{"product_id":"an-introduction-to-forensic-genetics-isbn-9780470710197","title":"An Introduction to Forensic Genetics","description":"This is a completely revised edition of a comprehensive and popular introduction to the fast moving area of Forensic Genetics. The text begins with key concepts needed to fully appreciate the subject and moves on to examine the latest developments in the field. Now illustrated in full colour throughout, this accessible textbook includes numerous references to relevant casework. With information on the full process of DNA evidence from collection at the scene of a crime to presentation in a legal context this book provides a complete overview of the field.  \u003cp\u003e \u003cb\u003eKey Features:\u003c\/b\u003e\u003c\/p\u003e \u003cul\u003e \u003cli\u003eGreater in-depth coverage of kinship problems now covered in two separate chapters: one dealing with relationships between living individuals and the other covering identification of human remains. \u003c\/li\u003e \u003cli\u003eNew chapter on non-human forensic genetics, including identification of bacteria and viruses, animals and plants. \u003c\/li\u003e \u003cli\u003eSelf assessment questions to aid student understanding throughout the text. \u003c\/li\u003e \u003cli\u003eNow with full colour illustrations throughout \u003c\/li\u003e \u003cli\u003eNew companion website \u003c\/li\u003e \u003cli\u003eAccessible introduction to forensic genetics, from the collection of evidence to the presentation of evidence in a legal context. \u003c\/li\u003e \u003c\/ul\u003e  \u003cp\u003e Included in the Forensic Science Society 'Essentials in Forensic Science' book series. This edition is to be included in the Forensic Science Society 'Essentials of Forensic Science' book series aimed at advanced level undergraduates and new practitioners to the field.\u003c\/p\u003e \u003cp\u003eForeword ix\u003c\/p\u003e \u003cp\u003ePreface xi\u003c\/p\u003e \u003cp\u003ePreface to first edition xiii\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Introduction to forensic genetics 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eForensic genetics 1\u003c\/p\u003e \u003cp\u003eA brief history of forensic genetics 2\u003c\/p\u003e \u003cp\u003eReferences 6\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 DNA structure and the genome 11\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eDNA structure 11\u003c\/p\u003e \u003cp\u003eOrganization of DNA into chromosomes 11\u003c\/p\u003e \u003cp\u003eThe structure of the human genome 13\u003c\/p\u003e \u003cp\u003eGenetic diversity of modern humans 15\u003c\/p\u003e \u003cp\u003eThe genome and forensic genetics 16\u003c\/p\u003e \u003cp\u003eTandem repeats 16\u003c\/p\u003e \u003cp\u003eSingle nucleotide polymorphisms 18\u003c\/p\u003e \u003cp\u003eReferences 19\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Biological material – collection, characterization and storage 21\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eSources of biological evidence 21\u003c\/p\u003e \u003cp\u003eCollection and handling of material at the crime scene 23\u003c\/p\u003e \u003cp\u003eIdentification and characterization of biological evidence 23\u003c\/p\u003e \u003cp\u003eEvidence collection 29\u003c\/p\u003e \u003cp\u003eSexual and physical assault 31\u003c\/p\u003e \u003cp\u003eStorage of biological material 32\u003c\/p\u003e \u003cp\u003eReferences 32\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 DNA extraction and quantification 37\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eDNA extraction 37\u003c\/p\u003e \u003cp\u003eGeneral principles of DNA extraction 37\u003c\/p\u003e \u003cp\u003eDNA extraction from challenging samples 41\u003c\/p\u003e \u003cp\u003eQuantification of DNA 45\u003c\/p\u003e \u003cp\u003eDNA IQ system 48\u003c\/p\u003e \u003cp\u003eReferences 49\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Polymerase chain reaction 53\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eThe evolution of PCR-based profiling in forensic genetics 53\u003c\/p\u003e \u003cp\u003eDNA replication: the basis of the PCR 54\u003c\/p\u003e \u003cp\u003eThe components of PCR 54\u003c\/p\u003e \u003cp\u003eTaq DNA polymerase 54\u003c\/p\u003e \u003cp\u003eThe PCR process 56\u003c\/p\u003e \u003cp\u003ePCR inhibition 58\u003c\/p\u003e \u003cp\u003eSensitivity and contamination 60\u003c\/p\u003e \u003cp\u003eThe PCR laboratory 60\u003c\/p\u003e \u003cp\u003eFurther reading 62\u003c\/p\u003e \u003cp\u003eReferences 62\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 The analysis of short tandem repeats 67\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eStructure of STR loci 67\u003c\/p\u003e \u003cp\u003eThe development of STR multiplexes 67\u003c\/p\u003e \u003cp\u003eDetection of STR polymorphisms 70\u003c\/p\u003e \u003cp\u003eInterpretation of STR profiles 72\u003c\/p\u003e \u003cp\u003eFurther reading 77\u003c\/p\u003e \u003cp\u003eReferences 77\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Assessment of STR profiles 81\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eStutter peaks 81\u003c\/p\u003e \u003cp\u003eSplit peaks (±\u003ci\u003eN\u003c\/i\u003e) 81\u003c\/p\u003e \u003cp\u003ePull-up 83\u003c\/p\u003e \u003cp\u003eTemplate DNA 84\u003c\/p\u003e \u003cp\u003eOverloaded profiles 84\u003c\/p\u003e \u003cp\u003eLow template DNA typing 84\u003c\/p\u003e \u003cp\u003ePeak balance 86\u003c\/p\u003e \u003cp\u003eMixtures 86\u003c\/p\u003e \u003cp\u003eDegraded DNA 88\u003c\/p\u003e \u003cp\u003ePCR inhibition 90\u003c\/p\u003e \u003cp\u003eReferences 91\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Statistical