{"product_id":"human-population-genetics-isbn-9780470464670","title":"Human Population Genetics","description":"\u003cp\u003e\u003cb\u003eIntroductory guide to human population genetics and microevolutionary theory\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eProviding an introduction to mathematical population genetics, \u003ci\u003eHuman Population Genetics\u003c\/i\u003e gives basic background on the mechanisms of human microevolution. This text combines mathematics, biology, and anthropology and is best suited for advanced undergraduate and graduate study.\u003c\/p\u003e \u003cp\u003eThorough and accessible, \u003ci\u003eHuman Population Genetics\u003c\/i\u003e presents concepts and methods of population genetics specific to human population study, utilizing uncomplicated mathematics like high school algebra and basic concepts of probability to explain theories central to the field. By describing changes in the frequency of genetic variants from one generation to the next, this book hones in on the mathematical basis of evolutionary theory.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e\u003ci\u003eHuman Population Genetics\u003c\/i\u003e includes:\u003c\/b\u003e\u003c\/p\u003e \u003cul\u003e \u003cli\u003e \u003cp\u003eHelpful formulae for learning ease\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eGraphs and analogies that make basic points and relate the evolutionary process to mathematical ideas\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eGlossary terms marked in boldface within the book the first time they appear\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eIn-text citations that act as reference points for further research\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eExemplary case studies\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eTopics such as Hardy-Weinberg equilibrium, inbreeding, mutation, genetic drift, natural selection, and gene flow\u003c\/p\u003e \u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eHuman Population Genetics\u003c\/i\u003e solidifies knowledge learned in introductory biological anthropology or biology courses and makes it applicable to genetic study.\u003c\/p\u003e \u003cp\u003eNOTE: errata for the first edition can be found at the author's website: http:\/\/employees.oneonta.edu\/relethjh\/HPG\/errata.pdf\u003c\/p\u003e \u003cp\u003eForeword vii\u003c\/p\u003e \u003cp\u003ePreface ix\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Genetic, Mathematical, and Anthropological Background 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eI. The Scope of Population Genetics 2\u003c\/p\u003e \u003cp\u003eII. Genetics Background 5\u003c\/p\u003e \u003cp\u003eIII. Principles of Probability 14\u003c\/p\u003e \u003cp\u003eIV. The Anthropological Connection 17\u003c\/p\u003e \u003cp\u003eV. A Closing Thought 21\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Hardy–Weinberg Equilibrium 23\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eI. Genotype and Allele Frequencies 24\u003c\/p\u003e \u003cp\u003eII. What is Hardy–Weinberg Equilibrium? 30\u003c\/p\u003e \u003cp\u003eIII. The Mathematics of Hardy–Weinberg Equilibrium 31\u003c\/p\u003e \u003cp\u003eIV. Using Hardy–Weinberg Equilibrium 37\u003c\/p\u003e \u003cp\u003eV. Extensions of Hardy–Weinberg Equilibrium 40\u003c\/p\u003e \u003cp\u003eVI. Hardy–Weinberg Equilibrium and Evolution 44\u003c\/p\u003e \u003cp\u003eVII. Summary 45\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Inbreeding 49\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eI. Quantifying Inbreeding 51\u003c\/p\u003e \u003cp\u003eII. Population Genetics and Inbreeding 62\u003c\/p\u003e \u003cp\u003eIII. Inbreeding in Human Populations 65\u003c\/p\u003e \u003cp\u003eIV. Summary 75\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Mutation 77\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eI. The Nature of Mutations 77\u003c\/p\u003e \u003cp\u003eII. Models of Mutation 81\u003c\/p\u003e \u003cp\u003eIII. Mutational History and Anthropological Questions 88\u003c\/p\u003e \u003cp\u003eIV. Summary 96\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Genetic Drift 101\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eI. What is Genetic Drift? 102\u003c\/p\u003e \u003cp\u003eII. Genetic Drift and Population Size 112\u003c\/p\u003e \u003cp\u003eIII. Effects on Genetic Variation 120\u003c\/p\u003e \u003cp\u003eIV. Mutation and Genetic Drift 121\u003c\/p\u003e \u003cp\u003eV. Coalescent Theory 125\u003c\/p\u003e \u003cp\u003eVI. Summary 131\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Models of Natural Selection 139\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eI. How Does Natural Selection Work? 140\u003c\/p\u003e \u003cp\u003eII. A General Model of Natural Selection 145\u003c\/p\u003e \u003cp\u003eIII. Types of Natural Selection 147\u003c\/p\u003e \u003cp\u003eIV. Other Aspects of Selection 160\u003c\/p\u003e \u003cp\u003eV. Summary 167\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Natural Selection in Human Populations 181\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eI. Case Studies of Natural Selection in Human Populations 182\u003c\/p\u003e \u003cp\u003eII. Are Humans Still EvolVIng? 