{"product_id":"inositol-phospholipid-signaling-in-physiology-and-disease-volume-1280-isbn-9781573318914","title":"Inositol Phospholipid Signaling in Physiology and Disease, Volume 1280","description":"\u003cp\u003eA recent upsurge of research examining inositol phospholipids (IP)—membrane-bound species fundamental to cell signaling—continues underscore the role of this pathway in both normal and disease-associated cellular physiology.  This volume includes a selection of cutting-edge, multidisciplinary reports borne out of the conference “Inositol Phospholipid Signaling in Physiology and Disease” held June 26–27, 2012 at the New York Academy of Sciences in New York City.  Papers include important developments investigating IP signaling in immunology, cancer, inflammation, and metabolic disorders.\u003c\/p\u003e \u003cp\u003eNOTE: \u003ci\u003eAnnals\u003c\/i\u003e volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit: \u003ca href=\"http:\/\/ordering.onlinelibrary.wiley.com\/subs.asp?ref=1749-6632\u0026amp;doi=10.111\/(ISSN)1749-6632\"\u003ehttp:\/\/ordering.onlinelibrary.wiley.com\/subs.asp?ref=1749-6632\u0026amp;doi=10.111\/(ISSN)1749-6632\u003c\/a\u003e.\u003c\/p\u003e \u003cp\u003eACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (\u003ca href=\"http:\/\/www.nyas.org\/\"\u003ewww.nyas.org\u003c\/a\u003e). Members of the New York Academy of Science receive full-text access to Annals online and discounts on print volumes. Please visit \u003ca href=\"http:\/\/www.nyas.org\/MemberCenter\/Join.aspx\"\u003ehttp:\/\/www.nyas.org\/MemberCenter\/Join.aspx\u003c\/a\u003e for more information on becoming a member.\u003c\/p\u003e  \u003cp\u003eIntroduction to Inositol Phospholipid Signaling in Physiology and Disease v\u003cbr\u003e \u003ci\u003eWilliam G. Kerr and Sandra Fernandes\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003ePhosphoinositide 3-kinase and INPP4B in human breast cancer 1\u003cbr\u003e \u003ci\u003eMicka C. Bertucci and Christina A. Mitchell\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eRole of SHIP1 in cancer and mucosal inflammation 6\u003cbr\u003e \u003ci\u003eSandra Fernandes, Sonia Iyer, and William G. Kerr\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eRole of SHIP1 in bone biology 11\u003cbr\u003e \u003ci\u003eSonia Iyer, Bryan S. Margulies, and William G. Kerr\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eAchieving cancer cell death with PI3K\/mTOR-targeted therapies 15\u003cbr\u003e \u003ci\u003eSung Su Yea and David A. Fruman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eChallenges in the clinical development of PI3K inhibitors 19\u003cbr\u003e \u003ci\u003eCristian Massacesi, Emmanuelle di Tomaso, Nathalie Fretault, and Samit Hirawat\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eRules of engagement: distinct functions for the four class I PI3K catalytic isoforms in immunity 24\u003cbr\u003e \u003ci\u003eKlaus Okkenhaug\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eControl of T cell tolerance by phosphatase and tensin homolog 27\u003cbr\u003e \u003ci\u003eAlexandria Huynh and Laurence A. Turka\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eRole of PI3K\/Akt and mTOR complexes in Th17 cell differentiation 30\u003cbr\u003e \u003ci\u003eShigenori Nagai, Yutaka Kurebayashi, and Shigeo Koyasu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eTargeting phosphoinositide 3-kinase δ for the treatment of respiratory diseases 35\u003cbr\u003e \u003ci\u003eSrividya Sriskantharajah, Nicole Hamblin, Sally Worsley, Andrew R. Calver, Edith M. Hessel, and Augustin Amour\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003ePhosphoinositide 3-kinase gamma in T cell biology and disease therapy 40\u003cbr\u003e \u003ci\u003eWai-Ping Fung-Leung\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eInhibition of phosphoinositide 3-kinase γ attenuates inflammation, obesity, and cardiovascular risk factors 44\u003cbr\u003e \u003ci\u003eMatthias P. Wymann and Giovanni Solinas\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eClass III PI3K Vps34: essential roles in autophagy, endocytosis, and heart and liver function 48\u003cbr\u003e \u003ci\u003eNadia Jaber and Wei-Xing Zong\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eInpp4b is a novel negative modulator of osteoclast differentiation and a prognostic locus for human osteoporosis 52\u003cbr\u003e \u003ci\u003eJean Vacher\u003c\/i\u003e\u003c\/p\u003e  \u003cp\u003e\u003cstrong\u003eWilliam G. Kerr\u003c\/strong\u003e, Empire Scholar and Murphy Family Professor of Children's Oncology, Pediatrics and Micriobiology \u0026amp; Immunology, SUNY Upstate Medical University.\u003c\/p\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47989430124773,"sku":"NP9781573318914","price":144.5,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781573318914.jpg?v=1761784073","url":"https:\/\/k12savings.com\/products\/inositol-phospholipid-signaling-in-physiology-and-disease-volume-1280-isbn-9781573318914","provider":"K12savings","version":"1.0","type":"link"}