{"product_id":"chiral-separation-methods-for-pharmaceutical-and-biotechnological-products-isbn-9780470406915","title":"Chiral Separation Methods for Pharmaceutical and Biotechnological Products","description":"\u003cb\u003eDiscusses chiral separations and offers guidance for selecting the optimum method for desired results\u003c\/b\u003e  \u003cp\u003eChiral separations represent the most intriguing and, by some measures, most difficultseparations of chemical compounds. This book provides researchers and students an under-standing of chiral separations and offers a convenient route to selecting the best separation method, saving considerable time and cost in product development.\u003c\/p\u003e \u003cp\u003eConsidering chiral separations in the biotechnological and pharmaceutical industries, as well as for food applications, Dr. Ahuja provides insights into a broad range of topics. Opening with a broad overview of chiral separations, regulatory considerations in drug product development, and basic issues in method development, the book:\u003c\/p\u003e \u003cul\u003e \u003cli\u003e \u003cp\u003eCovers a variety of modern methods such as gas chromatography, high performance liquid chromatography, supercritical fluid chromatography, and capillary electrophoresis\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eDeals with the impact of chirality on the biological activity of small and large molecules\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eProvides detailed information on useful chiral stationary phases (CSPs) for HPLC\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eIncludes handy information on selection of an appropriate CSP, including mechanistic studies\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eOffers strategies for fast method development with HPLC, SFC, and CE\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eDiscusses preparatory methods utilized in the pharmaceutical industry\u003c\/p\u003e \u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eWith in-depth discussions of the current state of the field as well as suggestions to assist future developments, \u003ci\u003eChiral Separation Methods for Pharmaceutical and Biotechnological Products\u003c\/i\u003e is an essential text for laboratory investigators, managers, and regulators who are involved in chiral separations in the pharmaceutical industry, as well as students preparing for careers in these fields.\u003c\/p\u003e  Contributors.  \u003cp\u003ePreface.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Overview of Chiral Separations\u003c\/b\u003e (\u003ci\u003eSatinder Ahuja\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Regulatory \u0026amp; Development Considerations of Chiral Compounds\u003c\/b\u003e (\u003ci\u003eRobert L. Zeid\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Basic Considerations in Method Development for Chiral Compounds\u003c\/b\u003e (\u003ci\u003eSatinder Ahuja\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Separations of Chiral Compounds on Polysaccharide Columns\u003c\/b\u003e (\u003ci\u003eClinton W. Amoss and Norbert M. Maier\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Chiral Separations by Various Techniques\u003c\/b\u003e (\u003ci\u003eJian G. Ning\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Chiral Discrimination Study for Polysaccharide Based Chiral Stationary Phase\u003c\/b\u003e (\u003ci\u003eYun K. Ye\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Comparison of Chiral Chromatographic Columns for Pharmaceuticals\u003c\/b\u003e (\u003ci\u003eGregory K. Webster\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Chiral Separation Screens for Pharmaceutical Analysis and Purification in an Industrial Laboratory Environment\u003c\/b\u003e (\u003ci\u003eRobert DePianta, Kenneth Douville, Beverly Nickerson, and Ricardo E. Borjas\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 The Separation of Enantiomers by Gas Chromatography on Chiral Stationary Phases\u003c\/b\u003e (\u003ci\u003eVolker Schurig\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Separations of Chiral Compounds by SFC\u003c\/b\u003e (\u003ci\u003eZiqiang Wang\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Chiral Separations by Capillary Electrophoresis\u003c\/b\u003e (\u003ci\u003eDebby Mangelings and Yvan Vander Heyden\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 High-Throughput Screening and Method-Development Strategies to Separate Chiral Drug Compounds in HPLC, SFC, and CE\u003c\/b\u003e (\u003ci\u003eHasret Ates, Debby Mangelings and Yvan Vander Heyden\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Use of Enantioselective Synthesis and Preparative Chiral Chromatography to Access a Challenging Enantiopure Pharmaceutical Candidate from a Mixture of Four Stereoisomers\u003c\/b\u003e (\u003ci\u003eChristopher J. Welch, Derek H. Henderson, William R. Leonard, Mirlinda Biba, Mike Zacuto, Fred Fleitz, Amude Kassim, Cheng-yi Chen, and Peter Sajonz\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 A Look into the Future: Chiral Analysis Using Chemical Sensor Technology\u003c\/b\u003e (\u003ci\u003eGregory K. Webster and William J. Buttner\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Chirality of Biomolecules and Biotechnology Products\u003c\/b\u003e (\u003ci\u003eSatinder Ahuja\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eIndex.\u003c\/p\u003e  \u003cp\u003e“All chapters are thorough and well written by leading experts in the particular fields. The book provides researchers and students in the field of pharmaceutical sciences with a thorough understanding of chiral separations and offers a convenient route to selecting best chiral separation method.”  (\u003ci\u003eAnal Bioanal Chem\u003c\/i\u003e, 2011)\u003c\/p\u003e \u003cp\u003e\"This is an essential text for analytical and separations scientists in the biotechnological, pharmaceutical, agricultural, and food industries, as well as students.\" (Laboratory Journal, 22 November 2010)\u003c\/p\u003e \u003cb\u003eSATINDER (SUT) AHUJA\u003c\/b\u003e is a recognized expert in the field of chromatography and separations who has published numerous papers and more than a dozen books, including three on chiral separations. As president of Ahuja Consulting, he has advised major pharmaceutical companies in the United States, Europe, and India. He has also taught short courses for ACS and AAPS on chiral separations by chromatography. Recently, Dr. Ahuja chaired a symposium on Chiral Separations at the American Chemical Society meeting in Boston.  \u003cb\u003eDiscusses chiral separations and offers guidance for selecting the optimum method for desired results\u003c\/b\u003e  \u003cp\u003eChiral separations represent the most intriguing and, by some measures, most difficultseparations of chemical compounds. This book provides researchers and students an under-standing of chiral separations and offers a convenient route to selecting the best separation method, saving considerable time and cost in product development.\u003c\/p\u003e \u003cp\u003eConsidering chiral separations in the biotechnological and pharmaceutical industries, as well as for food applications, Dr. Ahuja provides insights into a broad range of topics. Opening with a broad overview of chiral separations, regulatory considerations in drug product development, and basic issues in method development, the book:\u003c\/p\u003e \u003cul\u003e \u003cli\u003e \u003cp\u003eCovers a variety of modern methods such as gas chromatography, high performance liquid chromatography, supercritical fluid chromatography, and capillary electrophoresis\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eDeals with the impact of chirality on the biological activity of small and large molecules\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eProvides detailed information on useful chiral stationary phases (CSPs) for HPLC\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eIncludes handy information on selection of an appropriate CSP, including mechanistic studies\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eOffers strategies for fast method development with HPLC, SFC, and CE\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eDiscusses preparatory methods utilized in the pharmaceutical industry\u003c\/p\u003e \u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eWith in-depth discussions of the current state of the field as well as suggestions to assist future developments, \u003ci\u003eChiral Separation Methods for Pharmaceutical and Biotechnological Products\u003c\/i\u003e is an essential text for laboratory investigators, managers, and regulators who are involved in chiral separations in the pharmaceutical industry, as well as students preparing for careers in these fields.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47988917534949,"sku":"NP9780470406915","price":176.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470406915.jpg?v=1761782043","url":"https:\/\/k12savings.com\/products\/chiral-separation-methods-for-pharmaceutical-and-biotechnological-products-isbn-9780470406915","provider":"K12savings","version":"1.0","type":"link"}