{"product_id":"the-gut-microbiota-in-health-and-disease-isbn-9781119904755","title":"The Gut Microbiota in Health and Disease","description":"\u003cb\u003eThe Gut Microbiota in Health and Disease\u003c\/b\u003e \u003cp\u003e\u003cb\u003eAn accessible overview of the varied microorganisms of the gut\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eThe human gut contains an extraordinary array of microorganisms existing in intricate symbiosis with the body. The gut microbiota plays a crucial role in maintaining overall gut health and warding off disease. With up to 15% of the global population suffering from Irritable Bowel Syndrome (IBS) caused by improper composition of gut microbiota, understanding these organisms and their vital contribution to human health has never been more important. \u003c\/p\u003e\u003cp\u003e\u003ci\u003eThe Gut Microbiota in Health and Disease\u003c\/i\u003e provides a concise, accessible introduction to gut microbiota and their contribution to human health. It offers not only an overview of the relevant microorganisms and their roles in the body, but also extended discussion of diseases caused by gut dysbiosis. It presents a crucial window into this growing body of research into a critical area of overall human health. \u003c\/p\u003e\u003cp\u003e\u003ci\u003eThe Gut Microbiota in Health and Disease\u003c\/i\u003e, readers will also find: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eDetailed analysis of dysbiotic health conditions including obesity, diabetes, and more\u003c\/li\u003e \u003cli\u003eThorough treatment of molecular techniques for the analysis gut microbial composition\u003c\/li\u003e \u003cli\u003eDiscussion of the lowering diversity of bacteria in the gut and the corresponding impact on global health\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003e\u003ci\u003eThe Gut Microbiota in Health and Disease\u003c\/i\u003e is essential for researchers and clinicians working in immunology, gastroenterology, clinical microbiology, and related fields, as well as for clinical dieticians and postgraduate or medical students studying in these areas. \u003c\/p\u003e\u003cp\u003eList of Contributors xiii\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Structural and Dynamics of Healthy Adult's Microbiota 1\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eMahdi Hussein Abdelrazig\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1.1 Introduction 1\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Composition and Diversity of Gut Microbiota 7\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eLisa F.M. Lee Nen That and Jessica Pandohee\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2.1 Introduction 7\u003c\/p\u003e \u003cp\u003e2.2 Composition and Diversity of Gut Microbiota Throughout Lifespan 8\u003c\/p\u003e \u003cp\u003e2.3 Composition of Bacterial Community in the Different Sections of the Gastrointestinal Tract 9\u003c\/p\u003e \u003cp\u003e2.4 Stability, Resilience, and Functional Redundancy 10\u003c\/p\u003e \u003cp\u003e2.5 Interactions in the Gut Microbiota 11\u003c\/p\u003e \u003cp\u003e2.6 Conclusion 13\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Factors Affecting Composition and Diversity of Gut Microbiota: A Disease Hallmark 17\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eRohan Samir Kumar Sachan, Khushboo, Inderpal Devgon, Atif Khurshid Wani, Nahid Akhtar, Tahir ul Gani Mir, Ab Waheed Wani, and Ajit Prakash\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction 17\u003c\/p\u003e \u003cp\u003e3.2 Composition of Gut Microbiota 18\u003c\/p\u003e \u003cp\u003e3.3 Factors Affecting Gut Microbiota 19\u003c\/p\u003e \u003cp\u003e3.4 Modulation of Gut Microbiota 23\u003c\/p\u003e \u003cp\u003e3.5 Gut Microbiota Hallmark in Disease Condition 25\u003c\/p\u003e \u003cp\u003e3.6 Conclusion 26\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Antibiotic-Induced Changes in the Composition of the Gut Microbiome 31\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eGholamreza Abdi, Abu Saeid, Ab Waheed Wani, and Vishal Johar\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction 31\u003c\/p\u003e \u003cp\u003e4.2 Gut Microbiota Composition 32\u003c\/p\u003e \u003cp\u003e4.3 Antibiotic-induced Changes in the Composition of the Microbiota 32\u003c\/p\u003e \u003cp\u003e4.4 Conclusion 38\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Dysbiosis and its Varied Impacts 41\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eRajani