Addiction Reviews 3, Volume 1216

Addiction Reviews 3 features refereed reviews of topics of interest to specialists in addiction. Contributions that NIAAA and investigators interested in alcoholism have made to the field of addiction is the focus of this volume. Among the specific issues covered are: alcoholic liver disease exacerbated by malnutrition or infections; hippocampus, amygdala and stressand susceptibility to addiction; alcohol binge drinking; epigenetics of addiction; and the pharmacological enhancement of drug cue extinction learning.

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Evaluation of reward from pain relief 1
Edita Navratilova, Jennifer Yanhua Xie, Tamara King and Frank Porreca

Associative learning mechanisms underpinning the transition from recreational drug use to addiction 12
Lee Hogarth, Bernard W. Balleine, Laura H. Corbit and Simon Killcross

Lipids and addiction: how sex steroids, prostaglandins, and cannabinoids interact with drugs of abuse 25
Emma Leishman, Kevin J. Kokesh and Heather B. Bradshaw

The genetics of alcohol dependence 39
Marcella Rietschel and Jens Treutlein

Substance use disorders: a theory-driven approach to the integration of genetics and neuroimaging 71
Hollis C. Karoly, Nicole Harlaar and Kent E. Hutchinson

Analytical strategies for large imaging genetic datasets: experiences from the IMAGEN study 92
Charlotte Nymberg, Tianye Jia, Barbara Ruggeri and Gunter Schumann

Addiction and corticotropin-releasing hormone type 1 receptor antagonist medications 107
Carlo Contoreggi, Mary R. Lee and George Chrousos

Deep brain stimulation of the nucleus accumbens for the treatment of addiction 119
Ulf J. Müller, Jürgen Voges, Johann Steiner, Imke Galazky, Hans-Jochen Heinze, Michaela Möller, Jared Pisapia, Casey Halpern, Arthur Caplan, Bernhard Bogerts and Jens Kuhn

George R. Uhl, M.D., Ph.D, is with the National Institutes of Health, Molecular Neurobiology Research Branch, in Baltimore, Maryland. His expertise covers Genetics, Neuroscience and Molecular Biology.