{"product_id":"the-design-and-analysis-of-sequential-clinical-trials-isbn-9780471975502","title":"The Design and Analysis of Sequential Clinical Trials","description":"This book details all aspects of sequential clinical trials from preliminary planning, through the monitoring of the trial, to the final analysis of the results. Emphasis is placed on the triangular test and other procedures based on straight line stopping boundaries. These methods allow for frequent or occasional interim analyses and permit the analysis of a wide variety of patient responses. Alternative procedures are also covered in detail, and these include -spending function methods, repeated confidence intervals and Bayesian approaches to sequential clinical trials.Alles über Planung, Durchführung und Analyse sequentieller klinischer Versuche - das sind Versuche, bei denen erste Daten von Patienten bereits ausgewertet werden können, während der Versuch mit neuen Testpersonen fortgeführt wird. Die überarbeitete Neuauflage bezieht sich unter anderem auf die Software PEST (Planning and Education of Sequential Trials). Clinical Trials.\u003cbr\u003e \u003cbr\u003e Allocating Patients to Treatments.\u003cbr\u003e \u003cbr\u003e Measurement of Treatment Difference.\u003cbr\u003e \u003cbr\u003e The Design of a Sequential Trial Using the Boundaries Approach.\u003cbr\u003e \u003cbr\u003e The Analysis of a Sequential Trial.\u003cbr\u003e \u003cbr\u003e Alternative Approaches to the Design and Analysis of Sequential Clinical Trials.\u003cbr\u003e \u003cbr\u003e Prognostic Factors.\u003cbr\u003e \u003cbr\u003e The Comparison of More than Two Treatments.\u003cbr\u003e \u003cbr\u003e Implementation of Sequential Methods: Some Examples.\u003cbr\u003e \u003cbr\u003e References.\u003cbr\u003e \u003cbr\u003e Appendix.\u003cbr\u003e \u003cbr\u003e Index.  Aus dem Inhalt:\u003cbr\u003e Clinical Trials;\u003cbr\u003e Allocating Patients to Treatments;\u003cbr\u003e Measurement of Treatment Differences;\u003cbr\u003e Using the Boundary Approach;\u003cbr\u003e Analysis of a sequential Trial;\u003cbr\u003e Alternative Approaches;\u003cbr\u003e Prognostic Factors;\u003cbr\u003e Comparison of More than Two treatments;\u003cbr\u003e Examples;\u003cbr\u003e References;\u003cbr\u003e Index. \"...This book is clear, it provides many details and is well written...\" (Statistical Methods in Medical Research, No.11, 2002)  \u003cp\u003eJohn Whitehead is the author of The Design and Analysis of Sequential Clinical Trials, Revised, 2nd Edition, published by Wiley.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47990205382885,"sku":"NP9780471975502","price":181.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1842\/7735\/files\/9780471975502.jpg?v=1761786898","url":"https:\/\/k12savings.com\/es\/products\/the-design-and-analysis-of-sequential-clinical-trials-isbn-9780471975502","provider":"K12savings","version":"1.0","type":"link"}