{"product_id":"evolution-the-logic-of-biology-isbn-9781118729267","title":"Evolution, the Logic of Biology","description":"\u003cp\u003eBy focusing on the cellular mechanisms that underlie ontogeny, phylogeny and regeneration of complex physiologic traits, \u003ci\u003eEvolution, the Logic of Biology\u003c\/i\u003e demonstrates the use of homeostasis, the fundamental principle of physiology and medicine, as the unifying mechanism for evolution as all of biology. The homeostasis principle can be used to understand how environmental stressors have affected physiologic mechanisms to generate condition-specific novelty through cellular mechanisms. \u003c\/p\u003e \u003cp\u003e\u003ci\u003eEvolution, the Logic of Biology\u003c\/i\u003e allows the reader to understand the vertebrate life-cycle as an intergenerational continuum in support of effective, on-going environmental adaptation. By understanding the principles of physiology from their fundamental unicellular origins, culminating in modern-day metazoans, the reader as student, researcher or practitioner will be encouraged to think in terms of the prevention of disease, rather than in the treatment of disease as the eradication of symptoms.\u003cbr\u003e \u003cbr\u003e By tracing the ontogeny and phylogeny of this and other phenotypic homologies, one can perceive and understand how complex physiologic traits have mechanistically evolved from their simpler ancestral and developmental origins as cellular structures and functions, providing a logic of biology for the first time.\u003c\/p\u003e \u003ci\u003eEvolution, the Logic of Biology \u003c\/i\u003ewill be an invaluable resource for graduate students and researchers studying evolutionary development, medicine and biology, anthropology, comparative and developmental biology, genetics and genomics, and physiology. \u003cp\u003ePreface ix\u003c\/p\u003e \u003cp\u003e1 Introduction 1\u003c\/p\u003e \u003cp\u003e2 On the Fractal Nature of Evolution 13\u003c\/p\u003e \u003cp\u003e3 The Historic Perspective on Paracrinology and Evolution as Lead‐ins to a Systems Biology Approach 23\u003c\/p\u003e \u003cp\u003e4 Evolution of Adipocyte Differentiation Related Protein, or “Oh, the Places You’ll Go” – Theodore Geissel, Aka Dr Seuss 37\u003c\/p\u003e \u003cp\u003e5 Evolutionary Ontology and Epistemology 49\u003c\/p\u003e \u003cp\u003e6 Calcium‐Lipid Epistasis: Like Ouroboros, the Snake, Catching its Tail! 65\u003c\/p\u003e \u003cp\u003e7 The Lung Alveolar Lipofibroblast: An Evolutionary Strategy Against Neonatal Hyperoxic Lung Injury 77\u003c\/p\u003e \u003cp\u003e8 Bio‐Logic 85\u003c\/p\u003e \u003cp\u003e9 Cell Signaling as the Basis for all of Biology 107\u003c\/p\u003e \u003cp\u003e10 Information + Negentropy + Homeostasis = Evolution 119\u003c\/p\u003e \u003cp\u003e11 Vertical Integration of Cytoskeletal Function from Yeast to Human 125\u003c\/p\u003e \u003cp\u003e12 Yet Another Bite of the “Evolutionary” Apple 135\u003c\/p\u003e \u003cp\u003e13 On Eliminating the Subjectivity from Biology: Predictions 165\u003c\/p\u003e \u003cp\u003e14 The Predictive Value of the Cellular Approach to Evolution 173\u003c\/p\u003e \u003cp\u003e15 Homeostasis as the Mechanism of Evolution 189\u003c\/p\u003e \u003cp\u003e16 On the Evolution of Development 201\u003c\/p\u003e \u003cp\u003e17 A Central Theory of Biology 219\u003c\/p\u003e \u003cp\u003e18 Implications of Evolutionary Physiology for Astrobiology 231\u003c\/p\u003e \u003cp\u003e19 Pleiotropy Reveals the Mechanism of Evolutionary Novelty 257\u003c\/p\u003e \u003cp\u003e20 Meta‐Darwinism 267\u003c\/p\u003e \u003cp\u003eIndex 279\u003c\/p\u003e   \u003cp\u003e\u003cb\u003e John S. Torday,\u003c\/b\u003e PhD, is Professor of Pediatrics and Ob\/Gyn, Director of The Henry L. Guenther Laboratory for Cell\/Molecular Research, Director of Laboratory for Evolutionary Preventive Medicine at Harbor-UCLA Medical Center in Torrance, CA, USA and a member of the Faculty in the Evolutionary Medicine Program at the University of California, Los Angeles in Los Angeles, CA, USA.    \u003c\/p\u003e\u003cp\u003e\u003cb\u003e Virender K. Rehan,\u003c\/b\u003e MD, is Professor of Pediatrics and Director of the Neonatal Intensive Care Unit at Harbor-UCLA Medical Center Torrance, CA, USA.      \u003c\/p\u003e\u003cp\u003e By focusing on the cellular mechanisms that underlie ontogeny, phylogeny and regeneration of complex physiologic traits, \u003ci\u003eEvolution, the Logic of Biology\u003c\/i\u003e demonstrates the use of homeostasis, the fundamental principle of physiology and medicine, as the unifying mechanism for evolution as all of biology. The homeostasis principle can be used to understand how environmental stressors have affected physiologic mechanisms to generate condition-specific novelty through cellular mechanisms.   \u003c\/p\u003e\u003cp\u003e\u003ci\u003e Evolution, the Logic of Biology\u003c\/i\u003e allows the reader to understand the vertebrate life-cycle as an intergenerational continuum in support of effective, on-going environmental adaptation. By understanding the principles of physiology from their fundamental unicellular origins, culminating in modern-day metazoans, the reader as student, researcher or practitioner will be encouraged to think in terms of the prevention of disease, rather than in the treatment of disease as the eradication of symptoms.   \u003c\/p\u003e\u003cp\u003e By tracing the ontogeny and phylogeny of this and other phenotypic homologies, one can perceive and understand how complex physiologic traits have mechanistically evolved from their simpler ancestral and developmental origins as cellular structures and functions, providing a logic of biology for the first time.   \u003c\/p\u003e\u003cp\u003e\u003ci\u003e Evolution, the Logic of Biology\u003c\/i\u003e will be an invaluable resource for graduate students and researchers studying evolutionary development, medicine and biology, anthropology, comparative and developmental biology, genetics and genomics, and physiology.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989178630373,"sku":"NP9781118729267","price":160.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781118729267.jpg?v=1761783107","url":"https:\/\/k12savings.com\/products\/evolution-the-logic-of-biology-isbn-9781118729267","provider":"K12savings","version":"1.0","type":"link"}