{"product_id":"uremic-toxins-isbn-9781118135136","title":"Uremic Toxins","description":"\u003cp\u003e\u003cb\u003eReviews all the latest basic and clinical research findings\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eWith contributions from leading international experts in the field, this book is dedicated to all facets of uremic toxins research, including low molecular weight solutes, protein-bound solutes, and middle molecules. Moreover, it covers everything from basic mass spectrometry research to the latest clinical findings and practices.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eUremic Toxins\u003c\/i\u003e is divided into three sections:\u003c\/p\u003e \u003cul\u003e \u003cli\u003e\n\u003cb\u003eSection One,\u003c\/b\u003e Uremic Toxins, explores the definition, classification, listing, and mass spectrometric analysis of uremic toxins\u003c\/li\u003e \u003cli\u003e\n\u003cb\u003eSection Two,\u003c\/b\u003e Selected Uremic Toxins, describes key uremic toxins, explaining chemical structures, metabolism, analytical methods, plasma levels, toxicity, clinical implications, and removal methods. Among the uremic toxins covered are indoxyl sulfate, asymmetric dimethylarginine, PTH, ß2-microglobulin, and AGEs\u003c\/li\u003e \u003cli\u003e\n\u003cb\u003eSection Three,\u003c\/b\u003e Therapeutic Removal of Uremic Toxins, describes how uremic toxins can be removed by hemodialysis, peritoneal dialysis, and oral sorbent\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eAll chapters are based on the authors' thorough review of the literature as well as their own personal laboratory and clinical experience. References at the end of each chapter provide a gateway to the literature in the field.\u003c\/p\u003e \u003cp\u003eReviewing all the latest basic and clinical research findings, \u003ci\u003eUremic Toxins\u003c\/i\u003e will help bench scientists in nephrology advance their own investigations. It will also help clinicians take advantage of the latest tested and proven treatments for the management of chronic kidney disease.\u003c\/p\u003e  \u003cp\u003ePREFACE ix\u003c\/p\u003e \u003cp\u003eCONTRIBUTORS xi\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSECTION 1: UREMIC TOXINS 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1. Uremic Toxins: An Integrated Overview of Definition and Classification 3\u003cbr\u003e \u003ci\u003eRichard J. Glassock and Shaul G. Massry\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2. Classification and a List of Uremic Toxins 13\u003cbr\u003e \u003ci\u003eNathalie Neirynck, Rita De Smet, Eva Schepers, Raymond Vanholder, and Griet Glorieux\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3. Analysis of Uremic Toxins with Mass Spectrometry 35\u003cbr\u003e \u003ci\u003eToshimitsu Niwa\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSECTION 2: SELECTED UREMIC TOXINS 51\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4. Indoxyl Sulfate 53\u003cbr\u003e \u003ci\u003eToshimitsu Niwa\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5. p-Cresyl Sulfate 77\u003cbr\u003e \u003ci\u003eAnneleen Pletinck, Raymond Vanholder, and Griet Glorieux\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6. 3-Carboxy-4-methyl-5-propyl-2-furanpropionic Acid 87\u003cbr\u003e \u003ci\u003eToshimitsu Niwa\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7. Phenylacetic Acid 99\u003cbr\u003e \u003ci\u003eAnna Schulz and Joachim Jankowski\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8. Homocysteine and Hydrogen Sulfide, Two Opposing Aspects in the Pathobiology of Sulfur Compounds in Chronic Renal Failure 109\u003cbr\u003e \u003ci\u003eAlessandra F. Perna and Diego Ingrosso\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9. Guanidino Compounds 125\u003cbr\u003e \u003ci\u003eSunny Eloot, Griet Glorieux, Peter Paul De Deyn, and Raymond Vanholder\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10. Asymmetric Dimethylarginine 143\u003cbr\u003e \u003ci\u003eVladimýr Teplan and Jaroslav Racek\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11. Nicotinamide Metabolites 163\u003cbr\u003e \u003ci\u003eBoleslaw Rutkowski and Przemyslaw Rutkowski\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12. Dicarbonyls (Glyoxal, Methylglyoxal, and 3-Deoxyglucosone) 177\u003cbr\u003e \u003ci\u003eNaila Rabbani and Paul J. Thornalley\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13. Glucose Degradation Products in Peritoneal Dialysis 193\u003cbr\u003e \u003ci\u003eMonika Pischetsrieder and Sabrina Gensberger\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14. Dinucleoside Polyphosphates 