{"product_id":"the-pancreas-isbn-9781119875970","title":"The Pancreas","description":"\u003cb\u003e\u003ci\u003eThe\u003c\/i\u003e PANCREAS\u003c\/b\u003e\u003cp\u003e\u003cb\u003eThe newest edition of the essential guide to pancreatic medicine\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eThe fourth edition of \u003ci\u003eThe Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery\u003c\/i\u003e integrates the cutting-edge research of recent years to update its presentation of this fast-growing subject. It details every known disorder of the pancreas, grounding them in a thorough understanding of pancreatic function, enhanced with high quality illustration and graphs. It also includes step-by-step guidance for relevant endoscopic techniques and surgical procedures.  \u003c\/p\u003e\u003cp\u003e\u003ci\u003eThe Pancreas\u003c\/i\u003e readers will also find: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eNew comprehensive insights into three pancreatic diseases: autoimmune pancreatitis, cystic neoplasms, and neuroendocrine tumors\u003c\/li\u003e \u003cli\u003eAn editorial team with decades of clinical and research experience in the US, Europe, and Asia\u003c\/li\u003e \u003cli\u003eOver 500 downloadable illustrations for use in scientific presentations\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003e\u003ci\u003eThe Pancreas\u003c\/i\u003e is a foundational reference for clinicians and researchers in gastroenterology and gastrointestinal surgery. \u003c\/p\u003e\u003cp\u003eAbout the Companion Website xvii\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 1 Anatomy of the Pancreas 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Development of the Pancreas and Related Structures 3\u003cbr\u003e \u003ci\u003eBrian Lewis and Junhao Mao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Anatomy, Histology, and Fine Structure of the Pancreas 9\u003cbr\u003e \u003ci\u003eDaniel S. Longnecker and Elizabeth D. Thompson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Congenital and Inherited Anomalies of the Pancreas 23\u003cbr\u003e \u003ci\u003eHeiko Witt and Martin Zenker\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 2 Physiology and Pathophysiology of Pancreatic Functions 33\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4 Physiology of Acinar Cell Secretion 35\u003cbr\u003e \u003ci\u003eOle H. Petersen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Physiology of Duct Cell Secretion 48\u003cbr\u003e \u003ci\u003eWei- Yin Lin, Paramita Sarkar, and Shmuel Muallem\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Physiology and Pathophysiology of Function of Sphincter of Oddi 56\u003cbr\u003e \u003ci\u003eSavio George Barreto and James Toouli\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Neurohormonal and Hormonal Control of Pancreatic Secretion 65\u003cbr\u003e \u003ci\u003eChung Owyang and Matthew J. DiMagno\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Regulation of Pancreatic Protein Synthesis and Growth 75\u003cbr\u003e \u003ci\u003eMaria Dolors Sans and John A. Williams\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Fibrogenesis in the Pancreas: The Role of Pancreatic Stellate Cells 86\u003cbr\u003e \u003ci\u003eMinoti V. Apte, Romano C. Pirola, and Jeremy S. Wilson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Pancreatic Endocrine–Exocrine Relationship 98\u003cbr\u003e \u003ci\u003eKenichiro Furuyama and Yoshiya Kawaguchi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 3 Acute Pancreatitis 105\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11 Epidemiology and Etiology of Alcohol- Induced Pancreatitis 107\u003cbr\u003e \u003ci\u003eJeremy S. Wilson, Romano C. Pirola, and Minoti V. Apte\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 Epidemiology and Etiology of Biliary Acute Pancreatitis 119\u003cbr\u003e \u003ci\u003eIppei Ikoma, Ko Tomishima, and Hiroyuki Isayama\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Genetic Factors in Acute Pancreatitis 128\u003cbr\u003e \u003ci\u003eMitchell L. Ramsey and Georgios I. Papachristou\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 The Role of the Intestine and Mesenteric Lymph in the Development of Organ Dysfunction in Severe Acute Pancreatitis 138\u003cbr\u003e \u003ci\u003eAlistair B.J. Escott, Anthony R.J. Phillips, and John A. Windsor\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 The Role of Neurogenic Inflammation in Pancreatitis 146\u003cbr\u003e \u003ci\u003eMetrah Mohammad Nader and Jami L. Saloman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16 Molecular, Biochemical, and Metabolic Abnormalities of Acute Pancreatitis 155\u003cbr\u003e \u003ci\u003eUjjwal M. Mahajan, F. Ulrich Weiss, Markus M. Lerch, and Julia Mayerle\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17 Histopathology of Acute Pancreatitis 164\u003cbr\u003e \u003ci\u003eGünter