u003e \u003cp\u003e6.3 Column-Packing Methods.\u003c\/p\u003e \u003cp\u003e6.4 Column Performance.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Experimental Variables and Techniques.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 Introduction.\u003c\/p\u003e \u003cp\u003e7.2 Solvent Effects.\u003c\/p\u003e \u003cp\u003e7.3 Substrate Effects.\u003c\/p\u003e \u003cp\u003e7.4 Sample Effects.\u003c\/p\u003e \u003cp\u003e7.5 Laboratory Techniques.\u003c\/p\u003e \u003cp\u003e7.6 Solvent Selection and Preparation.\u003c\/p\u003e \u003cp\u003e7.7 Selection and Use of Standard Reference Materials.\u003c\/p\u003e \u003cp\u003e7.8 Detector Selection.\u003c\/p\u003e \u003cp\u003e7.9 Column Selection and Handling.\u003c\/p\u003e \u003cp\u003e7.10 Chromatographic Design Considerations.\u003c\/p\u003e \u003cp\u003e7.11 Making the Separation.\u003c\/p\u003e \u003cp\u003e7.12 Troubleshooting.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Calibration\u003c\/b\u003e.\u003c\/p\u003e \u003cp\u003e8.1 Introduction.\u003c\/p\u003e \u003cp\u003e8.2 Calibration with Narrow-MMD Standards.\u003c\/p\u003e \u003cp\u003e8.3 Calibration with Broad-MMD Standards.\u003c\/p\u003e \u003cp\u003e8.4 Accuracy of Calibration Methods.\u003c\/p\u003e \u003cp\u003e8.5 Actual Molar Mass Across the SEC Elution Curve.\u003c\/p\u003e \u003cp\u003e8.6 Linear Calibration Ranges.\u003c\/p\u003e \u003cp\u003e8.7 Recent Developments and Recommendations on Band-Broadening Correction.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Physical Detectors.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9.1 Introduction.\u003c\/p\u003e \u003cp\u003e9.2 Concentration-Sensitive Detectors.\u003c\/p\u003e \u003cp\u003e9.3 Static Light-Scattering Detection.\u003c\/p\u003e \u003cp\u003e9.4 Quasielastic Light-Scattering Detection.\u003c\/p\u003e \u003cp\u003e9.5 Viscometric Detection.\u003c\/p\u003e \u003cp\u003e9.6 SEC3.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Chemical Detectors.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e10.1 Introduction.\u003c\/p\u003e \u003cp\u003e10.2 Mass Spectrometry.\u003c\/p\u003e \u003cp\u003e10.3 Fourier Transform Infrared Spectroscopy.\u003c\/p\u003e \u003cp\u003e10.4 Nuclear Magnetic Resonance Spectroscopy.\u003c\/p\u003e \u003cp\u003e10.5 Other Chemical Detectors.\u003c\/p\u003e \u003cp\u003e10.6 Coupling of Chemical Detectors.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Polymer Architecture and Dilute Solution Thermodynamics.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11.1 Introduction.\u003c\/p\u003e \u003cp\u003e11.2 Long-Chain Branching.\u003c\/p\u003e \u003cp\u003e11.3 Determining the Short-Chain Branching Distribution.\u003c\/p\u003e \u003cp\u003e11.4 Polymer Architecture: Conformation and Topology.\u003c\/p\u003e \u003cp\u003e11.5 Star Polymers.\u003c\/p\u003e \u003cp\u003e11.6 Determining the Persistence Length.\u003c\/p\u003e \u003cp\u003e11.7 Determining the Characteristic Ratio.\u003c\/p\u003e \u003cp\u003e11.8 Local Polydispersity.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Aqueous SEC.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e12.1 Introduction.\u003c\/p\u003e \u003cp\u003e12.2 Aqueous SEC Columns.\u003c\/p\u003e \u003cp\u003e12.3 Non-Size-Exclusion Effects and Mobile-Phase Additives.\u003c\/p\u003e \u003cp\u003e12.4 Select Applications of Aqueous SEC.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Oligomeric SEC.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e13.1 Introduction.\u003c\/p\u003e \u003cp\u003e13.2 What is an Oligomer?\u003c\/p\u003e \u003cp\u003e13.3 Preliminary Considerations.\u003c\/p\u003e \u003cp\u003e13.4 Oligomeric SEC Columns.\u003c\/p\u003e \u003cp\u003e13.5 Select Applications of Oligomeric SEC.\u003c\/p\u003e \u003cp\u003e13.6 Optimizing Resolution in Oligomeric SEC.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 SEC in 2D-LC Separations.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e14.1 Introduction.\u003c\/p\u003e \u003cp\u003e14.2 Principles of 2D Polymer Separations.\u003c\/p\u003e \u003cp\u003e14.3 Designing an Experimental 2D-LC Protocol.\u003c\/p\u003e \u003cp\u003e14.4 Eluent Transfer in 2D-LC.\u003c\/p\u003e \u003cp\u003e14.5 Stop-Flow SEC × LC.\u003c\/p\u003e \u003cp\u003e14.6 Select Applications of 2D-LC.\u003c\/p\u003e \u003cp\u003e14.7 SEC in 3D Separations.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Special Techniques.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e15.1 Introduction.\u003c\/p\u003e \u003cp\u003e15.2 Preparative SEC.\u003c\/p\u003e \u003cp\u003e15.3 Recycle SEC.\u003c\/p\u003e \u003cp\u003e15.4 High-Speed SEC.\u003c\/p\u003e \u003cp\u003e15.5 Inverse SEC.\u003c\/p\u003e \u003cp\u003e15.6 Vacancy and Differential SEC.\u003c\/p\u003e \u003cp\u003e15.7 Size-Exclusion Electrochromatography.