{"product_id":"dendrimer-based-drug-delivery-systems-isbn-9780470460054","title":"Dendrimer-Based Drug Delivery Systems","description":"\u003cp\u003eThe opportunities and challenges of using dendrimers to improve drug delivery\u003c\/p\u003e \u003cp\u003eAmong pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest. In particular, researchers have noted that the volume of a dendrimer increases when it has a positive charge. If this property can be applied effectively, dendrimers have enormous potential in drug delivery systems, directly supplying medication to targeted human organs.\u003c\/p\u003e \u003cp\u003eWith contributions from an international team of pioneers and experts in dendrimer research, this book provides a comprehensive overview of the latest research efforts in designing and optimizing dendrimer-based drug delivery systems. The book analyzes key issues, demonstrating the critical connections that link fundamental concepts, design, synthesis, analytical methodology, and biological assessment to the practical use of dendrimers in drug delivery applications. Topics covered include:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eDendrimer history\u003c\/li\u003e \u003cli\u003eSynthesis\u003c\/li\u003e \u003cli\u003ePhysicochemical properties\u003c\/li\u003e \u003cli\u003ePrinciples of drug delivery\u003c\/li\u003e \u003cli\u003eApplications in diverse biomedical fields\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eDendrimer-Based Drug Delivery Systems\u003c\/i\u003e reflects the authors' thorough review and analysis of the current literature as well as their own firsthand experience in the lab. Readers will not only discover the current state of the science, but also gain valuable insights into fruitful directions for future research. References at the end of each chapter serve as a gateway to the growing body of literature in the field, enabling readers to explore each individual topic in greater depth.\u003c\/p\u003e \u003cp\u003ePharmaceutical and biomedical researchers will find this book a unique and essential guide to the opportunities, issues, and challenges involved in fully exploiting the potential of dendrimers to improve drug delivery.\u003c\/p\u003e  \u003cp\u003eForeword vii\u003cbr\u003e \u003ci\u003eDonald A. Tomalia\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003ePreface ix\u003c\/p\u003e \u003cp\u003eAcknowledgments xi\u003c\/p\u003e \u003cp\u003eContributors xiii\u003c\/p\u003e \u003cp\u003eAbout the Editor xvii\u003c\/p\u003e \u003cp\u003e1 Dendrimer Chemistry: Supramolecular Perspectives and Applications 1\u003cbr\u003e \u003ci\u003eCharles N. Moorefield, Sujith Perera, and George R. Newkome\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Physicochemical Properties of Dendrimers and Dendrimer Complexes 55\u003cbr\u003e \u003ci\u003eToyoko Imae\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 The Use of Dendrimers to Optimize the Physicochemical and Therapeutic Properties of Drugs 93\u003cbr\u003e \u003ci\u003eNicole Stieger, Wilna Liebenberg, Marique E. Aucamp, and Melgardt M. de Villiers\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Biological Properties of Phosphorus Dendrimers 139\u003cbr\u003e \u003ci\u003eAnne-Marie Caminade and Jean-Pierre Majoral\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Dendrimer-Based Prodrugs: Synthesis and Biological Evaluation 157\u003cbr\u003e \u003ci\u003eMohammad Najlah, Zhengyuan Zhou, and Antony D’Emanuele\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Improving the Biocompatibility of Dendrimers in Drug Delivery 207\u003cbr\u003e \u003ci\u003eYiwen Li, Libo Zhao, and Yiyun Cheng\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Degradable Dendrimers for Drug Delivery 239\u003cbr\u003e \u003ci\u003eMarc Gingras and Myriam Roy\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Design of Stimuli-Responsive Dendrimers for Biomedical Purposes 307\u003cbr\u003e \u003ci\u003eChie Kojima\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Dendrimer-Based Gene Delivery Systems: Administration Routes and In Vivo Evaluation 329\u003cbr\u003e \u003ci\u003eSantander-Ortega M.J., Uchegbu I.F., and Scha¨tzlein A.G.