interpretation of STR profiles 95\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003ePopulation genetics 95\u003c\/p\u003e \u003cp\u003eDeviation from the Hardy–Weinberg equilibrium 96\u003c\/p\u003e \u003cp\u003eStatistical tests to determine deviation from the Hardy–Weinberg equilibrium 97\u003c\/p\u003e \u003cp\u003eEstimating the frequencies of STR profiles 98\u003c\/p\u003e \u003cp\u003eCorrections to allele frequency databases 98\u003c\/p\u003e \u003cp\u003eWhich population frequency database should be used? 103\u003c\/p\u003e \u003cp\u003eConclusions 104\u003c\/p\u003e \u003cp\u003eFurther reading 104\u003c\/p\u003e \u003cp\u003eReferences 104\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Evaluation and presentation of DNA evidence 107\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eHierarchies of propositions 107\u003c\/p\u003e \u003cp\u003eLikelihood ratios 109\u003c\/p\u003e \u003cp\u003eTwo fallacies 113\u003c\/p\u003e \u003cp\u003eComparison of three approaches 114\u003c\/p\u003e \u003cp\u003eFurther reading 115\u003c\/p\u003e \u003cp\u003eReferences 115\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Databases of DNA profiles 117\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eThe UK National DNA Database 117\u003c\/p\u003e \u003cp\u003eInternational situation 124\u003c\/p\u003e \u003cp\u003eFurther reading 128\u003c\/p\u003e \u003cp\u003eReferences 128\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Kinship testing 131\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eParentage testing 131\u003c\/p\u003e \u003cp\u003ePunnett square 132\u003c\/p\u003e \u003cp\u003eIdentification of human remains 139\u003c\/p\u003e \u003cp\u003eFurther reading 140\u003c\/p\u003e \u003cp\u003eReferences 140\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Single nucleotide polymorphisms 145\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eSNPs – occurrence and structure 145\u003c\/p\u003e \u003cp\u003eDetection of SNPs 146\u003c\/p\u003e \u003cp\u003eSNP detection for forensic applications 148\u003c\/p\u003e \u003cp\u003eForensic applications of SNPs 149\u003c\/p\u003e \u003cp\u003eSNPs compared with STR loci 150\u003c\/p\u003e \u003cp\u003eReferences 152\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Lineage markers 155\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eMitochondria 155\u003c\/p\u003e \u003cp\u003eApplications of mtDNA profiling 157\u003c\/p\u003e \u003cp\u003eHaplotypes and haplogroups 159\u003c\/p\u003e \u003cp\u003eThe Y chromosome 161\u003c\/p\u003e \u003cp\u003eForensic applications of Y chromosome polymorphisms 162\u003c\/p\u003e \u003cp\u003eFurther reading 165\u003c\/p\u003e \u003cp\u003eReferences 165\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Non-human DNA typing 171\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eNon-human sample types 171\u003c\/p\u003e \u003cp\u003eSpecies identification 173\u003c\/p\u003e \u003cp\u003eLinkage to an individual using STR loci 174\u003c\/p\u003e \u003cp\u003eLinkage to an individual using mitochondrial loci 175\u003c\/p\u003e \u003cp\u003eMicrobial DNA testing 176\u003c\/p\u003e \u003cp\u003eConcluding comments 176\u003c\/p\u003e \u003cp\u003eFurther reading 176\u003c\/p\u003e \u003cp\u003eReferences 176\u003c\/p\u003e \u003cp\u003eAppendix A Forensic parameters 181\u003c\/p\u003e \u003cp\u003eAppendix B Useful web links 183\u003c\/p\u003e \u003cp\u003eGlossary 185\u003c\/p\u003e \u003cp\u003eAbbreviations 189\u003c\/p\u003e \u003cp\u003eIndex 193\u003c\/p\u003e \u003cp\u003e\u003cb\u003eDr Will Goodwin\u003c\/b\u003e, Senior Lecturer in Forensic Genetics, Faculty of Science and Technology, University of Central Lancashire.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eDr Sibte Hadi\u003c\/b\u003e, Senior Lecturer in Forensic Genetics, Faculty of Science and Technology, University of Central Lancashire.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eDr Adrian M. T. Linacre\u003c\/b\u003e, Department of Pure and Applied Chemistry, University of Strathclyde.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eAn Introduction to Forensic Genetics, Second Edition\u003c\/i\u003e is a revised edition of this comprehensive and popular introduction to the fast moving area of Forensic Genetics. The book begins with the key concepts needed to fully appreciate the subject and moves on to examine the latest developments in the field. Now illustrated in full colour throughout, this accessible textbook includes references to relevant casework. With information on the full process of DNA evidence from collection at the scene of a crime to presentation in a legal context, providing a complete overview of the field.\u003c\/p\u003e \u003cp\u003eA new chapter looking at non-human forensic genetics, including identification of bacteria and viruses, animals and plants is also included.\u003c\/p\u003e \u003cul\u003e \u003cli\u003eNow with full colour illustrations throughout\u003c\/li\u003e \u003cli\u003eNew companion wesites at www.wiley.com\/go\/forensic2e\u003c\/li\u003e \u003cli\u003eGreater coverage of kinship problems\u003c\/li\u003e \u003cli\u003eAccessible introduction to forensic genetics, from the collection of evidence to the presentation of evidence in a legal context\u003c\/li\u003e \u003c\/ul\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47988726169829,"sku":"NP9780470710197","price":69.5,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780470710197.jpg?v=1761781345","url":"https:\/\/k12savings.com\/products\/an-introduction-to-forensic-genetics-isbn-9780470710197","provider":"K12savings","version":"1.0","type":"link"}