{"product_id":"human-blood-plasma-proteins-isbn-9780470016749","title":"Human Blood Plasma Proteins","description":"\u003ci\u003eHuman Blood Plasma Proteins\u003c\/i\u003e gives an overview of the proteins found in human blood plasma, with special emphasis on their structure and function and relationship to pathological states and disease. Topics covered include:  \u003cul\u003e \u003cli\u003eintroduction to blood components and blood plasma proteins\u003c\/li\u003e \u003cli\u003eblood plasma protein domains, motifs and repeats\u003c\/li\u003e \u003cli\u003eblood plasma protein families and posttranslational modifications\u003c\/li\u003e \u003cli\u003eblood coagulation and fibrinolysis\u003c\/li\u003e \u003cli\u003ethe complement system\u003c\/li\u003e \u003cli\u003ethe immune system\u003c\/li\u003e \u003cli\u003eenzymes\u003c\/li\u003e \u003cli\u003einhibitors\u003c\/li\u003e \u003cli\u003elipoproteins\u003c\/li\u003e \u003cli\u003ehormones\u003c\/li\u003e \u003cli\u003ecytokines and growth factors\u003c\/li\u003e \u003cli\u003etransport and storage\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThe information of each protein discussed in this book in some detail is summarised at the end of each chapter in a \u003cb\u003eData Sheet\u003c\/b\u003e, where one can find the most important data of each protein at one glance. Full cross-referencing to protein databases is given and many of the proteins discussed are accompanied by their 3D structure.\u003c\/p\u003e \u003cp\u003eAttractively presented in full colour, \u003ci\u003eHuman Blood Plasma Proteins\u003c\/i\u003e is an essential atlas of this proteome for anyone working in biochemistry, protein chemistry and proteomics, structural biology, and medicine.\u003c\/p\u003e  Preface.  \u003cp\u003e\u003cb\u003e1 Introduction.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Blood Components.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 Introduction.\u003c\/p\u003e \u003cp\u003e2.2 Short History.\u003c\/p\u003e \u003cp\u003e2.3 Blood Components.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003eData Sheet.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Blood Plasma Proteins.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction.\u003c\/p\u003e \u003cp\u003e3.2 Short History.\u003c\/p\u003e \u003cp\u003e3.3 Classification of Blood Plasma Proteins.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart II.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Domains, Motifs and Repeats.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction.\u003c\/p\u003e \u003cp\u003e4.2 The Epidermal Growth Factor (EGF)-Like Domain.\u003c\/p\u003e \u003cp\u003e4.3 The Kringle Domain.\u003c\/p\u003e \u003cp\u003e4.4 The g-Carboxyglutamic Acid-Rich (Gla) Domain.\u003c\/p\u003e \u003cp\u003e4.5 The PAN\/Apple Domain.\u003c\/p\u003e \u003cp\u003e4.6 The Sushi\/CCP\/SCR Domain.\u003c\/p\u003e \u003cp\u003e4.7 The Fibronectin Type I, the Fibronectin Type II Collagen-Binding and the Fibronectin Type III Domains.\u003c\/p\u003e \u003cp\u003e4.8 The Coagulation Factors 5\/8 Type C Domain (FA58C).\u003c\/p\u003e \u003cp\u003e4.9 The Thrombospondin Type I Repeat (TSP1).\u003c\/p\u003e \u003cp\u003e4.10 The VWFA, VWFC and VWFD Domains.\u003c\/p\u003e \u003cp\u003e4.11 The Cystatin-Like Domain.\u003c\/p\u003e \u003cp\u003e4.12 The LDL-Receptor Class A (LDLRA) and Class B (LDLRB) Domains.\u003c\/p\u003e \u003cp\u003e4.13 The C-Terminal Cystine Knot (CTCK) Structure.\u003c\/p\u003e \u003cp\u003e4.14 The Anaphylatoxin Domain.\u003c\/p\u003e \u003cp\u003e4.15 The CUB Domain.\u003c\/p\u003e \u003cp\u003e4.16 The NTR Domain.\u003c\/p\u003e \u003cp\u003e4.17 The C-Type Lectin (CTL) Domain.\u003c\/p\u003e \u003cp\u003e4.18 The Ig-Like Domain.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Protein Families.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Introduction.\u003c\/p\u003e \u003cp\u003e5.2 Serine Proteases: The Trypsin Family.\u003c\/p\u003e \u003cp\u003e5.3 Serine Protease Inhibitors (Serpins).\u003c\/p\u003e \u003cp\u003e5.4 The a2-Macroglobulin Family.\u003c\/p\u003e \u003cp\u003e5.5 The Serum Albumin Family.\u003c\/p\u003e \u003cp\u003e5.6 The Pancreatic Trypsin Inhibitor (Kunitz) Family Signature.\u003c\/p\u003e \u003cp\u003e5.7 The Kazal Serine Protease Inhibitors Family Signature.\u003c\/p\u003e \u003cp\u003e5.8 The Multicopper Oxidase Family.\u003c\/p\u003e \u003cp\u003e5.9 The Lipocalin Family.\u003c\/p\u003e \u003cp\u003e5.10 The Globin Family.\u003c\/p\u003e \u003cp\u003e5.11 The Glucagon\/Gastric Inhibitory Polypeptide (GIP)\/Secretin\/Vasoactive Intestinal Peptide (VIP) Family.\u003c\/p\u003e \u003cp\u003e5.12 The Glycoprotein Hormone Family.