209\u003cbr\u003e \u003ci\u003eJoachim Jankowski and Vera Jankowski\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15. Parathyroid Hormone 227\u003cbr\u003e \u003ci\u003eShaul G. Massry and Miroslaw Smogorzewski\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16. b2-Microglobulin 249\u003cbr\u003e \u003ci\u003eSuguru Yamamoto, Junichiro James Kazama, Hiroki Maruyama, Ichiei Narita, and Fumitake Gejyo\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17. Cytokines 259\u003cbr\u003e \u003ci\u003eBj€orn Anderstam, Bengt Lindholm, and Peter Stenvinkel\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18. Free Immunoglobulin Light Chains 279\u003cbr\u003e \u003ci\u003eGerald Cohen and Walter H. H€orl\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e19. Advanced Glycation Endproducts (AGEs) 293\u003cbr\u003e \u003ci\u003eNaila Rabbani and Paul J. Thornalley\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e20. Oxidized Albumin 305\u003cbr\u003e \u003ci\u003eMaurizio Bruschi, Giovanni Candiano, Laura Santucci, and Gian Marco Ghiggeri\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSECTION 3: THERAPEUTIC REMOVAL OF UREMIC TOXINS 315\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e21. Therapeutic Removal of Uremic Toxins by Hemodialysis 317\u003cbr\u003e \u003ci\u003eTammy L. Sirich, Pavel Aronov, and Timothy W. Meyer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e22. Therapeutic Removal of Uremic Toxins by Peritoneal Dialysis 331\u003cbr\u003e Malgorzata Debowska, Elvia Garcýa-Lopez, Jacek Waniewski, and Bengt Lindholm\u003c\/p\u003e \u003cp\u003e23. Therapeutic Removal of Uremic Toxins by Oral Sorbent 359\u003cbr\u003e \u003ci\u003eToshimitsu Niwa\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eINDEX 373\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eTOSHIMITSU NIWA, MD, PhD,\u003c\/b\u003e is Professor in the Department of Advanced Medicine for Uremia at the Nagoya University Graduate School of Medicine. President of the Japanese Society for Biomedical Mass Spectrometry, Dr. Niwa has received many honors for his research, including the Kimoto Prize of the Japanese Society for Dialysis Therapy and the International Society of Uremia Research and Toxicity Award. He has published more than 300 articles in peer-reviewed journals.\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eReviews all the latest basic and clinical research findings\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eWith contributions from leading international experts in the field, this book is dedicated to all facets of uremic toxins research, including low molecular weight solutes, protein-bound solutes, and middle molecules. Moreover, it covers everything from basic mass spectrometry research to the latest clinical findings and practices.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eUremic Toxins\u003c\/i\u003e is divided into three sections:\u003c\/p\u003e \u003cul\u003e \u003cli\u003e\n\u003cb\u003eSection One,\u003c\/b\u003e Uremic Toxins, explores the definition, classification, listing, and mass spectrometric analysis of uremic toxins\u003c\/li\u003e \u003cli\u003e\n\u003cb\u003eSection Two,\u003c\/b\u003e Selected Uremic Toxins, describes key uremic toxins, explaining chemical structures, metabolism, analytical methods, plasma levels, toxicity, clinical implications, and removal methods. Among the uremic toxins covered are indoxyl sulfate, asymmetric dimethylarginine, PTH, ß2-microglobulin, and AGEs\u003c\/li\u003e \u003cli\u003e\n\u003cb\u003eSection Three,\u003c\/b\u003e Therapeutic Removal of Uremic Toxins, describes how uremic toxins can be removed by hemodialysis, peritoneal dialysis, and oral sorbent\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eAll chapters are based on the authors' thorough review of the literature as well as their own personal laboratory and clinical experience. References at the end of each chapter provide a gateway to the literature in the field.\u003c\/p\u003e \u003cp\u003eReviewing all the latest basic and clinical research findings, \u003ci\u003eUremic Toxins\u003c\/i\u003e will help bench scientists in nephrology advance their own investigations. It will also help clinicians take advantage of the latest tested and proven treatments for the management of chronic kidney disease.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47990441246949,"sku":"NP9781118135136","price":148.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781118135136.jpg?v=1761787841","url":"https:\/\/k12savings.com\/es\/products\/uremic-toxins-isbn-9781118135136","provider":"K12savings","version":"1.0","type":"link"}