{"product_id":"microbiology-isbn-9781119592495","title":"Microbiology","description":"\u003cp\u003e\u003cb\u003eIdeal for microbiology\/science majors\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eThe third edition of \u003ci\u003eMicrobiology\u003c\/i\u003e provides in-depth coverage of the science of microscopic organisms. Providing a balanced presentation of foundational concepts, real-world applications, and current research and experimentation, this comprehensive textbook facilitates a thorough understanding of the scope, nature, and complexity of microbiology. The text approaches the subject within the context of exploration and experimentation, integrating a wealth of classroom-tested pedagogical features. The material is organized around the three pillars of physiology, ecology and genetics — helping students appreciate the interconnected and dynamic nature of microbiology as they explore individual microbes and the relation between different types of microbes, other organisms, and the environment.\u003c\/p\u003e \u003cp\u003eDetailed yet accessible chapters illustrate how an experiment proceeds, explain how microbes replicate, clarify the flow of concept processes, and summarize key points. Challenging end-of-chapter questions both test students' understanding of the material and strengthen critical thinking skills. This new edition contains up-to-date coverage of topics including DNA replication and gene expression, viral pathogenesis, microbial biotechnology, adaptive immunity, the control of infectious diseases, the microbiology of food and water, and integrated coverage of COVID-19.\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I \u003c\/b\u003e\u003cb\u003eThe Microbes\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 \u003c\/b\u003e\u003cb\u003eThe Microbial World 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 The Microbes 3\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research the Three Domains of Life 9\u003c\/p\u003e \u003cp\u003eToolbox 1.1 Polymerase Chain Reaction Amplification of rRNA Genes 11\u003c\/p\u003e \u003cp\u003e1.2 Microbial Physiology, Genetics, and Cultivation 14\u003c\/p\u003e \u003cp\u003ePerspective 1.1 Creating Life in the Laboratory: The Miller–Urey Experiment 17\u003c\/p\u003e \u003cp\u003e1.3 Microbial Ecology and Biotechnology 23\u003c\/p\u003e \u003cp\u003e1.4 Microbes and Disease 25\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 \u003c\/b\u003e\u003cb\u003eBacteria 35\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 Morphology of Bacterial Cells 36\u003c\/p\u003e \u003cp\u003ePerspective 2.1 Making the Microbiology Laboratory Accessible 39\u003c\/p\u003e \u003cp\u003e2.2 The Cytoplasm 40\u003c\/p\u003e \u003cp\u003e2.3 The Bacterial Cytoskeleton 43\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research Magnetosomes: Uncovering the Structure of Bacterial Organelles 44\u003c\/p\u003e \u003cp\u003e2.4 The Cell Envelope 46\u003c\/p\u003e \u003cp\u003eToolbox 2.1 The Gram Stain 55\u003c\/p\u003e \u003cp\u003ePerspective 2.2 The Protective Shells of Endospores 56\u003c\/p\u003e \u003cp\u003e2.5 The Bacterial Cell Surface 60\u003c\/p\u003e \u003cp\u003e2.6 Diversity of Bacteria 67\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 \u003c\/b\u003e\u003cb\u003eEukaryal Microorganisms 75\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Morphology of Eukaryal Cells 