{"product_id":"advances-in-drug-discovery-techniques-isbn-9780471975090","title":"Advances in Drug Discovery Techniques","description":"This invaluable volume serves as a guide to up-to-the-minute techniques for the discovery and evaluation of pharmacologically active compounds for therapeutic development. Focusing on practical applications, provided by expert practitioners from both industry and academic research laboratories, Advances in Drug Discovery Techniques covers rational drug design, high-throughput screening and genetic approaches to drug discovery. Moreover, chapters also focus on advances in the use of combinatorial chemistry and natural products, both of which support the chemical diversity for many drug screening programmes. Typical screening studies and their link to robotics and informatics are also presented in detail, together with an overview of current progress within antisense therapeutics. Overall, this book will be an excellent reference source for all individuals interested in making sense of the rapid changes in drug discovery that result from developments in molecular biology, robotics and informatics.Pharmazieunternehmen verwenden zwar immer mehr Mittel, Zeit und Personal auf Forschung und Entwicklung, jedoch sinkt die Zahl der jährlich neu zugelassenen Medikamente weiter ab. Dieses Buch zeigt Wege auf, die zu neuen Wirkstoffgruppen führen können, wobei die Betonung hier eher auf einem breiten Überblick, als auf einer detaillierten Besprechung einzelner Methoden liegt. Ausführlich analysiert werden die Veränderungen, die sich gegenwärtig in der pharmazeutischen Forschung und Entwicklung manifestieren. (06\/98) Sense, Nonsense and Antisense: Different Approaches to Drug Discovery (A. Harvey).\u003cbr\u003e \u003cbr\u003e Natural Products for Durg Discovery: An Overview (P. Waterman).\u003cbr\u003e \u003cbr\u003e Advanced Screening Technology and Informatics for Natural Products Drug Discovery (D. Hill).\u003cbr\u003e \u003cbr\u003e Discovery of Specific Tyrosine Kinase Inhibitors from Microbial and Botanical Sources (G. McMahon, et al.).\u003cbr\u003e \u003cbr\u003e Plant Cell Culture: A Vehicle for Drug Discovery (A. Stafford, et al.).\u003cbr\u003e \u003cbr\u003e Pharmacy of the Deep -\u003cbr\u003e Marine Organisms as Sources of Anticancer Agents (M. Jaspars).\u003cbr\u003e \u003cbr\u003e Drug Discovery by Using Molecular Biology to Reprogramme Microorganisms (I. Hunter).\u003cbr\u003e \u003cbr\u003e Small Molecule Drug Screening Based on Surface Plasmon Resonance (S. Kumar \u0026amp; K. Gunnarsson).\u003cbr\u003e \u003cbr\u003e An Overview of Combinatorial Chemistry and Its Applications to the Identification of Matric Metalloproteinase Inhibitors (MMPIs) (S. Shuttleworth).\u003cbr\u003e \u003cbr\u003e New Methods for Structure-based De Novo Drug Design (B. Waszkowycz).\u003cbr\u003e \u003cbr\u003e Current and Future Capabilities in Automated Drug Screening and Development (I. Norrington).\u003cbr\u003e \u003cbr\u003e Antisense Oligonucleotide Therapeutics (C. Bennett, et al.).\u003cbr\u003e \u003cbr\u003e Index.  \u003cp\u003eAlan L. Harvey is the author of Advances in Drug Discovery Techniques, published by Wiley.  This invaluable volume serves as a guide to up-to-the-minute techniques for the discovery and evaluation of pharmacologically active compounds for therapeutic development. Focusing on practical applications, provided by expert practitioners from both industry and academic research laboratories, Advances in Drug Discovery Techniques covers rational drug design, high-throughput screening and genetic approaches to drug discovery. Moreover, chapters also focus on advances in the use of combinatorial chemistry and natural products, both of which support the chemical diversity for many drug screening programmes. Typical screening studies and their link to robotics and informatics are also presented in detail, together with an overview of current progress within antisense therapeutics. Overall, this book will be an excellent reference source for all individuals interested in making sense of the rapid changes in drug discovery that result from developments in molecular biology, robotics and informatics.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47988677574885,"sku":"NP9780471975090","price":298.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780471975090.jpg?v=1761781220","url":"https:\/\/k12savings.com\/products\/advances-in-drug-discovery-techniques-isbn-9780471975090","provider":"K12savings","version":"1.0","type":"link"}