Sharma and Kunal Kumar\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5.1 Introduction 41\u003c\/p\u003e \u003cp\u003e5.2 Causes of Dysbiosis 41\u003c\/p\u003e \u003cp\u003e5.3 Dysbiosis, Immune System, and Associated Diseases 44\u003c\/p\u003e \u003cp\u003e5.4 Intestinal Colonisation in Neonates and Dysbiosis 48\u003c\/p\u003e \u003cp\u003e5.5 Treatment or Therapeutics 48\u003c\/p\u003e \u003cp\u003e5.6 Conclusion 50\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Connection between Dysbiosis and Diet 55\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eSagnik Nag, Nimmy Srivastava, Rohan Dutta, Aparajita Bagchi, Israrahmed Adur, and Shuvam Chakraborty\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction 55\u003c\/p\u003e \u003cp\u003e6.2 Different Dietary Patterns Resulting in Dysbiosis 59\u003c\/p\u003e \u003cp\u003e6.3 Future Prospects in Establishing a Healthy Connection between Diet and Gut Microbiota 68\u003c\/p\u003e \u003cp\u003e6.4 Conclusion 70\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Composition of Gut Microbiota and Clostridium difficile 81\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eJissin Mathew and Anu Jacob\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7.1 Introduction 81\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Gut Microbiota and Obesity 87\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eShaimaa H. Negm\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8.1 Introduction 87\u003c\/p\u003e \u003cp\u003e8.2 Obesity Epidemic: Statistics and General Background 87\u003c\/p\u003e \u003cp\u003e8.3 Gut Microbiota and Obesity 87\u003c\/p\u003e \u003cp\u003e8.4 Adiposity and Gut Microbiota 90\u003c\/p\u003e \u003cp\u003e8.5 Gut Microbiota Modification 92\u003c\/p\u003e \u003cp\u003e8.6 The Microbiota and Obesity Interactions 93\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Gut Microbiota and Cardiovascular Disease 99\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eShaimaa H. Negm\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9.1 Introduction 99\u003c\/p\u003e \u003cp\u003e9.2 Gut Microbiota and CVD 100\u003c\/p\u003e \u003cp\u003e9.3 Gut Microbiota Composition in Cardiovascular Disease 101\u003c\/p\u003e \u003cp\u003e9.4 Gut Microbiota Function in Cardiovascular Disease 103\u003c\/p\u003e \u003cp\u003e9.5 Gut Microbiota as Therapeutic Strategies for Cardiovascular Disease 104\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Gut Microbiota and Inflammatory Bowel Diseases 109\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eAnu Jacob and Jissin Mathew\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10.1 Introduction 109\u003c\/p\u003e \u003cp\u003e10.2 Intestinal Microbiome in IBD Patients 110\u003c\/p\u003e \u003cp\u003e10.3 Interventions for the Treatment of IBD 113\u003c\/p\u003e \u003cp\u003e10.4 Conclusion 115\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Gut Microbiota and Diabetes 121\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eAnkita Dey, Ridashisha Rymbai, Hriiziini Monica, and Jutishna Bora\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11.1 Introduction 121\u003c\/p\u003e \u003cp\u003e11.2 Gut Microbiota 121\u003c\/p\u003e \u003cp\u003e11.3 Role of Gut Microbiota in Diabetes 122\u003c\/p\u003e \u003cp\u003e11.4 Alteration in Gut Microbiota Composition in T1 and T2 Diabetes 124\u003c\/p\u003e \u003cp\u003e11.5 Diabetic Complications 127\u003c\/p\u003e \u003cp\u003e11.6 Therapeutic Approaches 128\u003c\/p\u003e \u003cp\u003e11.7 Conclusion 129\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Novel Therapeutic Strategies Targeting Gut Microbiota to Treat Diseases 133\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eShaimaa H. Negm\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12.1 Introduction 133\u003c\/p\u003e \u003cp\u003e12.2 Changes in the Composition of the Gut Microbiota in Patients with T1D 133\u003c\/p\u003e \u003cp\u003e12.3 The Potential Role of the Gut Microbiota in the Development of T1D 134\u003c\/p\u003e \u003cp\u003e12.4 Changes in the Composition of the Gut Microbiota in Patients with T2D 135\u003c\/p\u003e \u003cp\u003e12.5 The Potential Role of the Gut Microbiota in the Development of T2D 136\u003c\/p\u003e \u003cp\u003e12.7 Preventive and Therapeutic Perspectives Including the Gut Microbiota 137\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Understanding the Role of Microbiota in Cancer 