{"product_id":"immunoinformatics-isbn-9780470853566","title":"Immunoinformatics","description":"The astounding diversity of the immune system and the complexity of its regulatory pathways makes immunology a combinatorial science. Computational analysis has therefore become an essential element of immunology research and this has led to the creation of the emerging field of immunoinformatics. This book is the first to feature thorough coverage of this new field. \u003cp\u003eImmunoinformatics facilitates the understanding of immune function by modelling the interactions among immunological components. Biological research provides ever deeper insights into the complexity of living organisms while computer science provides an effective means to store and analyse large volumes of complex data. Combining the two fields increases the efficiency of biological research and offers the potential for major advances in the study of biological systems.\u003c\/p\u003e \u003cp\u003eThis book encompasses key developments in immunoinformatics, including immunological databases, sequence analysis, structure modelling, mathematical modelling of the immune system, simulation of laboratory experiments, statistical support for immunological experimentation and immunogenomics.\u003c\/p\u003e \u003cp\u003eThe difficulties in effective application of bioinformatic tools in immunology arise at both ends of the spectrum: most immunologists have only a limited comprehension of sophisticated data analysis and applicability and limitations, while the average computer scientist lacks knowledge of the depth and complexity of biological data. The purpose of this book, therefore, is to present contributions from a multidisciplinary team of biologists and computer scientists to explore the issues related to better understanding of immune function and, in particular, to help apply new computer science methods to immunological research.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eRelated \u003ci\u003eNovartis Foundation symposia\u003c\/i\u003e:\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e247 \u003ci\u003eIn Silico Simulation of Biological Processes\u003c\/i\u003e\u003cbr\u003eChair: Denis Noble\u003c\/p\u003e \u003cp\u003e252 \u003ci\u003eGeneration and effector functions of regulatory lymphocytes\u003c\/i\u003e\u003cbr\u003eChair: Jean-François Bach\u003c\/p\u003e  Chair's Introduction (H. Rammensee).  \u003cp\u003eImmunoinformatics - the new kid in town (V. Brusic \u0026amp; N. Petrovsky).\u003c\/p\u003e \u003cp\u003eThe fututre of computational modelling and prediction systems in clinical immunology (N. Petrovsky, \u003ci\u003eet al\u003c\/i\u003e.).\u003c\/p\u003e \u003cp\u003eImmunoinformatics in personalized medicine (K. Gulukota).\u003c\/p\u003e \u003cp\u003eFrom immunome to vaccine: epitope mapping and vaccine design tools (A. De Groot \u0026amp; W. Martin).\u003c\/p\u003e \u003cp\u003eInsights from MHC-bound peptides (H. Margalit \u0026amp; Y. Altuvia).\u003c\/p\u003e \u003cp\u003eGeneral discussion I.\u003c\/p\u003e \u003cp\u003eComputation vaccinology: quanitative approaches (D. Flower, \u003ci\u003eet al\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eIMGT, the international ImMunoGeneTics information System\u003csup\u003e®\u003c\/sup\u003e, \u003ca href=\"http:\/\/imgt.cines.fr\/\"\u003ehttp:\/\/imgt.cines.fr\u003c\/a\u003e  (M. Lefranc).\u003c\/p\u003e \u003cp\u003eGenerating data for databases—the peptide repertoire of HLA molecules (S. Stevanovic, \u003ci\u003eet al\u003c\/i\u003e.).\u003c\/p\u003e \u003cp\u003eHLA nomenclature and the IMGT\/HLA Sequence Database (S. Marsh).\u003c\/p\u003e \u003cp\u003eFrom immunogenetics to immunomics: functional prospecting of genes and transcripts (C. Schönbach).\u003c\/p\u003e \u003cp\u003eMathematical models of HIV and the immune system (D. Wodarz).\u003c\/p\u003e \u003cp\u003eGeneral discussion II.\u003c\/p\u003e \u003cp\u003eImmunogenomics: towards a digital immune system (S. Beck).\u003c\/p\u003e \u003cp\u003eViral bioinformatics: computational views of host and pathogen (P. Kellam, \u003ci\u003eet al.\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eFinal general discussion\u003c\/p\u003e \u003cp\u003eClosing remarks (H. Rammensee).\u003c\/p\u003e \u003cp\u003eIndex of Contributors.\u003c\/p\u003e \u003cp\u003eSubject Index.\u003c\/p\u003e  The \u003cstrong\u003eNovartis Foundation\u003c\/strong\u003e is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.   The astounding diversity of the immune system and the complexity of its regulatory pathways makes immunology a combinatorial science. Computational analysis has therefore become an essential element of immunology research and this has led to the creation of the emerging field of immunoinformatics. This book is the first to feature thorough coverage of this new field.  \u003cp\u003eImmunoinformatics facilitates the understanding of immune function by modelling the interactions among immunological components. Biological research provides ever deeper insights into the complexity of living organisms while computer science provides an effective means to store and analyse large volumes of complex data. Combining the two fields increases the efficiency of biological research and offers the potential for major advances in the study of biological systems.\u003c\/p\u003e \u003cp\u003eThis book encompasses key developments in immunoinformatics, including immunological databases, sequence analysis, structure modelling, mathematical modelling of the immune system, simulation of laboratory experiments, statistical support for immunological experimentation and immunogenomics.\u003c\/p\u003e \u003cp\u003eThe difficulties in effective application of bioinformatic tools in immunology arise at both ends of the spectrum: most immunologists have only a limited comprehension of sophisticated data analysis and applicability and limitations, while the average computer scientist lacks knowledge of the depth and complexity of biological data. The purpose of this book, therefore, is to present contributions from a multidisciplinary team of biologists and computer scientists to explore the issues related to better understanding of immune function and, in particular, to help apply new computer science methods to immunological research.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e\u003ci\u003eRelated Novartis Foundation symposia:\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e247 In Silico Simulation of Biological Processes\u003c\/p\u003e \u003cp\u003eChair: Denis Noble\u003c\/p\u003e \u003cp\u003e252 Generation and effector functions of regulatory lymphocytes\u003c\/p\u003e \u003cp\u003eChair: Jean-François Bach\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989403484389,"sku":"NP9780470853566","price":211.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470853566.jpg?v=1761783976","url":"https:\/\/k12savings.com\/products\/immunoinformatics-isbn-9780470853566","provider":"K12savings","version":"1.0","type":"link"}