76\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research Lipid Rafts: Organized Clustering of Lipids within a Membrane 82\u003c\/p\u003e \u003cp\u003eToolbox 3.1 Using Microscopy to Examine Cell Structure 85\u003c\/p\u003e \u003cp\u003ePerspective 3.1 Hijacking the Cytoskeleton 88\u003c\/p\u003e \u003cp\u003e3.2 Diversity of Eukaryal Microorganisms 89\u003c\/p\u003e \u003cp\u003e3.3 Replication of Eukaryal Microorganisms 94\u003c\/p\u003e \u003cp\u003e3.4 The Origin of Eukaryal Cells 97\u003c\/p\u003e \u003cp\u003ePerspective 3.2 Secondary endosymbiosis: The origins of an organelle with four membranes 101\u003c\/p\u003e \u003cp\u003e3.5 Interactions Between Eukaryal Microorganisms and Animals, Plants, and the Environment 102\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 \u003c\/b\u003e\u003cb\u003eArchaea 109\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Evolution of Archaea 111\u003c\/p\u003e \u003cp\u003e4.2 Archaeal Cell Structure 113\u003c\/p\u003e \u003cp\u003eToolbox 4.1 Vaccine Delivery Strategies 117\u003c\/p\u003e \u003cp\u003e4.3 Diversity of Archaea 121\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research The Role of Archaea in Our Digestive System 124\u003c\/p\u003e \u003cp\u003ePerspective 4.1 Extremophiles and Biotechnology 129\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 \u003c\/b\u003e\u003cb\u003eViruses 136\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 A Basic Overview of Viruses 137\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research New Findings in the Packaging of DNA by the Model Bacteriophage T4 146\u003c\/p\u003e \u003cp\u003e5.2 Origins of Viruses 148\u003c\/p\u003e \u003cp\u003ePerspective 5.1 Ribozymes: Evidence for an RNA-Based World 149\u003c\/p\u003e \u003cp\u003e5.3 Cultivation, Purification, and Quantification of Viruses 150\u003c\/p\u003e \u003cp\u003eToolbox 5.1 Cell Culture Techniques 151\u003c\/p\u003e \u003cp\u003ePerspective 5.2 Measurement of HIV Viral Load 155\u003c\/p\u003e \u003cp\u003e5.4 Diversity of Viruses 158\u003c\/p\u003e \u003cp\u003eToolbox 5.2 Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) 162\u003c\/p\u003e \u003cp\u003e5.5 Virus-Like Particles 163\u003c\/p\u003e \u003cp\u003e5.6 Virology Today 166\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 \u003c\/b\u003e\u003cb\u003eMetabolism 172\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 Acquisition of Carbon, Energy, and Electrons 174\u003c\/p\u003e \u003cp\u003e6.2 Energy, Enzymes, and ATP 176\u003c\/p\u003e \u003cp\u003ePerspective 6.1 Who Needs Vitamins? 179\u003c\/p\u003e \u003cp\u003e6.3 Central Processes in ATP Synthesis 180\u003c\/p\u003e \u003cp\u003e6.4 Carbon Utilization in Microorganisms 185\u003c\/p\u003e \u003cp\u003e6.5 Respiration and the Electron Transport System 195\u003c\/p\u003e \u003cp\u003ePerspective 6.2 Electricigenic Bacteria and Microbial Fuel Cells 198\u003c\/p\u003e \u003cp\u003e6.6 Metabolism of Non-glucose Carbon Sources 202\u003c\/p\u003e \u003cp\u003eToolbox 6.1 Metabolism and Rapid Bacterial Identification Systems 204\u003c\/p\u003e \u003cp\u003e6.7 Phototrophy and Photosynthesis 206\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research Genome Sequence of a Deep Sea Symbiont 216\u003c\/p\u003e \u003cp\u003e6.8 Nitrogen and Sulfur Metabolism 217\u003c\/p\u003e \u003cp\u003e6.9 Biosynthesis of Cellular Components 