Klöppel\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18 Severity Classification of Acute Pancreatitis 170\u003cbr\u003e \u003ci\u003eJohn A. Windsor\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e19 Clinical Assessment and Biochemical Markers to Objectify Severity and Prognosis 176\u003cbr\u003e \u003ci\u003eBettina M. Rau and Claus Schäfer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e20 Acute Pancreatitis Associated with Congenital Anomalies 185\u003cbr\u003e \u003ci\u003eCharlotte S. Austin, Christopher R. Schlieve, Andrew L. Warshaw, and Tracy C. Grikscheit\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e21 Acute Pancreatitis in Children 191\u003cbr\u003e \u003ci\u003eMark E. Lowe and Véronique D. Morinville\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e22 Acute Pancreatitis Associated with Metabolic, Infections and Drug- Related Diseases 199\u003cbr\u003e \u003ci\u003eAli A. Aghdassi, Mats L. Wiese, Quang Trung Tran, and Markus M. Lerch\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e23 Radiologic Diagnosis and Staging of Severe Acute Pancreatitis 208\u003cbr\u003e \u003ci\u003eYoshihisa Tsuji\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e24 Conservative Therapy of Acute Pancreatitis: Volume Substitution and Enteral and Parenteral Nutrition 222\u003cbr\u003e \u003ci\u003eSteven M. Hadley, Jr. and Timothy B. Gardner\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e25 ICU Treatment of Severe Acute Pancreatitis 230\u003cbr\u003e \u003ci\u003eScott R. Gunn and David C. Whitcomb\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e26 Clinical Course and Medical Treatment of Acute Pancreatitis— Use of Antibiotics in Severe Acute Pancreatitis: Indications and Limitations 238\u003cbr\u003e \u003ci\u003eRainer Isenmann and Mathias Wittau\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e27 Indications for Interventional and Surgical Treatment of Necrotizing Pancreatitis 244\u003cbr\u003e \u003ci\u003eLily V. Saadat and Thomas E. Clancy\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e28 Management of Infected Necrosis: Step- Up Approach 254\u003cbr\u003e \u003ci\u003eHester C. Timmerhuis, Marc G. Besselink, and Hjalmar C. van Santvoort\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e29 Management of Infected Pancreatic Necroses: An Endoscopic Approach 260\u003cbr\u003e \u003ci\u003eTodd H. Baron\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e30 Minimally Invasive Debridement and Lavage of Necrotizing Pancreatitis 266\u003cbr\u003e \u003ci\u003eKulbir Mann and Michael G.T. Raraty\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e31 Open Surgical Debridement of Necrotizing Pancreatitis: Late Postoperative Morbidity and Outcome 271\u003cbr\u003e \u003ci\u003eDongya Huang, Zipeng Lu, and Yi Miao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e32 Endoscopic Treatment of Acute Biliary Pancreatitis 278\u003cbr\u003e \u003ci\u003eIchiro Yasuda, Tsuyoshi Mukai, and Toru Ito\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e33 Strategies for the Treatment of Pancreatic Pseudocysts and Walled- Off Necrosis After Acute Pancreatitis: Interventional Endoscopic Approaches 284\u003cbr\u003e \u003ci\u003eGeorg Beyer and Julia Mayerle\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e34 Pseudocysts and Walled- Off Necrosis After Acute Pancreatitis: Surgical Approach 288\u003cbr\u003e \u003ci\u003eNaohiro Sata, Masaru Koizumi, and Alan Kawarai Lefor\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e35 Management of Fluid Collection in Acute Pancreatitis 294\u003cbr\u003e \u003ci\u003eGeorg Beyer, Simon Sirtl, Christoph Ammer- Herrmenau, and Albrecht Neesse\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e36 Management of Pancreatic Fistula in Acute Pancreatitis 300\u003cbr\u003e \u003ci\u003eMarta Sandini, Thilo Hackert, and Markus W. Büchler\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e37 Long- Term Outcome After Acute Pancreatitis 306\u003cbr\u003e \u003ci\u003eChristin Tjaden and Thilo Hackert\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 4 Chronic Pancreatitis 315\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e38 Definition and Classification of Chronic Pancreatitis 317\u003cbr\u003e \u003ci\u003eDavid C. Whitcomb\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e39 Molecular Understanding of Chronic Pancreatitis 326\u003cbr\u003e \u003ci\u003eBomi Lee, Monique T. Barakat, and Sohail Z. Husain\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e40 Natural History of Recurrent Acute and Chronic Pancreatitis 334\u003cbr\u003e \u003ci\u003eRohit Das, Jorge D. Machicado, and Dhiraj Yadav\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e41 Pediatric Recurrent Acute and Chronic Pancreatitis: Role of Pancreas Divisum 344\u003cbr\u003e \u003ci\u003eJiri Snajdauf, Michal Rygl, Barbora Kucerova, and Natalia