{"product_id":"cross-over-trials-in-clinical-research-isbn-9780471496533","title":"Cross-over Trials in Clinical Research","description":"Cross-over trials are an important class of design used in the pharmaceutical industry and medical research, and their use continues to grow. Cross-over Trials in Clinical Research, Second Edition has been fully updated to include the latest methodology used in the design and analysis of cross-over trials. It includes more background material, greater coverage of important statistical techniques, including Bayesian methods, and discussion of analysis using a number of statistical software packages.\u003cbr\u003e * Comprehensive coverage of the design and analysis of cross-over trials.\u003cbr\u003e \u003cbr\u003e * Each technique is carefully explained and the mathematics is kept to a minimum.\u003cbr\u003e \u003cbr\u003e * Features many real and original examples, taken from the author's vast experience.\u003cbr\u003e \u003cbr\u003e * Includes discussion of analysis using SAS, S-Plus and, GenStat, StatXact and Excel.\u003cbr\u003e \u003cbr\u003e * Written in a style suitable for statisticians and physicians alike.\u003cbr\u003e Primarily aimed at statisticians and researchers working in the pharmaceutical industry, the book will also appeal to physicians involved in clinical research and students of medical statistics. Preface to the Second Edition.\u003cbr\u003e \u003cbr\u003e Preface to the First Edition.\u003cbr\u003e \u003cbr\u003e 1. Introduction.\u003cbr\u003e \u003cbr\u003e 2. Some Basic Considerations Concerning Estimation in Clinical Trials.\u003cbr\u003e \u003cbr\u003e 3. The AB\/BA Design with Normal Data.\u003cbr\u003e \u003cbr\u003e 4. Other Outcomes and the AB\/BA Design.\u003cbr\u003e \u003cbr\u003e 5. Normal Data from Designs with Three or More Treatments.\u003cbr\u003e \u003cbr\u003e 6. Other Outcomes from Designs with Three or More Treatments.\u003cbr\u003e \u003cbr\u003e 7. Some Special Designs.\u003cbr\u003e \u003cbr\u003e 8. Graphical and Tabular Presentation of Cross-over Trials.\u003cbr\u003e \u003cbr\u003e 9. Various Design Issues.\u003cbr\u003e \u003cbr\u003e 10. Mathematical Approaches to Carry-over.\u003cbr\u003e \u003cbr\u003e References.\u003cbr\u003e \u003cbr\u003e Author Index.\u003cbr\u003e \u003cbr\u003e Subject Index.  \"…clearly written…mode of presentation is very effective…I recommend this book as a useful resource…\" (\u003ci\u003eJournal of the American Statistical Association\u003c\/i\u003e, December 2004)  \u003cp\u003e\"The book by Senn was the very first volume in Wiley's excellent series, \"Statistics in Practice\".  Here, 10 years later, it is now the first of the books in that series to reappear in a second addition.” (\u003ci\u003eTechnometrics\u003c\/i\u003e, May 2004)\u003c\/p\u003e \u003cp\u003e\"...well structured and easy to read...incredibly useful...\" (\u003ci\u003eApplied Clinical Trials\u003c\/i\u003e, December 2002)\u003c\/p\u003e \u003cp\u003e\"...an excellent reference source and is easily readable.\" (\u003ci\u003eThe Statistician\u003c\/i\u003e)\u003c\/p\u003e \u003cp\u003e\"...explanation are kept as non-technical as possible, although they do not lack statistical rigour...well worth reading...\" (\u003ci\u003ePharmaceutical Statistics\u003c\/i\u003e, Vol 2, 2003)\u003c\/p\u003e \u003cp\u003e“…the main additions can be seen as …adding to the arguments for the author’s view on carryover affects...” (Clinical Trials, No.1 2004) \u003c\/p\u003e \u003cb\u003eStephen Senn\u003c\/b\u003e has worked for the NHS in England, as a lecturer in Scotland and in drug development in Switzerland (with CIBA-Geigy). Until recently he was Professor of Pharmaceutical and Health Statistics at University College London but since September 2003 he has been  Professor of Statistics at Glasgow University. His books, \u003ci\u003eCross-over Trials in Clinical Research\u003c\/i\u003e (1993, 2\u003csup\u003end\u003c\/sup\u003e edition 2002) and \u003ci\u003eStatistical Issues in Drug Development\u003c\/i\u003e (1997) are published by Wiley and his latest book, \u003ci\u003eDicing with Death\u003c\/i\u003e (2003) by Cambridge University Press. In 2001, he was the first recipient of the George C Challis award for biostatistics of the University of Florida. He is a member of the editorial boards of \u003ci\u003eStatistics in Medicine\u003c\/i\u003e, \u003ci\u003eStatistical Methods in Medical Research\u003c\/i\u003e, \u003ci\u003ePharmaceutical Statistics\u003c\/i\u003e and \u003ci\u003eApplied Clinical Trials\u003c\/i\u003e and is a section editor for the Wiley \u003ci\u003eStatistics in Practice\u003c\/i\u003e series. \u003cp\u003eCross-over trials are an important class of design used in the pharmaceutical industry and medical research, and their use continues to grow. \u003ci\u003eCross-over Trials in Clinical Research\u003c\/i\u003e, Second Edition has been fully updated to include the latest methodology used in the design and analysis of cross-over trials. It includes more background material, greater coverage of important statistical techniques, including Bayesian methods, and discussion of analysis using a number of statistical software packages.\u003c\/p\u003e \u003cul\u003e \u003cli\u003eComprehensive coverage of the design and analysis of cross-over trials.\u003c\/li\u003e \u003cli\u003eEach technique is carefully explained and the mathematics is kept to a minimum.\u003c\/li\u003e \u003cli\u003eFeatures many real and original examples, taken from the author's vast experience.\u003c\/li\u003e \u003cli\u003eIncludes discussion of analysis using SAS, S-Plus and, GenStat, StatXact and Excel.\u003c\/li\u003e \u003cli\u003eWritten in a style suitable for statisticians and physicians alike.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003ePrimarily aimed at statisticians and researchers working in the pharmaceutical industry, the book will also appeal to physicians involved in clinical research and students of medical statistics.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47989008826597,"sku":"NP9780471496533","price":169.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780471496533.jpg?v=1761782414","url":"https:\/\/k12savings.com\/products\/cross-over-trials-in-clinical-research-isbn-9780471496533","provider":"K12savings","version":"1.0","type":"link"}