{"product_id":"evolution-of-virulence-in-eukaryotic-microbes-isbn-9781118038185","title":"Evolution of Virulence in Eukaryotic Microbes","description":"\u003cp\u003e\u003cb\u003eA unique and timely review of the emergence of eukaryotic virulence in fungi, oomycetes, and protozoa, as they affect both animals and plants\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eEvolution of Virulence in Eukaryotic Microbes\u003c\/i\u003e addresses new developments in defining the molecular basis of virulence in eukaryotic pathogens. By examining how pathogenic determinants have evolved in concert with their hosts, often overcoming innate and adaptive immune mechanisms, the book takes a fresh look at the selective processes that have shaped their evolution.\u003c\/p\u003e \u003cp\u003eIntroductory chapters ground the reader in principal evolutionary themes such as phylogenetics and genetic exchange, building a basis of knowledge for later chapters covering advances in genetic tools, how pathogens exchange genetic material in nature, and the common themes of evolutionary adaptation that lead to disease in different hosts.\u003c\/p\u003e \u003cp\u003eWith the goal of linking the research findings of the many disparate scientific communities in the field, the book:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eAssembles for the first time a collection of chapters on the diversity of eukaryotic microorganisms and the influence of evolutionary forces on the origins and emergence of their virulent attributes\u003c\/li\u003e \u003cli\u003eHighlights examples from three important, divergent groups of eukaryotic microorganisms that cause disease in animals and plants: oomycetes, protozoan parasites, and fungi\u003c\/li\u003e \u003cli\u003eCovers how the development of genetic tools has fostered the identification and functional analyses of virulence determinants\u003c\/li\u003e \u003cli\u003eAddresses how pathogens exchange genetic material in nature via classical or modified meiotic processes, horizontal gene transfer, and sexual cycles including those that are cryptic or even unisexual\u003c\/li\u003e \u003cli\u003eProvides a broad framework for formulating future studies by illustrating themes common to different pathogenic microbes\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eEvolution of Virulence in Eukaryotic Microbes\u003c\/i\u003e is an ideal book for microbiologists, evolutionary biologists and medical professionals, as well as graduate students, postdoctoral fellows, and faculty members working on the evolution of pathogens.\u003c\/p\u003e \u003cp\u003ePREFACE ix\u003c\/p\u003e \u003cp\u003eACKNOWLEDGMENTS xi\u003c\/p\u003e \u003cp\u003eCONTRIBUTORS xiii\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART I GENERAL OVERVIEWS 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Population Genetics and Parasite Diversity 3\u003cbr\u003e\u003ci\u003eHsiao-Han Chang, Rachel F. Daniels, and Daniel L. Hartl\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Evolution of Meiosis, Recombination, and Sexual Reproduction in Eukaryotic Microbes 17\u003cbr\u003e\u003ci\u003eWenjun Li, Elizabeth Savelkoul, Joseph Heitman, and John M. Logsdon, Jr.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Phylogenomic Analysis 44\u003cbr\u003e\u003ci\u003eAndrew J. Roger, Martin Kolisko, and Alastair G. B. Simpson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Phylogenetics and Evolution of Virulence in the Kingdom Fungi 70\u003cbr\u003e\u003ci\u003eMonica A. Garcia-Solache and Arturo Casadevall\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART II POPULATION GENETICS AND EVOLUTIONARY APPROACHES 91\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5 Malaria: Host Range, Diversity, and Speciation 93\u003cbr\u003e\u003ci\u003eAnanias A. Escalante and Francisco J. Ayala\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 From Population Genomics to Elucidated Traits in Plasmodium Falciparum 111\u003cbr\u003e\u003ci\u003eSarah K. Volkman, Daniel E. Neafsey, Stephen F. Schaffner, Pardis C. Sabeti, and Dyann F. Wirth\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Selective Sweeps in Human Malaria Parasites 124\u003cbr\u003e\u003ci\u003eXin-zhuan Su and John C. Wootton\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Evolution of Drug Resistance in Fungi 143\u003cbr\u003e\u003ci\u003eJessica A. Hill, Samantha J. Hoot, Theodore C. White, and