143\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eParneet Kaur , Lisa F. M. Lee Nen That , Saurabh Kulshreshtha , and Jessica Pandohee\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13.1 Introduction 143\u003c\/p\u003e \u003cp\u003e13.2 Role of Microbiota in Cancers 144\u003c\/p\u003e \u003cp\u003e13.3 Mechanism in which Microbiota Kill Cancer Cells 146\u003c\/p\u003e \u003cp\u003e13.4 Microbiota that Promote Health Post Cancer Treatment 147\u003c\/p\u003e \u003cp\u003e13.5 Conclusion 147\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Impact of Gut Microbiota on Mental Health in Humans 153\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eSagnik Nag, Ankita Saini, Richismita Hazra, and Jutishna Bora\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14.1 Introduction 153\u003c\/p\u003e \u003cp\u003e14.2 Gut Dysbiosis and Mental Health Disorders 156\u003c\/p\u003e \u003cp\u003e14.3 Psychiatric Medication and the Microbiome 161\u003c\/p\u003e \u003cp\u003e14.4 Probiotic Treatments for Mental Health Disorders 161\u003c\/p\u003e \u003cp\u003e14.5 Future Therapeutic Approach 163\u003c\/p\u003e \u003cp\u003e14.6 Conclusion 164\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Interaction between Gut Microbiota and Central and Enteric Nervous Systems: The Gut--Brain Axis Concept 169\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eMohamed Hussein Arbab\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15.1 Introduction 169\u003c\/p\u003e \u003cp\u003e15.2 The Neuronal Communications 170\u003c\/p\u003e \u003cp\u003e15.3 Neuroimmune Regulation of Inflammation and Cellular Defence 171\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 Immune-Modulation and Gut Microbiome 179\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eSarah Adjei-Fremah, Mulumebet Worku, and Salam Ibrahim\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16.1 Introduction 179\u003c\/p\u003e \u003cp\u003e16.2 Dysbiosis of the Gut Microbiome 180\u003c\/p\u003e \u003cp\u003e16.3 Gut Dysbiosis and Diseases 180\u003c\/p\u003e \u003cp\u003e16.4 Gut Microbiome-Mediated Immune Modulation 182\u003c\/p\u003e \u003cp\u003e16.5 Gut Microbiome Modulators 183\u003c\/p\u003e \u003cp\u003e16.6 Prebiotics 185\u003c\/p\u003e \u003cp\u003e16.7 Probiotics 185\u003c\/p\u003e \u003cp\u003e16.8 Galectins, Gut Microbiome, and Immune Modulation 186\u003c\/p\u003e \u003cp\u003e16.9 Conclusion 186\u003c\/p\u003e \u003cp\u003e\u003cb\u003e17 Current Molecular Technologies for Assaying the Gut Microbiota: Next-generation DNA Sequencing 193\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eHarshit Sajal, Yuvaraj Sivamani, and Sumitha Elayaperumal\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17.1 Introduction and Overview 193\u003c\/p\u003e \u003cp\u003e17.2 Research on the Gut Microbiome Using Next-generation Sequencing 194\u003c\/p\u003e \u003cp\u003e17.3 Collection, Storage, and DNA Extraction Methodology 199\u003c\/p\u003e \u003cp\u003e17.4 DNA Sequencing and Post-processing 201\u003c\/p\u003e \u003cp\u003e17.5 Metabolic Modelling of the Human Gut Microbiome 201\u003c\/p\u003e \u003cp\u003e\u003cb\u003e18 The Role of Probiotics and Prebiotics in Gut Modulation 205\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eUsman Atique, Muhammad Altaf, Dwaipayan Sinha, Shakira Ghazanfar, Md. Ayenuddin Haque, and Shahana Chowdhury\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18.1 Introduction 205\u003c\/p\u003e \u003cp\u003e18.2 Probiotics and Prebiotics: A Functional Perspective 206\u003c\/p\u003e \u003cp\u003e18.3 Diet and its Effect on Gut Microbiota 208\u003c\/p\u003e \u003cp\u003e18.4 Modification of Intestinal Microbiota by the Application of Probiotics and Prebiotics 209\u003c\/p\u003e \u003cp\u003e18.5 Prebiotics and Gut Immunity 211\u003c\/p\u003e \u003cp\u003e18.6 Conclusions and Future Research 211\u003c\/p\u003e \u003cp\u003e\u003cb\u003e19 Probiotics, Prebiotics, and Synbiotics: A Potential Source for a Healthy Gut 217\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eVandana Singh and Bushra Shaida\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e19.1 Introduction 217\u003c\/p\u003e \u003cp\u003e19.2 Prebiotics 218\u003c\/p\u003e \u003cp\u003e19.3 Probiotics 221\u003c\/p\u003e \u003cp\u003e19.4 Synbiotics 227\u003c\/p\u003e \u003cp\u003e19.5 Conclusion 228\u003c\/p\u003e \u003cp\u003e\u003cb\u003e20 Current Status and Efficacy of Fecal Microbiota Transplantation for Patients Suffering from