{"product_id":"dried-blood-spots-isbn-9781118054697","title":"Dried Blood Spots","description":"\u003cp\u003e\u003cb\u003eAn informative and comprehensive book on the applications and techniques of dried blood spot sampling\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eDried blood spot (DBS) sampling involves the collection of a small volume of blood, via a simple prick or other means, from a study subject onto a cellulose or polymer paper card, which is followed by drying and transfer to the laboratory for analysis. For many years, this method of blood sample collection has been extensively utilized in some important areas of human healthcare (for example, newborn screening for inherited metabolic disorders and HIV-related epidemiological studies). Because of its advantages over conventional blood, plasma, or serum sample collection, DBS sampling has been valued by the pharmaceutical industry in drug research and development.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eDried Blood Spots: Applications and Techniques\u003c\/i\u003e features contributions from an international team of leading scientists in the field. Their contributions present a unique resource on the history, principles, procedures, methodologies, applications, and emerging technologies related to DBS.\u003c\/p\u003e \u003cp\u003ePresented in three parts, the book thoroughly examines:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eApplications of DBS sampling and associated procedures and methodologies in various human healthcare studies\u003c\/li\u003e \u003cli\u003eApplications and perspectives of DBS sampling in drug research and development, and therapeutic drug monitoring\u003c\/li\u003e \u003cli\u003eNew technologies and emerging applications related to DBS sampling and analysis\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eDried Blood Spots: Applications and Techniques\u003c\/i\u003e is a valuable working guide for researchers, professionals, and students in healthcare, medical science, diagnostics, clinical chemistry, and pharmaceuticals, etc.\u003c\/p\u003e  \u003cp\u003e\u003ci\u003ePREFACE viii\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eCONTRIBUTORS x\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART I HISTORY, APPLICATIONS, AND HEALTHCARE\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Overview of the History and Applications of Dried Blood Samples 3\u003cbr\u003e \u003ci\u003eW. Harry Hannon and Bradford L. Therrell, Jr.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Dried Blood Spot Cards 16\u003cbr\u003e \u003ci\u003eBrad Davin and W. Harry Hannon\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Dried Blood Spot Sample Collection, Storage, and Transportation 21\u003cbr\u003e \u003ci\u003eJoanne Mei\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Dried Blood Spot Specimens for Polymerase Chain Reaction in Molecular Diagnostics and Public Health Surveillance 32\u003cbr\u003e \u003ci\u003eChunfu Yang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Application of Enzyme Immunoassay Methods Using Dried Blood Spot Specimens 40\u003cbr\u003e \u003ci\u003eMireille B. Kalou\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Applications of Dried Blood Spots in Newborn and Metabolic Screening 53\u003cbr\u003e \u003ci\u003eDonald H. Chace, Alan R. Spitzer, and Víctor R. De Jesús\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Dried Blood Spots for Use in HIV-Related Epidemiological Studies in Resource-Limited Settings 76\u003cbr\u003e \u003ci\u003eSridhar V. Basavaraju and John P. Pitman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Use of Dried Blood Spot Samples in HCV-, HBV-, and Influenza-Related Epidemiological Studies 95\u003cbr\u003e \u003ci\u003eHarleen Gakhar and Mark Holodniy\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Applications of Dried Blood Spots in General Human Health Studies 114\u003cbr\u003e \u003ci\u003eEleanor Brindle, Kathleen A. O’Connor, and Dean A. Garrett\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Applications of Dried Blood Spots in Environmental Population Studies 130\u003cbr\u003e \u003ci\u003eAntonia M. Calafat and Kayoko Kato\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 The Use of Dried Blood Spots and Stains in Forensic Science 140\u003cbr\u003e \u003ci\u003eDonald H. Chace and Nicholas T. Lappas\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART II PHARMACEUTICAL APPLICATIONS\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e12 Pharmaceutical Perspectives of Use of Dried Blood Spots 153\u003cbr\u003e \u003ci\u003eChristopher Evans and Neil Spooner\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Punching and Extraction Techniques for Dried Blood Spot Sample Analysis 160\u003cbr\u003e \u003ci\u003ePhilip Wong and Christopher A. James\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 Considerations in Development and Validation of LC-MS\/MS Method for Quantitative Analysis of Small Molecules in Dried Blood Spot Samples 168\u003cbr\u003e \u003ci\u003eWenkui Li\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Challenges and Experiences with Dried Blood Spot Technology for Method Development and Validation 179\u003cbr\u003e \u003ci\u003eChester L. Bowen and Christopher A. Evans\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16 Clinical Implications of Dried Blood Spot Assays for Biotherapeutics 188\u003cbr\u003e \u003ci\u003eMatthew E. Szapacs and Jonathan R. Kehler\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17 Potential Role for Dried Blood Spot Sampling and Bioanalysis in Preclinical Studies 195\u003cbr\u003e \u003ci\u003eQin C. Ji and Laura Patrone\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18 Clinical and Bioanalytical Evaluation of Dried Blood Spot Sampling