222\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart II Microbial Genetics\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 \u003c\/b\u003eCultivating Microorganisms \u003cb\u003e231\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 Factors Affecting Microbial Growth 233\u003c\/p\u003e \u003cp\u003eToolbox 7.1 Phenotype Microarrays for Examining Microbial Growth 234\u003c\/p\u003e \u003cp\u003e7.2 Growing Microorganisms in the Laboratory 238\u003c\/p\u003e \u003cp\u003ePerspective 7.1 The Discovery of \u003ci\u003eHelicobacter pylori \u003c\/i\u003e243\u003c\/p\u003e \u003cp\u003eToolbox 7.2 FISHING for Uncultivated Microorganisms 246\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research Bringing to Life the Previously Unculturable Using the Soil Substrate Membrane System (SSMS) 247\u003c\/p\u003e \u003cp\u003e7.3 Measuring Microbial Population Growth 249\u003c\/p\u003e \u003cp\u003ePerspective 7.2 \u003ci\u003eMycobacterium leprae\u003c\/i\u003e, An Extraordinarily Slow-growing Pathogen 255\u003c\/p\u003e \u003cp\u003ePerspective 7.3 The Human Intestine: A Continuous Culture 257\u003c\/p\u003e \u003cp\u003e7.4 Eliminating Microbes and Preventing their Growth 257\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 DNA Replication and Gene Expression 267\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8.1 The Role of DNA 269\u003c\/p\u003e \u003cp\u003e8.2 DNA Replication 276\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research Telomeres with Promoter Activity 283\u003c\/p\u003e \u003cp\u003e8.3 Transcription 284\u003c\/p\u003e \u003cp\u003eToolbox 8.1 Using a Gel Shift Assay to Identify DNA-binding Proteins 287\u003c\/p\u003e \u003cp\u003e8.4 Translation 291\u003c\/p\u003e \u003cp\u003e8.5 The Effects of Mutations 297\u003c\/p\u003e \u003cp\u003ePerspective 8.1 Using Mutations to Control Viral Infections 301\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Viral Replication Strategies 306\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9.1 Recognition of Host Cells 308\u003c\/p\u003e \u003cp\u003ePerspective 9.1 Identifying Emerging Viral Pathogens 310\u003c\/p\u003e \u003cp\u003eToolbox 9.1 The Western Blot 312\u003c\/p\u003e \u003cp\u003e9.2 Viral Entry and Uncoating 315\u003c\/p\u003e \u003cp\u003e9.3 Viral Replication 319\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research The Discovery of Reverse Transcriptase 326\u003c\/p\u003e \u003cp\u003ePerspective 9.2 Phage Therapy: Biocontrol for Infections 328\u003c\/p\u003e \u003cp\u003e9.4 Viral Assembly and Egress 330\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Bacterial Genetic Analysis and Manipulation 335\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e10.1 Bacteria as Subjects of Genetic Research 336\u003c\/p\u003e \u003cp\u003e10.2 Mutations, Mutants, and Strains 340\u003c\/p\u003e \u003cp\u003eToolbox 10.1 Isolating Nutritional Mutants 342\u003c\/p\u003e \u003cp\u003e10.3 Restriction Enzymes, Vectors, and Cloning 347\u003c\/p\u003e \u003cp\u003e10.4 Recombination and DNA Transfer 354\u003c\/p\u003e \u003cp\u003ePerspective 10.1 Plasmids That Produce Pathogens 359\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research The Discovery of Transduction 367\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Microbial Genomics 372\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11.1 Genome Sequencing 373\u003c\/p\u003e \u003cp\u003ePerspective 11.1 