Newland\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e42 Clinical and Laboratory Diagnosis of Chronic Pancreatitis 349\u003cbr\u003e \u003ci\u003eGeorg Beyer, Markus M. Lerch, and Julia Mayerle\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e43 Abdominal Imaging for the Diagnosis of Chronic Pancreatitis 357\u003cbr\u003e \u003ci\u003eAtsushi Irisawa and Akira Yamamiya\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e44 Endoscopic Ultrasound for Diagnosis of Chronic Pancreatitis Versus Pancreatic Cancer 366\u003cbr\u003e \u003ci\u003eJ. Enrique Domínguez- Muñoz, Julio Iglesias- García, José Lariño- Noia, and Daniel de la Iglesia- García\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e45 Hereditary Pancreatitis and Complex Genetic Causes 375\u003cbr\u003e \u003ci\u003eCeleste Shelton Ohlsen and David C. Whitcomb\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e46 Epidemiology and Pathophysiology of Tropical Chronic Pancreatitis 383\u003cbr\u003e \u003ci\u003eShailesh V. Shrikhande and Savio G. Barreto\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e47 CFTR- Associated Pancreatic Disease 390\u003cbr\u003e \u003ci\u003eChee Y. Ooi and Aliye Uc\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e48 Alcohol and Smoking in Chronic Pancreatitis 396\u003cbr\u003e \u003ci\u003eAtsushi Masamune, Kazuhiro Kikuta, and Kiyoshi Kume\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e49 Idiopathic and Rare Causes of Chronic Pancreatitis 404\u003cbr\u003e \u003ci\u003eMorihisa Hirota and Tooru Shimosegawa\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e50 Early Chronic Pancreatitis 412\u003cbr\u003e \u003ci\u003eKazuhiro Kikuta and Atsushi Masamune\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e51 Chronic Pancreatitis with Inflammatory Mass in the Pancreatic Head 418\u003cbr\u003e \u003ci\u003eUlrich F. Wellner, Kim C. Honselmann, and Tobias Keck\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e52 Structural Complications: Strictures, Stones, Pseudocysts, and Vascular Complications 424\u003cbr\u003e \u003ci\u003eXiaodong Tian, Xiaochao Guo, and Yinmo Yang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e53 Nutritional Evaluation and Support: An Overview 430\u003cbr\u003e \u003ci\u003eSinead N. Duggan and Stephen J. O’Keefe\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e54 Exocrine Pancreatic Insufficiency 436\u003cbr\u003e \u003ci\u003eChris E. Forsmark\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e55 Bone Disease in Chronic Pancreatitis 442\u003cbr\u003e \u003ci\u003eSinead N. Duggan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e56 Diabetes from Exocrine Pancreatic Disease 445\u003cbr\u003e \u003ci\u003eNao Fujimori, Tetsuhide Ito, and Yoshihiro Ogawa\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e57 Oxidative Stress and Antioxidants in Chronic Pancreatitis 451\u003cbr\u003e \u003ci\u003eSoumya Jagannath Mahapatra and Pramod Kumar Garg\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e58 Pain Mechanisms in Chronic Pancreatitis 460\u003cbr\u003e \u003ci\u003ePierluigi Di Sebastiano, Fabio Francesco di Mola, Tommaso Grottola, and Rossana Percario\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e59 Pain Management in Chronic Pancreatitis 467\u003cbr\u003e \u003ci\u003eLouise Kuhlmann, Søren S. Olesen, and Asbjørn M. Drewes\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e60 Adjunctive Therapy in Chronic Pancreatitis 474\u003cbr\u003e \u003ci\u003eAnna Evans Phillips\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e61 Pancreatic Cancer Risks in Chronic Pancreatitis 480\u003cbr\u003e \u003ci\u003ePatrick Maisonneuve and Albert B. Lowenfels\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e62 Evidence of Endoscopic and Interventional Treatment of Chronic Pancreatitis and Pseudocysts 486\u003cbr\u003e \u003ci\u003eJörg Schirra, Simon Sirtl MD, Markus M. Lerch, and Julia Mayerle\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e63 Major Pancreatic Resection for Chronic Pancreatitis: Indication, Goals, and Limitations 496\u003cbr\u003e \u003ci\u003eFaik G. Uzunoglu and Jakob R. Izbicki\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e64 Pancreatic Drainage Procedures: Techniques and Results 501\u003cbr\u003e \u003ci\u003eUlrich F. Wellner, Dirk Bausch, and Tobias Keck\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e65 Duodenum- Preserving Pancreatic Head Resections for Chronic Pancreatitis: Techniques and Results 506\u003cbr\u003e \u003ci\u003eHans G. Beger, Bertram Poch, Yang Yinmo, and Waldemar Uhl\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e66 Total Pancreatectomy with Islet Autotransplant 515\u003cbr\u003e \u003ci\u003eGreg Beilman, Zachary Bergman, and Melena Bellin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e67 Minimally Invasive Surgical Management of Chronic Pancreatitis 523\u003cbr\u003e \u003ci\u003eGilbert Z. Murimwa, Herbert J. Zeh III, and Matthew R. Porembka\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 5 Autoimmune Pancreatitis 533\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e68 Epidemiology of Autoimmune Pancreatitis 535\u003cbr\u003e \u003ci\u003eTerumi Kamisawa\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e69 Molecular Immunology and Pathogenesis of Autoimmune Pancreatitis 540\u003cbr\u003e \u003ci\u003eYoh Zen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e70 Clinical Manifestation of Type 1 Autoimmune Pancreatitis 546\u003cbr\u003e \u003ci\u003eTooru Shimosegawa\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e71 Clinical Manifestation of Type 2 Autoimmune Pancreatitis 554\u003cbr\u003e \u003ci\u003eNicolò de Pretis and Luca Frulloni\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e72 Clinical Diagnostic Criteria for Autoimmune Pancreatitis 561\u003cbr\u003e \u003ci\u003eTooru Shimosegawa\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e73 Laboratory Diagnosis of Autoimmune Pancreatitis 568\u003cbr\u003e \u003ci\u003eJ- Matthias Löhr and Miroslav Vujasinovic\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e74 What is the Evidence Measuring Immune Markers 573\u003cbr\u003e \u003ci\u003eShigeyuki Kawa, Takayuki Watanabe, and Norihiro Ashihara\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e75 Autoimmune Pancreatitis and IgG4- Related Disease 579\u003cbr\u003e \u003ci\u003eKazuichi Okazaki, Tsukasa Ikeura, and Kazushige Uchida\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e76 Imaging Diagnosis of Autoimmune Pancreatitis 595\u003cbr\u003e \u003ci\u003eKazuichi Okazaki, Makoto Takaoka, Tsukasa Ikeura, and Kazushige Uchida\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e77 Medical Management of Autoimmune Pancreatitis 600\u003cbr\u003e \u003ci\u003eShounak Majumder and Suresh T. Chari\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e78 Management of Intractable Autoimmune Pancreatitis 605\u003cbr\u003e \u003ci\u003eShounak Majumder and Suresh T. Chari\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e79 Long- Term Outcome After Treatment of Autoimmune Pancreatitis 609\u003cbr\u003e \u003ci\u003eLuca Frulloni and Nicolò de Pretis\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 6 Neoplastic Tumors of the Exocrine Tissue: Benign Cystic Neoplasms of the Pancreas 615\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e80 Epidemiology of Cystic Neoplasms of the Pancreas 617\u003cbr\u003e \u003ci\u003eShounak Majumder and Suresh T. Chari\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e81 Histologic Classification and Staging of Cystic Neoplasms 623\u003cbr\u003e \u003ci\u003eNoriyoshi Fukushima and Giuseppe Zamboni\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e82 Molecular Mechanisms of Cystic Neoplasia- 630\u003cbr\u003e \u003ci\u003eNickolas Papadopoulos and Ralph H. Hruban\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e83 Clinical Presentation of Pancreatic Cystic Neoplasms 638\u003cbr\u003e \u003ci\u003eMasao Tanaka\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e84 Evaluation of Cystic Lesions Using EUS, MRI, and CT 642\u003cbr\u003e \u003ci\u003eAnne Marie Lennon and Atif Zaheer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e85 Cytologic Evaluation of Cystic Neoplasms: The Role of Liquid Biopsy 652\u003cbr\u003e \u003ci\u003eAbdulwahab Ewaz and Michelle D. Reid\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e86 Natural History of Cystic Neoplasms: IPMN, MCN, SCN, and SPN 666\u003cbr\u003e \u003ci\u003eRosa Klotz, Thilo Hackert, and Markus W. Büchler\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e87 Surveillance or Surgical Treatment in Asymptomatic Cystic Neoplasm 674\u003cbr\u003e \u003ci\u003eKlaus Sahora and Carlos Fernández- del Castillo\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e88 Artificial Intelligence in the Detection and Surveillance of Cystic Neoplasms 680\u003cbr\u003e \u003ci\u003eLinda C. Chu and Elliot K. Fishman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e89 Oncologic Resection of IPMN and MCN: Open Approach―Results 688\u003cbr\u003e \u003ci\u003eMarco Del Chiaro, Michael J. Kirsch, and Richard D. Schulick\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e90 Surgical Treatment of Cystic Neoplasms: Laparoscopic and Robotic Approach—Results 693\u003cbr\u003e \u003ci\u003eBenedict Kinny- Köster, Christopher L. Wolfgang, Markus W. Büchler, and Thilo Hackert\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e91 Robotic- assisted Resection of Cystic Neoplasms 700\u003cbr\u003e \u003ci\u003eKimberly Kopecky and Jin He\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e92 Duodenum- preserving Pancreatic Head Resection for Cystic Neoplasms of the Pancreatic Head: Indications and Limitations 709\u003cbr\u003e \u003ci\u003eHans