{"product_id":"dark-art-of-blood-cultures-isbn-9781555819811","title":"Dark Art of Blood Cultures","description":"\u003cp\u003eIn the clinical microbiology laboratory, blood is a critical diagnostic sample that, in the majority of cases is sterile (or is it?). However, when microbes gain access to and multiply in the bloodstream, it can result in life-threatening illness including sepsis. Mortality rates from bloodstream infection and sepsis range from 25% to 80%, killing millions of people annually. Blood cultures are a vital technology used in the microbiology laboratory to isolate and identify microbes and predict their response to antimicrobial therapy.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eThe Dark Art of Blood Cultures\u003c\/i\u003e, edited by Wm. Michael Dunne, Jr., and Carey-Ann D. Burnham, surveys the entire field of blood culture technology, providing valuable information about every phase of the process, from drawing samples to culture methods to processing positive cultures. \u003ci\u003eThe Dark Art of Blood Cultures\u003c\/i\u003e is organized around several major topics.\u003c\/p\u003e \u003cul\u003e \u003cli\u003eHistory of blood culture methods. Details the timeline of blood culture methods from manual through automated and describes the technological development of the leading automated blood culture systems (Bactec, BacT\/Alert, and VersaTREK).\u003c\/li\u003e \u003cli\u003eManual and automated blood culture methods. Critiques manual and automated methods for setting up blood cultures for adult and pediatric patients.\u003c\/li\u003e \u003cli\u003eDetection of pathogens directly from blood specimens. Describes currently available CE marked and FDA-cleared commercial tests using both phenotypic and genotypic markers, including their strengths and limitations.\u003c\/li\u003e \u003cli\u003eThe workflow of culturing blood. Includes best practices from specimen collection to culture system verification, processing positive cultures for microbe identification and antibiotic susceptibility determination, along with the epidemiology of positive blood cultures and the value of postmortem blood cultures.\u003c\/li\u003e \u003cli\u003eMicroorganisms in the blood. Examines the concept of a blood microbiome in healthy and diseased individuals.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eThe Dark Art of Blood Cultures\u003c\/i\u003e is a resource that clinicians, laboratorians, lab directors, and hospital administrators will find engaging and extremely useful.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e \u003cp\u003eIf you are looking for online access to the latest clinical microbiology content, please visit \u003ca href=\"http:\/\/www.wiley.com\/learn\/clinmicronow\"\u003ewww.wiley.com\/learn\/clinmicronow\u003c\/a\u003e.\u003c\/p\u003e \u003cp\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e \u003cp\u003eContributors\u003c\/p\u003e \u003cp\u003eForeword\u003c\/p\u003e \u003cp\u003ePreface\u003c\/p\u003e \u003cp\u003eAcknowledgments\u003c\/p\u003e \u003cp\u003eAbout the Editors\u003c\/p\u003e \u003cp\u003e\u003cb\u003eI Perspectives on the Art and Science of Blood Culture \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Historical Perspectives on the Art and Science of Blood Culture \u003cbr\u003e \u003ci\u003eWilliam Michael Dunne, Jr.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Conventional Blood Culture Methods \u003cbr\u003e \u003ci\u003eRobyn Atkinson-Dunn and William Michael Dunne, Jr.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Lysis-Centrifugation Methods of Blood Culture \u003cbr\u003e \u003ci\u003eErin McElvania TeKippe and Morgan A. Pence\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 BACTEC Blood Culture Systems \u003cbr\u003e \u003ci\u003eRobin R. Chamberland\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eII Modern Methods in Blood Culture \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5 The BioMérieux BacT\/ALERT: Automation at Last in the Black Box \u003cbr\u003e \u003ci\u003eBradley Ford and George Kallstrom\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 TREK Blood Culture Systems \u003cbr\u003e \u003ci\u003eNeil W. Anderson and Melanie Yarbrough\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Molecular Methods for Detection of Pathogens Directly from Blood Specimens \u003cbr\u003e \u003ci\u003eMark D. Gonzalez and Robert C. Jerris\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Pediatric Blood Cultures\u003cbr\u003e \u003ci\u003ePaula Revell and Christopher Doern\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Epidemiology of Bloodstream Infections \u003cbr\u003e \u003ci\u003eAllison R. McMullen, Craig B. Wilen, and Carey-Ann D. Burnham\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Best Practices in Blood Cultures\u003cbr\u003e \u003ci\u003eRobert J. Tibbetts and Barbara Robinson-Dunn\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Processing Positive Cultures \u003cbr\u003e \u003ci\u003eMatthew L. Faron and Nathan A. Ledeboer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 Fungal and Mycobacterial Blood Cultures \u003cbr\u003e \u003ci\u003eRobert S. Liao and William Lainhart\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eIV New Developments in Blood Culture \u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e13 The Bacterial Blood Microbiota\/Microbiome \u003cbr\u003e \u003ci\u003eEileen M. Burd and Lars F. Westblade\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex\u003c\/p\u003e   \u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003eAt A Glance\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003eUnderstanding the diagnostic methods necessary to identify bloodstream infections.