Leah E. Cowen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Discovery of Extant Sexual Cycles in Human Pathogenic Fungi and Their Roles in the Generation of Diversity and Virulence 168\u003cbr\u003e\u003ci\u003eRichard J. Bennett and Kirsten Nielsen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Worldwide Migrations, Host Shifts, and Reemergence of Phytophthora Infestans, the Plant Destroyer 192\u003cbr\u003e\u003ci\u003eJean Beagle Ristaino\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Experimental and Natural Evolution of the Cryptococcus Neoformans and Cryptococcus Gattii Species Complex 208\u003cbr\u003e\u003ci\u003eAlexander Idnurm and Jianping Xu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 Population Genetics, Diversity, and Spread of Virulence in Toxoplasma Gondii 231\u003cbr\u003e\u003ci\u003eBenjamin M. Rosenthal and James W. Ajioka\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART III FORWARD AND REVERSE GENETIC SYSTEMS FOR DEFINING VIRULENCE 247\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e13 Genetic Crosses in Plasmodium Falciparum: Analysis of Drug Resistance 249\u003cbr\u003e\u003ci\u003eJohn C. Tan and Michael T. Ferdig\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 Genetic Mapping of Virulence in Rodent Malarias 269\u003cbr\u003e\u003ci\u003eRichard Carter and Richard Culleton\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Genetic Mapping of Acute Virulence in Toxoplasma Gondii 285\u003cbr\u003e\u003ci\u003eL. David Sibley and John C. Boothroyd\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16 Virulence in African Trypanosomes: Genetic and Molecular Approaches 307\u003cbr\u003e\u003ci\u003eAnnette Macleod, Liam J. Morrison, and Andy Tait\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17 The Evolution of Antigenic Variation in African Trypanosomes 324\u003cbr\u003e\u003ci\u003eAndrew P. Jackson and J. David Barry\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18 Antigenic Variation, Adherence, and Virulence in Malaria 338\u003cbr\u003e\u003ci\u003eJoseph Smith and Kirk W. Deitsch\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e19 Invasion Ligand Diversity and Pathogenesis in Blood-Stage Malaria 362\u003cbr\u003e\u003ci\u003eManoj T. Duraisingh, Jeffrey D. Dvorin, and Peter R. Preiser\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART IV COMPARATIVE \"OMICS\" APPROACHES TO DEFINING VIRULENCE 385\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e20 Evolution of Virulence in Oomycete Plant Pathogens 387\u003cbr\u003e\u003ci\u003ePaul R. J. Birch, Mary E. Coates, and Jim L. Beynon\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e21 Evolution and Genomics of the Pathogenic Candida Species Complex 404\u003cbr\u003e\u003ci\u003eGeraldine Butler, Michael Lorenz, and Neil A. R. Gow\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e22 Evolution of Entamoeba Histolytica Virulence 422\u003cbr\u003e\u003ci\u003eUpinder Singh and Christopher D. Huston\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e23 Sex and Virulence in Basidiomycete Pathogens 437\u003cbr\u003e\u003ci\u003eGuus Bakkeren, Emilia K. Kruzel, and Christina M. Hull\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e24 Emergence of the Chytrid Fungus Batrachochytrium Dendrobatidis and Global Amphibian Declines 461\u003cbr\u003e\u003ci\u003eMatthew C. Fisher, Jason E. Stajich, and Rhys A. Farrer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e25 Impact of Horizontal Gene Transfer on Virulence of Fungal Pathogens of Plants 473\u003cbr\u003e\u003ci\u003eBarbara J. Howlett and Richard P. Oliver\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e26 Evolution of Plant Pathogenicity in Fusarium Species 485\u003cbr\u003e\u003ci\u003eLi-Jun Ma, H. Corby Kistler, and Martijn Rep\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e27 Genetic, Genomic, and Molecular Approaches to Define Virulence of Aspergillus Fumigatus 501\u003cbr\u003e\u003ci\u003eLaetitia Muszkieta, William J. Steinbach, and Jean-Paul Latge\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e28 Cryptosporidium: Comparative Genomics and Pathogenesis 518\u003cbr\u003e\u003ci\u003eSatomi Kato and Jessica C. Kissinger\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eINDEX 545\u003c\/p\u003e  \u003cp\u003e“It should be of interest to evolutionary biologists, medical microbiologists and plant pathologists at postdoctoral and faculty levels.”  (\u003ci\u003eMicrobiology Today\u003c\/i\u003e, 26 November 2012)\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e\u003cb\u003eDr. David Sibley\u003c\/b\u003e, PhD, is a faculty member at the Washington University School of Medicine, where he teaches graduate courses in microbiology and has served on the steering committee for the Molecular Microbiology program for the past 10 years. In addition to authoring over 150 publications,?Dr. Sibley is an associate editor for \u003ci\u003ePLoS Pathogens\u003c\/i\u003e, edits reviews for \u003ci\u003eCellular Microbiology\u003c\/i\u003e, and serves on the board of reviewing editors for \u003ci\u003eScience\u003c\/i\u003e.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eDr. Barbara Howlett\u003c\/b\u003e, PhD, is a Professor in the School of Botany at the University of Melbourne, specializing in fungal diseases of plants. She serves in an editorial capacity for \u003ci\u003ePLoS Pathogens\u003c\/i\u003e, \u003ci\u003eEukaryotic Cell\u003c\/i\u003e, and the \u003ci\u003eEuropean Journal of Plant Pathology\u003c\/i\u003e.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eDr. Joseph Heitman\u003c\/b\u003e, MD, PhD is currently Chair of the Dept of Molecular Genetics and Microbiology at Duke University. Dr. Heitman has co-authored four other books on the topics of eukayrotic function and pathogenesis, and serves as an editor for numerous?publication including\u003ci\u003eEukaryotic Cell\u003c\/i\u003e, \u003ci\u003eVirulence\u003c\/i\u003e, and the \u003ci\u003eJournal of Molecular Medicine\u003c\/i\u003e.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eA unique and timely review of the emergence of eukaryotic virulence in fungi, oomycetes, and protozoa, as they affect both animals and plants\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eEvolution of Virulence in Eukaryotic Microbes\u003c\/i\u003e addresses new developments in defining the molecular basis of virulence in eukaryotic pathogens. By examining how pathogenic determinants have evolved in concert with their hosts, often overcoming innate and adaptive immune mechanisms, the book takes a fresh look at the selective processes that have shaped their evolution.\u003c\/p\u003e \u003cp\u003eIntroductory chapters ground the reader in principal evolutionary themes such as phylogenetics and genetic exchange, building a basis of knowledge for later chapters covering advances in genetic tools, how pathogens exchange genetic material in nature, and the common themes of evolutionary adaptation that lead to disease in different hosts.\u003c\/p\u003e \u003cp\u003eWith the goal of linking the research findings of the many disparate scientific communities in the field, the book:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eAssembles for the first time a collection of chapters on the diversity of eukaryotic microorganisms and the influence of evolutionary forces on the origins and emergence of their virulent attributes\u003c\/li\u003e \u003cli\u003eHighlights examples from three important, divergent groups of eukaryotic microorganisms that cause disease in animals and plants: oomycetes, protozoan parasites, and fungi\u003c\/li\u003e \u003cli\u003eCovers how the development of genetic tools has fostered the identification and functional analyses of virulence determinants\u003c\/li\u003e \u003cli\u003eAddresses how pathogens exchange genetic material in nature via classical or modified meiotic processes, horizontal gene transfer, and sexual cycles including those that are cryptic or even unisexual\u003c\/li\u003e \u003cli\u003eProvides a broad framework for formulating future studies by illustrating themes common to different pathogenic microbes\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eEvolution of Virulence in Eukaryotic Microbes\u003c\/i\u003e is an ideal book for microbiologists, evolutionary biologists and medical professionals, as well as graduate students, postdoctoral fellows, and faculty members working on the evolution of pathogens.\u003c\/p\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47989179056357,"sku":"NP9781118038185","price":184.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781118038185.jpg?v=1761783108","url":"https:\/\/k12savings.com\/products\/evolution-of-virulence-in-eukaryotic-microbes-isbn-9781118038185","provider":"K12savings","version":"1.0","type":"link"}