G. Beger and Bertram Poch\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e93 Pancreatic Middle Segment Resection of Cystic Neoplasms: Indications and Limitations 715\u003cbr\u003e \u003ci\u003eCalogero Iacono and Mario De Bellis\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e0005474686.indd 11 05-25-2023 11:30:31\u003c\/p\u003e \u003cp\u003e94 Tumor Enucleation for Cystic Neoplasms of the Pancreas: Indications and Limitations 723\u003cbr\u003e \u003ci\u003eRachel C. Kim, C. Max Schmidt, and Henry A. Pitt\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e95 Duodenum- preserving Pancreatic Head Resection and Local Extirpation of SPTP in Children and Adolescents: Indications and long- term results 732\u003cbr\u003e \u003ci\u003eJiri Snajdauf, Michal Rygl, Barbora Kucerova, and Natalia Newland\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e96 Management of Recurrence of Cystic Neoplasms 737\u003cbr\u003e \u003ci\u003eAnna Nießen, Christopher L. Wolfgang, Thilo Hackert, and Markus W. Büchler\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e97 Long- term Outcome after Observation and Surgical Treatment of Cystic Neoplasms: What is the Evidence? 744\u003cbr\u003e \u003ci\u003eRoberto Salvia, Giovanni Marchegiani, Giampaolo Perri, and Claudio Bassi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 7 Neoplastic Tumors of the Endocrine Pancreas: Neuroendocrine Tumors of the Pancreas 751\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e98 Epidemiology and Classification of Neuroendocrine Tumors of the Pancreas 753\u003cbr\u003e \u003ci\u003eJ.J. Mukherjee, K.O. Lee, and Gregory Kaltsas\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e99 Pathology of Neuroendocrine Neoplasms 763\u003cbr\u003e \u003ci\u003eAtsuko Kasajima and Hironobu Sasano\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e100 Molecular Genetics of Neuroendocrine Tumors 771\u003cbr\u003e \u003ci\u003eNickolas Papadopoulos and Ralph H. Hruban\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e101 What is the Origin of Pancreatic Endocrine Tumors? 781\u003cbr\u003e \u003ci\u003eAurel Perren, Iacovos P. Michael, and Ilaria Marinoni\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e102 Clinical Manifestation of Endocrine Tumors of the Pancreas 791\u003cbr\u003e \u003ci\u003eTetsuhide Ito, Keijiro Ueda, Nao Fujimori, and Robert T. Jensen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e103 Evidence of Hormonal, Laboratory, Biochemical, and Instrumental Diagnostics of Neuroendocrine Tumors of the Pancreas 799\u003cbr\u003e \u003ci\u003eK.O. Lee, Gregory Kaltsas, and J.J. Mukherjee\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e104 Pancreatic Neuroendocrine Tumors in Multiple Neoplasia Syndromes 808\u003cbr\u003e \u003ci\u003eAnja Rinke and Thomas Matthias Gress\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e105 Nonfunctioning Pancreatic Neuroendocrine Neoplasms: Diagnosis and Management Principles 815\u003cbr\u003e \u003ci\u003eTakao Ohtsuka, Yuto Hozaka, and Hiroshi Kurahara\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e106 Medical and Nucleotide Treatment of Neuroendocrine Tumors of the Pancreas 820\u003cbr\u003e \u003ci\u003eMarina Tsoli and Gregory Kaltsas\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e107 Interventional Radiology in the Treatment of Pancreatic Neuroendocrine Tumors 829\u003cbr\u003e \u003ci\u003eTetsuya Idichi, Hiroshi Kurahara, and Takao Ohtsuka\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e108 Enucleation of Benign, Neuroendocrine Tumors of the Pancreas 833\u003cbr\u003e \u003ci\u003eFrank Weber, Andreas Machens, and Henning Dralle\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e109 Duodenum- Preserving Pancreatic Head Resection or Local Extirpation of Neuroendocrine Tumors of the Pancreas Larger than 2 cm 841\u003cbr\u003e \u003ci\u003eTakashi Hatori\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e110 Individualized Surgery for Nonfunctional Pancreatic Neuroendocrine Tumors (NF- pNET) \u0026lt;2 cm: Indication, Surgical Principles, and Long- term Outcome 849\u003cbr\u003e \u003ci\u003eCharles de Ponthaud, Julien de Martino, and Sébastien Gaujoux\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e111 Surgical Treatment of Endocrine Tumors: Major Oncologic Resection 857\u003cbr\u003e \u003ci\u003eFrank Weber, Andreas Machens, and Henning Dralle\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e112 The Management of Insulinoma 865\u003cbr\u003e \u003ci\u003eKeijiro Ueda, Nao Fujimori, Robert T. Jensen, and Tetsuhide Ito\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e113 Evidence of Medical and Surgical Treatment of Gastrinoma 872\u003cbr\u003e \u003ci\u003eRyuichiro Doi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e114 Rare Neuroendocrine Tumors of Pancreas: Management and Evidence of Surgical Treatment 876\u003cbr\u003e \u003ci\u003eRyuichiro Doi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e115 Treatment of Neuroendocrine Neoplasia of the Pancreas and Biliary Tract 882\u003cbr\u003e \u003ci\u003eAndrea Frilling, Ashley K. Clift, and Vito Cicinnati\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e116 Survival after Treatment of Endocrine Tumors 891\u003cbr\u003e \u003ci\u003eZhe Cao and Taiping Zhang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 8 Neoplastic Tumors of Exocrine Tissue: Pancreatic Cancer 897\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e117 Epidemiology of Pancreatic Cancer 899\u003cbr\u003e \u003ci\u003eEvelina Mocci and Alison P. Klein\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e118 Smoking, a Risk for Pancreatic Cancer: Experimental and Clinical Data 905\u003cbr\u003e \u003ci\u003eUwe A. Wittel, Bradley R. Hall, and Surinder K. Batra\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e119 Molecular Understanding of the Development of Ductal Pancreatic Cancer 912\u003cbr\u003e \u003ci\u003eJae W. Lee, Ralph H. Hruban, and Laura D. Wood\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e120 From Tissue Turnover to the Cell of Origin of Pancreatic Cancer: An Updated View 921\u003cbr\u003e \u003ci\u003eBo Kong, Eva Thoma, and Christoph W. Michalski\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e121 Microbiome of Pancreatic Cancer: Involvement in Cancer Development and Chemo- \/Immunotherapy 928\u003cbr\u003e \u003ci\u003eXianjun Yu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e122 Molecular Subtypes and Clinical Applications 934\u003cbr\u003e \u003ci\u003eMaarten F. Bijlsma and Peter Bailey\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e123 Tumor Microenvironment: Immune Cells and Immunosuppressive Functions of Carcinoma- associated Fibroblasts and Macrophages 942\u003cbr\u003e \u003ci\u003eTony Pang, Zhihong Xu, Chamini Perera, and Minoti V. Apte\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e124 Familial Pancreatic Cancer 951\u003cbr\u003e \u003ci\u003eAlison P. Klein\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e125 Pathology of Exocrine Pancreatic Tumors 957\u003cbr\u003e \u003ci\u003eMeredith E. Pittman and Ralph H. Hruban\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e126 Pancreatic Cancer: Precancerous Lesions 969\u003cbr\u003e \u003ci\u003eMichael J. Pflüger, Michaël Noë, and Lodewijk A.A. Brosens\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e127 Clinical History and Risk Factors of Pancreatic Cancer 982\u003cbr\u003e \u003ci\u003eNorbert Hüser, Volker Aßfalg, and Helmut Friess\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e128 The Role of Endoscopic Ultrasonography in the Diagnosis and Differential Diagnosis of Neoplastic Lesions 989\u003cbr\u003e \u003ci\u003eYoshiki Hirooka, Senju Hashimoto, and Eizaburo Ohno\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e129 Radiologic Diagnosis of Pancreatic Cancer: CT, MRI 997\u003cbr\u003e \u003ci\u003eHannah S. Recht and Elliot K. Fishman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e130 Screening of Hereditary Pancreatic Cancer 1012\u003cbr\u003e \u003ci\u003eMichael Goggins\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e131 The Role of PET in Diagnosis of Pancreatic Cancer and Cancer Recurrence 1021\u003cbr\u003e \u003ci\u003eNorbert Hüser, Volker Aßfalg, Isabel Rauscher, and Helmut Friess\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e132 Tumor Markers in Pancreatic Malignancies 1028\u003cbr\u003e \u003ci\u003eShin Hamada and Atsushi Masamune\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e133 The Role of Laparoscopy and Peritoneal Cytology in the Management of Pancreatic Cancer 1033\u003cbr\u003e \u003ci\u003eYosuke Kasai, Kyoichi Takaori, and Etsuro Hatano\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e134 Clinical Assessment and Staging of Advanced Pancreatic Cancer 1037\u003cbr\u003e \u003ci\u003eJames M. Lindberg, Giles F. Whalen, and Jennifer LaFemina\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e135 Pancreatic Cancer: Indications for Resection 1047\u003cbr\u003e \u003ci\u003eAkimasa Nakao and Suguru Yamada\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e136 Pancreatoduodenectomy for Pancreatic Cancer: Short- and Long- term Outcome after Kausch- Whipple and Pylorus- preserving Pancreatoduodenectomy 1055\u003cbr\u003e \u003ci\u003eBenedict Kinny- Köster, John L. Cameron, and Jin He\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e137 Left Pancreatectomy for Body and Tail Cancer 1063\u003cbr\u003e \u003ci\u003eJony van Hilst, Mohammad Abu Hilal, and Marc G Besselink\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e138 Total Pancreatectomy: Indications and Limitations 1071\u003cbr\u003e \u003ci\u003eSeiko Hirono and Hiroki Yamaue\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e139 Minimally Invasive Resection for Pancreatic Cancer 1078\u003cbr\u003e \u003ci\u003ePatricio M. Polanco, Imad Radi, and Herbert J. Zeh iii\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e140 Robotic Resection for Pancreatic Cancer 1093\u003cbr\u003e \u003ci\u003eRenyi Qin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e141 Extended Radical Surgery for Pancreatic Cancer 1099\u003cbr\u003e \u003ci\u003eThilo Hackert, Anna Nießen, and Markus W. Büchler\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e142 Palliative Pancreatic Resection: Is It Justified? 