\u003c\/p\u003e \u003cp\u003e5.13 Membrane Attack Complex Components\/Perforin Signature (The Complement C6\/C7\/C8\/C9 Family).\u003c\/p\u003e \u003cp\u003e5.14 The Lipase Family.\u003c\/p\u003e \u003cp\u003e5.15 Hormone Families and Signatures.\u003c\/p\u003e \u003cp\u003e5.16 Growth Factor Families.\u003c\/p\u003e \u003cp\u003e5.17 Cytokine Families.\u003c\/p\u003e \u003cp\u003e5.18 Interleukin Families and Signatures.\u003c\/p\u003e \u003cp\u003e5.19 The Small Cytokine (Intercrine\/Chemokine) Family and Signature.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Posttranslational Modifications.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction.\u003c\/p\u003e \u003cp\u003e6.2 Databases for Posttranslational Modifications (PTMs).\u003c\/p\u003e \u003cp\u003e6.3 Disulfide Bridges.\u003c\/p\u003e \u003cp\u003e6.4 Glycosylation.\u003c\/p\u003e \u003cp\u003e6.5 Phosphorylation.\u003c\/p\u003e \u003cp\u003e6.6 Hydroxylation.\u003c\/p\u003e \u003cp\u003e6.7 Sulfation.\u003c\/p\u003e \u003cp\u003e6.8 Acylation and Alkylation.\u003c\/p\u003e \u003cp\u003e6.9 Amidation.\u003c\/p\u003e \u003cp\u003e6.10 Carboxylation.\u003c\/p\u003e \u003cp\u003e6.11 Crosslinks.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart III.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Blood Coagulation and Fibrinolysis.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 Introduction.\u003c\/p\u003e \u003cp\u003e7.1.1 Definition of haemostasis.\u003c\/p\u003e \u003cp\u003e7.2 Primary Haemostasis.\u003c\/p\u003e \u003cp\u003e7.3 The Coagulation Cascade.\u003c\/p\u003e \u003cp\u003e7.4 The Fibrinolytic System.\u003c\/p\u003e \u003cp\u003e7.5 The Regulation of Blood Coagulation and Fibrinolysis.\u003c\/p\u003e \u003cp\u003e7.6 The Kinin and Angiotensin\/Renin Systems.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003eData Sheets.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 The Complement System.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8.1 Introduction.\u003c\/p\u003e \u003cp\u003e8.2 The Classical Pathway.\u003c\/p\u003e \u003cp\u003e8.3 The Alternative Pathway.\u003c\/p\u003e \u003cp\u003e8.4 The Terminal Components of the Complement System.\u003c\/p\u003e \u003cp\u003e8.5 Components of Complement Activation.\u003c\/p\u003e \u003cp\u003e8.6 Regulation of the Complement System.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003eData Sheets.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 The Immune System.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9.1 Introduction.\u003c\/p\u003e \u003cp\u003e9.2 Immunoglobulins.\u003c\/p\u003e \u003cp\u003e9.3 Antibody Diversity.\u003c\/p\u003e \u003cp\u003e9.4 Major Histocompatibility Complex (MHC) Proteins.\u003c\/p\u003e \u003cp\u003e9.5 Innate Immune System.\u003c\/p\u003e \u003cp\u003e9.6 Other Proteins.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003eData Sheets.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Enzymes.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e10.1 Introduction.\u003c\/p\u003e \u003cp\u003e10.2 EC 1: Oxidoreductases.\u003c\/p\u003e \u003cp\u003e10.3 EC 2: Transferases.\u003c\/p\u003e \u003cp\u003e10.4 EC 3: Hydrolases.\u003c\/p\u003e \u003cp\u003e10.5 EC 5: Isomerases.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003eData Sheets.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Inhibitors.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11.1 Introduction.\u003c\/p\u003e \u003cp\u003e11.2 Serine Protease Inhibitors (Serpins).\u003c\/p\u003e \u003cp\u003e11.3 Blood Coagulation and Fibrinolysis.\u003c\/p\u003e \u003cp\u003e11.4 The Complement System.\u003c\/p\u003e \u003cp\u003e11.5 General Inhibitors.\u003c\/p\u003e \u003cp\u003e11.6 Other Serpins.\u003c\/p\u003e \u003cp\u003e11.7 Other Inhibitors.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003eData Sheets.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Lipoproteins.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e12.1 Introduction.\u003c\/p\u003e \u003cp\u003e12.2 Enzymes in Lipoprotein Metabolism.\u003c\/p\u003e \u003cp\u003e12.3 Apolipoproteins.\u003c\/p\u003e \u003cp\u003e12.4 LDL and VLDL Receptors.\u003c\/p\u003e \u003cp\u003e12.5 Serum Amyloid A Proteins.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003eData Sheets.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Hormones.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e13.1 Introduction.\u003c\/p\u003e \u003cp\u003e13.2 Pancreatic Hormones.\u003c\/p\u003e \u003cp\u003e13.3 Gastrointestinal Hormones.\u003c\/p\u003e \u003cp\u003e13.4 Calcium-Related Hormones.\u003c\/p\u003e \u003cp\u003e13.5 Hormone-Releasing Factors, Their Trophic Hormones and Related Hormones.