{"product_id":"innate-immunity-to-pulmonary-infection-isbn-9780470026564","title":"Innate Immunity to Pulmonary Infection","description":"Part of the prestigious Novartis Foundation series, this volume uniquely addresses the use of innate immunity to treat or prevent infectious diseases of the lung.  \u003cp\u003e\u003cb\u003e\u003ci\u003eInnate Immunity to Pulmonary Infection:\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e \u003cul type=\"disc\"\u003e \u003cli\u003eProvides a comprehensive overview of pulmonary infectious diseases, including basic pathology, current and potential therapies, and detailed consideration of the innate biological resistance mechanisms in the lung\u003c\/li\u003e \u003cli\u003eThoroughly examines the major topic of innate immunity in immunology, which is now seen as key to the pathogenesis of and vaccination strategies for infectious diseases\u003c\/li\u003e \u003cli\u003eDescribes the genetic and environmental factors which determine the outcome of infection, such as latency of Tuberculosis, blood stream invasion from local infection, and local target tissue damage\u003c\/li\u003e \u003cli\u003eCovers the roles of cells such as neutrophils, macrophages and dendritic cells and of molecular components such as Toll-like receptors\u003c\/li\u003e \u003cli\u003eDiscusses the clinical applications of the new knowledge regarding innate immunity and how this can be used in both treatment and prevention (vaccination) strategies\u003c\/li\u003e \u003cli\u003eIncludes contributions from an international and interdisciplinary group of experts\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003cb\u003e\u003ci\u003eInnate Immunity to Pulmonary Infection\u003c\/i\u003e\u003c\/b\u003e is an essential resource for researchers in both industry and academia. It is of interest for all those interested in the disciplines of immunology, virology, biology, biotechnology and genetics.\u003c\/p\u003e  Symposium on Innate immunity to pulmonary infection, held at the Wolfson Pavillion, University of Cape Town Medical School, South Africa, 28-30 November 2005.  \u003cp\u003eEditors: \u003ci\u003eDerek J. Chadwick\u003c\/i\u003e (Organizer) and \u003ci\u003eJamie Goode\u003c\/i\u003e.\u003c\/p\u003e \u003cp\u003eThis symposium is based on a proposal made by Siamon Gordon and Gordon Brown.\u003c\/p\u003e \u003cp\u003eChair's introduction (\u003ci\u003eSiamon Gordon\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eLung diseases in South Africa: an overview (\u003ci\u003eEric D. Bateman\u003c\/i\u003e and \u003ci\u003eAnamika Jithoo\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eDiscussion.\u003c\/p\u003e \u003cp\u003eTB epidemiology and human genetics (\u003ci\u003ePaul D. van Helden, Marlo Moller, Chantal Babb, Robin Warren, Gerhard Walzl, Pieter Uys\u003c\/i\u003e and \u003ci\u003eEileen Hoal\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eDiscussion.\u003c\/p\u003e \u003cp\u003eBacterial infections of the lung in normal and immunodeficient patients (\u003ci\u003eDavid P. Speert\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eDiscussion.\u003c\/p\u003e \u003cp\u003ePathogenesis of avian flu H5N1 and SARS (\u003ci\u003eMalik Peiris\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eDiscussion.\u003c\/p\u003e \u003cp\u003eImmunity and tolerance to \u003ci\u003eAspergillus fumigatus\u003c\/i\u003e (\u003ci\u003eClaudia Montagnoli, Silvia Bozza, Roberta Gaziano, Teresa Zelante, Pierluigi Bonifazi, Francesca Sepioni, Silvia Bellocchio, Lucia Pitzurra\u003c\/i\u003e and \u003ci\u003eLuigina Romani\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eDiscussion.\u003c\/p\u003e \u003cp\u003ePentraxins in innate immunity and inflammation (\u003ci\u003eCecilia Garlanda, Barbara Bottazzi, Giovanni Salvatori, Rita De Santis, Alessia Cotena, Livija Deban, Viriginia Maina, Federica Moalli, Andrea Doni\u003c\/i\u003e and \u003ci\u003eAlberto Mantovani\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eDiscussion.\u003c\/p\u003e \u003cp\u003eHow superoxide production by neutrophil leukocytes kills microbes (\u003ci\u003eAnthony W. Segal\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e\u003ci\u003eDiscussion.