\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003eDescription\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003eThis book covers the history of blood cultures, from the first inkling of \"germs\" in the mid-1600s to the highly automated systems of today.\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003ePurpose\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003eThe purpose is to provide a dedicated book on the evolution of blood culture technology. These worthy objectives are well met.\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003eAudience\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003eThe audience includes those interested in blood culture technology. It would be of great interest to practicing clinical microbiologists at all levels (bench to doctoral level laboratory directors). Generalist clinical laboratory scientists, generalist laboratory medicine residents, or a subset of technologically savvy infectious disease fellows or practitioners would also enjoy it. The authors are luminaries in the field of clinical microbiology.\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003eFeatures\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003eThis physically small book contains 320 pages of everything you might want to know about blood cultures. For anyone with two or more decades of experience in the clinical microbiology laboratory, this is truly a walk down memory lane. A real strength is the dedicated focus on different commercially available blood culture systems. If you're in the market for a new blood culture system, this is the book best suited to help you understand their different strengths and weaknesses and inform your choice. Another delight is the inclusion of very practical protocols for how to verify instrument performance in your laboratory, concisely summarized from a variety of professional societies or authoritative standards organizations. The book even has a broad and relatively current discussion of molecular methods for rapid identification and antimicrobial susceptibility testing, albeit without an analysis of cost-effectiveness. A few very, very minor issues: chapter 1, figure 4 did not reproduce well and the didactic point is not obvious. Chapter 9, figure 2 — black font on a dark color background is illegible (what are the organisms in dark squares - e.g. #10 for 1995-2002, #8 for 2014-2015?). I highly recommend high contrast font and background colors for the next edition. A few topics are missing - \"time to positivity\" for distinguishing colonized indwelling lines from true bacteremia, the incremental yield of each additional set of blood cultures for patients with true bacteremia, and the length of incubation time related to the recovery of probable true pathogens (short) versus contaminants (long). Finally, the microbiology and lab-centric humor sprinkled throughout the book makes reading enjoyable.\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003eAssessment\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003eThis is a fascinating book on the history and evolution of blood cultures. It is truly unique in its laser focus. For anyone interested in blood cultures and related technology, this is the book to read.\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003eReview Questionnaire\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003eRange\/ Question\/ Score\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003e1-10 Are the author's objectives met? 8\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003e1-10 Rate the worthiness of those objectives. 8\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003e1-5 Is this written at an appropriate level? 5\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003e1-5 Is there significant duplication? (1=significant, 5=insignificant) 4\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003e1-5 Are there significant omissions? (1=significant, 5=insignificant) 3\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003e1-5 Rate the authority of the authors. 5\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003e1-5 Are there sufficient illustrations? 3\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003e1-5 Rate the pedagogic value of the illustrations. 3\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003e1-5 Rate the print quality of the illustrations. 3\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003e1-5 Are there sufficient references? 5\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003e1-5 Rate the currency of the references. 4\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003e1-5 Rate the pertinence of the references. 4\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003e1-5 Rate the helpfulness of the index. 4\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003e1-5 If important in this specialty, rate the physical appearance of the book N\/A\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003e1-10 Is this a worthwhile contribution to the field? 6\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003e1-10 If this is a 2nd or later edition, is this new edition needed? N\/A\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan lang=\"EN-CA\"\u003e-Valerie Ng, PhD, MD,\u003c\/span\u003e\u003c\/b\u003e\u003cspan lang=\"EN-CA\"\u003e (Alameda County Medical Center\/Highland Hospital)\u003c\/span\u003e  \u003c\/p\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-CA\"\u003e \u003cp\u003e\u003cb\u003eWm. Michael Dunne, Jr.