{"product_id":"drug-compounding-for-veterinary-professionals-isbn-9781119764960","title":"Drug Compounding for Veterinary Professionals","description":"\u003cb\u003eDrug Compounding for Veterinary Professionals\u003c\/b\u003e \u003cp\u003e\u003cb\u003eSafely, effectively, and legally tailor drug treatments to the needs of your specific veterinary patients with this accessible guide\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eDrug Compounding for Veterinary Professionals\u003c\/i\u003e provides an accessible, easy-to-use guide to all aspects of prescribing individualized mixtures of medications in veterinary practice. Its emphasis on practical knowledge and its discussion of both in-house and external options make it a comprehensive introduction to using compounded medications in animals. It guides practitioners through every step of the process, from formulating a compound to working with outside pharmacists.  \u003c\/p\u003e\u003cp\u003eThe book presents guidance on how to get more information on current regulations, consider the risks and benefits, develop formulations, and more. \u003ci\u003eDrug Compounding  for Veterinary Professionals\u003c\/i\u003e readers will also find: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eFigures and line drawings illustrating effective compounding techniques and concepts\u003c\/li\u003e \u003cli\u003eAn emphasis on practical knowledge for clinical use\u003c\/li\u003e \u003cli\u003eAnswers to frequently asked questions about drug compounding\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003e\u003ci\u003eDrug Compounding for Veterinary Professionals\u003c\/i\u003e is essential for any veterinary  practitioner, veterinary pharmacologist, or student looking to understand this crucial component of patient care. \u003c\/p\u003e\u003cp\u003eForeword xi\u003c\/p\u003e \u003cp\u003ePreface xiii\u003c\/p\u003e \u003cp\u003eList of Acronyms xiv\u003c\/p\u003e \u003cp\u003eAbout the Companion Website xvi\u003c\/p\u003e \u003cp\u003eIntroduction xvii\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Compounding Regulations 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eOrganizations and Regulatory Agencies Involved with Compounding 3\u003c\/p\u003e \u003cp\u003eFood and Drug Administration 3\u003c\/p\u003e \u003cp\u003eUnited States Pharmacopeia 3\u003c\/p\u003e \u003cp\u003eDrug Enforcement Administration 5\u003c\/p\u003e \u003cp\u003eState Boards of Pharmacy 6\u003c\/p\u003e \u003cp\u003eState Veterinary Boards 6\u003c\/p\u003e \u003cp\u003eCompliance Policy Guides and Guidance for Industry Documents 6\u003c\/p\u003e \u003cp\u003eWhat Is Compounding? 7\u003c\/p\u003e \u003cp\u003eThe Food, Drug, and Cosmetic Act 9\u003c\/p\u003e \u003cp\u003eAnimal Medicinal Drug Use Clarification Act 9\u003c\/p\u003e \u003cp\u003ePreparing Compounds from an Approved Product or a Pure Drug Powder 10\u003c\/p\u003e \u003cp\u003eFederal Versus State Law 11\u003c\/p\u003e \u003cp\u003eOffice Use Compounding 12\u003c\/p\u003e \u003cp\u003eDrug Quality and Security Act 13\u003c\/p\u003e \u003cp\u003eFinding Additional Information 13\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Risk–Benefit Analysis of Compounded Medications 17\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eBenefits of Compounded Products 17\u003c\/p\u003e \u003cp\u003eDosage Form 17\u003c\/p\u003e \u003cp\u003eFlavoring 20\u003c\/p\u003e \u003cp\u003eDosage Strength 