Rate of DNA Sequencing 377\u003c\/p\u003e \u003cp\u003eToolbox 11.1 Genome databases 383\u003c\/p\u003e \u003cp\u003e11.2 Genomic Analysis of Gene Expression 385\u003c\/p\u003e \u003cp\u003e11.3 Comparative Genomics 391\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research Genome Sequence of a Killer Bug 391\u003c\/p\u003e \u003cp\u003ePerspective 11.2 The Minimal Genome 393\u003c\/p\u003e \u003cp\u003e11.4 Metagenomics and Related Analyses 396\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Regulation of Gene Expression 402\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e12.1 Differential Gene Expression 404\u003c\/p\u003e \u003cp\u003e12.2 The Operon 405\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research Tuning Promoters for Use in Synthetic Biology 412\u003c\/p\u003e \u003cp\u003e12.3 Global Gene Regulation 413\u003c\/p\u003e \u003cp\u003ePerspective 12.1 The Use of Lactose Analogs in Gene Expression Studies 415\u003c\/p\u003e \u003cp\u003e12.4 Post-Initiation Control of Gene Expression 419\u003c\/p\u003e \u003cp\u003eToolbox 12.1 Using RNA molecules to decrease gene expression 421\u003c\/p\u003e \u003cp\u003e12.5 Quorum Sensing 423\u003c\/p\u003e \u003cp\u003e12.6 Two-Component Regulatory Systems 425\u003c\/p\u003e \u003cp\u003e12.7 Chemotaxis 428\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Biogeochemical Cycles 435\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e13.1 Nutrient Cycling 437\u003c\/p\u003e \u003cp\u003eToolbox 13.1 Using Microarrays to Examine Microbial Communities: The GeoChip 439\u003c\/p\u003e \u003cp\u003e13.2 Cycling Driven by Carbon Metabolism 440\u003c\/p\u003e \u003cp\u003ePerspective 13.1 CO2 as a Greenhouse Gas and Its Influence on Climate Change 440\u003c\/p\u003e \u003cp\u003e13.3 Cycling Driven by Nitrogen Metabolism 451\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research The First Isolation and Cultivation of a Marine Archaeon 454\u003c\/p\u003e \u003cp\u003e13.4 Other Cycles and their Connections 456\u003c\/p\u003e \u003cp\u003ePerspective 13.2 Life in a World without Microbes 457\u003c\/p\u003e \u003cp\u003ePerspective 13.3 The Microbiology of Environmentally Toxic Acid Mine Drainage 458\u003c\/p\u003e \u003cp\u003eToolbox 13.2 Biogeochemistry in a Bottle: The Winogradsky Column 461\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart III Microbial Physiology and Ecology\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 \u003c\/b\u003eMicrobial Ecosystems \u003cb\u003e465\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e14.1 Microbes in the Environment 467\u003c\/p\u003e \u003cp\u003e14.2 Microbial Community Analysis 472\u003c\/p\u003e \u003cp\u003eToolbox 14.1 Flow Cytometry 477\u003c\/p\u003e \u003cp\u003ePerspective 14.1 Naming the Uncultured and Uncharacterized 479\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research Insights into the Phylogeny and Coding Potential of Microbial Dark Matter 479\u003c\/p\u003e \u003cp\u003e14.3 Aquatic Ecosystems 481\u003c\/p\u003e \u003cp\u003ePerspective 14.2 Dead Zones 482\u003c\/p\u003e \u003cp\u003e14.4 Terrestrial Ecosystems 489\u003c\/p\u003e \u003cp\u003e14.5 Deep Subsurface and Geothermal Ecosystems 495\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Microbial Symbionts 504\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e15.1 Types of Microbe-Host Interactions 506\u003c\/p\u003e \u003cp\u003e15.2 