\u003c\/b\u003e, PhD, is currently a senior research fellow for bioMérieux, Inc. in Durham, North Carolina. Priorto joining bioMérieux, he was Medical Director of the Diagnostic Microbiology Laboratory at Barnes-Jewish Hospital and Professor of Pathology and Immunology, Molecular Microbiology, Pediatrics, and Medicine at Washington University School of Medicine in St. Louis from 2000-2011 and remainson the faculty there. During that time, he established an internationally-recognized training program in medical and public health microbiology, which is still active under the direction of Carey-Ann Burnham. He has previously served as Medical Director of Microbiology Laboratories at Henry Ford Hospital (Detroit, Michigan), Texas Children's Hospital (Baylor College of Medicine, Houston, Texas) and Children'sHospital of Wisconsin (Medical College of Wisconsin, Milwaukee, Wisconsin, where he had received his PhD in 1982). Dr. Dunne is a Diplomate of the American Board of Medical Microbiology and a Fellow of the American Academy of Microbiology, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Canadian College of Microbiology. He served as a senioreditor of the \u003ci\u003eJournal of Clinical Microbiology\u003c\/i\u003e for ten years and remains on the editorial board. He is also an Adjunct Professor of Pediatrics at Duke University School of Medicine, Durham, North Carolina. He has authored or coauthored over 170 peer-reviewed publications and 10 chapters, in addition to this book.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCarey-Ann D. Burnham\u003c\/b\u003e, PhD, completed her PhD in Medical Sciences at the University of Alberta in Edmonton, Alberta, Canada and her postdoctoral training in Medical and Public Health Microbiology at Washington University under the direction of Wm. Michael Dunne, Jr. Currently, Burnhamis an Associate Professor of Pathology \u0026amp; Immunology, Molecular Microbiology, and Pediatrics at Washington University in St. Louis School of Medicine. Burnham has a keen interestin education and is the Program Director for the Medical and Public Health Microbiology Fellowship at Washington University, the co-editor of Medical Microbiology Question of the Day, and the section editor of \u003ci\u003eThe Brief Case\u003c\/i\u003e for the \u003ci\u003eJournal of Clinical Microbiology\u003c\/i\u003e. Burnham's research program focuses on development of diagnostic assays for infectious diseases and the transmission and epidemiology of antimicrobial resistance in bacteria. Burnham has authored or coauthored more than 100 peer-reviewed publications in addition to numerous invited articles and book chapters.\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eThe Dark Art of Blood Cultures\u003c\/b\u003e \u003c\/p\u003e\n\u003cp\u003eFirst Edition \u003c\/p\u003e\n\u003cp\u003eIn the clinical microbiology laboratory, blood is a critical diagnostic sample that, in the majority of cases is sterile (or is it?). However, when microbes gain access to and multiply in the bloodstream, it can result in life-threatening illness including sepsis. Mortality rates from bloodstream infection and sepsis range from 25% to 80%, killing millions of people annually. Blood cultures are a vital technology used in the microbiology laboratory to isolate and identify microbes and predict their response to antimicrobial therapy. \u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eThe Dark Art of Blood Cultures\u003c\/i\u003e, edited by Wm. Michael Dunne, Jr., and Carey-Ann D. Burnham, surveys the entire field of blood culture technology, providing valuable information about every phase of the process, from drawing samples to culture methods to processing positive cultures. \u003ci\u003eThe Dark Art of Blood Cultures\u003c\/i\u003e is organized around several major topics. \u003c\/p\u003e\n\u003cul\u003e \u003cli\u003eHistory of blood culture methods. Details the timeline of blood culture methods from manual through automated and describes the technological development of the leading automated blood culture systems (Bactec, BacT\/Alert, and VersaTREK).\u003c\/li\u003e \u003cli\u003eManual and automated blood culture methods. Critiques manual and automated methods for setting up blood cultures for adult and pediatric patients.\u003c\/li\u003e  \u003cli\u003eDetection of pathogens directly from blood specimens. Describes currently available CE marked and FDA-cleared commercial tests using both phenotypic and genotypic markers, including their strengths and limitations.\u003c\/li\u003e \u003cli\u003eThe workflow of culturing blood. Includes best practices from specimen collection to culture system verification, processing positive cultures for microbe identification and antibiotic susceptibility determination, along with the epidemiology of positive blood cultures and the value of postmortem blood cultures.\u003c\/li\u003e \u003cli\u003eMicroorganisms in the blood. Examines the concept of a blood microbiome in healthy and diseased individuals.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eThe Dark Art of Blood Cultures\u003c\/i\u003e is a resource that clinicians, laboratorians, lab directors, and hospital administrators will find engaging and extremely useful.\u003c\/p\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"ASM Press","offers":[{"title":"Default Title","offer_id":47989022130405,"sku":"NP9781555819811","price":72.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781555819811.jpg?v=1761782473","url":"https:\/\/k12savings.com\/products\/dark-art-of-blood-cultures-isbn-9781555819811","provider":"K12savings","version":"1.0","type":"link"}