Irritable Bowel Syndrome 231\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eMohamed Hussein Arbab\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e20.1 Introduction 231\u003c\/p\u003e \u003cp\u003e20.2 Donor Selection 232\u003c\/p\u003e \u003cp\u003e20.3 Safety Issues of FMT for IBS 233\u003c\/p\u003e \u003cp\u003e20.4 Possible Mechanisms Underlying the Effects of FMT 234\u003c\/p\u003e \u003cp\u003e20.5 Conclusion and Perspective 234\u003c\/p\u003e \u003cp\u003eReferences 235\u003c\/p\u003e \u003cp\u003eIndex 239\u003c\/p\u003e  \u003cp\u003e\u003cb\u003eNimmy Srivastava, PhD,\u003c\/b\u003e works as an Assistant Professor of Biotechnology in the Amity Institute of Biotechnology, Amity University Jharkhand. She obtained her PhD in the field of Genetics in 2015 and has received various research fellowships from prestigious organizations including ICFRE and BARC-BRNS (India). \u003c\/p\u003e\u003cp\u003e\u003cb\u003eSalam A. Ibrahim, PhD,\u003c\/b\u003e is a Professor of the Food and Nutritional Science program in the Department of Family and Consumer Science at North Carolina Agricultural and Technical State University, North Carolina, USA. He is also the faculty coach for the dairy products evaluation team at the University and has published extensively on food safety, microbiology, and dairy food fermentation. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eJayeeta Chattopadhyay, PhD,\u003c\/b\u003e is an Associate Professor at Amity University Jharkhand, India. She obtained her PhD in new energy engineering with the best doctoral thesis award from Seoul National University of Science and Technology, South Korea (2010). She is also the recipient of the prestigious Fast Track Young Scientist Award, the Department of Science (India). Her research area covers synthesis of special shaped nano-materials. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eMohamed H. Arbab, PhD,\u003c\/b\u003e is an Associate Professor of Medical Microbiology, at Omdurman Ahlia University, Sudan. He has researched and published extensively on infectious diseases, immunopathology, antimicrobial resistance, and related subjects. \u003c\/p\u003e\u003cp\u003e   \u003c\/p\u003e\u003cp\u003e\u003cb\u003eAn accessible overview of the varied microorganisms of the gut\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eThe human gut contains an extraordinary array of microorganisms existing in intricate symbiosis with the body. The gut microbiota plays a crucial role in maintaining overall gut health and warding off disease. With up to 15% of the global population suffering from Irritable Bowel Syndrome (IBS) caused by improper composition of gut microbiota, understanding these organisms and their vital contribution to human health has never been more important. \u003c\/p\u003e\u003cp\u003e\u003ci\u003eThe Gut Microbiota in Health and Disease\u003c\/i\u003e provides a concise, accessible introduction to gut microbiota and their contribution to human health. It offers not only an overview of the relevant microorganisms and their roles in the body, but also extended discussion of diseases caused by gut dysbiosis. It presents a crucial window into this growing body of research into a critical area of overall human health. \u003c\/p\u003e\u003cp\u003e\u003ci\u003eThe Gut Microbiota in Health and Disease\u003c\/i\u003e, readers will also find: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eDetailed analysis of dysbiotic health conditions including obesity, diabetes, and more\u003c\/li\u003e \u003cli\u003eThorough treatment of molecular techniques for the analysis gut microbial composition\u003c\/li\u003e \u003cli\u003eDiscussion of the lowering diversity of bacteria in the gut and the corresponding impact on global health\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003e\u003ci\u003eThe Gut Microbiota in Health and Disease\u003c\/i\u003e is essential for researchers and clinicians working in immunology, gastroenterology, clinical microbiology, and related fields, as well as for clinical dieticians and postgraduate or medical students studying in these areas.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47990245097701,"sku":"NP9781119904755","price":115.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9781119904755.jpg?v=1761787044","url":"https:\/\/k12savings.com\/es\/products\/the-gut-microbiota-in-health-and-disease-isbn-9781119904755","provider":"K12savings","version":"1.0","type":"link"}