20\u003c\/p\u003e \u003cp\u003eEliminating Ingredients 21\u003c\/p\u003e \u003cp\u003eAvailability Issues 22\u003c\/p\u003e \u003cp\u003eAppropriate Use of Compounded Medications 22\u003c\/p\u003e \u003cp\u003eFDA-Approved Drugs 23\u003c\/p\u003e \u003cp\u003eCompounded Medication Risks 25\u003c\/p\u003e \u003cp\u003eCompounded (USP) Versus Manufactured (cGMP) 26\u003c\/p\u003e \u003cp\u003eRisks Associated with Compounded Medications – A Look at the Literature 28\u003c\/p\u003e \u003cp\u003eStudies Showing Incorrect Potency 28\u003c\/p\u003e \u003cp\u003eStudies Showing Lack of Stability 31\u003c\/p\u003e \u003cp\u003eStudies Showing Lack of Efficacy 31\u003c\/p\u003e \u003cp\u003eRisks Associated with Specific Types of Compounds 32\u003c\/p\u003e \u003cp\u003eActive Ingredient Source Decisions 34\u003c\/p\u003e \u003cp\u003ePatient-Specific Compounding Versus Office Use Compounding 35\u003c\/p\u003e \u003cp\u003eAdverse Event Reporting 36\u003c\/p\u003e \u003cp\u003eIdentifying Potential Formulation Issues 37\u003c\/p\u003e \u003cp\u003eDrug Recalls 38\u003c\/p\u003e \u003cp\u003eSelecting a Compounding Pharmacy 39\u003c\/p\u003e \u003cp\u003eClient Education 40\u003c\/p\u003e \u003cp\u003eReducing Risk in Practice 40\u003c\/p\u003e \u003cp\u003eConclusion 41\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Beyond-Use Dating 45\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eFactors Considered When Assigning BUDs and Expiration Dates 45\u003c\/p\u003e \u003cp\u003eUSP Default BUDs 48\u003c\/p\u003e \u003cp\u003eStability Studies 49\u003c\/p\u003e \u003cp\u003eEvaluating Stability Studies 50\u003c\/p\u003e \u003cp\u003eDetermining BUDs for In-House Formulations 51\u003c\/p\u003e \u003cp\u003eBUD Considerations When Prescribing Compounded Medications 52\u003c\/p\u003e \u003cp\u003eConclusion 53\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Identifying High-Quality Compounding Pharmacies 55\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eCase Study 1 55\u003c\/p\u003e \u003cp\u003eCase Study 2 58\u003c\/p\u003e \u003cp\u003eWhat to Evaluate 59\u003c\/p\u003e \u003cp\u003eGeneral Practices 59\u003c\/p\u003e \u003cp\u003eStaff Skill Level 61\u003c\/p\u003e \u003cp\u003eFamiliarity with Veterinary Medicine 61\u003c\/p\u003e \u003cp\u003ePharmacy Culture 61\u003c\/p\u003e \u003cp\u003eWays to Evaluate Compounding Pharmacies 62\u003c\/p\u003e \u003cp\u003eLooking Beyond the Pharmacy’s Website 63\u003c\/p\u003e \u003cp\u003eWhat to Look for on a Tour 65\u003c\/p\u003e \u003cp\u003eQuestions to Ask the Pharmacist in Charge 65\u003c\/p\u003e \u003cp\u003eConclusion 67\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Formulation Development 69\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eDosage Forms 69\u003c\/p\u003e \u003cp\u003eOral Administration 69\u003c\/p\u003e \u003cp\u003eOral Solutions 69\u003c\/p\u003e \u003cp\u003eOral Suspensions 70\u003c\/p\u003e \u003cp\u003eOral Syrups 70\u003c\/p\u003e \u003cp\u003eOral Capsules 71\u003c\/p\u003e \u003cp\u003eOral Tablets 72\u003c\/p\u003e \u003cp\u003eOral Treats 73\u003c\/p\u003e \u003cp\u003eOral Emulsions 73\u003c\/p\u003e \u003cp\u003eOral Pastes 74\u003c\/p\u003e \u003cp\u003eOral Powders 74\u003c\/p\u003e \u003cp\u003eTransdermal Administration 74\u003c\/p\u003e \u003cp\u003eTopical Administration 75\u003c\/p\u003e \u003cp\u003eTopical Solutions 75\u003c\/p\u003e \u003cp\u003eTopical Ointments 76\u003c\/p\u003e \u003cp\u003eTopical Shampoos 76\u003c\/p\u003e \u003cp\u003eTopical Mousses 76\u003c\/p\u003e \u003cp\u003eTopical Emulsions 76\u003c\/p\u003e \u003cp\u003eTopical Creams 77\u003c\/p\u003e \u003cp\u003eTopical Gels 77\u003c\/p\u003e \u003cp\u003eOtic Administration 77\u003c\/p\u003e \u003cp\u003eOtic Solutions 77\u003c\/p\u003e \u003cp\u003eOtic Suspensions 77\u003c\/p\u003e \u003cp\u003eOtic Ointments 78\u003c\/p\u003e \u003cp\u003eOther Routes of Administration 78\u003c\/p\u003e \u003cp\u003eRectal Solutions 78\u003c\/p\u003e \u003cp\u003eIntranasal Solutions 78\u003c\/p\u003e \u003cp\u003eInjectable Preparations 78\u003c\/p\u003e \u003cp\u003eOphthalmic Preparations 79\u003c\/p\u003e \u003cp\u003eIngredients 79\u003c\/p\u003e \u003cp\u003eIngredient Selection 79\u003c\/p\u003e \u003cp\u003eSolubility 81\u003c\/p\u003e \u003cp\u003ePartition Coefficient 82\u003c\/p\u003e \u003cp\u003eDensity 83\u003c\/p\u003e \u003cp\u003eWater Activity 83\u003c\/p\u003e \u003cp\u003epH 83\u003c\/p\u003e \u003cp\u003eChelators 84\u003c\/p\u003e \u003cp\u003eAntioxidants 84\u003c\/p\u003e \u003cp\u003ePreservatives 84\u003c\/p\u003e \u003cp\u003eFlavors, Coating Agents, and Sweeteners 85\u003c\/p\u003e \u003cp\u003eColoring Agents 87\u003c\/p\u003e \u003cp\u003eSalt Forms 87\u003c\/p\u003e \u003cp\u003eOrganic Salts 88\u003c\/p\u003e \u003cp\u003eInorganic Salts 88\u003c\/p\u003e \u003cp\u003eCommon Excipients by Dosage Form 89\u003c\/p\u003e \u003cp\u003eOral Liquid Medications 89\u003c\/p\u003e \u003cp\u003eOral Solid Medications 89\u003c\/p\u003e \u003cp\u003eEmulsions 91\u003c\/p\u003e \u003cp\u003eTransdermal Medications 91\u003c\/p\u003e \u003cp\u003eCream, Gel, and Ointment Medications 91\u003c\/p\u003e \u003cp\u003eHazardous Drugs 92\u003c\/p\u003e \u003cp\u003eBeyond-Use Dates 92\u003c\/p\u003e \u003cp\u003eFormulation Resources 93\u003c\/p\u003e \u003cp\u003eCalculations 93\u003c\/p\u003e \u003cp\u003eMeasurements Used in Compounding 96\u003c\/p\u003e \u003cp\u003eDisplacement Factor 96\u003c\/p\u003e \u003cp\u003eCapsules: Packing Statistics 98\u003c\/p\u003e \u003cp\u003ePacking Statistic of Drug 98\u003c\/p\u003e \u003cp\u003eAverage Weight of Ingredients 98\u003c\/p\u003e \u003cp\u003ePercentage of Drug per Capsule Using Bulk Powder 98\u003c\/p\u003e \u003cp\u003ePercentage of Drug per Capsule Using Manufactured Tablets 99\u003c\/p\u003e \u003cp\u003ePercentage\/Amount of Filler per Capsule 101\u003c\/p\u003e \u003cp\u003eConversion to Grams 101\u003c\/p\u003e \u003cp\u003eCompounding Formulations to Avoid 102\u003c\/p\u003e \u003cp\u003eFormulation Development Process 103\u003c\/p\u003e \u003cp\u003eDeveloping a Compounding Formula: Example 1 (USP Compounding Compendium) 104\u003c\/p\u003e \u003cp\u003eDeveloping a Compounding Formula: Example 2 (Stability-Indicating Assay) 106\u003c\/p\u003e \u003cp\u003eCompounding Formulation Assessment 108\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Compounding in House 111\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eDocumentation 111\u003c\/p\u003e \u003cp\u003eMaster Formulation Record 111\u003c\/p\u003e \u003cp\u003eCompounding Record 111\u003c\/p\u003e \u003cp\u003eFormulation Record Components 112\u003c\/p\u003e \u003cp\u003eQuality Assurance and Quality Control 116\u003c\/p\u003e \u003cp\u003eLabeling 118\u003c\/p\u003e \u003cp\u003ePackaging and Storage 119\u003c\/p\u003e \u003cp\u003eCompounding Techniques 120\u003c\/p\u003e \u003cp\u003eTrituration 120\u003c\/p\u003e \u003cp\u003eSifting 121\u003c\/p\u003e \u003cp\u003eGeometric Dilution 121\u003c\/p\u003e \u003cp\u003eWetting 121\u003c\/p\u003e \u003cp\u003eColored Tracers 122\u003c\/p\u003e \u003cp\u003eEquipment 122\u003c\/p\u003e \u003cp\u003eMortars and Pestles 124\u003c\/p\u003e \u003cp\u003eGlassware 125\u003c\/p\u003e \u003cp\u003eContainers 125\u003c\/p\u003e \u003cp\u003eScales 127\u003c\/p\u003e \u003cp\u003eSpatulas and Measuring Devices 129\u003c\/p\u003e \u003cp\u003eEquipment Cleaning 129\u003c\/p\u003e \u003cp\u003eTraining 130\u003c\/p\u003e \u003cp\u003eFormulation Instructions 132\u003c\/p\u003e \u003cp\u003eSpecies-Specific Information 135\u003c\/p\u003e \u003cp\u003eFlavoring 135\u003c\/p\u003e \u003cp\u003eToxicities 136\u003c\/p\u003e \u003cp\u003ePotency Designations 138\u003c\/p\u003e \u003cp\u003eFeasibility for a Veterinary Clinic 139\u003c\/p\u003e \u003cp\u003eIndex 141\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eThe authors\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003e\u003cb\u003eLauren R. Eichstadt Forsythe, PharmD, DICVP,\u003c\/b\u003e is a Clinical Assistant Professor and the Pharmacy Service Head at the University of Illinois Veterinary Teaching Hospital in Urbana, Illinois, USA.  \u003c\/p\u003e\u003cp\u003e\u003cb\u003eAlexandria E. Gochenauer, PharmD, DICVP,\u003c\/b\u003e is a clinical staff pharmacist at the University of Illinois Veterinary Teaching Hospital in Urbana, Illinois, USA.    \u003c\/p\u003e\u003cp\u003e\u003cb\u003eSafely, effectively, and legally tailor drug treatments to the needs of your specific veterinary patients with this accessible guide\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eDrug Compounding for Veterinary Professionals\u003c\/i\u003e provides an accessible, easy-to-use guide to all aspects of prescribing individualized mixtures of medications in veterinary practice. Its emphasis on practical knowledge and its discussion of both in-house and external options make it a comprehensive introduction to using compounded medications in animals. It guides practitioners through every step of the process, from formulating a compound to working with outside pharmacists.  \u003c\/p\u003e\u003cp\u003eThe book presents guidance on how to get more information on current regulations, consider the risks and benefits, develop formulations, and more. \u003ci\u003eDrug Compounding  for Veterinary Professionals\u003c\/i\u003e readers will also find: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eFigures and line drawings illustrating effective compounding techniques and concepts\u003c\/li\u003e \u003cli\u003eAn emphasis on practical knowledge for clinical use\u003c\/li\u003e \u003cli\u003eAnswers to frequently asked questions about drug compounding\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003e\u003ci\u003eDrug Compounding for Veterinary Professionals\u003c\/i\u003e is essential for any veterinary  practitioner, veterinary pharmacologist, or student looking to understand this crucial component of patient care.\u003c\/p\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47989087273189,"sku":"NP9781119764960","price":99.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781119764960.jpg?v=1761782743","url":"https:\/\/k12savings.com\/products\/drug-compounding-for-veterinary-professionals-isbn-9781119764960","provider":"K12savings","version":"1.0","type":"link"}