{"product_id":"enzybiotics-isbn-9780470376553","title":"Enzybiotics","description":"\u003cp\u003ePresents the latest research and applications for a new, promising approach to fighting infectious diseases\u003c\/p\u003e \u003cp\u003eEnzybiotics is a promising way of fighting bacterial or fungal infectious diseases by using viruses or viral-derived lysins. Drawing from the fields of medicinal chemistry, microbiology, genetics, and biochemistry, this book presents the state of the science in enzybiotics research, fully exploring its emerging therapeutic applications.\u003c\/p\u003e \u003cp\u003eThe book begins with four chapters that review the potential applications, possible advantages, and phylogeny of enzybiotics. Next, the book explores:\u003c\/p\u003e \u003cul\u003e \u003cli\u003e \u003cp\u003eA new approach to controlling infections using Gram-negative bacteria\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eBacteriophage holins and their membrane-disrupting activity\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eAnti-staphylococcal lytic enzymes\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eMembrane-targeted enzybiotics\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eDesign of phage cocktails for therapy from a host-range point of view\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eNovel methods to identify new enzybiotics\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eGenetically modified phages that deliver suicidal genes to target bacteria\u003c\/p\u003e \u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThe authors, all active enzybiotics researchers, offer a variety of perspectives, the benefit of their own hands-on investigations, as well as a thorough review and analysis of the current literature.\u003c\/p\u003e \u003cp\u003eAs more and more bacteria become resistant to antibiotics, the development of new disease-fighting agents has become essential. This book demonstrates the full potential of the emerging field of enzybiotics to control infectious diseases. Moreover, it will serve as a springboard for new research and the development of new therapeutics.\u003c\/p\u003e  PREFACE.  \u003cp\u003eCONTRIBUTORS.\u003c\/p\u003e \u003cp\u003e1 ENZYBIOTICS AND THEIR POTENTIAL APPLICATIONS IN MEDICINE (\u003ci\u003eJan Borysowski and Andrzej Górski\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e2 ADVANTAGES AND DISADVANTAGES IN THE USE OF ANTIBIOTICS OR PHAGES AS THERAPEUTIC AGENTS (\u003ci\u003ePatricia Veiga-Crespo and Tomas G. Villa\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e3 ENZYBIOTICS AS SELECTIVE KILLERS OF TARGET BACTERIA (\u003ci\u003eJuan C. Alonso and Marcelo E. Tolmasky\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e4 PHYLOGENY OF ENZYBIOTICS (\u003ci\u003ePatricia Veiga-Crespo and Tomas G. Villa\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e5 BACTERIOPHAGE LYSINS: THE ULTIMATE ENZYBIOTIC (\u003ci\u003eVincent A. Fischetti\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e6 BACTERIOPHAGE HOLINS AND THEIR MEMBRANEDISRUPTING ACTIVITY (\u003ci\u003eMaría Gasset\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e7 ANTI-STAPHYLOCOCCAL LYTIC ENZYMES (\u003ci\u003eJan Borysowski and Andrzej Górski\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e8 MEMBRANE-TARGETED ENZYBIOTICS (\u003ci\u003eMaría Gasset\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e9 DESIGN OF PHAGE COCKTAILS FOR THERAPY FROM A HOST RANGE POINT OF VIEW (\u003ci\u003eLawrence D. Goodridge\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e10 IDENTIFYING PHAGE LYTIC ENZYMES: PAST, PRESENT, AND FUTURE (\u003ci\u003eJonathan E. Schmitz, Raymond Schuch, and Vincent A. Fischetti\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e11 USE OF GENETICALLY MODIFIED PHAGES TO DELIVER SUICIDAL GENES TO TARGET BACTERIA (\u003ci\u003eLawrence D. Goodridge\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eCONCLUDING REMARKS: THE FUTURE OF ENZYBIOTICS (\u003ci\u003ePatricia Veiga-Crespo and Tomas G. Villa\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eINDEX.\u003c\/p\u003e  \u003cb\u003eTomas G. Villa, PhD\u003c\/b\u003e, is Full Professor of Microbiology and Chair of the Department of Microbiology at the University of Santiago de Compostela, Faculty of Pharmacy (Spain). Dr. Villa has written twenty book chapters and over 160 papers. In addition, he has translated into Spanish several microbiology text books. Dr. Villa is regularly engaged in the teaching of microbiology and biotechnology.  \u003cp\u003e\u003cb\u003ePatricia Veiga-Crespo, PhD\u003c\/b\u003e, is Lecturer of Microbiology and works in the Department of Microbiology at the University of Santiago de Compostela, where she is involved in the study of multi-resistance phenomena and enzybiotics and the teaching of advanced biotechnology and basic microbiology.\u003c\/p\u003e  \u003cp\u003ePresents the latest research and applications for a new, promising approach to fighting infectious diseases\u003c\/p\u003e \u003cp\u003eEnzybiotics is a promising way of fighting bacterial or fungal infectious diseases by using viruses or viral-derived lysins. Drawing from the fields of medicinal chemistry, microbiology, genetics, and biochemistry, this book presents the state of the science in enzybiotics research, fully exploring its emerging therapeutic applications.\u003c\/p\u003e \u003cp\u003eThe book begins with four chapters that review the potential applications, possible advantages, and phylogeny of enzybiotics. Next, the book explores:\u003c\/p\u003e \u003cul\u003e \u003cli\u003e \u003cp\u003eA new approach to controlling infections using Gram-negative bacteria\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eBacteriophage holins and their membrane-disrupting activity\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eAnti-staphylococcal lytic enzymes\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eMembrane-targeted enzybiotics\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eDesign of phage cocktails for therapy from a host-range point of view\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eNovel methods to identify new enzybiotics\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eGenetically modified phages that deliver suicidal genes to target bacteria\u003c\/p\u003e \u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThe authors, all active enzybiotics researchers, offer a variety of perspectives, the benefit of their own hands-on investigations, as well as a thorough review and analysis of the current literature.\u003c\/p\u003e \u003cp\u003eAs more and more bacteria become resistant to antibiotics, the development of new disease-fighting agents has become essential. This book demonstrates the full potential of the emerging field of enzybiotics to control infectious diseases. Moreover, it will serve as a springboard for new research and the development of new therapeutics.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989148680421,"sku":"NP9780470376553","price":143.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470376553.jpg?v=1761782993","url":"https:\/\/k12savings.com\/products\/enzybiotics-isbn-9780470376553","provider":"K12savings","version":"1.0","type":"link"}