Symbionts of Plants 508\u003c\/p\u003e \u003cp\u003ePerspective 15.1 The Possible Impossible Vegan Patty 510\u003c\/p\u003e \u003cp\u003e15.3 Symbionts of Humans 513\u003c\/p\u003e \u003cp\u003eToolbox 15.1 Germ-free and Gnotobiotic Animals 518\u003c\/p\u003e \u003cp\u003ePerspective 15.2 Food Probiotics—Do They Work? 519\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research Fecal Bacteriotherapy: “Repoopulation” of the Gut 522\u003c\/p\u003e \u003cp\u003e15.4 Symbionts of Herbivores 525\u003c\/p\u003e \u003cp\u003ePerspective 15.3 Cows Contribute to Climate Change 531\u003c\/p\u003e \u003cp\u003e15.5 Symbionts of Invertebrates 531\u003c\/p\u003e \u003cp\u003ePerspective 15.4 Midichlorians—Not Just for Jedi 536\u003c\/p\u003e \u003cp\u003ePerspective 15.5 Death of Coral Reefs 539\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 Microbial Biotechnology 544\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e16.1 Microbes for Biotechnology 546\u003c\/p\u003e \u003cp\u003ePerspective 16.1 Bioprospecting: Who Owns the Microbes? 548\u003c\/p\u003e \u003cp\u003e16.2 Molecular Genetic Modification 550\u003c\/p\u003e \u003cp\u003eToolbox 16.1 Site-Directed Mutagenesis 552\u003c\/p\u003e \u003cp\u003eToolbox 16.2 Fusion Protein Purification 559\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research Making a Synthetic Genome 561\u003c\/p\u003e \u003cp\u003ePerspective 16.2 The International Genetically Engineered Machine (iGEM) Competition, Standard Biological Parts, and Synthetic Biology 564\u003c\/p\u003e \u003cp\u003e16.3 Red Biotechnology 565\u003c\/p\u003e \u003cp\u003e16.4 White Biotechnology 566\u003c\/p\u003e \u003cp\u003ePerspective 16.3 Biofuels: Biodiesel and Algae 570\u003c\/p\u003e \u003cp\u003e16.5 Green Biotechnology 576\u003c\/p\u003e \u003cp\u003eToolbox 16.3 Plant Transformation Using Bacteria 578\u003c\/p\u003e \u003cp\u003e\u003cb\u003e17 The Microbiology of Food and Water 586\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e17.1 Food Spoilage 588\u003c\/p\u003e \u003cp\u003e17.2 Food Preservation 591\u003c\/p\u003e \u003cp\u003e17.3 Food Fermentation 598\u003c\/p\u003e \u003cp\u003e17.4 Foodborne and Waterborne Illness 605\u003c\/p\u003e \u003cp\u003e17.5 Microbiological Aspects of Water Quality 607\u003c\/p\u003e \u003cp\u003ePerspective 17.1 Implications of Sludge Bulking 613\u003c\/p\u003e \u003cp\u003eToolbox 17.1 Measuring Biochemical Oxygen Demand (BOD) 614\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research Enhanced Biological Removal of Phosphorus 616\u003c\/p\u003e \u003cp\u003eToolbox 17.2 Most Probable Number (MPN) Method 619\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart IV Microbes and Disease\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e18 Introduction to Infectious Diseases 624\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e18.1 Pathogenic Microbes 627\u003c\/p\u003e \u003cp\u003eToolbox 18.1 Measuring the Virulence of Pathogens 629\u003c\/p\u003e \u003cp\u003e18.2 Microbial Virulence Strategies 631\u003c\/p\u003e \u003cp\u003ePerspective 18.1 Genome Editing: A powerful and Controversial New Technique 637\u003c\/p\u003e \u003cp\u003e18.3 The Transmission of Infectious Diseases 638\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research Epidemiology of an Infectious Disease 645\u003c\/p\u003e \u003cp\u003e18.4 Proving Cause and Effect in Microbial Infections 648\u003c\/p\u003e \u003cp\u003ePerspective 18.2 The Armadillo—An Ideal Animal Model? 