198\u003c\/p\u003e \u003cp\u003eIII. Summary 203\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Gene Flow 205\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eI. The Evolutionary Impact of Gene Flow 206\u003c\/p\u003e \u003cp\u003eII. Models of Gene Flow 208\u003c\/p\u003e \u003cp\u003eIII. Gene Flow and Genetic Drift 213\u003c\/p\u003e \u003cp\u003eIV. Estimating Admixture in Human Populations 226\u003c\/p\u003e \u003cp\u003eV. Summary 230\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Human Population Structure and History 237\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eI. Case Studies of Human Population Structure 238\u003c\/p\u003e \u003cp\u003eII. The Origin of Modern Humans 242\u003c\/p\u003e \u003cp\u003eIII. Case Studies of Population Origins 247\u003c\/p\u003e \u003cp\u003eIV. Summary 255\u003c\/p\u003e \u003cp\u003eGlossary 257\u003c\/p\u003e \u003cp\u003eReferences 267\u003c\/p\u003e \u003cp\u003eIndex 279\u003c\/p\u003e  \u003cp\u003e“Relethford’s Human Population Geneticsis a superb attempt at facing the challenges of explaining the basics of population genetics to those with a limited background in evolutionary theory and a fear of the quantitative.”  (\u003ci\u003eThe Quarterly Review of Biology\u003c\/i\u003e, 1  September 2014)\u003c\/p\u003e \u003cp\u003e“For many students, and likely some instructors, who have found the mathematical underpinnings of evolutionary genetics daunting, this new volume will be a welcome addition to the bookshelf. It is an easy book to recommend either as a primary text in anthropological genetics courses, or as a recommended or adjunct text in upper division\/beginning graduate courses in human biology, human genetics, or human evolution.”  (\u003ci\u003eAmerican Journal of Physical Anthropology\u003c\/i\u003e, 19 September 2013)\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cb\u003eDr. John H. Relethford\u003c\/b\u003e (Distinguished Teaching Professor) is a biological anthropologist who received his Ph.D. in anthropology in 1980 from the State University of New York at Albany. Dr. Relethford's major interests are in the fields of anthropological genetics, human variation, and modern human origins. Much of his research has focused on the reconstruction of history from patterns of modern biological variation. His past work has also included studies of migration, quantitative genetics, child growth, epidemiology, and aging. His current work focuses on two topics, the evolutionary history of Irish populations and the origin of modern humans. \u003cp\u003e\u003cb\u003eIntroductory guide to human population genetics and microevolutionary theory\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eProviding an introduction to mathematical population genetics, \u003ci\u003eHuman Population Genetics\u003c\/i\u003e gives basic background on the mechanisms of human microevolution. This text combines mathematics, biology, and anthropology and is best suited for advanced undergraduate and graduate study.\u003c\/p\u003e \u003cp\u003eThorough and accessible, \u003ci\u003eHuman Population Genetics\u003c\/i\u003e presents concepts and methods of population genetics specific to human population study, utilizing uncomplicated mathematics like high school algebra and basic concepts of probability to explain theories central to the field. By describing changes in the frequency of genetic variants from one generation to the next, this book hones in on the mathematical basis of evolutionary theory.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e\u003ci\u003eHuman Population Genetics\u003c\/i\u003e includes:\u003c\/b\u003e\u003c\/p\u003e \u003cul\u003e \u003cli\u003e \u003cp\u003eHelpful formulae for learning ease\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eGraphs and analogies that make basic points and relate the evolutionary process to mathematical ideas\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eGlossary terms marked in boldface within the book the first time they appear\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eIn-text citations that act as reference points for further research\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eExemplary case studies\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eTopics such as Hardy-Weinberg equilibrium, inbreeding, mutation, genetic drift, natural selection, and gene flow\u003c\/p\u003e \u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eHuman Population Genetics\u003c\/i\u003e solidifies knowledge learned in introductory biological anthropology or biology courses and makes it applicable to genetic study.\u003c\/p\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47989389590757,"sku":"NP9780470464670","price":69.5,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470464670.jpg?v=1761783920","url":"https:\/\/k12savings.com\/products\/human-population-genetics-isbn-9780470464670","provider":"K12savings","version":"1.0","type":"link"}