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Triazine Dendrimers for DNA and siRNA Delivery: Progress, Challenges, and Opportunities 355\u003cbr\u003e \u003ci\u003eMeredith A. Mintzer, Olivia M. Merkel, Thomas Kissel, and Eric E. Simanek\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Dendrimer-Coated Carbohydrate Residues as Drug Delivery Trojan Horses in Glycoscience 407\u003cbr\u003e \u003ci\u003eYoann M. Chabre and Rene´ Roy\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 Nuclear Magnetic Resonance Techniques in the Analysis of Pamam Dendrimer-Based Drug Delivery Systems 439\u003cbr\u003e \u003ci\u003eXueyan Feng, Kun Yang, Jingjing Hu, Tongwen Xu, and Yiyun Cheng\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Dendrimer-Based Medical Nanodevices for Magnetic Resonance Imaging Applications 463\u003cbr\u003e \u003ci\u003eHongdong Cai, Mingwu Shen, and Xiangyang Shi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 Dendrimer-Related Nanoparticle System for Computed Tomography Imaging 479\u003cbr\u003e \u003ci\u003eChen Peng and Xiangyang Shi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 501\u003c\/p\u003e  \u003cp\u003e“This book should be particularly valuable for everyone working in the dendrimer area, but also for researchers in drug delivery and pharmaceutical sciences more generally. To my mind, it is clearly a book to have on your shelf!.”  (\u003ci\u003eChemMedChem\u003c\/i\u003e, 1 March 2013)\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eYIYUN CHENG, PhD,\u003c\/b\u003e is a Full Professor of Biomedical Engineering at the School of Life Science of East China Normal University. His research interests focus on the biomedical applications of dendrimers and other dendritic polymers. Dr. Cheng has published more than forty peer-reviewed manuscripts in such journals as \u003ci\u003eNature Materials, Chemical Society Reviews,\u003c\/i\u003e and \u003ci\u003eJournal of the American Chemical Society.\u003c\/i\u003e\u003c\/p\u003e  \u003cp\u003eThe opportunities and challenges of using dendrimers to improve drug delivery\u003c\/p\u003e \u003cp\u003eAmong pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest. In particular, researchers have noted that the volume of a dendrimer increases when it has a positive charge. If this property can be applied effectively, dendrimers have enormous potential in drug delivery systems, directly supplying medication to targeted human organs.\u003c\/p\u003e \u003cp\u003eWith contributions from an international team of pioneers and experts in dendrimer research, this book provides a comprehensive overview of the latest research efforts in designing and optimizing dendrimer-based drug delivery systems. The book analyzes key issues, demonstrating the critical connections that link fundamental concepts, design, synthesis, analytical methodology, and biological assessment to the practical use of dendrimers in drug delivery applications. Topics covered include:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eDendrimer history\u003c\/li\u003e \u003cli\u003eSynthesis\u003c\/li\u003e \u003cli\u003ePhysicochemical properties\u003c\/li\u003e \u003cli\u003ePrinciples of drug delivery\u003c\/li\u003e \u003cli\u003eApplications in diverse biomedical fields\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eDendrimer-Based Drug Delivery Systems\u003c\/i\u003e reflects the authors' thorough review and analysis of the current literature as well as their own firsthand experience in the lab. Readers will not only discover the current state of the science, but also gain valuable insights into fruitful directions for future research. References at the end of each chapter serve as a gateway to the growing body of literature in the field, enabling readers to explore each individual topic in greater depth.\u003c\/p\u003e \u003cp\u003ePharmaceutical and biomedical researchers will find this book a unique and essential guide to the opportunities, issues, and challenges involved in fully exploiting the potential of dendrimers to improve drug delivery.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989039399141,"sku":"NP9780470460054","price":216.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470460054.jpg?v=1761782543","url":"https:\/\/k12savings.com\/products\/dendrimer-based-drug-delivery-systems-isbn-9780470460054","provider":"K12savings","version":"1.0","type":"link"}