651\u003c\/p\u003e \u003cp\u003e18.5 The Evolution of Pathogens 652\u003c\/p\u003e \u003cp\u003e\u003cb\u003e19 Innate Host Defenses Against Microbial Invasion 661\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e19.1 Immunity 682\u003c\/p\u003e \u003cp\u003e19.2 Barriers to Infection 664\u003c\/p\u003e \u003cp\u003ePerspective 19.1 Messy Mucus 666\u003c\/p\u003e \u003cp\u003ePerspective 19.2 Alzheimer’s Disease: Aluminium, B-amyloid, Gum Disease: Which Is It? 666\u003c\/p\u003e \u003cp\u003e19.3 The Inflammatory Response 669\u003c\/p\u003e \u003cp\u003e19.4 The Molecules of the Innate System 671\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research Mammalian Cells Can Recognize Bacterial DNA 673\u003c\/p\u003e \u003cp\u003eToolbox 19.1 The Complement Fixation Test 677\u003c\/p\u003e \u003cp\u003e19.5 The Cells of Innate Immunity 682\u003c\/p\u003e \u003cp\u003e19.6 Invertebrate Defenses 690\u003c\/p\u003e \u003cp\u003eToolbox 19.2 The \u003ci\u003eLimulus \u003c\/i\u003eAmoebocyte Assay for LPS 692\u003c\/p\u003e \u003cp\u003e\u003cb\u003e20 Adaptive Immunity 696\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e20.1 Features of Adaptive Immunity 698\u003c\/p\u003e \u003cp\u003e20.2 T Cells 701\u003c\/p\u003e \u003cp\u003e20.3 Antigen Processing 705\u003c\/p\u003e \u003cp\u003e20.4 Antigen-Presenting Cells 708\u003c\/p\u003e \u003cp\u003e20.5 Humoral and Cell-Mediated Immune Responses 712\u003c\/p\u003e \u003cp\u003ePerspective 20.1 Too Much of a Good Thing? 714\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research Attempting to Engineer a Virus to Improve Immunocontraception 715\u003c\/p\u003e \u003cp\u003e20.6 B Cells and the Production of Antibody 716\u003c\/p\u003e \u003cp\u003ePerspective 20.2 Vaccines Against T-independent Antigens 720\u003c\/p\u003e \u003cp\u003eToolbox 20.1 Monoclonal Antibody (mAb) Production 721\u003c\/p\u003e \u003cp\u003eToolbox 20.2 Enzyme-linked Immunosorbent Assay (ELISA) 727\u003c\/p\u003e \u003cp\u003ePerspective 20.3 Turning Antibody Upside Down 729\u003c\/p\u003e \u003cp\u003e\u003cb\u003e21 Bacterial Pathogenesis 735\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e21.1 Bacterial Virulence Factors 737\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research \u003ci\u003eEscherichia Coli \u003c\/i\u003eInjects Its Own Receptor 742\u003c\/p\u003e \u003cp\u003ePerspective 21.1 Iron, Vampires, Fashion, and the White Plague 747\u003c\/p\u003e \u003cp\u003e21.2 Bacterial Virulence Factors—Toxins 748\u003c\/p\u003e \u003cp\u003eToolbox 21.1 Serotyping 749\u003c\/p\u003e \u003cp\u003ePerspective 21.2 The Good, The Bad, and The Ugly Side of Botulinum Toxin 756\u003c\/p\u003e \u003cp\u003ePerspective 21.3 Superabsorbent Tampons and Superantigens 762\u003c\/p\u003e \u003cp\u003e21.3 Survival in the Host: Strategies and Consequences 764\u003c\/p\u003e \u003cp\u003eToolbox 21.2 The Tuberculin Test for Tuberculosis 772\u003c\/p\u003e \u003cp\u003e21.4 Evolution of Bacterial Pathogens 772\u003c\/p\u003e \u003cp\u003ePerspective 21.4 Antibiotics Trigger Toxins? 