{"product_id":"introduction-to-proteomics-isbn-9780471754022","title":"Introduction to Proteomics","description":"\u003ci\u003eProteomics\u003c\/i\u003e provides an introductory insight on proteomics, discussing the basic principles of the field, how to apply specific technologies and instrumentation, and example applications in human health and diseases. With helpful study questions, this textbook presents an easy to grasp and solid overview and understanding of the principles, guidelines, and especially the complex instrumentation operations in proteomics for new students and research scientists. Written by a leader in proteomics studies, \u003ci\u003eProteomics\u003c\/i\u003e offers an expert perspective on the field and the future of proteomics.  \u003cb\u003eFOREWORD.\u003c\/b\u003e  \u003cp\u003e\u003cb\u003ePREFACE.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eABOUT THE AUTHOR.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 1 HISTORICAL PERSPECTIVES.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1. Introduction to Proteomics.\u003c\/p\u003e \u003cp\u003e1.2. Proteome and Proteomics.\u003c\/p\u003e \u003cp\u003e1.3. Genetics of Proteins.\u003c\/p\u003e \u003cp\u003e1.4. Molecular Biology of Genes and Proteins.\u003c\/p\u003e \u003cp\u003e1.5. Protein Chemistry Before Proteomics.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003eFurther Reading.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 2 PROTEOMICS—RELATION TO GENOMICS, BIOINFORMATICS.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1. Genomics.\u003c\/p\u003e \u003cp\u003e2.2. Bioinformatics and Computational Biology.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003eFurther Reading.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 3 METHODOLOGY FOR SEPARATION AND IDENTIFICATION OF PROTEINS AND THEIR INTERACTIONS.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1. Separation of Proteins Via a Multidimensional Approach.\u003c\/p\u003e \u003cp\u003e3.2. Determination of the Primary Structure of Proteins.\u003c\/p\u003e \u003cp\u003e3.3. Determination of the 3D Structure of a Protein.\u003c\/p\u003e \u003cp\u003e3.4. Determination of the Amount of Proteins.\u003c\/p\u003e \u003cp\u003e3.5. Structural and Functional Proteomics.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003eFurther Reading.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 4 PROTEOMICS OF PROTEIN MODIFICATIONS.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1. Phosphorylation and Phosphoproteomics.\u003c\/p\u003e \u003cp\u003e4.2. Glycosylation and Glycoproteomics.\u003c\/p\u003e \u003cp\u003e4.3. Ubiquitination and Ubiquitinomics.\u003c\/p\u003e \u003cp\u003e4.4. Miscellaneous Modifications of Proteins.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003eFurther Reading.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 5 PROTEOMICS OF PROTEIN–PROTEIN INTERACTIONS\/INTERACTOMES.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1. Protein—Protein Interactions (PPI) in Vivo.\u003c\/p\u003e \u003cp\u003e5.2. Analysis of Protein Interactions in Vitro.\u003c\/p\u003e \u003cp\u003e5.3. Analysis of Protein Interactions in Silico.\u003c\/p\u003e \u003cp\u003e5.4. Synthetic Genetic Methods to Determine Protein Interactions.\u003c\/p\u003e \u003cp\u003e5.5. Interactomes.\u003c\/p\u003e \u003cp\u003e5.6. Evolution and Conservation of Interactomes.\u003c\/p\u003e \u003cp\u003e5.7. Interactomes and the Complexity of Organisms: It is the Number of Interactomes that Matters in Understanding the Complexity of an Organism and not the Number of Genes.\u003c\/p\u003e \u003cp\u003e5.8. Interaction of Proteins with Small Molecules.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003eFurther Reading.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 6 APPLICATIONS OF PROTEOMICS I: PROTEOMICS, HUMAN DISEASE, AND MEDICINE.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1. Diseasome.\u003c\/p\u003e \u003cp\u003e6.2. Medical Proteomics.\u003c\/p\u003e \u003cp\u003e6.3. Clinical Proteomics.\u003c\/p\u003e \u003cp\u003e6.4. Metaproteomics and Human Health.\u003c\/p\u003e \u003cp\u003e6.5. Proteomics in Biotechnology and Industry of Drug Production.\u003c\/p\u003e \u003cp\u003e6.6. Metaproteomics of Microbial Fermentation.\u003c\/p\u003e \u003cp\u003e6.7. Beef Industry.\u003c\/p\u003e \u003cp\u003e6.8. Bioterrorism and Biodefense.