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eLinking innate to adaptive immunity through dendritic cells (\u003ci\u003eRalph M. Steinman\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eDiscussion.\u003c\/p\u003e \u003cp\u003eMacrophage receptors and innate immunity: insights from dectin-1 (\u003ci\u003eGordon D. Brown\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eDiscussion.\u003c\/p\u003e \u003cp\u003eToll-like receptors and control of mycobacterial infection in mice (\u003ci\u003eBernhard Ryffel, Muazzam Jacobs, Shreemanta Parida, Tania Botha,\u003c\/i\u003e \u003ci\u003eDieudonnée Togbe\u003c\/i\u003e and \u003ci\u003eValerie Quesniaux\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eDiscussion.\u003c\/p\u003e \u003cp\u003ePopulation of lungs by mast cells (\u003ci\u003eT. J. Williams\u003c\/i\u003e and \u003ci\u003eC. L. Weller\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eDiscussion.\u003c\/p\u003e \u003cp\u003eInnate immunity and mucus structure and function (\u003ci\u003eJohn K. Sheehan, Mehmet Kesimer\u003c\/i\u003e and \u003ci\u003eRaymond Pickles\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eDiscussion.\u003c\/p\u003e \u003cp\u003eCollectins and host defence (\u003ci\u003eR. B. Sim, H. Clark, K. Hajela\u003c\/i\u003eand \u003ci\u003eK. R. Mayilyan\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e\u003ci\u003eDiscussion.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eInfections and asthma pathogenesis: a critical role for dendritic cells? (\u003ci\u003eBart N. Lambrecht\u003c\/i\u003e and \u003ci\u003eLeonie S. van Rijt\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e\u003ci\u003eDiscussion.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eInnate and adaptive immunity in lung cancer (\u003ci\u003eL. A. Vella\u003c\/i\u003e and \u003ci\u003eO. J. Finn\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eDiscussion.\u003c\/p\u003e \u003cp\u003eSumming up (\u003ci\u003eSiamon Gordon\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eIndex of Contributors.\u003c\/p\u003e \u003cp\u003eSubject index.\u003c\/p\u003e \"…substantially elucidating recent basic science observations of potentially remarkable importance in understanding human biology.\" (\u003ci\u003eDoody's Health Services\u003c\/i\u003e) \u003cb\u003eThe Novartis Foundation\u003c\/b\u003e is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.  Lung infection is a major cause of morbidity and death in developing, as well as developed, countries. Whereas TB is receiving increasing attention, other aspects of lung infection, many treatable or preventable, are relatively neglected.  \u003cp\u003eThe subject of innate immunity has moved towards the centre of immunology and is key to the pathogenesis of infectious diseases and vaccination strategies. While much has been learnt about cellular and molecular mechanisms of innate resistance to infection, this has led to little application to human diseases.\u003c\/p\u003e \u003cp\u003eThe lung is a key target for environmental pathogens, as well as for opportunistic infection, and could be a fertile source of cells and clinical\/pathological materials to investigate disease in a genetically varied population. Both genetic and environmental factors that determine the outcome of infection (e.g. latency of TB, blood stream invasion from local infection, local target tissue damage) are still poorly understood.\u003c\/p\u003e \u003cp\u003eThis book features contributions from some of the world’s leading scientists and clinicians working on diverse aspects of innate immunity and lung diseases.  The unique discussion sections review the state of the field and provide new insights into the key problems in this important, emerging research area.  The book provides fascinating reading for immunologists and respiratory physiologists.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989425144037,"sku":"NP9780470026564","price":211.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470026564.jpg?v=1761784054","url":"https:\/\/k12savings.com\/products\/innate-immunity-to-pulmonary-infection-isbn-9780470026564","provider":"K12savings","version":"1.0","type":"link"}