776\u003c\/p\u003e \u003cp\u003e\u003cb\u003e22 Viral Pathogenesis 782\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e22.1 Recurring Themes in Viral Pathogenesis 784\u003c\/p\u003e \u003cp\u003ePerspective 22.1 Vertical Transmission of HIV 789\u003c\/p\u003e \u003cp\u003e22.2 Interactions with the Host: Strategies and Consequences 791\u003c\/p\u003e \u003cp\u003ePerspective 22.2 Viral Induction of Apoptosis 793\u003c\/p\u003e \u003cp\u003e22.3 Viral Infections and Cancer 796\u003c\/p\u003e \u003cp\u003eToolbox 22.1 Immunoprecipitation 799\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research Viruses that Cause Cancer by Affecting Cellular Proliferation 800\u003c\/p\u003e \u003cp\u003ePerspective 22.3 SV40 and Human Cancers 802\u003c\/p\u003e \u003cp\u003e22.4 Evolution of Viral Pathogens 806\u003c\/p\u003e \u003cp\u003ePerspective 22.4 What is it about Bats? 809\u003c\/p\u003e \u003cp\u003ePerspective 22.5 Ethical Concerns about Avian Flu Research 812\u003c\/p\u003e \u003cp\u003e\u003cb\u003e23 Eukaryal Pathogenesis 816\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e23.1 Mechanisms of Eukaryal Pathogenesis 818\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research An Experimental System for the Genomic Study of Dutch Elm Disease 821\u003c\/p\u003e \u003cp\u003ePerspective 23.1 \u003ci\u003ePneumocystis Jirovecii \u003c\/i\u003eor \u003ci\u003eCarinii \u003c\/i\u003e: The Evolving Field of Taxonomy 824\u003c\/p\u003e \u003cp\u003ePerspective 23.2 Magic Mushrooms 830\u003c\/p\u003e \u003cp\u003e23.2 Pathogen Study: \u003ci\u003ePlasmodium Falciparum \u003c\/i\u003e831\u003c\/p\u003e \u003cp\u003eToolbox 23.1 Testing for Malaria 835\u003c\/p\u003e \u003cp\u003e23.3 Macroscopic Eukaryal Pathogens 837\u003c\/p\u003e \u003cp\u003e23.4 Evolution of Eukaryal Pathogens 839\u003c\/p\u003e \u003cp\u003ePerspective 23.3 Chytrid Fungus: An Emerging Fungal Pathogen 840\u003c\/p\u003e \u003cp\u003ePerspective 23.4 What if the Parasites Disappeared? 842\u003c\/p\u003e \u003cp\u003e\u003cb\u003e24 Control of Infectious Diseases 846\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e24.1 Historical Aspects of Infectious Disease Treatment and Control 848\u003c\/p\u003e \u003cp\u003e24.2 Antimicrobial Drugs 849\u003c\/p\u003e \u003cp\u003e24.3 Antimicrobial Drug Resistance 863\u003c\/p\u003e \u003cp\u003eMini-Paper: A Focus on the Research Tracking Acquisition of Antibiotic Resistance In Real Time 865\u003c\/p\u003e \u003cp\u003eToolbox 24.1 Drug Susceptibility Testing and MIC 869\u003c\/p\u003e \u003cp\u003ePerspective 24.1 The Pursuit of New Antibiotics: Why Bother? 874\u003c\/p\u003e \u003cp\u003ePerspective 24.2 Health Care-Associated Infections: A Recipe for Resistance 875\u003c\/p\u003e \u003cp\u003e24.4 Predicting and Controlling Epidemics 876\u003c\/p\u003e \u003cp\u003e24.5 Immunization and Vaccines 879\u003c\/p\u003e \u003cp\u003ePerspective 24.3 Variolation: Deliberate Infection with Smallpox Virus 880\u003c\/p\u003e \u003cp\u003ePerspective 24.4 The War Against Vaccines 885\u003c\/p\u003e \u003cp\u003eAppendix A Scientific Articles A-1\u003c\/p\u003e \u003cp\u003eAppendix B Microscopy A-10\u003c\/p\u003e \u003cp\u003eAppendix C Taxonomy and Nomenclature of Microbes A-14\u003c\/p\u003e \u003cp\u003eAppendix D Origin of Blood Cells A-16\u003c\/p\u003e \u003cp\u003eGlossary \/ Index\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989619654885,"sku":"NP9781119592495","price":111.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781119592495.jpg?v=1761784836","url":"https:\/\/k12savings.com\/products\/microbiology-isbn-9781119592495","provider":"K12savings","version":"1.0","type":"link"}