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 High-Temperature SEC and Rheological Connections.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e16.1 Introduction.\u003c\/p\u003e \u003cp\u003e16.2 High-Temperature SEC.\u003c\/p\u003e \u003cp\u003e16.3 Complementarity of SEC and Rheology.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003eSymbols.\u003c\/p\u003e \u003cp\u003eAbbreviations.\u003c\/p\u003e \u003cp\u003eIndex.\u003c\/p\u003e \"The authors have balanced well-written text with diagrams, figures, and equations to provide a user-friendly guide to practical modern SEC. The inclusion of both classical and current references with each chapter demonstrates the utility of each chapter and discussion. This text would be useful for scientists at any level, whether using SEC for the first time or the 1,000th.\" (Anal Bioanal Chem, 2011)  \u003cp\u003e \"With its extensive revisions and updates written by leading experts and pioneers in the field, Modern Size-Exclusion Liquid Chromatography offers readers everything they need to take full advantage of this popular macromolecular characterisation technique.\" (Chemistry Journals, 11 April 2011)\u003c\/p\u003e  \u003cp\u003eAndré M. Striegel, PhD, is Assistant Professor in the Department of Chemistry \u0026amp; Biochemistry at the Florida State University, with previous industrial R\u0026amp;D experience at Solutia. He has published and lectured extensively in the area of polymer chromatography and is the recipient of several national awards in analytical chemistry. WALLACE W. YAU, PhD, received his doctorate in physical chemistry from University of Massachusetts and is currently a scientist specialist at Dow Chemical Co., with past industrial experience at DuPont and Chevron. He has been in GPC research and polymer characterization for the past four decades. JOSEPH J. KIRKLAND, PhD, is author or coauthor of eight widely read books on liquid chromatography, more than 150 peer-reviewed papers, and thirty patents. With over fifty years of industrial experience, he has been the recipient of many major national and international awards in analytical chemistry. DONALD D. BLY, PhD, retired as manager of analytical science, central research, DuPont. He has remained working as a consultant to analytical and analytical-polymer science businesses and has remained active in the American Chemical Society and ASTM.\u003c\/p\u003e  \u003cp\u003eCovers all aspects of size-exclusion chromatography, including the latest findings and applications\u003c\/p\u003e \u003cp\u003eThe Second Edition of Modern Size-Exclusion Liquid Chromatography is your complete guide to the theories, methods, and applications of size-exclusion chromatography. It provides an unparalleled, integrated, up-to-date treatment of gel permeation and gel filtration chromatography. With its detailed descriptions of techniques, data handling, compilations of information on columns and column packings, and tables of important solvents and reference materials, the book offers readers everything they need to take full advantage of this popular macromolecular characterization technique.\u003c\/p\u003e \u003cp\u003eSince publication of the first edition in 1979, there have been many important advances in the field of size-exclusion chromatography. This Second Edition brings the book thoroughly up to date, with expert coverage of:\u003c\/p\u003e \u003cul\u003e \u003cli\u003e \u003cp\u003eNew and emerging industrial and research applications\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003ePractical aspects of size-exclusion chromatography (SEC) and multidetector and multidimensional SEC technologies for polymer architecture and copolymer analysis\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eUpdated information on the latest equipment and techniques\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eNew best practices for the lab\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eSEC in relation to polymer characterization techniques such as GPEC, LCCC, and rheology\u003c\/p\u003e \u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThroughout the text, detailed examples guide you step by step through all the latest techniques and applications. With its extensive revisions and updates written by leading experts and pioneers in the field, Modern Size-Exclusion Liquid Chromatography remains the definitive resource for the broad range of researchers and scientists who use HPLC and GPC methods.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989644460261,"sku":"NP9780471201724","price":193.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780471201724.jpg?v=1761784937","url":"https:\/\/k12savings.com\/products\/modern-size-exclusion-liquid-chromatography-isbn-9780471201724","provider":"K12savings","version":"1.0","type":"link"}