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003eFurther Reading.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 7 PROTEOMICS—FUTURE DEVELOPMENTS.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1. Technical Scope of Proteomics—Beyond Protein Identification.\u003c\/p\u003e \u003cp\u003e7.2. Scientific Scope of Proteomics—Control of Epigenesis.\u003c\/p\u003e \u003cp\u003e7.3. Medical Scope of Proteomics.\u003c\/p\u003e \u003cp\u003e7.4. Proteomics, Energy Production, and Bioremediation.\u003c\/p\u003e \u003cp\u003e7.5. Proteomics and Biodefense.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003eFurther Reading.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eINDEX.\u003c\/b\u003e\u003c\/p\u003e \"The Author offers an expert perspective on the entire field, including: Easily accessible overview of the principles of proteomics; Coverage of real-world, cutting-edge medical applications, including personalized medicine; Clear guidelines on how to operate the complex instrumentation involved in proteomics; Discussion of the future of proteomics\". (Anticancer Research, 1 August 2010)  \u003cp\u003e This book provides a highly authoritative introduction to the promising and fast-advancing field of proteomics, examining the role proteomics plays in the study of biological systems in general and disease in particular. It helps readers understand the structure, function, and interactions of proteins and how this knowledge is used for identifying diseases and developing new drugs.\" (Forbes.com, 1 November 2010)\u003c\/p\u003e  \u003cp\u003e \"For undergraduate and graduate biology and non-biology students and new researchers, Mishra (molecular genetics and genomics, U. of South Carolina) introduces the field of proteomics and its role in the study of biological systems and disease.\" (\u003ci\u003eBook News\u003c\/i\u003e, September 2010)\u003c\/p\u003e \u003cb\u003eNAWIN C. MISHRA, PhD,\u003c\/b\u003e is an Emeritus Professor of Molecular Genetics and Genomics at the Department of Biological Sciences at the University of South Carolina. Professor Mishra has also served as a scientific consultant to the FAO of the United Nations, as Chairman of the Program Committee of the Genetics Society of America, and on the review panel of the Human Genome Project for the United States DOE. Professor Mishra has published over sixty articles in prominent research journals, including \u003ci\u003eNature\u003c\/i\u003e, the \u003ci\u003eProceedings of the United States National Academy of Sciences,\u003c\/i\u003e and \u003ci\u003eGenetics\u003c\/i\u003e. \u003cb\u003eA world-class, concise guide to all things proteomics\u003c\/b\u003e \u003cp\u003eThis book provides a highly authoritative introduction to the promising and fast-advancing field of proteomics, examining the role proteomics plays in the study of biological systems in general and disease in particular. It helps readers understand the structure, function, and interactions of proteins and how this knowledge is used for identifying diseases and developing new drugs.\u003c\/p\u003e \u003cp\u003eNawin Mishra, a world-renowned speaker and leader in proteomics studies who has worked with the late Nobel Laureate E. L. Tatum when proteomics was in its infancy, offers an expert perspective on the entire field, including:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eEasily accessible overview of the principles of proteomics\u003c\/li\u003e \u003cli\u003eCoverage of real-world, cutting-edge medical applications, including personalized medicine\u003c\/li\u003e \u003cli\u003eClear guidelines on how to operate the complex instrumentation involved in proteomics\u003c\/li\u003e \u003cli\u003eDiscussion of the future of proteomics\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eComplete with handy study questions and assuming only a basic understanding of biology, \u003ci\u003eIntroduction to Proteomics\u003c\/i\u003e is an invaluable reference for novices and research scientists alike.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989465415909,"sku":"NP9780471754022","price":129.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780471754022.jpg?v=1761784211","url":"https:\/\/k12savings.com\/products\/introduction-to-proteomics-isbn-9780471754022","provider":"K12savings","version":"1.0","type":"link"}