Tandem Organic Reactions

The importance of tandem reactions is evident--besides their pragmatic value, they have an aesthetic appeal. The author presents a survey of these reactions that will rivet the attention of numerous chemists to their merits and utility as well as stimulate design and discovery of new sets of tandem reactions. Coverage includes Aldol condensation, Michael Reaction, Dieckmann cyclization, thermal and free radical processes, stitching reactions and much more. Aldol Condensation.

Michael Reactions.

Tandem Vicinal Difunctionalization of Alkenes and Alkynes.

Dieckmann and Claisen Cyclizations.

Mannich Reaction.

Diels-Alder Reactions.

Other Cycloadditions.

Retro-Diels-Alder and Cheletropic Reactions.

Electrocyclic Reactions.

Ene, Retro-Ene, and Some Other Thermal Reactions.

Sigmatropic Rearrangements.

Rearrangements and Fragmentations.

Free Radical Reactions.

Miscellaneous Tandem Reactions.

References.

Index.

TSE-LOK HO is Professor of Organic Chemistry at National Chiao Tung University in Taiwan. His research interests are in organic synthesis, including total synthesis of natural products and methodology. He has written 12 books, including, most recently, Stereoselectivity in Synthesis, available from Wiley. Dr. Ho holds degrees from National Taiwan University and the University of New Brunswick, Canada.