{"product_id":"human-oral-mucosa-isbn-9780813814865","title":"Human Oral Mucosa","description":"\u003ci\u003eHuman Oral Mucosa: Development, Structure and Function\u003c\/i\u003e is a new text that reflects the considerable increase in knowledge of oral mucosa that has occurred in recent years. Our understanding of the structure of oral mucosa is now established at a molecular rather than a tissue or cellular level. This in turn has revealed a level of function that was previously not suspected, including a sophisticated barrier to the penetration of exogenous materials, and the synthesis of specific antimicrobial compounds, representing components of the innate immune system. There is also a growing realization of commonality in structure and function between regions of oral mucosa and the mucosae of the esophagus and vagina.  \u003cp\u003e The aim of the present volume is to provide a more sophisticated text on human oral mucosa than presently exists in textbooks and to bring together information that is otherwise to be found in separate, specialist volumes into a comprehensive text. It relates structure at the molecular, cellular and tissue level to function and to clinical behavior. The volume is directed to advanced students and researchers in oral biology, as well as those in allied areas of investigation, such as dermatology, gynecology, internal medicine and pathology.\u003c\/p\u003e  \u003cb\u003ePreface vii\u003c\/b\u003e  \u003cp\u003e\u003cb\u003e1 The functions of oral mucosa 3\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 Oral mucosa: What is it and what does it do? 3\u003c\/p\u003e \u003cp\u003e1.2 Functions of the oral mucosa 5\u003c\/p\u003e \u003cp\u003eReferences 7\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 The organization of oral mucosa 9\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 Clinical features 10\u003c\/p\u003e \u003cp\u003e2.2 Component tissues and glands 14\u003c\/p\u003e \u003cp\u003eReferences 16\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Oral epithelium 19\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Histological structure of oral epithelium 20\u003c\/p\u003e \u003cp\u003e3.2 Epithelial proliferation and turnover 24\u003c\/p\u003e \u003cp\u003e3.3 Molecular and cellular organization of oral epithelium 29\u003c\/p\u003e \u003cp\u003e3.4 Non-keratinocytes in the oral epithelium 41\u003c\/p\u003e \u003cp\u003eReferences 50\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 The interface between epithelium and connective tissue 53\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Organization of the normal interface 55\u003c\/p\u003e \u003cp\u003e4.2 Immune-mediated subepithelial blistering diseases (IMSEBDS) 57\u003c\/p\u003e \u003cp\u003eReferences 58\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Connective tissue 59\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Lamina propria 59\u003c\/p\u003e \u003cp\u003e5.2 Blood supply 68\u003c\/p\u003e \u003cp\u003e5.3 Nerve supply 70\u003c\/p\u003e \u003cp\u003eReferences 74\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Regional differences in the oral mucosa 77\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 Structural variations in different regions 77\u003c\/p\u003e \u003cp\u003e6.2 Junctions in the oral mucosa 85\u003c\/p\u003e \u003cp\u003eReferences 97\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Development and aging of the oral mucosa 99\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 Developmental stages of oral mucosa 100\u003c\/p\u003e \u003cp\u003e7.2 The control of mucosal development: epithelial–mesenchymal interaction 104\u003c\/p\u003e \u003cp\u003e7.3 Aging 106\u003c\/p\u003e \u003cp\u003eReferences 109\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Barrier functions of oral mucosa 113\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8.1 The permeability barrier 114\u003c\/p\u003e \u003cp\u003e8.2 Immunologic barrier function of oral mucosa 122\u003c\/p\u003e \u003cp\u003eReferences 135\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Homologies in structure and function among mucosae: oral, esophageal, and vaginal mucosa 145\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9.1 Esophagus 145\u003c\/p\u003e \u003cp\u003e9.2 Vagina 147\u003c\/p\u003e \u003cp\u003e9.3 Organization of the tissues of esophagus and vagina 147\u003c\/p\u003e \u003cp\u003e9.4 Non-keratinocytes in esophageal and vaginal mucosa 153\u003c\/p\u003e \u003cp\u003e9.5 Infl ammatory cells 154\u003c\/p\u003e \u003cp\u003eReferences 154\u003c\/p\u003e \u003cp\u003e\u003cb\u003eIndex 159\u003c\/b\u003e\u003c\/p\u003e  \u003cb\u003eChristopher Squier\u003c\/b\u003e has an international reputation for his research on the structure and function of oral mucosa, being the author or co-author of 200 books, chapters or peer-reviewed articles. He has received the Distinguished Scientist Award in Oral Biology from the International Association for Dental Research.  \u003cp\u003e\u003cb\u003eKim Brogden\u003c\/b\u003e is a professor in the Department of Periodontics and the Dows Institute for Dental Research at the University of Iowa. His work on innate immunity in mucosal diseases including oral mucosa is recognized worldwide and he is the author of over 155 books, chapters or peer reviewed publications.\u003c\/p\u003e  \u003ci\u003eHuman Oral Mucosa: Development, Structure and Function\u003c\/i\u003e is a new text that reflects the considerable increase in knowledge of oral mucosa that has occurred in recent years. Our understanding of the structure of oral mucosa is now established at a molecular rather than a tissue or cellular level. This in turn has revealed a level of function that was previously not suspected, including a sophisticated barrier to the penetration of exogenous materials, and the synthesis of specific antimicrobial compounds, representing components of the innate immune system. There is also a growing realization of commonality in structure and function between regions of oral mucosa and the mucosae of the esophagus and vagina.  \u003cp\u003eThe aim of the present volume is to provide a more sophisticated text on human oral mucosa than presently exists in textbooks and to bring together information that is otherwise to be found in separate, specialist volumes into a comprehensive text. It relates structure at the molecular, cellular and tissue level to function and to clinical behavior. The volume is directed to advanced students and researchers in oral biology, as well as those in allied areas of investigation, such as dermatology, gynecology, internal medicine and pathology.\u003c\/p\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47989389557989,"sku":"NP9780813814865","price":108.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780813814865.jpg?v=1761783921","url":"https:\/\/k12savings.com\/products\/human-oral-mucosa-isbn-9780813814865","provider":"K12savings","version":"1.0","type":"link"}