\u003c\/p\u003e \u003cp\u003e13.6 Vasopressin and Oxytocin.\u003c\/p\u003e \u003cp\u003e13.7 Natural Opioid Peptides.\u003c\/p\u003e \u003cp\u003e13.8 Vasoactive Peptides.\u003c\/p\u003e \u003cp\u003e13.9 Erythropoietin and Thrombopoietin.\u003c\/p\u003e \u003cp\u003e13.10 Others.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003eData Sheets.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Cytokines and Growth Factors.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e14.1 Introduction.\u003c\/p\u003e \u003cp\u003e14.2 Interleukin Families.\u003c\/p\u003e \u003cp\u003e14.3 Tumour Necrosis Factor Family.\u003c\/p\u003e \u003cp\u003e14.4 The Interferon Family.\u003c\/p\u003e \u003cp\u003e14.5 Chemokines.\u003c\/p\u003e \u003cp\u003e14.6 The Platelet-Derived Growth Factor\/Vascular Endothelial Growth Factor Family.\u003c\/p\u003e \u003cp\u003e14.7 Transforming Growth Factor-b Family.\u003c\/p\u003e \u003cp\u003e14.8 Miscellaneous.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003eData Sheets.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Transport and Storage.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e15.1 Introduction.\u003c\/p\u003e \u003cp\u003e15.2 The Serum Albumin Family.\u003c\/p\u003e \u003cp\u003e15.3 The Globin Family.\u003c\/p\u003e \u003cp\u003e15.4 Iron Transport and Storage.\u003c\/p\u003e \u003cp\u003e15.5 Transport of Hormones, Steroids and Vitamins.\u003c\/p\u003e \u003cp\u003e15.6 Other Transport Proteins in Plasma.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003eData Sheets.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 Additional Proteins.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e16.1 Introduction.\u003c\/p\u003e \u003cp\u003e16.2 Additional Blood Plasma Proteins.\u003c\/p\u003e \u003cp\u003eData Sheets.\u003c\/p\u003e \u003cp\u003eAppendix.\u003c\/p\u003e \u003cp\u003eGlossary.\u003c\/p\u003e \u003cp\u003eIndex.\u003c\/p\u003e \"A major addition to the protein library, with an attractive and authoritative display of critical information about each plasma protein and a color schema of its three-dimensional structure from PDB.\" (\u003ci\u003eThe Quarterly Review of Biology\u003c\/i\u003e, December 2009)  \u003cp\u003eJohann Schaller and Simon Gerber are the authors of Human Blood Plasma Proteins: Structure and Function, published by Wiley.   Human plasma contains the most comprehensive version of the human proteome. The complexity of the ‘plasma proteome’ is quickly understood when one considers all the various forms of blood plasma proteins present in plasma: precursor and mature forms, splice variants, degradation products and of course all combinations of posttranslational modifications.  \u003c\/p\u003e\u003cp\u003e\u003ci\u003eHuman Blood Plasma Proteins\u003c\/i\u003e gives an overview of the proteins found in human blood plasma, with special emphasis on their structure and function and relationship to pathological states and disease. Topics covered include:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eIntroduction to blood components and blood plasma proteins\u003c\/li\u003e \u003cli\u003eBlood plasma protein domains, motifs and repeats\u003c\/li\u003e \u003cli\u003eBlood plasma protein families and posttranslational modifications\u003c\/li\u003e \u003cli\u003eBlood coagulation and fibrinolysis\u003c\/li\u003e \u003cli\u003eThe complement system\u003c\/li\u003e \u003cli\u003eThe immune system\u003c\/li\u003e \u003cli\u003eEnzymes\u003c\/li\u003e \u003cli\u003eInhibitors\u003c\/li\u003e \u003cli\u003eLipoproteins\u003c\/li\u003e \u003cli\u003eHormones\u003c\/li\u003e \u003cli\u003eCytokines and growth factors\u003c\/li\u003e \u003cli\u003eTransport and storage\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThe information of each protein discussed in this book in some detail is summarised at the end of each chapter in a Data Sheet, where one can find the most important data of each protein at one glance. Full cross-referencing to protein databases is given and many of the proteins discussed are accompanied by their 3D structure.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eHuman Blood Plasma Proteins\u003c\/i\u003e is an essential atlas of this proteome for anyone working in biochemistry, protein chemistry and proteomics, structural biology, and medicine.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989387493605,"sku":"NP9780470016749","price":231.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470016749.jpg?v=1761783912","url":"https:\/\/k12savings.com\/products\/human-blood-plasma-proteins-isbn-9780470016749","provider":"K12savings","version":"1.0","type":"link"}