1108\u003cbr\u003e \u003ci\u003eKira C. Steinkraus, Max Heckler, Christoph W. Michalski, and Felix J. Hüttner\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e143 Outcome of Patients after R0 Resection for Locally Advanced Pancreatic Cancer Combined with Hepatic Metastasectomy: Indications and Limitations 1113\u003cbr\u003e \u003ci\u003eTingbo Liang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e144 Bypass Surgery for Advanced Pancreatic Cancer 1117\u003cbr\u003e \u003ci\u003eEva Thoma, Thilo Hackert, Christoph W. Michalski, and Felix J. Hüttner\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e145 Endoscopic and Interventional Palliation of Pancreatic Cancer 1122\u003cbr\u003e \u003ci\u003eKazumasa Nagai and Takao Itoi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e146 Neoadjuvant Treatment of Pancreatic Cancer: Evidence for Treatment Effect 1131\u003cbr\u003e \u003ci\u003eRobert A. Wolff\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e147 Locally Advanced Pancreatic Cancer: Does the Addition of Stereotactic Body Radiation Therapy to Neoadjuvant Chemotherapy Lead to a Significant Survival Improvement after R0 Resection? 1141\u003cbr\u003e \u003ci\u003eMarco Del Chiaro, Michael J. Kirsch, and Richard D. Schulick\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e148 Adjuvant Chemotherapy in Pancreatic Cancer: First Line and Second Line Treatment— Benefits of Survival 1143\u003cbr\u003e \u003ci\u003eKulbir Mann, Robert P. Jones, Paula Ghaneh, and John P. Neoptolemos\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e149 Role of Radiation Therapy for Pancreatic Cancer 1153\u003cbr\u003e \u003ci\u003eBaho U. Sidiqi, Abhinav V. Reddy, Joseph M. Herman, and Amol K. Narang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e150 Immunotherapy for Pancreatic Cancer: Checkpoint Blockade and Vaccine Therapy 1164\u003cbr\u003e \u003ci\u003eArsen Osipov, Adrian G. Murphy, and Lei Zheng\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e151 Targeted Therapies for Pancreatic Cancer 1180\u003cbr\u003e \u003ci\u003eAnirban Maitra\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e152 Precision Cancer Medicine 1188\u003cbr\u003e \u003ci\u003eGrace Oh, Surajit Dhara, and Diane Simeone\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e153 Palliative Chemotherapy for Advanced Pancreatic Cancer: Treatment Modalities, Side- effects, and Benefits of Survival 1196\u003cbr\u003e \u003ci\u003eChristoph Springfeld and Thomas Seufferlein\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e154 Management of Pain in Pancreatic Cancer 1201\u003cbr\u003e \u003ci\u003eAnnie W. Hsu, Ayodeji Omosule, and Michael Erdek\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e155 Management of Cancer Recurrence 1208\u003cbr\u003e \u003ci\u003eOliver Strobel, Martin Loos, and Markus W. Büchler\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e156 Survival and Late Morbidity after Resection of Pancreatic Cancer 1218\u003cbr\u003e \u003ci\u003eAvinoam Nevler and Charles J. Yeo\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 9 Periampullary Cancers and Tumors Other Than Pancreatic Cancer 1233\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e157 Periampullary Tumors: Clinical Presentation and Diagnostic Strategies 1235\u003cbr\u003e \u003ci\u003eJon M. Harrison and Keith D. Lillemoe\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e158 Histology and Genetics of Cancer of the Papilla, Distal Common Bile Duct, and Duodenum 1242\u003cbr\u003e \u003ci\u003eYue Xue, Michelle D. Reid, and Volkan Adsay\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e159 Adenoma and Adenocarcinoma of the Ampulla of Vater: Diagnosis and Management 1254\u003cbr\u003e \u003ci\u003eSahin Coban, Omer Basar, and William R. Brugge\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e160 Endoscopic Treatment of Adenomas of the Ampulla of Vater: Techniques, Results, Benefits, and Limitations 1264\u003cbr\u003e \u003ci\u003eNatsuyo Yamamoto and Hiroyuki Isayama\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e161 Surgical Treatment of Papillary and Ampullary Tumors: Management and Long- term Results 1272\u003cbr\u003e \u003ci\u003eNorbert Hüser, Volker Aßfalg, and Helmut Friess\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e162 Surgical Treatment of Duodenal Cancer 