for Genotyping and Phenotyping of Cytochrome p450 Enzymes in Healthy Volunteers 202\u003cbr\u003e \u003ci\u003eTheo de Boer, Izaak den Daas, Jaap Wieling, Johan Wemer, and LingSing Chen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e19 Application of Dried Blood Spot Sampling in Clinical Pharmacology Trials and Therapeutic Drug Monitoring 216\u003cbr\u003e \u003ci\u003eKenneth Kulmatycki, Wenkui Li, Xiaoying (Lucy) Xu, and Venkateswar Jarugula\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e20 Automation in Dried Blood Spot Sample Collection, Processing, and Analysis for Quantitative Bioanalysis in Pharmaceutical Industry 229\u003cbr\u003e \u003ci\u003eLeimin Fan, Katty Wan, Olga Kavetskaia, and Huaiqin Wu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e21 Beyond Dried Blood Spots—Application of Dried Matrix Spots 235\u003cbr\u003e \u003ci\u003eShane R. Needham\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART III NEW TECHNOLOGIES AND EMERGING APPLICATIONS\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e22 Direct Analysis of Dried Blood Spot Samples 245\u003cbr\u003e \u003ci\u003ePaul Abu-Rabie\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e23 Paper Spray Ionization for Direct Analysis of Dried Blood Spots 298\u003cbr\u003e \u003ci\u003eJiangjiang Liu, Nicholas E. Manicke, R. Graham Cooks, and Zheng Ouyang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e24 Direct Solvent Extraction and Analysis of Biomarkers in Dried Blood Spots Using a Flow-Through Autosampler 314\u003cbr\u003e \u003ci\u003eDavid S. Millington, Haoyue Zhang, M. Arthur Moseley, J. Will Thompson, and Peter Smith\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e25 Development of Biomarker Assays for Clinical Diagnostics Using a Digital Microfluidics Platform 325\u003cbr\u003e \u003ci\u003eDavid S. Millington, Ramakrishna Sista, Deeksha Bali, Allen E. Eckhardt, and Vamsee Pamula\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e26 Applications and Chemistry of Cellulose Papers for Dried Blood Spots 332\u003cbr\u003e \u003ci\u003eJacquelynn Luckwell, Åke Danielsson, Barry Johnson, Sarah Clegg, Mark Green, and Alan Pierce\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e27 Derivatization Techniques in Dried Blood Spot Analysis 344\u003cbr\u003e \u003ci\u003eAnn-Sofie M.E. Ingels, Nele Sadones, Pieter M.M. De Kesel, Willy E. Lambert, and Christophe P. Stove\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eINDEX 355\u003c\/i\u003e\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eWENKUI LI\u003c\/b\u003e currently serves as Senior Fellow in the Department of Drug Metabolism \u0026amp; Pharmacokinetics at Novartis Institutes for BioMedical Research, where he focuses on regulated LC-MS\/MS bioanalysis for the toxicokinetic and pharmacokinetic assessment of drug candidates. Dr. Li is a member of the editorial board of \u003ci\u003eBiomedical Chromatography\u003c\/i\u003e.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eMIKE S. LEE\u003c\/b\u003e currently serves as a provider of consulting services specializing in pharmaceutical analysis, accelerated drug discovery and development strategies, and analytical technologies. He has delivered many presentations as invited speaker, plenary speaker, and workshops instructor in the areas of drug discovery and development at universities, conferences, and industrial technical centers. He has published numerous papers and books and obtained two U.S. patents.\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eAn informative and comprehensive book on the applications and techniques of dried blood spot sampling\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eDried blood spot (DBS) sampling involves the collection of a small volume of blood, via a simple prick or other means, from a study subject onto a cellulose or polymer paper card, which is followed by drying and transfer to the laboratory for analysis. For many years, this method of blood sample collection has been extensively utilized in some important areas of human healthcare (for example, newborn screening for inherited metabolic disorders and HIV-related epidemiological studies). Because of its advantages over conventional blood, plasma, or serum sample collection, DBS sampling has been valued by the pharmaceutical industry in drug research and development.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eDried Blood Spots: Applications and Techniques\u003c\/i\u003e features contributions from an international team of leading scientists in the field. Their contributions present a unique resource on the history, principles, procedures, methodologies, applications, and emerging technologies related to DBS.\u003c\/p\u003e \u003cp\u003ePresented in three parts, the book thoroughly examines:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eApplications of DBS sampling and associated procedures and methodologies in various human healthcare studies\u003c\/li\u003e \u003cli\u003eApplications and perspectives of DBS sampling in drug research and development, and therapeutic drug monitoring\u003c\/li\u003e \u003cli\u003eNew technologies and emerging applications related to DBS sampling and analysis\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eDried Blood Spots: Applications and Techniques\u003c\/i\u003e is a valuable working guide for researchers, professionals, and students in healthcare, medical science, diagnostics, clinical chemistry, and pharmaceuticals, etc.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989085503717,"sku":"NP9781118054697","price":144.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781118054697.jpg?v=1761782735","url":"https:\/\/k12savings.com\/products\/dried-blood-spots-isbn-9781118054697","provider":"K12savings","version":"1.0","type":"link"}