{"product_id":"gut-feelings-isbn-9780262543835","title":"Gut Feelings","description":"\u003cb\u003eDiscover why the gut microbiome holds the keys to human health—and can change the way we understand, treat, and prevent disease.\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003e“A detailed and scientifically rigorous survey . . . gives readers a clearer sense of the current state of medical knowledge.” —\u003ci\u003eThe New York Review of Books\u003c\/i\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003eWe are at the dawn of a new scientific revolution. Our understanding of how to treat and prevent diseases has been transformed by knowledge of the microbiome—the rich ecosystem of microorganisms in and on every human. In \u003ci\u003eGut Feelings\u003c\/i\u003e, Alessio Fasano and Susie Flaherty show why we must go beyond the older, myopic view of microorganisms as our enemies to a broader understanding of the microbiome as a parallel civilization that we need to understand, respect, and engage with for the benefit of our own health.\u003cbr\u003e\u003cbr\u003eRecent advances in understanding the microbiome and its role in human health dovetail with the development of personalized or “precision” medicine to create treatments and prevention programs targeted to the molecular imprint of an individual. Fasano and Flaherty explore the microbiome's part in such diseases as gut inflammatory disorders, obesity, neurological conditions, and cancer, and they explain new research in prebiotics, probiotics, synbiotics, and psychobiotics. They also discuss the microbiome and immune function, including a possible role in COVID-19 treatment.\u003cbr\u003e\u003cbr\u003eBy simultaneously expanding our perspective to encompass large datasets and multiple factors in human health, and narrowing our focus to identify the individual communities in the human microbiome, we will enlarge—and perhaps reinvent—our understanding of how to combat disease and maintain health.Preface vii\u003cbr\u003eI The Wisdom of a Microscopic Species\u003cbr\u003e1 Evolutionary Biology Explains Bacterial\u003cbr\u003eAdaptability 3\u003cbr\u003e2 The Ancestral Microbiome 21\u003cbr\u003e3 Early Factors Influencing the Microbiome 49\u003cbr\u003e4 Cracking the Codes: From the Human Genome\u003cbr\u003eto the Human Microbiome 81\u003cbr\u003e5 Beyond Bacteria: Those Other “Omes” 103\u003cbr\u003e6 The Microbiome Hypothesis: The Epigenetic Role\u003cbr\u003eof the Microbiome 131\u003cbr\u003eII The Microbiome’s Role in Disease\u003cbr\u003e7 The Microbiome and Gut Inflammatory\u003cbr\u003eDisorders 165\u003cbr\u003e8 The Microbiome and Obesity 187\u003cbr\u003e9 The Microbiome and Autoimmunity 207\u003cbr\u003e10 The Microbiome and Neurological and Behavioral\u003cbr\u003eDisorders 237\u003cbr\u003e11 The Microbiome and Environmental\u003cbr\u003eEnteropathy 259\u003cbr\u003e12 The Microbiome and Cancer 273\u003cbr\u003eIII Manipulating the Microbiome to Maintain Health\u003cbr\u003e13 From Association to Causation: A New Approach\u003cbr\u003eto Microbiome Composition and Function in\u003cbr\u003eDisease Development 293\u003cbr\u003e14 Preventive Medicine: Monitoring the Microbiome\u003cbr\u003efor Disease Prediction and Interception 313\u003cbr\u003e15 Treatments for Disease: Prebiotics, Probiotics,\u003cbr\u003eSynbiotics, and Postbiotics 345\u003cbr\u003e16 Microbiome Research in Gut-Brain Axis Diseases:\u003cbr\u003ePsychobiotics 381\u003cbr\u003e17 Artificial Intelligence, Synthetic Biology,\u003cbr\u003eand the Microbiome 391\u003cbr\u003e18 Maintaining a Resilient Microbiome through\u003cbr\u003eOld Age 411\u003cbr\u003e Epilogue: Why Studying Our Microbiome Is\u003cbr\u003eImportant for Our Future 425\u003cbr\u003eAcknowledgments 443\u003cbr\u003eNotes 445Alessio Fasano is the W. Allan Walker Chair of Pediatric Gastroenterology and Nutrition and Professor of Pediatrics at Harvard Medical School. He is also Founder and Director of the Center for Celiac Research and Treatment at Massachusetts General Hospital. Award-winning writer and editor Susie Flaherty is Director of Communications at the Center for Celiac Research and Treatment at Massachusetts General Hospital. Fasano and Flaherty are the authors of \u003ci\u003eGluten Freedom\u003c\/i\u003e.","brand":"The MIT Press","offers":[{"title":"Default Title","offer_id":46303958302949,"sku":"NP9780262543835","price":24.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780262543835.jpg?v=1767728588","url":"https:\/\/k12savings.com\/products\/gut-feelings-isbn-9780262543835","provider":"K12savings","version":"1.0","type":"link"}