Determination of Organic Reaction Mechanisms

This practical handbook presents concise descriptions of the most commonly employed experimental techniques for studying reaction mechanisms in organic chemistry. For each technique, all necessary theoretical background is covered, and at least one example of its application--taken from the research literature--is described in detail. Philosophy.

Isotopic Labeling.

Chirality and Stereochemistry.

Kinetics.

Isotope Effects.

Mechanisms of Acid-Base Reactions.

Interpretation of Activation Parameters.

Direct Detection of Reactive Intermediates.

Detailed Case Histories.

Appendixes.

Index.

DAVID O. CARPENTER is a public health physician. His research focuses on human diseases resulting from exposure to environmental contaminants. Following positions at the National Institute of Mental Health and the Armed Forces Radiobiology Research Institute, Dr. Carpenter joined the New York State Department of Health as Director of the Wadsworth Center for Laboratories and Research. He helped create and became the first Dean of the School of Public Health, a collaborative endeavor of the University at Albany and the New York State Department of Health. Upon stepping down as Dean, Dr. Carpenter founded the Institute for Health and the Environment. In 2011, the Institute was named a Collaborating Centre of the World Health Organization in Environmental Health.