1281\u003cbr\u003e \u003ci\u003eFuyuhiko Motoi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e163 Surgical Treatment of Distal Cholangiocarcinoma 1284\u003cbr\u003e \u003ci\u003eShunsuke Onoe, Yukihiro Yokoyama, and Tomoki Ebata\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e164 Adjuvant and Palliative Chemotherapy of Periampullary Cancers 1291\u003cbr\u003e \u003ci\u003eArachchige D.N.R. Ponweera, Paula Ghaneh, and John P. Neoptolemos\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e165 Long- term Survival After Resection of Periampullary Cancer 1299\u003cbr\u003e \u003ci\u003eHideyuki Yoshitomi, Masayuki Ohtsuka, and Masaru Miyazaki\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 10 Transplantation of the Pancreas 1309\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e166 Transplantation of Pancreatic Islets 1311\u003cbr\u003e \u003ci\u003eJoseph Sushil Rao, Melena D. Bellin, and Bernhard J. Hering\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e167 Transplantation of the Pancreas 1323\u003cbr\u003e \u003ci\u003eRainer W.G. Gruessner and Angelika C. Gruessner\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 1333\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eHans G. Beger, MD, FACS (Hon.), JSS (Hon.), CSS (Hon.),\u003c\/b\u003e Professor Emeritus of Surgery, University of Ulm, Ulm, Germany. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eMarkus W. Büchler, MD, FACS (Hon.), FRCS (Hon.), FASA (Hon.)\u003c\/b\u003e Professor of Surgery, University of Heidelberg, Heidelberg, Germany. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eRalph H. Hruban, MD,\u003c\/b\u003e Baxley Professor and Director, Department of Pathology and Director of the Sol Goldman Pancreatic Research Center, Johns Hopkins University School of Medicine, Baltimore, USA. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eJulia Mayerle, MD,\u003c\/b\u003e Professor of Internal Medicine, Gastroenterology and Hepatology, Chair Department of Medicine II, LMU Klinikum, Ludwig-Maximilians-University, Munich, Germany. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eJohn P. Neoptolemos, MA, MB, BCHIR, MD FRCS, FMEDSCI, MAE\u003c\/b\u003e Professor of Surgery, Department of Surgery, University of Heidelberg, Heidelberg, Germany. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eTooru Shimosegawa, MD, PhD,\u003c\/b\u003e Professor Emeritus Department of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eAndrew L. Warshaw, MD, FACS, FRCSEd (Hon.),\u003c\/b\u003e W. Gerald Austen Distinguished Professor of Surgery, Harvard Medical School, and Surgeon-in-Chief Emeritus, Massachusetts General Hospital, Boston, USA. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eDavid C. Whitcomb, MD, PhD,\u003c\/b\u003e Professor of Medicine, Cell Biology \u0026amp; Physiology, and Human Genetics,  Division of Gastroenterology, Hepatology, and Nutrition, University of Pittsburgh and UPMC, Pennsylvania, USA. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eYupei Zhao, MD, FICS (Hon.), FACS (Hon.), FRCS (Engl) (Hon.), FCSHK (Hon.),\u003c\/b\u003e Professor of Surgery, Department of General Surgery, Peking Union Medical College Hospital, Beijing, P.R. China.   \u003c\/p\u003e\u003cp\u003e\u003cb\u003eThe newest edition of the essential guide to pancreatic medicine\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eThe fourth edition of \u003ci\u003eThe Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery\u003c\/i\u003e integrates the cutting-edge research of recent years to update its presentation of this fast-growing subject. It details every known disorder of the pancreas, grounding them in a thorough understanding of pancreatic function, enhanced with high quality illustration and graphs. It also includes step-by-step guidance for relevant endoscopic techniques and surgical procedures.  \u003c\/p\u003e\u003cp\u003e\u003ci\u003eThe Pancreas\u003c\/i\u003e readers will also find: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eNew comprehensive insights into three pancreatic diseases: autoimmune pancreatitis, cystic neoplasms, and neuroendocrine tumors\u003c\/li\u003e \u003cli\u003eAn editorial team with decades of clinical and research experience in the US, Europe, and Asia\u003c\/li\u003e \u003cli\u003eOver 500 downloadable illustrations for use in scientific presentations\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003e\u003ci\u003eThe Pancreas\u003c\/i\u003e is a foundational reference for clinicians and researchers in gastroenterology and gastrointestinal surgery.\u003c\/p\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":47990306767077,"sku":"NP9781119875970","price":342.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781119875970.jpg?v=1761787288","url":"https:\/\/k12savings.com\/es\/products\/the-pancreas-isbn-9781119875970","provider":"K12savings","version":"1.0","type":"link"}